ID27137A - Penghambat-penghambat amidino dan guanidino azetidino triptase - Google Patents

Penghambat-penghambat amidino dan guanidino azetidino triptase

Info

Publication number
ID27137A
ID27137A IDW20002643A ID20002643A ID27137A ID 27137 A ID27137 A ID 27137A ID W20002643 A IDW20002643 A ID W20002643A ID 20002643 A ID20002643 A ID 20002643A ID 27137 A ID27137 A ID 27137A
Authority
ID
Indonesia
Prior art keywords
triptase
azetidino
guanidino
amidino
obstacles
Prior art date
Application number
IDW20002643A
Other languages
English (en)
Indonesian (id)
Inventor
Bisacchi Gregory
Slusarchyk William
Treuner Uwe
Sutton James
Zahler Robert
Seiler Steven
David R Kronenthal
Michael E Randazzo
Xu Zhongmin
Shi Zhong Ping
Mark D Schwinden
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of ID27137A publication Critical patent/ID27137A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IDW20002643A 1998-06-25 1999-06-18 Penghambat-penghambat amidino dan guanidino azetidino triptase ID27137A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9063698P 1998-06-25 1998-06-25

Publications (1)

Publication Number Publication Date
ID27137A true ID27137A (id) 2001-03-01

Family

ID=22223632

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20002643A ID27137A (id) 1998-06-25 1999-06-18 Penghambat-penghambat amidino dan guanidino azetidino triptase

Country Status (24)

Country Link
EP (1) EP1089973B1 (de)
JP (1) JP2002518478A (de)
KR (1) KR20010053173A (de)
CN (1) CN1202081C (de)
AR (1) AR018945A1 (de)
AT (1) ATE309211T1 (de)
AU (1) AU752320B2 (de)
BR (1) BR9911373A (de)
CA (1) CA2336003A1 (de)
DE (1) DE69928257T2 (de)
ES (1) ES2249017T3 (de)
HU (1) HUP0104308A3 (de)
ID (1) ID27137A (de)
IL (1) IL140414A0 (de)
NO (1) NO20006380D0 (de)
NZ (1) NZ507627A (de)
PE (1) PE20000729A1 (de)
PL (1) PL345067A1 (de)
RU (1) RU2211832C2 (de)
TR (1) TR200003859T2 (de)
TW (1) TW548270B (de)
UY (1) UY25580A1 (de)
WO (1) WO1999067215A1 (de)
ZA (1) ZA200006028B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1698375B1 (de) 2003-12-25 2014-04-02 Ono Pharmaceutical Co., Ltd. Azetidin-ringverbindungen und diese enthaltende arzneimittel
WO2006062110A1 (ja) * 2004-12-06 2006-06-15 Banyu Pharmaceutical Co., Ltd. ピペラジン誘導体
US8772297B2 (en) * 2010-02-17 2014-07-08 Kyoto University TGF-β signal transduction inhibitor
TW201514143A (zh) * 2013-03-20 2015-04-16 Hoffmann La Roche 新穎脲衍生物
US20160068486A1 (en) 2013-04-22 2016-03-10 Reuter Chemische Apparatebau Kg Process for preparing enantiomerically enriched 3-hydroxymethylpiperidine
EP3036219A4 (de) * 2013-06-04 2017-08-23 Temple University Of The Commonwealth System Of Higher Education Neuartige beta-lactame als modulatoren einer glutamataufnahme und verfahren zur verwendung davon
ES2945905T3 (es) * 2014-02-07 2023-07-10 Exithera Pharmaceuticals Inc Compuestos y composiciones terapéuticos
EP3749662A4 (de) 2018-02-07 2021-07-14 Exithera Pharmaceuticals Inc. Therapeutische verbindungen und zusammensetzungen
WO2019185046A1 (zh) * 2018-03-30 2019-10-03 上海美悦生物科技发展有限公司 四元内酰胺类化合物及其药学用途
CN109988098A (zh) * 2019-05-23 2019-07-09 常州工程职业技术学院 一种(r)-n-叔丁氧羰基-3-羟甲基哌啶的合成方法
CN114040908A (zh) * 2019-06-25 2022-02-11 广东东阳光药业有限公司 一种凝血因子XIa抑制剂的晶型及其制备方法
CN114929869A (zh) 2019-11-08 2022-08-19 科亚韦治疗公司 修饰的腺相关病毒载体及将其递送至中枢神经系统
WO2022096681A1 (en) * 2020-11-06 2022-05-12 Coave Therapeutics Lactam-modified adeno-associated virus vectors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175283A (en) * 1990-06-04 1992-12-29 Bristol-Myers Squibb Company Azetidin-2-one derivatives as serine protease inhibitors
US5110812A (en) * 1990-06-04 1992-05-05 Bristol-Myers Squibb Co. Azetidin-2-one derivatives as serine protease inhibitors
US5250677A (en) * 1990-06-04 1993-10-05 Bristol-Myers Squibb Company Azetidin-2-one derivatives as serine protease inhibitors
US5037819A (en) * 1990-06-04 1991-08-06 Bristol-Myers Squibb Company Azetidin-2-one derivatives as serine protease inhibitors
US5747485A (en) * 1995-04-13 1998-05-05 Merck & Co., Inc. Substituted azetidiones as anti-inflammatory and antidegenerative agents
EP0950046B1 (de) * 1996-09-23 2002-04-10 Naeja Pharmaceutical Inc. 3,4-disubstituierte azetidin-2-on-derivate die als cystein-proteinase regulatoren nuetzlich sind

Also Published As

Publication number Publication date
AR018945A1 (es) 2001-12-12
RU2211832C2 (ru) 2003-09-10
DE69928257D1 (de) 2005-12-15
WO1999067215A1 (en) 1999-12-29
EP1089973A1 (de) 2001-04-11
TR200003859T2 (tr) 2001-07-23
CN1202081C (zh) 2005-05-18
AU4695099A (en) 2000-01-10
PL345067A1 (en) 2001-12-03
AU752320B2 (en) 2002-09-12
PE20000729A1 (es) 2000-10-28
KR20010053173A (ko) 2001-06-25
NO20006380L (no) 2000-12-14
NZ507627A (en) 2003-12-19
EP1089973B1 (de) 2005-11-09
EP1089973A4 (de) 2001-12-12
NO20006380D0 (no) 2000-12-14
UY25580A1 (es) 2001-08-27
ES2249017T3 (es) 2006-03-16
ZA200006028B (en) 2002-09-25
ATE309211T1 (de) 2005-11-15
BR9911373A (pt) 2001-09-18
IL140414A0 (en) 2002-02-10
DE69928257T2 (de) 2006-08-03
TW548270B (en) 2003-08-21
HUP0104308A3 (en) 2002-06-28
HUP0104308A2 (hu) 2002-04-29
JP2002518478A (ja) 2002-06-25
CN1307560A (zh) 2001-08-08
CA2336003A1 (en) 1999-12-29

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