HUP9900799A2 - Eljárás lantán-karbonát-hidrátok előállítására és az azokat tartalmazó gyógyászati készítmények - Google Patents

Eljárás lantán-karbonát-hidrátok előállítására és az azokat tartalmazó gyógyászati készítmények

Info

Publication number
HUP9900799A2
HUP9900799A2 HU9900799A HUP9900799A HUP9900799A2 HU P9900799 A2 HUP9900799 A2 HU P9900799A2 HU 9900799 A HU9900799 A HU 9900799A HU P9900799 A HUP9900799 A HU P9900799A HU P9900799 A2 HUP9900799 A2 HU P9900799A2
Authority
HU
Hungary
Prior art keywords
lanthanum
lanthanum carbonate
carbonate
hydrated
pharmaceutical composition
Prior art date
Application number
HU9900799A
Other languages
English (en)
Inventor
Barry Anthony Murrer
Nigel Anthony Powell
Original Assignee
Johnson Matthey Public Limited Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10771896&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP9900799(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Johnson Matthey Public Limited Company filed Critical Johnson Matthey Public Limited Company
Publication of HUP9900799A2 publication Critical patent/HUP9900799A2/hu
Publication of HUP9900799A3 publication Critical patent/HUP9900799A3/hu
Publication of HU224198B1 publication Critical patent/HU224198B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/244—Lanthanides; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
    • C01F17/00—Compounds of rare earth metals
    • C01F17/20—Compounds containing only rare earth metals as the metal element
    • C01F17/247—Carbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/70—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data
    • C01P2002/72—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data by d-values or two theta-values, e.g. as X-ray diagram

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Geology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Meghatárőzőtt mennyiségű kristályvizet tartalmazó, La2(CO3)3.xH2Oáltalánős képletű, hidratált lantán-karbőnát, ahől a fenti általánősképletben x értéke 3 és 6 között, és előnyösen 3,8 és 4,5 között van. Atalálmány tárgyát képezik tővábbá az említett, hidratált lantán-karbőnátőt tartalmazó gyógyászati készítmények, tővábbá eljárás azemlített, hidratált lantán-karbőnát előállítására. Az említett,hidratált lantán-karbőnátőt a találmány értelmében úgy állítják elő,hőgy a) lantán-őxidőt egy őlyan savval reagáltatnak, amely a lantán őldhatósóját szőlgáltatja; b) az így kapőtt lantán-só őldatát egy alkálifém-karbőnáttalreagáltatják, és így nedves, kiszűrt főrmában lantán-karbőnát-őktahidrátőt állítanak elő; és c) a nedves, kiszűrt lantán-karbőnát-őktahidrátőt szabályőzőtt módőnszárítva 3-6 mől kristályvizet tartalmazó lantán-karbőnátőt állítanakelő. ŕ
HU9900799A 1995-03-25 1996-03-19 Lantán-karbonát-hidrátokat tartalmazó gyógyászati készítmények hiperfoszfatémia kezelésére és eljárás előállításukra HU224198B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9506126.3A GB9506126D0 (en) 1995-03-25 1995-03-25 Pharmaceutical composition and method
PCT/GB1996/000575 WO1996030029A1 (en) 1995-03-25 1996-03-19 Pharmaceutical composition containing selected lanthanum carbonate hydrates

Publications (3)

Publication Number Publication Date
HUP9900799A2 true HUP9900799A2 (hu) 1999-09-28
HUP9900799A3 HUP9900799A3 (en) 2000-10-30
HU224198B1 HU224198B1 (hu) 2005-06-28

Family

ID=10771896

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9900799A HU224198B1 (hu) 1995-03-25 1996-03-19 Lantán-karbonát-hidrátokat tartalmazó gyógyászati készítmények hiperfoszfatémia kezelésére és eljárás előállításukra

Country Status (28)

Country Link
US (1) US5968976A (hu)
EP (1) EP0817639B1 (hu)
JP (1) JP3224544B2 (hu)
KR (1) KR100329340B1 (hu)
CN (1) CN1102393C (hu)
AT (1) ATE209923T1 (hu)
AU (1) AU702073B2 (hu)
BR (1) BR9607926A (hu)
CA (1) CA2216437C (hu)
CZ (1) CZ293494B6 (hu)
DE (4) DE69617659D1 (hu)
DK (1) DK0817639T3 (hu)
EA (1) EA000270B1 (hu)
EE (1) EE04096B1 (hu)
ES (1) ES2170223T3 (hu)
GB (1) GB9506126D0 (hu)
HK (1) HK1008182A1 (hu)
HU (1) HU224198B1 (hu)
MX (1) MX9707334A (hu)
NO (1) NO313488B1 (hu)
NZ (1) NZ303260A (hu)
PL (1) PL184315B1 (hu)
PT (1) PT817639E (hu)
SK (1) SK282607B6 (hu)
TR (1) TR199701030T1 (hu)
TW (1) TW436288B (hu)
WO (1) WO1996030029A1 (hu)
ZA (1) ZA962369B (hu)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9720061D0 (en) * 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
GB0015745D0 (en) * 2000-06-27 2000-08-16 Shire Holdings Ag Treatment of bone diseases
DE60239329D1 (de) 2001-04-23 2011-04-14 Shire Int Licensing Bv Verwendung von lanthankarbonat zur prävention von nierensteinleiden
AU2003229437A1 (en) * 2002-05-08 2003-11-11 Shire Holding Ag Use of lanthanum for the treatment of hypercalcemia and bone metastasis
US20040161474A1 (en) * 2002-05-24 2004-08-19 Moerck Rudi E. Rare earth metal compounds methods of making, and methods of using the same
US20060083791A1 (en) 2002-05-24 2006-04-20 Moerck Rudi E Rare earth metal compounds methods of making, and methods of using the same
CN100526219C (zh) * 2002-08-14 2009-08-12 爱尔达纳米公司 稀土金属化合物、其制造方法及其使用方法
EP1647524A3 (en) * 2002-08-14 2006-09-13 Altair Nanomaterials Inc. Rare earth metal compounds, methods of making, and methods of using the same
US7381428B2 (en) * 2003-08-26 2008-06-03 Shire International Licensing B.V. Stabilized lanthanum carbonate compositions
CA2536959C (en) * 2003-08-26 2011-08-02 Shire Holdings Ag Pharmaceutical formulation comprising lanthanum compounds
EP1708723A4 (en) * 2004-07-27 2006-12-20 Shire Pharmaceuticals Inc METHOD FOR TREATING HYPERPHOSPHATEMIA USING LANTHAN HYDROXYCARBONATE
US7700608B2 (en) * 2004-08-04 2010-04-20 Shire Holdings Ag Quinazoline derivatives and their use in the treatment of thrombocythemia
JP2008516971A (ja) * 2004-10-15 2008-05-22 アルテアーナノ，インコーポレーテッド 錠剤による負荷が軽減されるリン酸塩結合剤
ITME20040015A1 (it) * 2004-12-07 2005-03-07 Vincenzo Savica Chewing gum, caramelle gommose, pastiglie, compresse a lento rilascio di chelanti fosfato e/o fosforo salivare e capsule a lento rilascio di chelanti fosfato e/o fosforo a livello gastroenterico.
GB0502787D0 (en) * 2005-02-10 2005-03-16 Ineos Silicas Ltd Pharmaceuticlly active compounds, their manufacture, compositions containing them and their use
EP1698233A1 (en) * 2005-03-01 2006-09-06 Bayer HealthCare AG Reduction of digestibility of phosphorus in animal nutrition
JP2009504781A (ja) * 2005-08-17 2009-02-05 アルテアナノ インコーポレイテッド 家畜における高リン血症：治療のための組成物、及び治療方法
CA2619643A1 (en) * 2005-08-17 2007-02-22 Altairnano, Inc. Treatment of chronic renal failure and other conditions in domestic animals: compositions and methods
US20070104799A1 (en) * 2005-11-09 2007-05-10 Shire International Licensing B.V. Treatment of chronic kidney disease (CKD) subjects using lanthanum compounds
MY157620A (en) 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
CN100398112C (zh) * 2006-03-24 2008-07-02 辽宁诺康生物制药有限责任公司 一种治疗血磷酸盐过多症的药物及其制备方法
US20070259052A1 (en) * 2006-05-05 2007-11-08 Shire International Licensing B.V. Assay for lanthanum hydroxycarbonate
ATE530896T1 (de) * 2006-05-05 2011-11-15 Shire Int Licensing Bv Assay für lanthan-hydroxycarbonat
CN101077338B (zh) * 2006-05-24 2012-06-20 天津大学 纳米碳酸镧口腔崩解片及制备方法
GB0714670D0 (en) 2007-07-27 2007-09-05 Ineos Healthcare Ltd Use
GB0720220D0 (en) * 2007-10-16 2007-11-28 Ineos Healthcare Ltd Compound
US8974824B2 (en) * 2008-03-26 2015-03-10 Mylan Laboratories Ltd. Lanthanum composition
WO2010085520A1 (en) * 2009-01-21 2010-07-29 Mylan Inc. Disintegrable formulations of lanthanum carbonate
WO2010106557A2 (en) * 2009-03-20 2010-09-23 Panacea Biotec Limited Stable pharmaceutical formulations comprising anhydrous lanthanum carbonate and process for preparation thereof
US20120058200A1 (en) * 2009-05-15 2012-03-08 Natco Pharma Limited Process for the preparation of lanthanum carbonate dihydrate
GB0913525D0 (en) 2009-08-03 2009-09-16 Ineos Healthcare Ltd Method
GB201001779D0 (en) 2010-02-04 2010-03-24 Ineos Healthcare Ltd Composition
CN103037870B (zh) * 2010-05-12 2016-05-25 斯派克托姆制药公司 碱式碳酸镧、碳酸氧镧及其制造方法和用途
EP2441436A1 (de) * 2010-10-13 2012-04-18 Fresenius Medical Care Deutschland GmbH Phosphatbinderformulierung zur einfachen Einnahme
US8263119B2 (en) 2010-12-01 2012-09-11 Shire Llc Capsule formulations containing lanthanum compounds
US8697132B2 (en) 2010-12-01 2014-04-15 Shire Llc Capsule and powder formulations containing lanthanum compounds
WO2012098562A2 (en) 2011-01-19 2012-07-26 Panacea Biotec Limited Liquid oral compositions of lanthanum salts
CN102432055B (zh) * 2011-09-23 2013-10-16 北京大学 用于治疗高磷血症的碳酸镧纳米颗粒、其制备方法及用途
CN102442692B (zh) * 2011-09-23 2014-08-27 北京大学 碳酸镧水合物的制备方法
EA021712B1 (ru) * 2012-06-12 2015-08-31 Общество С Ограниченной Ответственностью "Рубикон" Противовоспалительное средство для лечения контактного дерматита
CN103251648B (zh) 2013-05-15 2015-08-05 乔敏 治疗血磷酸盐过多症及缺铁性贫血症的铁基蒙脱石药物及其制备方法
JP6225270B2 (ja) * 2014-10-02 2017-11-01 東和薬品株式会社 粒度調整された炭酸ランタン水和物からなる医薬
CN104473963B (zh) * 2014-12-24 2017-10-10 厦门科明达科技有限公司 稀土化学药碳酸镧咀嚼片的制备方法
US10058569B2 (en) * 2015-06-24 2018-08-28 Lupin Limited Lanthanum carbonate compositions
CN105125575B (zh) * 2015-08-07 2018-06-08 康臣药业(内蒙古)有限责任公司 一种治疗高磷酸盐血症药物的制备方法
ES2848476T3 (es) 2015-11-30 2021-08-09 Toray Industries Columna de adsorción de fibra porosa y fósforo
CN107876000A (zh) * 2017-10-30 2018-04-06 浙江大学 一种纳米除磷剂、制备方法及应用
CN110579499A (zh) * 2018-06-08 2019-12-17 北京华睿鼎信科技有限公司 一种碳酸镧或其制剂中碱式碳酸镧杂质的检定方法
MX2021004516A (es) * 2018-10-26 2021-06-15 Sumitomo Chemical Co Metodo para produccion de hidrato de carbonato de lantano.
CN111620363A (zh) * 2020-06-13 2020-09-04 南京卡文迪许生物工程技术有限公司 一种四水合碳酸镧的制备方法及其产品
WO2022014122A1 (ja) 2020-07-13 2022-01-20 恒隆 川口 セリウム化合物を有効成分として含む、医薬組成物
CN114477265B (zh) * 2020-11-13 2023-11-03 南京正济医药研究有限公司 一种四水碳酸镧的制备方法
CN115849429B (zh) * 2023-01-06 2024-01-23 湖南明瑞制药股份有限公司 一种小粒径四水碳酸镧的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06705B2 (ja) * 1985-12-19 1994-01-05 旭化成工業株式会社 リン酸イオンの固定化剤

Also Published As

Publication number Publication date
DE122007000022I2 (de) 2009-09-17
CZ301797A3 (cs) 1998-07-15
EP0817639A1 (en) 1998-01-14
DE69617659T2 (de) 2002-10-02
HU224198B1 (hu) 2005-06-28
EA199700266A1 (ru) 1998-02-26
CZ293494B6 (cs) 2004-05-12
CN1184428A (zh) 1998-06-10
NO313488B1 (no) 2002-10-14
NO974425L (no) 1997-11-24
CA2216437A1 (en) 1996-10-03
GB9506126D0 (en) 1995-05-10
TW436288B (en) 2001-05-28
DE122007000022I1 (de) 2007-07-12
SK128897A3 (en) 1998-10-07
JP3224544B2 (ja) 2001-10-29
TR199701030T1 (xx) 1998-06-22
NO974425D0 (no) 1997-09-24
PL322450A1 (en) 1998-02-02
SK282607B6 (sk) 2002-10-08
CA2216437C (en) 2002-10-22
US5968976A (en) 1999-10-19
EP0817639B1 (en) 2001-12-05
BR9607926A (pt) 1998-06-09
DE69617659D1 (de) 2002-01-17
DE69617659T4 (de) 2007-09-27
EE9700325A (et) 1998-06-15
NZ303260A (en) 2000-01-28
ZA962369B (en) 1996-11-18
DK0817639T3 (da) 2002-04-02
AU4951496A (en) 1996-10-16
HK1008182A1 (en) 1999-05-07
JPH11503119A (ja) 1999-03-23
KR100329340B1 (ko) 2002-06-20
ES2170223T3 (es) 2002-08-01
HUP9900799A3 (en) 2000-10-30
MX9707334A (es) 1998-07-31
EE04096B1 (et) 2003-08-15
CN1102393C (zh) 2003-03-05
ATE209923T1 (de) 2001-12-15
EA000270B1 (ru) 1999-02-25
PL184315B1 (pl) 2002-10-31
AU702073B2 (en) 1999-02-11
KR19980703280A (ko) 1998-10-15
WO1996030029A1 (en) 1996-10-03
PT817639E (pt) 2002-05-31

Similar Documents

Publication Publication Date Title
HUP9900799A2 (hu) Eljárás lantán-karbonát-hidrátok előállítására és az azokat tartalmazó gyógyászati készítmények
HUP9701416A2 (hu) Fenilszubsztituált alkenilkarbonsav-guanididek, eljárás azok előállítására, alkalmazásuk és az azokat tartalmazó gyógyszerkészítmények
GB1465442A (en) Method of manufacturing carboxymethyl cellulose
TR199802039T2 (xx) Yeni alfa-hidroksilik asit t�revleri, �retimleri ve kullan�mlar�.
ES476919A1 (es) Procedimiento para la preparacion de nuevos compuestos de 2-pirrolidona.
GB1436487A (en) Compositions for oral hygiene
ES460664A1 (es) Un metodo de preparar una sal de cerio de sulfadiazina.
GB1489400A (en) Aluminium hydroxycarbonate hydrate
GB1488444A (en) Process for producing aluminium chloro-hydroxides
ES412423A1 (es) Procedimiento para la produccion de clerohidroxides de alu-minio.
JPS5780340A (en) Preparation of basic aluminum lactate
GB2006201A (en) Production of nitroguanidine from guanidine nitrate and nitric acid
GB1439907A (en) Process for the purification of lithium hexafluoroarsenate
IE40245B1 (en) Aluminium hydroxychlorides
ES2072191A1 (es) Prodecimiento de obtencion de hidroxicloruro de zinc,zn5 (oh)8 cl2.h20y su uso como corrector de zinc.
JPS554349A (en) Preparation of creatine
WO1989009766A3 (en) Process for the preparation of 2,4,6-triiodo-5-amino-n-alkylisophthalamic acid
IE45984L (en) Manufacture of aluminium ethylphosphite
GB1462728A (en) Process for producing hydroxy-aluminum nitrate polymer
SU502862A1 (ru) Способ получени пропиленхлоргидрина
HUP0000199A2 (hu) Eljárás nagytisztaságú kaptopril előállítására
SU643504A2 (ru) Способ получени координационных соединений силиконатов щелочных металлов
JPS55125164A (en) Coating pigment and production thereof
ES436472A2 (es) Procedimiento para la produccion de clorohidroxidos de alu- minio.
GR81060B (en) Lorazepam-containing sleeping pill

Legal Events

Date Code Title Description
HFG4 Patent granted, date of granting

Effective date: 20050420

GB9A Succession in title

Owner name: SHIRE INTERNATIONAL LICENSING B.V., NL

Free format text: FORMER OWNER(S): ANORMED CORPORATION, CA; ANORMED INC., CA; JOHNSON MATTHEY PUBLIC LIMITED COMPANY, GB