HUP9904547A3 - Benzoxazole derivative with an affinity to binding sites of amino acid receptors and pharmaceutical compositions containing the same - Google Patents

Benzoxazole derivative with an affinity to binding sites of amino acid receptors and pharmaceutical compositions containing the same

Info

Publication number
HUP9904547A3
HUP9904547A3 HU9904547A HUP9904547A HUP9904547A3 HU P9904547 A3 HUP9904547 A3 HU P9904547A3 HU 9904547 A HU9904547 A HU 9904547A HU P9904547 A HUP9904547 A HU P9904547A HU P9904547 A3 HUP9904547 A3 HU P9904547A3
Authority
HU
Hungary
Prior art keywords
affinity
amino acid
pharmaceutical compositions
same
compositions containing
Prior art date
Application number
HU9904547A
Other languages
English (en)
Hungarian (hu)
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of HUP9904547A2 publication Critical patent/HUP9904547A2/hu
Publication of HUP9904547A3 publication Critical patent/HUP9904547A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU9904547A 1996-10-30 1997-10-10 Benzoxazole derivative with an affinity to binding sites of amino acid receptors and pharmaceutical compositions containing the same HUP9904547A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19643790A DE19643790A1 (de) 1996-10-30 1996-10-30 Benzoxazol-Derivat

Publications (2)

Publication Number Publication Date
HUP9904547A2 HUP9904547A2 (hu) 2000-12-28
HUP9904547A3 true HUP9904547A3 (en) 2001-01-29

Family

ID=7809592

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9904547A HUP9904547A3 (en) 1996-10-30 1997-10-10 Benzoxazole derivative with an affinity to binding sites of amino acid receptors and pharmaceutical compositions containing the same

Country Status (16)

Country Link
EP (1) EP0938485A1 (ko)
JP (1) JP2001502713A (ko)
KR (1) KR20000052876A (ko)
CN (1) CN1235604A (ko)
AR (1) AR008512A1 (ko)
AU (1) AU4946597A (ko)
BR (1) BR9712577A (ko)
CA (1) CA2270359A1 (ko)
CZ (1) CZ147999A3 (ko)
DE (1) DE19643790A1 (ko)
HU (1) HUP9904547A3 (ko)
NO (1) NO992063L (ko)
PL (1) PL332771A1 (ko)
SK (1) SK53699A3 (ko)
WO (1) WO1998018793A1 (ko)
ZA (1) ZA979725B (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9725541D0 (en) * 1997-12-02 1998-02-04 Pharmacia & Upjohn Spa Amino-benzothiazole derivatives
DE19812331A1 (de) 1998-03-20 1999-09-23 Merck Patent Gmbh Piperidinderivate
PE20000728A1 (es) 1998-06-26 2000-08-21 Cocensys Inc Heterociclos 4-bencil piperidina alquilsulfoxido y su uso como antagonistas receptores subtipo-selectivo nmda
US6476041B1 (en) 1999-10-29 2002-11-05 Merck & Co., Inc. 1,4 substituted piperidinyl NMDA/NR2B antagonists
EP1674087A1 (en) 2000-10-02 2006-06-28 Pfizer Products Inc. Prophylactic use of n-methyl-d-aspartate (NMDA) antagonists
DE10120159A1 (de) * 2001-04-25 2002-10-31 Merck Patent Gmbh NMDA-Antagonisten und NMDA-Agonisten zur Behandlung von Suchterkrankungen
EP1409477B1 (en) 2001-07-24 2008-09-17 Richter Gedeon NYRT Piperidine derivatives as nmda receptor antagonists
DE102007047737A1 (de) * 2007-10-05 2009-04-30 Merck Patent Gmbh Piperidin- und Piperazinderivate
DE102009049211A1 (de) 2009-10-13 2011-04-28 Merck Patent Gmbh Sulfoxide
MX2014004469A (es) 2011-11-22 2014-08-01 Univ California Metodos y composiciones para tratar inflamacion y lesion isquemica.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2128629T3 (es) * 1994-10-31 1999-05-16 Merck Patent Gmbh Derivados de bencilpiperidina con afinidad elevada a puntos de enlace de receptores de aminoacidos.

Also Published As

Publication number Publication date
NO992063D0 (no) 1999-04-29
HUP9904547A2 (hu) 2000-12-28
EP0938485A1 (de) 1999-09-01
AR008512A1 (es) 2000-01-19
NO992063L (no) 1999-04-29
AU4946597A (en) 1998-05-22
WO1998018793A1 (de) 1998-05-07
JP2001502713A (ja) 2001-02-27
PL332771A1 (en) 1999-10-11
CA2270359A1 (en) 1998-05-07
SK53699A3 (en) 2000-03-13
BR9712577A (pt) 1999-10-19
KR20000052876A (ko) 2000-08-25
ZA979725B (en) 1998-05-22
DE19643790A1 (de) 1998-05-07
CZ147999A3 (cs) 1999-08-11
CN1235604A (zh) 1999-11-17

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