ID26031A - Turunan indol yang memiliki suatu aktivitas antiviral - Google Patents
Turunan indol yang memiliki suatu aktivitas antiviralInfo
- Publication number
- ID26031A ID26031A IDW20001898A ID20001898A ID26031A ID 26031 A ID26031 A ID 26031A ID W20001898 A IDW20001898 A ID W20001898A ID 20001898 A ID20001898 A ID 20001898A ID 26031 A ID26031 A ID 26031A
- Authority
- ID
- Indonesia
- Prior art keywords
- indol
- damages
- antiviral activity
- antiviral
- activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/22—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7820398 | 1998-03-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
ID26031A true ID26031A (id) | 2000-11-16 |
Family
ID=13655476
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IDW20001898A ID26031A (id) | 1998-03-26 | 1999-03-26 | Turunan indol yang memiliki suatu aktivitas antiviral |
Country Status (17)
Country | Link |
---|---|
US (3) | US6333323B1 (ru) |
EP (1) | EP1069111A4 (ru) |
JP (1) | JP3794469B2 (ru) |
KR (1) | KR20010041705A (ru) |
CN (1) | CN1142909C (ru) |
AU (1) | AU752005B2 (ru) |
BR (1) | BR9909146A (ru) |
CA (1) | CA2326166A1 (ru) |
HU (1) | HUP0103460A3 (ru) |
ID (1) | ID26031A (ru) |
IL (1) | IL137974A0 (ru) |
NO (1) | NO317423B1 (ru) |
NZ (1) | NZ506435A (ru) |
PL (1) | PL343249A1 (ru) |
RU (1) | RU2217421C2 (ru) |
WO (1) | WO1999050245A1 (ru) |
ZA (1) | ZA200004047B (ru) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6142163A (en) * | 1996-03-29 | 2000-11-07 | Lam Research Corporation | Method and apparatus for pressure control in vacuum processors |
AU752005B2 (en) * | 1998-03-26 | 2002-09-05 | Shionogi & Co., Ltd. | Indole derivatives with antiviral activity |
CA2333707A1 (en) * | 1998-06-03 | 1999-12-09 | Melissa Egbertson | Hiv integrase inhibitors |
JP2002517390A (ja) * | 1998-06-03 | 2002-06-18 | メルク エンド カムパニー インコーポレーテッド | Hivインテグラーゼ阻害薬 |
BR9916583A (pt) | 1998-12-25 | 2001-09-25 | Shionogi & Co | Derivados heteroaromáticos tendo uma atividade inibitória contra integrase de hiv |
US7294481B1 (en) * | 1999-01-05 | 2007-11-13 | Immunex Corporation | Method for producing recombinant proteins |
BR0011246A (pt) * | 1999-06-02 | 2002-03-05 | Shionogi & Co | Processos para o preparo de novos derivados de propenona substituìda |
CA2370500A1 (en) * | 1999-06-25 | 2001-01-04 | Lekhanh O. Tran | 1-(aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof |
US7576198B1 (en) * | 1999-09-02 | 2009-08-18 | Shionogi & Co., Ltd. | Integrase inhibitors containing aromatic heterocycle derivatives |
AP2003002716A0 (en) * | 2000-06-13 | 2003-06-30 | Shionogi & Co | Medicinal compositions containing propenone derivatives. |
AU2001262732A1 (en) * | 2000-06-14 | 2001-12-24 | Shionogi And Co., Ltd. | Inhibitor for enzyme having two divalent metal ions as active centers |
EP1341414B1 (en) * | 2000-11-16 | 2013-01-02 | The Regents of The University of California | Marine actinomycete taxon for drug and fermentation product discovery |
US7067539B2 (en) | 2001-02-08 | 2006-06-27 | Schering Corporation | Cannabinoid receptor ligands |
US7507767B2 (en) | 2001-02-08 | 2009-03-24 | Schering Corporation | Cannabinoid receptor ligands |
JP3616628B2 (ja) | 2001-03-01 | 2005-02-02 | 塩野義製薬株式会社 | Hivインテグラーゼ阻害活性を有する含窒素芳香族複素環化合物 |
JP4338192B2 (ja) | 2001-08-10 | 2009-10-07 | 塩野義製薬株式会社 | 抗ウイルス剤 |
ITMI20012060A1 (it) * | 2001-10-05 | 2003-04-05 | Recordati Chem Pharm | Nuovi eterocilcli n-acilati |
UA77454C2 (en) * | 2001-10-26 | 2006-12-15 | N-substituted hydroxypyrimidinone carboxamide inhibitors of hiv integrase | |
TW200302088A (en) | 2001-11-14 | 2003-08-01 | Schering Corp | Cannabinoid receptor ligands |
WO2003049695A2 (en) * | 2001-12-07 | 2003-06-19 | The Government Of The United States Of America As Represented By The Secretary, Department Of Healthand Human Services | Compounds to treat hiv infection and aids |
US20030236277A1 (en) | 2002-02-14 | 2003-12-25 | Kadow John F. | Indole, azaindole and related heterocyclic pyrrolidine derivatives |
JP2005533809A (ja) | 2002-06-19 | 2005-11-10 | シェーリング コーポレイション | カンナビノイドレセプタアゴニスト |
US7176232B2 (en) | 2002-06-24 | 2007-02-13 | The Regents Of The University Of California | Salinosporamides and methods for use thereof |
US7935704B2 (en) * | 2003-08-01 | 2011-05-03 | Nereus Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
US7919497B2 (en) * | 2002-08-02 | 2011-04-05 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
EP1529044B1 (en) * | 2002-08-02 | 2007-10-03 | Nereus Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
ATE404537T1 (de) | 2002-08-13 | 2008-08-15 | Shionogi & Co | Heterocyclische verbindungen mit hiv-integrase- hemmender wirkung |
AU2003296908A1 (en) * | 2002-09-27 | 2004-05-04 | Nereus Pharmaceuticals, Inc. | Macrocyclic lactams |
TW200505902A (en) | 2003-03-20 | 2005-02-16 | Schering Corp | Cannabinoid receptor ligands |
BRPI0411677A (pt) * | 2003-06-20 | 2006-08-29 | Nereus Pharmaceuticals Inc | métodos de uso de compostos heterocìclicos [3.2.0] e seus análogos |
ZA200600473B (en) * | 2003-06-20 | 2007-04-25 | Univ California | Salinosporamides and methods for use thereof |
CA2552350A1 (en) * | 2004-01-23 | 2005-08-04 | Nereus Pharmaceuticals, Inc. | Bis-indole pyrroles useful as antimicrobials agents |
DE602005023717D1 (de) | 2004-03-10 | 2010-11-04 | Usa | Chinolin-4-one als inhibitoren der retroviralen integrase zur behandlung von hiv, aids und aids-related complex (arc) |
EP2025679A3 (en) | 2004-04-30 | 2009-07-08 | Nereus Pharmaceuticals, Inc. | [3.2.0] Heterocyclic compounds and methods of using the same |
US7579371B2 (en) | 2004-04-30 | 2009-08-25 | Nereus Pharmaceuticals, Inc. | Methods of using [3.2.0] heterocyclic compounds and analogs thereof |
NZ554232A (en) * | 2004-09-17 | 2010-09-30 | Idenix Pharmaceuticals Inc | Phosphoindoles as HIV inhibitors |
US20060100432A1 (en) | 2004-11-09 | 2006-05-11 | Matiskella John D | Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione |
SG157365A1 (en) | 2004-12-03 | 2009-12-29 | Dana Farber Cancer Inst Inc | Compositions and methods for treating neoplastic diseases |
CN1316968C (zh) * | 2005-09-30 | 2007-05-23 | 青岛大学 | 吲哚-2,3-二酮在制备抗病毒或免疫增强剂药物中的应用 |
US7851476B2 (en) | 2005-12-14 | 2010-12-14 | Bristol-Myers Squibb Company | Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-YL)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-C]pyridin-3-YL]-1,2-dioxoethyl]-piperazine |
CN101395134B (zh) | 2006-03-02 | 2011-08-31 | 安斯泰来制药有限公司 | 17β-羟类固醇脱氢酶5型抑制剂 |
CA2645893A1 (en) * | 2006-03-17 | 2007-09-27 | Cipla Limited | Synthesis of 4-[1-(4-cyano phenyl)-(1,2,4-tr1azol-1-yl)methyl] benzonitrile and 4-[1-(1h-1,2,4-triazol-1-yl)methylene benzonitrile intermediate |
NZ572026A (en) | 2006-04-06 | 2011-12-22 | Nereus Pharmaceuticals Inc | Total synthesis of salinosporamide a and analogs thereof |
US7807671B2 (en) | 2006-04-25 | 2010-10-05 | Bristol-Myers Squibb Company | Diketo-piperazine and piperidine derivatives as antiviral agents |
JP2010504978A (ja) * | 2006-09-29 | 2010-02-18 | アイデニクス ファーマシューティカルズ,インコーポレーテッド | Hiv阻害剤としての鏡像異性的に純粋なホスホインドール |
US8129527B2 (en) * | 2006-11-03 | 2012-03-06 | Nereus Pharmacuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
US7824698B2 (en) * | 2007-02-02 | 2010-11-02 | Nereus Pharmaceuticals, Inc. | Lyophilized formulations of Salinosporamide A |
US8394816B2 (en) * | 2007-12-07 | 2013-03-12 | Irene Ghobrial | Methods of using [3.2.0] heterocyclic compounds and analogs thereof in treating Waldenstrom's Macroglobulinemia |
CA2708281A1 (en) | 2007-12-11 | 2009-08-27 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties |
CA2723465A1 (en) * | 2008-05-12 | 2009-11-19 | Nereus Pharmaceuticals, Inc. | Proteasome inhibitors |
WO2013123658A1 (en) | 2012-02-23 | 2013-08-29 | Empire Technology Development Llc | Azobenzene compounds with cholesterol group and their sunscreen compositions |
CN103420894A (zh) * | 2012-05-22 | 2013-12-04 | 中国科学院上海药物研究所 | 丁-2-烯-1,4-二酮类化合物及其制备方法和用途 |
EP3708168A3 (en) | 2014-09-14 | 2020-12-09 | Avanir Pharmaceuticals, Inc. | Combinations of deuterated dextromethorphan and quinidine for the treatment of agitation in dementia |
EP3265091A4 (en) | 2015-03-06 | 2018-08-01 | Beyondspring Pharmaceuticals Inc. | Method of treating a brain tumor |
JP6769982B2 (ja) | 2015-03-06 | 2020-10-14 | ビヨンドスプリング ファーマシューティカルズ,インコーポレイテッド | Ras変異と関連するがんの治療方法 |
SG10202108194XA (en) | 2015-07-13 | 2021-09-29 | Beyondspring Pharmaceuticals Inc | Plinabulin compositions |
MX2018009413A (es) | 2016-02-08 | 2019-05-15 | Beyondspring Pharmaceuticals Inc | Composiciones que contienen tucaresol o sus analogos. |
KR20230018545A (ko) | 2016-06-06 | 2023-02-07 | 비욘드스프링 파마수티컬스, 인코포레이티드. | 호중구감소증을 줄이는 조성물 및 방법 |
US11633393B2 (en) | 2017-01-06 | 2023-04-25 | Beyondspring Pharmaceuticals, Inc. | Tubulin binding compounds and therapeutic use thereof |
SG11201907023UA (en) | 2017-02-01 | 2019-08-27 | Beyondspring Pharmaceuticals Inc | Method of reducing neutropenia |
CN106995400B (zh) * | 2017-04-10 | 2019-08-06 | 湘潭大学 | 一种化合物及其盐及其合成方法 |
CN107226810B (zh) * | 2017-06-16 | 2020-04-28 | 郑州大学 | 吲哚衍生物及其制备方法和其抗流感病毒作用 |
WO2019147615A1 (en) | 2018-01-24 | 2019-08-01 | Beyondspring Pharmaceuticals, Inc. | Composition and method for reducing thrombocytopenia via the administration of plinabulin |
CN109810044B (zh) * | 2019-02-27 | 2022-05-03 | 贵州医科大学 | 一种具有hiv-1整合酶抑制活性的化合物及其制备和应用 |
TW202340187A (zh) * | 2021-12-20 | 2023-10-16 | 加拿大商費爾哈芬製藥公司 | Oxer1拮抗劑及其用途 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4377698A (en) * | 1976-01-22 | 1983-03-22 | Sterling Drug Inc. | 2,4 Bis(2-indolyl-3)-4-oxobutanoic acids |
WO1993005020A1 (en) * | 1991-09-06 | 1993-03-18 | Merck & Co., Inc. | Indoles as inhibitors of hiv reverse transcriptase |
US5475109A (en) | 1994-10-17 | 1995-12-12 | Merck & Co., Inc. | Dioxobutanoic acid derivatives as inhibitors of influenza endonuclease |
DE69622031T2 (de) * | 1995-04-10 | 2002-12-12 | Fujisawa Pharmaceutical Co., Ltd. | INDOLDERIVATE ALS cGMP-PDE INHIBITOREN |
US5858738A (en) * | 1996-11-07 | 1999-01-12 | Merck & Co., Inc. | Ermophilane sesquiterpenoids as HIV intergrase inhibitors |
AU752005B2 (en) * | 1998-03-26 | 2002-09-05 | Shionogi & Co., Ltd. | Indole derivatives with antiviral activity |
JP2002517390A (ja) | 1998-06-03 | 2002-06-18 | メルク エンド カムパニー インコーポレーテッド | Hivインテグラーゼ阻害薬 |
CA2333707A1 (en) | 1998-06-03 | 1999-12-09 | Melissa Egbertson | Hiv integrase inhibitors |
JP2002516858A (ja) | 1998-06-03 | 2002-06-11 | メルク エンド カムパニー インコーポレーテッド | Hivインテグラーゼ阻害薬 |
CA2370500A1 (en) | 1999-06-25 | 2001-01-04 | Lekhanh O. Tran | 1-(aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof |
-
1999
- 1999-03-26 AU AU29581/99A patent/AU752005B2/en not_active Ceased
- 1999-03-26 HU HU0103460A patent/HUP0103460A3/hu unknown
- 1999-03-26 ID IDW20001898A patent/ID26031A/id unknown
- 1999-03-26 JP JP2000541150A patent/JP3794469B2/ja not_active Expired - Fee Related
- 1999-03-26 KR KR1020007009926A patent/KR20010041705A/ko not_active Application Discontinuation
- 1999-03-26 EP EP99910719A patent/EP1069111A4/en not_active Withdrawn
- 1999-03-26 RU RU2000126474/04A patent/RU2217421C2/ru not_active IP Right Cessation
- 1999-03-26 PL PL99343249A patent/PL343249A1/xx unknown
- 1999-03-26 US US09/622,543 patent/US6333323B1/en not_active Expired - Fee Related
- 1999-03-26 NZ NZ506435A patent/NZ506435A/xx unknown
- 1999-03-26 BR BR9909146-1A patent/BR9909146A/pt not_active IP Right Cessation
- 1999-03-26 IL IL13797499A patent/IL137974A0/xx unknown
- 1999-03-26 CN CNB998044180A patent/CN1142909C/zh not_active Expired - Fee Related
- 1999-03-26 WO PCT/JP1999/001547 patent/WO1999050245A1/ja not_active Application Discontinuation
- 1999-03-26 CA CA002326166A patent/CA2326166A1/en not_active Abandoned
-
2000
- 2000-08-08 ZA ZA200004047A patent/ZA200004047B/xx unknown
- 2000-09-25 NO NO20004787A patent/NO317423B1/no not_active IP Right Cessation
-
2001
- 2001-08-15 US US09/929,486 patent/US6506787B2/en not_active Expired - Fee Related
-
2002
- 2002-09-30 US US10/259,903 patent/US6716605B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
RU2217421C2 (ru) | 2003-11-27 |
BR9909146A (pt) | 2000-12-05 |
EP1069111A1 (en) | 2001-01-17 |
JP3794469B2 (ja) | 2006-07-05 |
US20030181499A1 (en) | 2003-09-25 |
HUP0103460A2 (hu) | 2002-01-28 |
NO20004787L (no) | 2000-11-27 |
US6716605B2 (en) | 2004-04-06 |
HUP0103460A3 (en) | 2002-11-28 |
NO20004787D0 (no) | 2000-09-25 |
ZA200004047B (en) | 2001-04-25 |
PL343249A1 (en) | 2001-07-30 |
WO1999050245A1 (fr) | 1999-10-07 |
CN1142909C (zh) | 2004-03-24 |
US6506787B2 (en) | 2003-01-14 |
US20020019434A1 (en) | 2002-02-14 |
AU2958199A (en) | 1999-10-18 |
NO317423B1 (no) | 2004-10-25 |
NZ506435A (en) | 2002-08-28 |
KR20010041705A (ko) | 2001-05-25 |
US6333323B1 (en) | 2001-12-25 |
CN1294580A (zh) | 2001-05-09 |
EP1069111A4 (en) | 2001-06-06 |
IL137974A0 (en) | 2001-10-31 |
AU752005B2 (en) | 2002-09-05 |
CA2326166A1 (en) | 1999-10-07 |
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