ID22490A - Benzamida-benzamida yang disubstitusi secara heterosiklik yang baru dan penggunaannya - Google Patents
Benzamida-benzamida yang disubstitusi secara heterosiklik yang baru dan penggunaannyaInfo
- Publication number
- ID22490A ID22490A IDW990486D ID990486D ID22490A ID 22490 A ID22490 A ID 22490A ID W990486 D IDW990486 D ID W990486D ID 990486 D ID990486 D ID 990486D ID 22490 A ID22490 A ID 22490A
- Authority
- ID
- Indonesia
- Prior art keywords
- heterosiclic
- new
- benzamides substituted
- benzamides
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/62—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
- C07D209/66—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles with oxygen atoms in positions 1 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19650975A DE19650975A1 (de) | 1996-12-09 | 1996-12-09 | Neue heterocyclisch substituierte Benzamide und deren Anwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
ID22490A true ID22490A (id) | 1999-10-21 |
Family
ID=7814035
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IDW990486D ID22490A (id) | 1996-12-09 | 1997-11-28 | Benzamida-benzamida yang disubstitusi secara heterosiklik yang baru dan penggunaannya |
Country Status (24)
Country | Link |
---|---|
US (2) | US6172072B1 (fr) |
EP (1) | EP0946509A1 (fr) |
JP (1) | JP2001505889A (fr) |
KR (1) | KR20000057445A (fr) |
CN (1) | CN1239949A (fr) |
AR (1) | AR010339A1 (fr) |
AU (1) | AU742732B2 (fr) |
BG (1) | BG63388B1 (fr) |
BR (1) | BR9713884A (fr) |
CA (1) | CA2273988A1 (fr) |
CO (1) | CO4910161A1 (fr) |
CZ (1) | CZ292391B6 (fr) |
DE (1) | DE19650975A1 (fr) |
HR (1) | HRP970671A2 (fr) |
HU (1) | HUP0000496A3 (fr) |
ID (1) | ID22490A (fr) |
IL (1) | IL129358A0 (fr) |
NO (1) | NO992770D0 (fr) |
NZ (1) | NZ335066A (fr) |
SK (1) | SK56699A3 (fr) |
TR (1) | TR199901282T2 (fr) |
TW (1) | TW420666B (fr) |
WO (1) | WO1998025899A1 (fr) |
ZA (1) | ZA9710979B (fr) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU3818799A (en) * | 1998-04-20 | 1999-11-08 | Basf Aktiengesellschaft | Novel heterocyclically substituted amides with cysteine protease-inhibiting effect |
FR2800737B1 (fr) * | 1999-11-05 | 2006-06-30 | Sod Conseils Rech Applic | Nouveaux composes heterocycliques et leur application a titre de medicaments |
PL200167B1 (pl) * | 1999-11-05 | 2008-12-31 | Sod Conseils Rech Applic | Związki heterocykliczne o aktywności hamowania kalpain i/lub pułapkowania ROS, ich zastosowanie i kompozycje farmaceutyczne je zawierające oraz związki pośrednie |
GB0031302D0 (en) * | 2000-12-21 | 2001-01-31 | Glaxo Group Ltd | Napthalene derivatives |
KR100962972B1 (ko) | 2002-07-26 | 2010-06-09 | 주식회사유한양행 | 1-페닐피페리딘-3-온 유도체 및 그의 제조방법 |
CA2505098A1 (fr) | 2002-11-12 | 2004-05-27 | Merck & Co., Inc. | Inhibiteurs de beta-secretase phenylcarboxamide utilises dans le traitement de la maladie d'alzheimer |
CA2536313A1 (fr) * | 2003-08-22 | 2005-03-03 | Takeda Pharmaceutical Company Limited | Derive de pyrimidine fusionne et utilisation associee |
US7320992B2 (en) * | 2003-08-25 | 2008-01-22 | Amgen Inc. | Substituted 2,3-dihydro-1h-isoindol-1-one derivatives and methods of use |
FR2863268B1 (fr) * | 2003-12-09 | 2006-02-24 | Sod Conseils Rech Applic | Nouveaux derives du 2-hydroxytetrahydrofuranne et leur application a titre de medicaments |
BRPI0418026A (pt) * | 2003-12-22 | 2007-04-17 | Ajinomoto Kk | derivados de fenilalanina ou sais farmaceuticamente aceitáveis destes, composição farmacêutica, antagonista de alfa4 integrina, e, agente terapêutico ou agente preventivo para doenças |
GB0416730D0 (en) | 2004-07-27 | 2004-09-01 | Novartis Ag | Organic compounds |
US20070010537A1 (en) * | 2004-08-20 | 2007-01-11 | Kazumasa Hamamura | Fused pyramidine derivative and use thereof |
GB0507298D0 (en) | 2005-04-11 | 2005-05-18 | Novartis Ag | Organic compounds |
US7834023B2 (en) * | 2006-09-20 | 2010-11-16 | Portola Pharmaceuticals, Inc. | Substituted dihydroquinazolines as platelet ADP receptor inhibitors |
JP5295976B2 (ja) | 2006-12-29 | 2013-09-18 | アボット ゲーエムベーハー ウント カンパニー カーゲー | カルボキサミド化合物およびカルパイン阻害剤としてのこれらの使用 |
ES2576643T3 (es) | 2007-03-09 | 2016-07-08 | Second Genome, Inc. | Compuestos de bicicloheteroarilo como moduladores de P2X7 y usos de los mismos |
TWI453019B (zh) | 2007-12-28 | 2014-09-21 | Abbvie Deutschland | 甲醯胺化合物 |
TWI519530B (zh) | 2009-02-20 | 2016-02-01 | 艾伯維德國有限及兩合公司 | 羰醯胺化合物及其作為鈣蛋白酶(calpain)抑制劑之用途 |
US8236798B2 (en) | 2009-05-07 | 2012-08-07 | Abbott Gmbh & Co. Kg | Carboxamide compounds and their use as calpain inhibitors |
US9051304B2 (en) | 2009-12-22 | 2015-06-09 | AbbVie Deutschland GmbH & Co. KG | Carboxamide compounds and their use as calpain inhibitors V |
US8598211B2 (en) | 2009-12-22 | 2013-12-03 | Abbvie Inc. | Carboxamide compounds and their use as calpain inhibitors IV |
CN102939126B (zh) | 2010-04-30 | 2015-09-16 | 雅培心脏血管系统股份有限公司 | 呈现迅速膨胀和收缩的改进型球囊导管 |
WO2012076639A1 (fr) | 2010-12-09 | 2012-06-14 | Abbott Gmbh & Co. Kg | Composés de carboxamide et leur utilisation comme inhibiteurs v de la calpaïne |
RU2014144285A (ru) | 2012-04-03 | 2016-05-27 | Эббви Дойчланд Гмбх Унд Ко. Кг | Карбоксамидные соединения и их применение в качестве ингибиторов кальпаина v |
EP3426674A4 (fr) | 2016-03-09 | 2019-08-14 | Blade Therapeutics, Inc. | Composés céto-amides cycliques utilisés en tant que modulateurs de la calpaïne, et leurs procédés de production et d'utilisation |
AU2017292646A1 (en) | 2016-07-05 | 2019-02-07 | Blade Therapeutics, Inc. | Calpain modulators and therapeutic uses thereof |
CA3038331A1 (fr) | 2016-09-28 | 2018-04-05 | Blade Therapeutics, Inc. | Modulateurs de calpain et leurs utilisations therapeutiques |
WO2020113094A1 (fr) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Composés pyrrole et pyrazole et leurs procédés d'utilisation |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8524663D0 (en) * | 1985-10-07 | 1985-11-13 | Fujisawa Pharmaceutical Co | Quinazoline derivatives |
DE3717828A1 (de) * | 1987-05-27 | 1988-12-15 | Hoechst Ag | Siliziumhaltige benzoesaeurederivate, verfahren zu ihrer herstellung sowie ihre verwendung im pflanzenschutz |
DE4000204A1 (de) | 1990-01-05 | 1991-07-11 | Steag Ag | Vorrichtung zum dosierten austragen von schuettfaehigem feststoff |
EP0473551A1 (fr) * | 1990-08-31 | 1992-03-04 | Ciba-Geigy Ag | Dérivés de 3-arylaracile, procédé pour leur préparation et herbicides les contenant |
DE69113284T2 (de) | 1990-12-28 | 1996-02-22 | Kyowa Hakko Kogyo Co., Ltd., Tokio/Tokyo | Chinolinderivat. |
WO1992011850A2 (fr) | 1990-12-28 | 1992-07-23 | Cortex Pharmaceuticals, Inc. | Utilisation d'inhibiteurs de la calpaine dans l'inhibition et le traitement de la neurodegenerescence |
CA2071621C (fr) * | 1991-06-19 | 1996-08-06 | Ahihiko Hosoda | Derives d'aldehyde |
JPH09500087A (ja) | 1992-06-24 | 1997-01-07 | コーテックス ファーマシューティカルズ インコーポレイテッド | カルパイン活性の増大に関連した健康障害の抑制及び処置におけるカルパイン阻害剤の使用法 |
US5541290A (en) | 1993-06-24 | 1996-07-30 | Harbeson; Scott L. | Optically pure calpain inhibitor compounds |
-
1996
- 1996-12-09 DE DE19650975A patent/DE19650975A1/de not_active Withdrawn
-
1997
- 1997-11-28 CN CN97180437A patent/CN1239949A/zh active Pending
- 1997-11-28 CZ CZ19991743A patent/CZ292391B6/cs not_active IP Right Cessation
- 1997-11-28 WO PCT/EP1997/006653 patent/WO1998025899A1/fr active IP Right Grant
- 1997-11-28 IL IL12935897A patent/IL129358A0/xx unknown
- 1997-11-28 KR KR1019990705071A patent/KR20000057445A/ko not_active Application Discontinuation
- 1997-11-28 HU HU0000496A patent/HUP0000496A3/hu unknown
- 1997-11-28 AU AU55580/98A patent/AU742732B2/en not_active Ceased
- 1997-11-28 NZ NZ335066A patent/NZ335066A/xx unknown
- 1997-11-28 CA CA002273988A patent/CA2273988A1/fr not_active Abandoned
- 1997-11-28 SK SK566-99A patent/SK56699A3/sk unknown
- 1997-11-28 ID IDW990486D patent/ID22490A/id unknown
- 1997-11-28 JP JP52615598A patent/JP2001505889A/ja active Pending
- 1997-11-28 US US09/308,350 patent/US6172072B1/en not_active Expired - Fee Related
- 1997-11-28 BR BR9713884-3A patent/BR9713884A/pt not_active IP Right Cessation
- 1997-11-28 EP EP97952007A patent/EP0946509A1/fr not_active Withdrawn
- 1997-11-28 TR TR1999/01282T patent/TR199901282T2/xx unknown
- 1997-12-08 ZA ZA9710979A patent/ZA9710979B/xx unknown
- 1997-12-08 HR HR19650975.0A patent/HRP970671A2/hr not_active Application Discontinuation
- 1997-12-08 TW TW086118462A patent/TW420666B/zh active
- 1997-12-09 AR ARP970105766A patent/AR010339A1/es not_active Application Discontinuation
- 1997-12-09 CO CO97071820A patent/CO4910161A1/es unknown
-
1999
- 1999-05-12 BG BG103399A patent/BG63388B1/bg unknown
- 1999-06-08 NO NO992770A patent/NO992770D0/no unknown
-
2000
- 2000-09-21 US US09/666,304 patent/US6436949B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CZ292391B6 (cs) | 2003-09-17 |
HRP970671A2 (en) | 1998-10-31 |
NO992770L (no) | 1999-06-08 |
WO1998025899A1 (fr) | 1998-06-18 |
BR9713884A (pt) | 2000-02-29 |
ZA9710979B (en) | 1999-06-18 |
BG103399A (en) | 2000-01-31 |
NO992770D0 (no) | 1999-06-08 |
SK56699A3 (en) | 1999-10-08 |
TR199901282T2 (xx) | 1999-10-21 |
AU742732B2 (en) | 2002-01-10 |
CO4910161A1 (es) | 2000-04-24 |
HUP0000496A3 (en) | 2002-11-28 |
EP0946509A1 (fr) | 1999-10-06 |
BG63388B1 (bg) | 2001-12-29 |
KR20000057445A (ko) | 2000-09-15 |
IL129358A0 (en) | 2000-02-17 |
DE19650975A1 (de) | 1998-06-10 |
CZ174399A3 (cs) | 1999-08-11 |
CA2273988A1 (fr) | 1998-06-18 |
US6436949B1 (en) | 2002-08-20 |
AR010339A1 (es) | 2000-06-07 |
CN1239949A (zh) | 1999-12-29 |
JP2001505889A (ja) | 2001-05-08 |
NZ335066A (en) | 2000-03-27 |
AU5558098A (en) | 1998-07-03 |
US6172072B1 (en) | 2001-01-09 |
TW420666B (en) | 2001-02-01 |
HUP0000496A2 (hu) | 2000-09-28 |
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