HUT47560A - Process for production of enol-silil-esthers - Google Patents

Process for production of enol-silil-esthers

Info

Publication number
HUT47560A
HUT47560A HU864865A HU486586A HUT47560A HU T47560 A HUT47560 A HU T47560A HU 864865 A HU864865 A HU 864865A HU 486586 A HU486586 A HU 486586A HU T47560 A HUT47560 A HU T47560A
Authority
HU
Hungary
Prior art keywords
silil
esthers
enol
production
intermediates
Prior art date
Application number
HU864865A
Other languages
English (en)
Hungarian (hu)
Inventor
Takushi Kaneko
Henry S Wong
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of HUT47560A publication Critical patent/HUT47560A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Furan Compounds (AREA)
HU864865A 1985-12-05 1986-12-04 Process for production of enol-silil-esthers HUT47560A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/805,484 US4734512A (en) 1985-12-05 1985-12-05 Intermediates for the production of podophyllotoxin and related compounds and processes for the preparation and use thereof

Publications (1)

Publication Number Publication Date
HUT47560A true HUT47560A (en) 1989-03-28

Family

ID=25191684

Family Applications (5)

Application Number Title Priority Date Filing Date
HU864865A HUT47560A (en) 1985-12-05 1986-12-04 Process for production of enol-silil-esthers
HU865028A HU198938B (en) 1985-12-05 1986-12-04 Process for producing podophyllotoxin and podophyllotoxin derivatives
HU864864A HU198940B (en) 1985-12-05 1986-12-04 Process for producing neopodophyllotoxin derivatives
HU884863A HU198939B (en) 1985-12-05 1986-12-04 Process for producing neopodophyllotoxin benzylether derivatives
HU864862D HU198465B (en) 1985-12-05 1986-12-04 Process for producing 3-/benzyloxymethyl/-aryl-tetralone derivatives

Family Applications After (4)

Application Number Title Priority Date Filing Date
HU865028A HU198938B (en) 1985-12-05 1986-12-04 Process for producing podophyllotoxin and podophyllotoxin derivatives
HU864864A HU198940B (en) 1985-12-05 1986-12-04 Process for producing neopodophyllotoxin derivatives
HU884863A HU198939B (en) 1985-12-05 1986-12-04 Process for producing neopodophyllotoxin benzylether derivatives
HU864862D HU198465B (en) 1985-12-05 1986-12-04 Process for producing 3-/benzyloxymethyl/-aryl-tetralone derivatives

Country Status (13)

Country Link
US (2) US4734512A (enrdf_load_stackoverflow)
EP (1) EP0224938B1 (enrdf_load_stackoverflow)
JP (1) JPS62145093A (enrdf_load_stackoverflow)
KR (1) KR900004129B1 (enrdf_load_stackoverflow)
AT (1) ATE77380T1 (enrdf_load_stackoverflow)
AU (2) AU599937B2 (enrdf_load_stackoverflow)
CA (4) CA1318321C (enrdf_load_stackoverflow)
DE (1) DE3685727T2 (enrdf_load_stackoverflow)
ES (1) ES2042488T3 (enrdf_load_stackoverflow)
GR (1) GR3005053T3 (enrdf_load_stackoverflow)
HU (5) HUT47560A (enrdf_load_stackoverflow)
IL (3) IL80853A (enrdf_load_stackoverflow)
ZA (1) ZA869184B (enrdf_load_stackoverflow)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011948A (en) * 1985-04-12 1991-04-30 Bristol-Myers Company Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
US4644072A (en) * 1985-04-12 1987-02-17 Bristol-Myers Company Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
US4734512A (en) * 1985-12-05 1988-03-29 Bristol-Myers Company Intermediates for the production of podophyllotoxin and related compounds and processes for the preparation and use thereof
JPS6393796A (ja) * 1986-10-09 1988-04-25 Shin Etsu Chem Co Ltd ペプチド合成の脱保護基用薬剤
GB9422946D0 (en) * 1994-11-14 1995-01-04 Univ Salamanca Antineoplastic cyclolignan derivatives
BRPI0515573A (pt) 2004-09-22 2008-07-29 Nippon Kayaku Kk copolìmero por blocos, preparação de micela e agente anticáncer contendo a mesma como o ingrediente ativo
JP5249016B2 (ja) 2006-03-28 2013-07-31 日本化薬株式会社 タキサン類の高分子結合体
AU2007252678A1 (en) * 2006-05-18 2007-11-29 Nippon Kayaku Kabushiki Kaisha Polymer conjugate of podophyllotoxin
WO2008041610A1 (fr) * 2006-10-03 2008-04-10 Nippon Kayaku Kabushiki Kaisha Mélange d'un dérivé de résorcinol avec un polymère
WO2008056596A1 (en) 2006-11-06 2008-05-15 Nippon Kayaku Kabushiki Kaisha Polymeric derivative of nucleic acid metabolic antagonist
WO2008056654A1 (en) 2006-11-08 2008-05-15 Nippon Kayaku Kabushiki Kaisha Polymeric derivative of nucleic acid metabolic antagonist
CN101808651B (zh) * 2007-09-28 2013-03-27 日本化药株式会社 类固醇类的高分子结合物
US8920788B2 (en) * 2008-03-18 2014-12-30 Nippon Kayaku Kabushiki Kaisha High-molecular weight conjugate of physiologically active substances
US9149540B2 (en) 2008-05-08 2015-10-06 Nippon Kayaku Kabushiki Kaisha Polymer conjugate of folic acid or folic acid derivative
WO2010131675A1 (ja) 2009-05-15 2010-11-18 日本化薬株式会社 水酸基を有する生理活性物質の高分子結合体
WO2012067138A1 (ja) 2010-11-17 2012-05-24 日本化薬株式会社 新規なシチジン系代謝拮抗剤の高分子誘導体
AU2012305405B2 (en) 2011-09-11 2016-01-14 Nippon Kayaku Kabushiki Kaisha Method for manufacturing block copolymer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4294763A (en) * 1980-03-05 1981-10-13 University Of Rochester Intermediates for the production of picropodophyllin and related compounds and processes for the preparation and use thereof
US4391982A (en) * 1980-03-05 1983-07-05 The University Of Rochester Intermediates for the production of picropodophyllin and related compounds and processes for the preparation and use thereof
US4644072A (en) * 1985-04-12 1987-02-17 Bristol-Myers Company Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
US4734512A (en) * 1985-12-05 1988-03-29 Bristol-Myers Company Intermediates for the production of podophyllotoxin and related compounds and processes for the preparation and use thereof

Also Published As

Publication number Publication date
ES2042488T3 (es) 1993-12-16
GR3005053T3 (enrdf_load_stackoverflow) 1993-05-24
AU631216B2 (en) 1992-11-19
HUT48888A (en) 1989-07-28
HUT47559A (en) 1989-03-28
JPS62145093A (ja) 1987-06-29
HUT48878A (en) 1989-07-28
IL93999A (en) 1991-09-16
IL94000A (en) 1991-09-16
HUT47114A (en) 1989-01-30
CA1321596C (en) 1993-08-24
ZA869184B (en) 1987-07-29
CA1318321C (en) 1993-05-25
EP0224938B1 (en) 1992-06-17
HU198465B (en) 1989-10-30
DE3685727D1 (de) 1992-07-23
US4734512A (en) 1988-03-29
IL80853A (en) 1991-09-16
ATE77380T1 (de) 1992-07-15
IL93999A0 (en) 1991-01-31
EP0224938A2 (en) 1987-06-10
US4845248A (en) 1989-07-04
CA1321595C (en) 1993-08-24
EP0224938A3 (en) 1989-11-02
CA1321597C (en) 1993-08-24
KR900004129B1 (ko) 1990-06-16
HU198939B (en) 1989-12-28
AU5715190A (en) 1990-10-04
AU599937B2 (en) 1990-08-02
HU198940B (en) 1989-12-28
KR870006032A (ko) 1987-07-08
AU6587086A (en) 1987-06-11
DE3685727T2 (de) 1993-01-21
HU198938B (en) 1989-12-28
IL94000A0 (en) 1991-01-31

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee