PT925275E - Processo para o fabrico de iohexol - Google Patents

Processo para o fabrico de iohexol

Info

Publication number
PT925275E
PT925275E PT97939000T PT97939000T PT925275E PT 925275 E PT925275 E PT 925275E PT 97939000 T PT97939000 T PT 97939000T PT 97939000 T PT97939000 T PT 97939000T PT 925275 E PT925275 E PT 925275E
Authority
PT
Portugal
Prior art keywords
iohexol
manufacture
triiodophthalamide
dihydroxypropyl
acetamido
Prior art date
Application number
PT97939000T
Other languages
English (en)
Inventor
Odd Einar Ingvoldstad
Dick Malthe-Sorenssen
Espen Myrbraten
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of PT925275E publication Critical patent/PT925275E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Saccharide Compounds (AREA)
PT97939000T 1996-08-29 1997-08-29 Processo para o fabrico de iohexol PT925275E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9618056.7A GB9618056D0 (en) 1996-08-29 1996-08-29 Process

Publications (1)

Publication Number Publication Date
PT925275E true PT925275E (pt) 2002-05-31

Family

ID=10799120

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97939000T PT925275E (pt) 1996-08-29 1997-08-29 Processo para o fabrico de iohexol

Country Status (26)

Country Link
US (2) US5948940A (pt)
EP (1) EP0925275B1 (pt)
JP (1) JP3780002B2 (pt)
KR (1) KR100517588B1 (pt)
CN (1) CN1120148C (pt)
AT (1) ATE210631T1 (pt)
AU (1) AU723184B2 (pt)
BG (1) BG63663B1 (pt)
BR (1) BR9711381A (pt)
CA (1) CA2265047A1 (pt)
CZ (1) CZ295058B6 (pt)
DE (1) DE69709127T2 (pt)
EE (1) EE9900082A (pt)
ES (1) ES2173476T3 (pt)
GB (1) GB9618056D0 (pt)
HK (1) HK1020722A1 (pt)
HU (1) HU229253B1 (pt)
IL (1) IL128715A (pt)
IN (1) IN186429B (pt)
NO (1) NO322795B1 (pt)
NZ (1) NZ334817A (pt)
PL (1) PL190151B1 (pt)
PT (1) PT925275E (pt)
SK (1) SK26499A3 (pt)
TR (1) TR199900405T2 (pt)
WO (1) WO1998008804A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618056D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
US6262303B1 (en) * 1998-05-08 2001-07-17 Dibra S.P.A. Process for the preparation of S-N,N′-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)-amino]-2,4,6-triiodo-1,3-benzenedicarboxamide
ITMI20010773A1 (it) 2001-04-11 2002-10-11 Chemi Spa Processo per la produzione di ioexolo ad elevata purezza
TWI288654B (en) * 2001-05-17 2007-10-21 Ind Tech Res Inst Process for the purification of water-soluble non-ionic contrast agents
NO20033058D0 (no) * 2003-07-03 2003-07-03 Amersham Health As Prosess
NO20053687D0 (no) * 2005-07-29 2005-07-29 Amersham Health As Crystallisation Process.
NO20053676D0 (no) 2005-07-29 2005-07-29 Amersham Health As Crystallisation Process
PT103391B (pt) * 2005-11-24 2008-10-30 Hovione Farmaciencia S A Processo para fabrico de lohexol
WO2009091758A1 (en) * 2008-01-14 2009-07-23 Mallinckrodt Inc. Process for the preparation of iosimenol
WO2015133651A1 (en) * 2014-03-04 2015-09-11 Otsuka Pharmaceutical Co., Ltd. Iohexol powder and method of using the same
CN110054569B (zh) * 2019-05-17 2022-05-17 浙江海洲制药有限公司 一种制备碘海醇的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1548594A (en) * 1922-05-27 1925-08-04 Helios Machine Company Motion-converting mechanism
CH608189A5 (pt) * 1974-12-13 1978-12-29 Savac Ag
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
IT1207226B (it) * 1979-08-09 1989-05-17 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
DK162045C (da) * 1982-10-01 1992-02-10 Nyegaard & Co As Trijodbenzenderivater, fremgangsmaade til fremstilling deraf og radiologiske praeparater indeholdende saadanne forbindelser
NO161368C (no) * 1982-11-08 1989-08-09 Nyegaard & Co As Roentgenkontrastmidler samt radiologiske preparater derav.
IL94718A (en) * 1989-07-05 1994-10-21 Schering Ag Non-ionic carboxamide contrast agent and method of preparation
US5527926A (en) * 1990-11-26 1996-06-18 Bracco International B.V. Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures
US5371278A (en) * 1994-03-25 1994-12-06 Mallinckrodt Medical Pmc Synthesis of ioversol using a minimal excess of acetoxyacetylchloride
US5624957A (en) * 1995-06-06 1997-04-29 Bristol-Myers Squibb Company Rary-specific retinobenzoic acid derivatives
GB9618056D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
GB9618055D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process

Also Published As

Publication number Publication date
TR199900405T2 (xx) 1999-06-21
JP2000517312A (ja) 2000-12-26
HK1020722A1 (en) 2000-05-19
HUP9904325A3 (en) 2000-06-28
US5948940A (en) 1999-09-07
GB9618056D0 (en) 1996-10-09
KR100517588B1 (ko) 2005-09-29
CN1120148C (zh) 2003-09-03
US6153796A (en) 2000-11-28
ATE210631T1 (de) 2001-12-15
CZ295058B6 (cs) 2005-05-18
CN1228763A (zh) 1999-09-15
DE69709127T2 (de) 2002-08-14
IL128715A (en) 2002-08-14
HU229253B1 (en) 2013-10-28
AU4123697A (en) 1998-03-19
ES2173476T3 (es) 2002-10-16
NO322795B1 (no) 2006-12-11
NZ334817A (en) 2000-09-29
EP0925275A1 (en) 1999-06-30
CA2265047A1 (en) 1998-03-05
IN186429B (pt) 2001-09-01
KR20000035945A (ko) 2000-06-26
HUP9904325A2 (hu) 2000-04-28
PL190151B1 (pl) 2005-11-30
AU723184B2 (en) 2000-08-17
IL128715A0 (en) 2000-01-31
JP3780002B2 (ja) 2006-05-31
SK26499A3 (en) 1999-08-06
NO990889D0 (no) 1999-02-25
PL331706A1 (en) 1999-08-02
EE9900082A (et) 1999-10-15
BG63663B1 (bg) 2002-08-30
BR9711381A (pt) 1999-08-17
EP0925275B1 (en) 2001-12-12
BG103289A (en) 2000-01-31
DE69709127D1 (de) 2002-01-24
CZ66999A3 (cs) 1999-08-11
WO1998008804A1 (en) 1998-03-05
NO990889L (no) 1999-02-25

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