EE9900082A - Protsess ioheksoolide tootmiseks - Google Patents

Protsess ioheksoolide tootmiseks

Info

Publication number
EE9900082A
EE9900082A EEP199900082A EE9900082A EE9900082A EE 9900082 A EE9900082 A EE 9900082A EE P199900082 A EEP199900082 A EE P199900082A EE 9900082 A EE9900082 A EE 9900082A EE 9900082 A EE9900082 A EE 9900082A
Authority
EE
Estonia
Prior art keywords
production
iohexols
triiodophthalamide
iohexol
dihydroxypropyl
Prior art date
Application number
EEP199900082A
Other languages
English (en)
Inventor
Einar Ingvoldstad Odd
Malthe-S�renssen Dick
Myrbr�ten Espen
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of EE9900082A publication Critical patent/EE9900082A/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/08Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
EEP199900082A 1996-08-29 1997-08-29 Protsess ioheksoolide tootmiseks EE9900082A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9618056.7A GB9618056D0 (en) 1996-08-29 1996-08-29 Process
PCT/GB1997/002332 WO1998008804A1 (en) 1996-08-29 1997-08-29 Process for iohexol manufacture

Publications (1)

Publication Number Publication Date
EE9900082A true EE9900082A (et) 1999-10-15

Family

ID=10799120

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900082A EE9900082A (et) 1996-08-29 1997-08-29 Protsess ioheksoolide tootmiseks

Country Status (26)

Country Link
US (2) US5948940A (et)
EP (1) EP0925275B1 (et)
JP (1) JP3780002B2 (et)
KR (1) KR100517588B1 (et)
CN (1) CN1120148C (et)
AT (1) ATE210631T1 (et)
AU (1) AU723184B2 (et)
BG (1) BG63663B1 (et)
BR (1) BR9711381A (et)
CA (1) CA2265047A1 (et)
CZ (1) CZ295058B6 (et)
DE (1) DE69709127T2 (et)
EE (1) EE9900082A (et)
ES (1) ES2173476T3 (et)
GB (1) GB9618056D0 (et)
HK (1) HK1020722A1 (et)
HU (1) HU229253B1 (et)
IL (1) IL128715A (et)
IN (1) IN186429B (et)
NO (1) NO322795B1 (et)
NZ (1) NZ334817A (et)
PL (1) PL190151B1 (et)
PT (1) PT925275E (et)
SK (1) SK26499A3 (et)
TR (1) TR199900405T2 (et)
WO (1) WO1998008804A1 (et)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618056D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
US6262303B1 (en) * 1998-05-08 2001-07-17 Dibra S.P.A. Process for the preparation of S-N,N′-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)-amino]-2,4,6-triiodo-1,3-benzenedicarboxamide
ITMI20010773A1 (it) * 2001-04-11 2002-10-11 Chemi Spa Processo per la produzione di ioexolo ad elevata purezza
TWI288654B (en) * 2001-05-17 2007-10-21 Ind Tech Res Inst Process for the purification of water-soluble non-ionic contrast agents
NO20033058D0 (no) * 2003-07-03 2003-07-03 Amersham Health As Prosess
NO20053676D0 (no) 2005-07-29 2005-07-29 Amersham Health As Crystallisation Process
NO20053687D0 (no) * 2005-07-29 2005-07-29 Amersham Health As Crystallisation Process.
PT103391B (pt) 2005-11-24 2008-10-30 Hovione Farmaciencia S A Processo para fabrico de lohexol
US8445725B2 (en) * 2008-01-14 2013-05-21 Mallinckrodt Llc Process for the preparation of iosimenol
RU2711501C2 (ru) * 2014-03-04 2020-01-17 Оцука Фармасьютикал Ко., Лтд. Порошок йогексола и способ его применения
CN110054569B (zh) * 2019-05-17 2022-05-17 浙江海洲制药有限公司 一种制备碘海醇的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1548594A (en) * 1922-05-27 1925-08-04 Helios Machine Company Motion-converting mechanism
CH608189A5 (et) * 1974-12-13 1978-12-29 Savac Ag
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
IT1207226B (it) * 1979-08-09 1989-05-17 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
DK162045C (da) * 1982-10-01 1992-02-10 Nyegaard & Co As Trijodbenzenderivater, fremgangsmaade til fremstilling deraf og radiologiske praeparater indeholdende saadanne forbindelser
EP0108638B1 (en) * 1982-11-08 1986-07-16 NYEGAARD & CO. A/S X-ray contrast agents
IL94718A (en) * 1989-07-05 1994-10-21 Schering Ag Non-ionic carboxamide contrast agent and method of preparation
US5527926A (en) * 1990-11-26 1996-06-18 Bracco International B.V. Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures
US5371278A (en) * 1994-03-25 1994-12-06 Mallinckrodt Medical Pmc Synthesis of ioversol using a minimal excess of acetoxyacetylchloride
US5624957A (en) * 1995-06-06 1997-04-29 Bristol-Myers Squibb Company Rary-specific retinobenzoic acid derivatives
GB9618055D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
GB9618056D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process

Also Published As

Publication number Publication date
GB9618056D0 (en) 1996-10-09
AU723184B2 (en) 2000-08-17
ES2173476T3 (es) 2002-10-16
PL331706A1 (en) 1999-08-02
US6153796A (en) 2000-11-28
WO1998008804A1 (en) 1998-03-05
CN1120148C (zh) 2003-09-03
TR199900405T2 (xx) 1999-06-21
NO990889L (no) 1999-02-25
EP0925275A1 (en) 1999-06-30
KR20000035945A (ko) 2000-06-26
CZ295058B6 (cs) 2005-05-18
BG103289A (en) 2000-01-31
CA2265047A1 (en) 1998-03-05
NO990889D0 (no) 1999-02-25
EP0925275B1 (en) 2001-12-12
NO322795B1 (no) 2006-12-11
HUP9904325A3 (en) 2000-06-28
IL128715A0 (en) 2000-01-31
JP3780002B2 (ja) 2006-05-31
IL128715A (en) 2002-08-14
KR100517588B1 (ko) 2005-09-29
BG63663B1 (bg) 2002-08-30
US5948940A (en) 1999-09-07
HU229253B1 (en) 2013-10-28
IN186429B (et) 2001-09-01
JP2000517312A (ja) 2000-12-26
NZ334817A (en) 2000-09-29
HUP9904325A2 (hu) 2000-04-28
ATE210631T1 (de) 2001-12-15
CN1228763A (zh) 1999-09-15
CZ66999A3 (cs) 1999-08-11
PL190151B1 (pl) 2005-11-30
HK1020722A1 (en) 2000-05-19
PT925275E (pt) 2002-05-31
BR9711381A (pt) 1999-08-17
AU4123697A (en) 1998-03-19
DE69709127D1 (de) 2002-01-24
SK26499A3 (en) 1999-08-06
DE69709127T2 (de) 2002-08-14

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