IE38554B1 - Fluoro-substituted thiaxanthene derivatives - Google Patents
Fluoro-substituted thiaxanthene derivativesInfo
- Publication number
- IE38554B1 IE38554B1 IE2161/73A IE216173A IE38554B1 IE 38554 B1 IE38554 B1 IE 38554B1 IE 2161/73 A IE2161/73 A IE 2161/73A IE 216173 A IE216173 A IE 216173A IE 38554 B1 IE38554 B1 IE 38554B1
- Authority
- IE
- Ireland
- Prior art keywords
- compounds
- nme
- reacting
- fluorothiaxanth
- ylidene
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 6
- GVNVAWHJIKLAGL-UHFFFAOYSA-N 2-(cyclohexen-1-yl)cyclohexan-1-one Chemical compound O=C1CCCCC1C1=CCCCC1 GVNVAWHJIKLAGL-UHFFFAOYSA-N 0.000 abstract 2
- 101150065749 Churc1 gene Proteins 0.000 abstract 2
- 102100038239 Protein Churchill Human genes 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 2
- 150000001298 alcohols Chemical class 0.000 abstract 2
- LFJMRGTVKNCAKR-UHFFFAOYSA-N 1-(3-chloropropyl)-4-(2-methoxyethyl)piperazine Chemical compound COCCN1CCN(CCCCl)CC1 LFJMRGTVKNCAKR-UHFFFAOYSA-N 0.000 abstract 1
- -1 2-dimethylsulphamoyl-6-fluorothiaxanth-9-ylidene Chemical group 0.000 abstract 1
- CIBQTAHLHLHRGX-UHFFFAOYSA-N 3-fluoro-9H-thioxanthene Chemical class FC=1C=CC=2CC3=CC=CC=C3SC=2C=1 CIBQTAHLHLHRGX-UHFFFAOYSA-N 0.000 abstract 1
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000701 neuroleptic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- YRHRIQCWCFGUEQ-UHFFFAOYSA-N thioxanthen-9-one Chemical compound C1=CC=C2C(=O)C3=CC=CC=C3SC2=C1 YRHRIQCWCFGUEQ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/14—[b,f]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5691072A GB1453828A (en) | 1972-12-08 | 1972-12-08 | Fluoro-substituted thiaxanthene derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE38554L IE38554L (en) | 1974-06-08 |
| IE38554B1 true IE38554B1 (en) | 1978-04-12 |
Family
ID=10477876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2161/73A IE38554B1 (en) | 1972-12-08 | 1973-11-29 | Fluoro-substituted thiaxanthene derivatives |
Country Status (19)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ189108A (en) * | 1977-12-29 | 1982-02-23 | Kefalas As | 2-methylthio-6-fluoro-9-(1-methyl-4-piperidylidene)-thioxanthene and pharmaceutical compositions intermediate 2-methylthio-6-fluoro-9-(1-methyl-4-piperidyl)-thioxanthen-9-ol |
| US5173489A (en) * | 1986-04-10 | 1992-12-22 | The Dupont Merck Pharmaceutical Co. | α,α-disubstituted aromatics and heteroaromatics as cognition enhancers |
| GB8628903D0 (en) * | 1986-12-03 | 1987-01-07 | Lunbeck A S H | Neuroleptic compounds |
| US6127385A (en) * | 1999-03-04 | 2000-10-03 | Pharmaquest Limited | Method of treating depression using l-threo-methylphenidate |
| US6395752B1 (en) * | 1999-03-04 | 2002-05-28 | Pharmaquest Limited | Method of treating depression using 1-threo-methylphenidate |
| MX2009007235A (es) * | 2007-01-05 | 2009-10-16 | Bkg Pharma Aps | "derivados de tioxanteno utiles para el tratamiento de enfermedades infecciosas.". |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE585338A (enrdf_load_stackoverflow) * | 1958-12-04 | |||
| FR1463787A (fr) * | 1963-10-14 | 1966-07-22 | Pfizer & Co C | Composés de phosphonium aminoalcoyl-trisubstitués, dérivés de tels composés, et procédés pour leur préparation |
-
1972
- 1972-12-08 GB GB5691072A patent/GB1453828A/en not_active Expired
-
1973
- 1973-11-23 CH CH1585676A patent/CH592085A5/xx not_active IP Right Cessation
- 1973-11-23 CH CH1652873A patent/CH590272A5/xx not_active IP Right Cessation
- 1973-11-23 FI FI3618/73A patent/FI57410C/fi active
- 1973-11-23 NL NL7316035A patent/NL7316035A/xx not_active Application Discontinuation
- 1973-11-26 ZA ZA738990A patent/ZA738990B/xx unknown
- 1973-11-28 DE DE2359359A patent/DE2359359C3/de not_active Expired
- 1973-11-29 IE IE2161/73A patent/IE38554B1/xx unknown
- 1973-11-29 AT AT1000373A patent/AT332395B/de not_active IP Right Cessation
- 1973-12-03 ES ES421098A patent/ES421098A1/es not_active Expired
- 1973-12-06 CS CS8429A patent/CS176259B2/cs unknown
- 1973-12-07 BE BE138618A patent/BE808347A/xx not_active IP Right Cessation
- 1973-12-07 JP JP48136256A patent/JPS594436B2/ja not_active Expired
- 1973-12-07 PL PL1973178366A patent/PL95266B1/pl unknown
- 1973-12-07 SE SE7316567A patent/SE400287B/xx unknown
- 1973-12-07 AR AR251406A patent/AR202805A1/es active
- 1973-12-07 FR FR7343766A patent/FR2209573B1/fr not_active Expired
- 1973-12-07 NO NO4693/73A patent/NO138806C/no unknown
- 1973-12-07 HU HUKE936A patent/HU167778B/hu unknown
- 1973-12-10 DK DK667273A patent/DK145576C/da active
-
1974
- 1974-11-19 AR AR256579A patent/AR202672A1/es active
-
1976
- 1976-01-14 ES ES444294A patent/ES444294A1/es not_active Expired
Also Published As
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