HUP9904325A2 - Eljárás johexol előállítására - Google Patents

Eljárás johexol előállítására

Info

Publication number
HUP9904325A2
HUP9904325A2 HU9904325A HUP9904325A HUP9904325A2 HU P9904325 A2 HUP9904325 A2 HU P9904325A2 HU 9904325 A HU9904325 A HU 9904325A HU P9904325 A HUP9904325 A HU P9904325A HU P9904325 A2 HUP9904325 A2 HU P9904325A2
Authority
HU
Hungary
Prior art keywords
hexol
solvent
johexol
manufacture
raw
Prior art date
Application number
HU9904325A
Other languages
English (en)
Inventor
Odd Einar Ingvoldstad
Dick Malthe-Sorenssen
Espen Myrbráten
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of HUP9904325A2 publication Critical patent/HUP9904325A2/hu
Publication of HUP9904325A3 publication Critical patent/HUP9904325A3/hu
Publication of HU229253B1 publication Critical patent/HU229253B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Saccharide Compounds (AREA)

Abstract

A találmány szerinti eljárás nyers jőhexől tisztítására szőlgál,amelynek sőrán nyers jőhexőlt egy első őldószerből szilárd alakbanelválasztanak, és a szilárd jőhexőlt egy tővábbi őldószerrel mősvajavítőtt tisztaságú jőhexőlt kapnak, ahől első őldószerként (93 : 7) -(85 : 15) térfőgatarányú izőprőpanől/2-metőxi-etanől elegyet, tővábbiőldószerként izőprőpanőlt alkalmaznak. ŕ
HU9904325A 1996-08-29 1997-08-29 Process for johexol manufacture HU229253B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9618056.7A GB9618056D0 (en) 1996-08-29 1996-08-29 Process
PCT/GB1997/002332 WO1998008804A1 (en) 1996-08-29 1997-08-29 Process for iohexol manufacture

Publications (3)

Publication Number Publication Date
HUP9904325A2 true HUP9904325A2 (hu) 2000-04-28
HUP9904325A3 HUP9904325A3 (en) 2000-06-28
HU229253B1 HU229253B1 (en) 2013-10-28

Family

ID=10799120

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9904325A HU229253B1 (en) 1996-08-29 1997-08-29 Process for johexol manufacture

Country Status (26)

Country Link
US (2) US5948940A (hu)
EP (1) EP0925275B1 (hu)
JP (1) JP3780002B2 (hu)
KR (1) KR100517588B1 (hu)
CN (1) CN1120148C (hu)
AT (1) ATE210631T1 (hu)
AU (1) AU723184B2 (hu)
BG (1) BG63663B1 (hu)
BR (1) BR9711381A (hu)
CA (1) CA2265047A1 (hu)
CZ (1) CZ295058B6 (hu)
DE (1) DE69709127T2 (hu)
EE (1) EE9900082A (hu)
ES (1) ES2173476T3 (hu)
GB (1) GB9618056D0 (hu)
HK (1) HK1020722A1 (hu)
HU (1) HU229253B1 (hu)
IL (1) IL128715A (hu)
IN (1) IN186429B (hu)
NO (1) NO322795B1 (hu)
NZ (1) NZ334817A (hu)
PL (1) PL190151B1 (hu)
PT (1) PT925275E (hu)
SK (1) SK26499A3 (hu)
TR (1) TR199900405T2 (hu)
WO (1) WO1998008804A1 (hu)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618056D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
US6262303B1 (en) * 1998-05-08 2001-07-17 Dibra S.P.A. Process for the preparation of S-N,N′-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)-amino]-2,4,6-triiodo-1,3-benzenedicarboxamide
ITMI20010773A1 (it) * 2001-04-11 2002-10-11 Chemi Spa Processo per la produzione di ioexolo ad elevata purezza
TWI288654B (en) * 2001-05-17 2007-10-21 Ind Tech Res Inst Process for the purification of water-soluble non-ionic contrast agents
NO20033058D0 (no) * 2003-07-03 2003-07-03 Amersham Health As Prosess
NO20053687D0 (no) * 2005-07-29 2005-07-29 Amersham Health As Crystallisation Process.
NO20053676D0 (no) 2005-07-29 2005-07-29 Amersham Health As Crystallisation Process
PT103391B (pt) * 2005-11-24 2008-10-30 Hovione Farmaciencia S A Processo para fabrico de lohexol
JP2011509943A (ja) 2008-01-14 2011-03-31 マリンクロッド・インコーポレイテッド イオシメノールを調製するためのプロセス
CN106103407B (zh) * 2014-03-04 2020-10-16 大塚制药株式会社 碘海醇粉末及其使用方法
CN110054569B (zh) * 2019-05-17 2022-05-17 浙江海洲制药有限公司 一种制备碘海醇的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1548594A (en) * 1922-05-27 1925-08-04 Helios Machine Company Motion-converting mechanism
CH608189A5 (hu) * 1974-12-13 1978-12-29 Savac Ag
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
IT1207226B (it) * 1979-08-09 1989-05-17 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
DE3363423D1 (en) * 1982-10-01 1986-06-12 Nyegaard & Co As X-ray contrast agents
LU88639I2 (fr) * 1982-11-08 1996-02-01 Nycomed Imaging S A Agents de contraste pour rayons x
IL94718A (en) * 1989-07-05 1994-10-21 Schering Ag Non-ionic carboxamide contrast agent and method of preparation
US5527926A (en) * 1990-11-26 1996-06-18 Bracco International B.V. Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures
US5371278A (en) * 1994-03-25 1994-12-06 Mallinckrodt Medical Pmc Synthesis of ioversol using a minimal excess of acetoxyacetylchloride
US5624957A (en) * 1995-06-06 1997-04-29 Bristol-Myers Squibb Company Rary-specific retinobenzoic acid derivatives
GB9618056D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
GB9618055D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process

Also Published As

Publication number Publication date
DE69709127D1 (de) 2002-01-24
PL190151B1 (pl) 2005-11-30
PT925275E (pt) 2002-05-31
IL128715A (en) 2002-08-14
NO322795B1 (no) 2006-12-11
HUP9904325A3 (en) 2000-06-28
ES2173476T3 (es) 2002-10-16
CN1120148C (zh) 2003-09-03
CZ66999A3 (cs) 1999-08-11
US6153796A (en) 2000-11-28
AU723184B2 (en) 2000-08-17
GB9618056D0 (en) 1996-10-09
WO1998008804A1 (en) 1998-03-05
CA2265047A1 (en) 1998-03-05
US5948940A (en) 1999-09-07
KR20000035945A (ko) 2000-06-26
BG63663B1 (bg) 2002-08-30
EE9900082A (et) 1999-10-15
HU229253B1 (en) 2013-10-28
ATE210631T1 (de) 2001-12-15
KR100517588B1 (ko) 2005-09-29
EP0925275B1 (en) 2001-12-12
JP2000517312A (ja) 2000-12-26
HK1020722A1 (en) 2000-05-19
BG103289A (en) 2000-01-31
NO990889D0 (no) 1999-02-25
JP3780002B2 (ja) 2006-05-31
EP0925275A1 (en) 1999-06-30
NZ334817A (en) 2000-09-29
AU4123697A (en) 1998-03-19
CZ295058B6 (cs) 2005-05-18
BR9711381A (pt) 1999-08-17
PL331706A1 (en) 1999-08-02
CN1228763A (zh) 1999-09-15
SK26499A3 (en) 1999-08-06
IL128715A0 (en) 2000-01-31
TR199900405T2 (xx) 1999-06-21
IN186429B (hu) 2001-09-01
DE69709127T2 (de) 2002-08-14
NO990889L (no) 1999-02-25

Similar Documents

Publication Publication Date Title
AU585131B2 (en) New aryl-substituted (N-piperidinyl)methyl- and (N-piperazinyl)methylazoles having antipsychotic properties
AU2002220715A1 (en) Indolsulfonyl compounds useful in the treatment of cns disorders
CA2284468A1 (en) Anti-inflammatory compounds
BG103664A (en) Pharmaceutical forms containing ammoxycillin and clavulanate
IL99525A0 (en) Fused ring analogs of nitrogen containing nonaromatic heterocycles
HUP9904325A2 (hu) Eljárás johexol előállítására
DE69631733D1 (de) Siliciumnitridkeramik, Zusammensetzung auf Siliciumbasis zur Herstellung davon und Verfahren zur Herstellung dieser
CA2248006A1 (en) Activated linkers and methods for making and purifying the same
NO971645D0 (no) Fremgangsmåte for fremstilling av derivater av 4a,5,9,10,11,12,-heksahydro-6H-benzofuro(3a,3,2-ef)(2)-benzacepin
GB9300763D0 (en) Chemical compound
CA2241787A1 (en) Substituted aza- and diazacycloheptane and cyclooctane compounds and their use
GR3036813T3 (en) Novel n-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1h-benzo[b][1,4]diazepin-3-yl)-acetamides
AU7219987A (en) Process and composition for the removal of hydrogen sulfide from gaseous streams
AU2714197A (en) Process for the purification of gases containing hydrogen sulphide
AU8974298A (en) 1,4,7,10-tetraazabicyclo{8.2.2}tetradecan-2-one, a process for the preparation thereof and the use thereof for the preparation of tetraazamacrocycles
CA2296466A1 (en) Alatrofloxacin parenteral compositions
CA2286192A1 (en) Use of alcohols as additives for plaster and/or mortar
DE59605545D1 (de) Alkoholhaltige instant-getränkemischung, ihre herstellung und verwendung
EP0273310A3 (en) 5-aryl-3h-1,2,4-triazol-3-ones and their use as anticonvulsants
FR2689518B1 (fr) Microorganismes, procédé de préparation et utilisation.
WO2000006575A3 (en) Azabicyclic compounds
UA37217C2 (uk) Аналоги 15-дезоксиспергуаліну, спосіб їх одержання, фармацевтична композиція та проміжні сполуки
DE69401994T2 (de) Verfahren zur Herstellung von Siliciumnitridpulver hohem Alpha-Gehalt
DE69926223D1 (de) Verfahren zur herstellung von zwischenprodukten
DE59702127D1 (de) Verfahren zur Herstellung poröser Keramik der Zusammensetzung Pb(ZrxTi1-x)O3

Legal Events

Date Code Title Description
HC9A Change of name, address

Owner name: GE HEALTHCARE AS, NO

Free format text: FORMER OWNER(S): AMERSHAM HEALTH AS, NO; NYCOMED IMAGING AS, NO