EA199700266A1 - Фармацевтическая композиция, содержащая выбранные гидраты карбоната лантана - Google Patents
Фармацевтическая композиция, содержащая выбранные гидраты карбоната лантанаInfo
- Publication number
- EA199700266A1 EA199700266A1 EA199700266A EA199700266A EA199700266A1 EA 199700266 A1 EA199700266 A1 EA 199700266A1 EA 199700266 A EA199700266 A EA 199700266A EA 199700266 A EA199700266 A EA 199700266A EA 199700266 A1 EA199700266 A1 EA 199700266A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- hydrates
- lanthane
- carbonate
- pharmaceutical composition
- composition containing
- Prior art date
Links
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 title 1
- 150000004677 hydrates Chemical class 0.000 title 1
- FZLIPJUXYLNCLC-UHFFFAOYSA-N lanthanum atom Chemical compound [La] FZLIPJUXYLNCLC-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 208000001647 Renal Insufficiency Diseases 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 201000005991 hyperphosphatemia Diseases 0.000 abstract 1
- 201000006370 kidney failure Diseases 0.000 abstract 1
- AFCUGQOTNCVYSW-UHFFFAOYSA-H lanthanum(3+);tricarbonate;hydrate Chemical class O.[La+3].[La+3].[O-]C([O-])=O.[O-]C([O-])=O.[O-]C([O-])=O AFCUGQOTNCVYSW-UHFFFAOYSA-H 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/244—Lanthanides; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
- C01F17/00—Compounds of rare earth metals
- C01F17/20—Compounds containing only rare earth metals as the metal element
- C01F17/247—Carbonates
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C01P2002/00—Crystal-structural characteristics
- C01P2002/70—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data
- C01P2002/72—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data by d-values or two theta-values, e.g. as X-ray diagram
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Geology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Выбранные гидраты карбоната лантана могут вводиться в желудочно-кишечный тракт для лечения гиперфосфатемии у пациентов с почечной недостаточностью.Международная заявка была опубликована вместе с отчетом о международном поиске.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9506126.3A GB9506126D0 (en) | 1995-03-25 | 1995-03-25 | Pharmaceutical composition and method |
PCT/GB1996/000575 WO1996030029A1 (en) | 1995-03-25 | 1996-03-19 | Pharmaceutical composition containing selected lanthanum carbonate hydrates |
Publications (2)
Publication Number | Publication Date |
---|---|
EA199700266A1 true EA199700266A1 (ru) | 1998-02-26 |
EA000270B1 EA000270B1 (ru) | 1999-02-25 |
Family
ID=10771896
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA199700266A EA000270B1 (ru) | 1995-03-25 | 1996-03-19 | Фармацевтическая композиция, содержащая выбранные гидраты карбоната лантана |
Country Status (28)
Country | Link |
---|---|
US (1) | US5968976A (ru) |
EP (1) | EP0817639B1 (ru) |
JP (1) | JP3224544B2 (ru) |
KR (1) | KR100329340B1 (ru) |
CN (1) | CN1102393C (ru) |
AT (1) | ATE209923T1 (ru) |
AU (1) | AU702073B2 (ru) |
BR (1) | BR9607926A (ru) |
CA (1) | CA2216437C (ru) |
CZ (1) | CZ293494B6 (ru) |
DE (4) | DE122007000022I2 (ru) |
DK (1) | DK0817639T3 (ru) |
EA (1) | EA000270B1 (ru) |
EE (1) | EE04096B1 (ru) |
ES (1) | ES2170223T3 (ru) |
GB (1) | GB9506126D0 (ru) |
HK (1) | HK1008182A1 (ru) |
HU (1) | HU224198B1 (ru) |
MX (1) | MX9707334A (ru) |
NO (1) | NO313488B1 (ru) |
NZ (1) | NZ303260A (ru) |
PL (1) | PL184315B1 (ru) |
PT (1) | PT817639E (ru) |
SK (1) | SK282607B6 (ru) |
TR (1) | TR199701030T1 (ru) |
TW (1) | TW436288B (ru) |
WO (1) | WO1996030029A1 (ru) |
ZA (1) | ZA962369B (ru) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9720061D0 (en) | 1997-09-19 | 1997-11-19 | Crosfield Joseph & Sons | Metal compounds as phosphate binders |
GB0015745D0 (en) * | 2000-06-27 | 2000-08-16 | Shire Holdings Ag | Treatment of bone diseases |
CA2442414C (en) * | 2001-04-23 | 2011-02-01 | Anormed, Inc. | Use of rare earth compounds for the prevention of kidney stone disease |
WO2003094933A2 (en) * | 2002-05-08 | 2003-11-20 | Shire Holding Ag | Use of lanthanum for the treatment of hypercalcemia and bone metastasis |
US20040161474A1 (en) * | 2002-05-24 | 2004-08-19 | Moerck Rudi E. | Rare earth metal compounds methods of making, and methods of using the same |
US20060083791A1 (en) | 2002-05-24 | 2006-04-20 | Moerck Rudi E | Rare earth metal compounds methods of making, and methods of using the same |
EP2194028B1 (en) * | 2002-08-14 | 2022-01-26 | Unicycive Therapeutics, Inc. | Rare earth metal compounds, methods of making, and methods of using the same |
CN100526219C (zh) * | 2002-08-14 | 2009-08-12 | 爱尔达纳米公司 | 稀土金属化合物、其制造方法及其使用方法 |
US7381428B2 (en) * | 2003-08-26 | 2008-06-03 | Shire International Licensing B.V. | Stabilized lanthanum carbonate compositions |
PT2792363T (pt) * | 2003-08-26 | 2016-09-26 | Shire Biopharmaceuticals Holdings Ireland Ltd | Formulação farmacêutica compreendendo compostos de lantânio |
US20060153932A1 (en) * | 2004-07-27 | 2006-07-13 | Shire Pharmaceuticals, Inc. | Method of treating hyperphosphataemia using lanthanum hydroxycarbonate |
US7700608B2 (en) * | 2004-08-04 | 2010-04-20 | Shire Holdings Ag | Quinazoline derivatives and their use in the treatment of thrombocythemia |
CA2583548A1 (en) * | 2004-10-15 | 2006-04-27 | Altairnano, Inc. | Phosphate binder with reduced pill burden |
ITME20040015A1 (it) * | 2004-12-07 | 2005-03-07 | Vincenzo Savica | Chewing gum, caramelle gommose, pastiglie, compresse a lento rilascio di chelanti fosfato e/o fosforo salivare e capsule a lento rilascio di chelanti fosfato e/o fosforo a livello gastroenterico. |
GB0502787D0 (en) * | 2005-02-10 | 2005-03-16 | Ineos Silicas Ltd | Pharmaceuticlly active compounds, their manufacture, compositions containing them and their use |
EP1698233A1 (en) * | 2005-03-01 | 2006-09-06 | Bayer HealthCare AG | Reduction of digestibility of phosphorus in animal nutrition |
EP1928349A4 (en) * | 2005-08-17 | 2008-10-01 | Altairnano Inc | COMPOSITIONS AND METHODS FOR TREATING CHRONIC RENAL FAILURE AND OTHER CONDITIONS IN DOMESTIC ANIMALS |
ES2311443T1 (es) * | 2005-08-17 | 2009-02-16 | Altairnano, Inc | Hiperfosfatemia en animales domesticos: composiciones y procedimientos de tratamiento. |
US20070104799A1 (en) * | 2005-11-09 | 2007-05-10 | Shire International Licensing B.V. | Treatment of chronic kidney disease (CKD) subjects using lanthanum compounds |
MY157620A (en) | 2006-01-31 | 2016-06-30 | Cytochroma Dev Inc | A granular material of a solid water-soluble mixed metal compound capable of binding phosphate |
CN100398112C (zh) * | 2006-03-24 | 2008-07-02 | 辽宁诺康生物制药有限责任公司 | 一种治疗血磷酸盐过多症的药物及其制备方法 |
US20070259052A1 (en) | 2006-05-05 | 2007-11-08 | Shire International Licensing B.V. | Assay for lanthanum hydroxycarbonate |
ATE530896T1 (de) * | 2006-05-05 | 2011-11-15 | Shire Int Licensing Bv | Assay für lanthan-hydroxycarbonat |
CN101077338B (zh) * | 2006-05-24 | 2012-06-20 | 天津大学 | 纳米碳酸镧口腔崩解片及制备方法 |
GB0714670D0 (en) | 2007-07-27 | 2007-09-05 | Ineos Healthcare Ltd | Use |
GB0720220D0 (en) * | 2007-10-16 | 2007-11-28 | Ineos Healthcare Ltd | Compound |
US8974824B2 (en) * | 2008-03-26 | 2015-03-10 | Mylan Laboratories Ltd. | Lanthanum composition |
SI2389070T1 (sl) * | 2009-01-21 | 2013-11-29 | Mylan Inc. | Razkrojne formulacije lantanovega karbonata |
WO2010106557A2 (en) * | 2009-03-20 | 2010-09-23 | Panacea Biotec Limited | Stable pharmaceutical formulations comprising anhydrous lanthanum carbonate and process for preparation thereof |
WO2010131255A1 (en) * | 2009-05-15 | 2010-11-18 | Natco Pharma Limited | Process for the preparation of lanthanum carbonate dihydrate |
GB0913525D0 (en) | 2009-08-03 | 2009-09-16 | Ineos Healthcare Ltd | Method |
GB201001779D0 (en) | 2010-02-04 | 2010-03-24 | Ineos Healthcare Ltd | Composition |
CN103037870B (zh) | 2010-05-12 | 2016-05-25 | 斯派克托姆制药公司 | 碱式碳酸镧、碳酸氧镧及其制造方法和用途 |
EP2441436A1 (de) * | 2010-10-13 | 2012-04-18 | Fresenius Medical Care Deutschland GmbH | Phosphatbinderformulierung zur einfachen Einnahme |
US8697132B2 (en) | 2010-12-01 | 2014-04-15 | Shire Llc | Capsule and powder formulations containing lanthanum compounds |
US8263119B2 (en) | 2010-12-01 | 2012-09-11 | Shire Llc | Capsule formulations containing lanthanum compounds |
US9402808B2 (en) | 2011-01-19 | 2016-08-02 | Panacea Biotec Limited | Liquid oral composition of lanthanum salts |
CN102442692B (zh) * | 2011-09-23 | 2014-08-27 | 北京大学 | 碳酸镧水合物的制备方法 |
CN102432055B (zh) * | 2011-09-23 | 2013-10-16 | 北京大学 | 用于治疗高磷血症的碳酸镧纳米颗粒、其制备方法及用途 |
EA021712B1 (ru) * | 2012-06-12 | 2015-08-31 | Общество С Ограниченной Ответственностью "Рубикон" | Противовоспалительное средство для лечения контактного дерматита |
CN103251648B (zh) | 2013-05-15 | 2015-08-05 | 乔敏 | 治疗血磷酸盐过多症及缺铁性贫血症的铁基蒙脱石药物及其制备方法 |
WO2016051609A1 (ja) * | 2014-10-02 | 2016-04-07 | 東和薬品株式会社 | 粒度調整された炭酸ランタン水和物からなる医薬 |
CN104473963B (zh) * | 2014-12-24 | 2017-10-10 | 厦门科明达科技有限公司 | 稀土化学药碳酸镧咀嚼片的制备方法 |
US10058569B2 (en) * | 2015-06-24 | 2018-08-28 | Lupin Limited | Lanthanum carbonate compositions |
CN105125575B (zh) * | 2015-08-07 | 2018-06-08 | 康臣药业(内蒙古)有限责任公司 | 一种治疗高磷酸盐血症药物的制备方法 |
KR20180088821A (ko) | 2015-11-30 | 2018-08-07 | 도레이 카부시키가이샤 | 인 흡착제, 다공질 섬유 및 인 흡착 칼럼 |
CN114524452A (zh) * | 2017-10-30 | 2022-05-24 | 浙江大学 | 一种纳米碳酸镧水合物及其制备方法和应用 |
CN110579499A (zh) * | 2018-06-08 | 2019-12-17 | 北京华睿鼎信科技有限公司 | 一种碳酸镧或其制剂中碱式碳酸镧杂质的检定方法 |
CN112867695A (zh) * | 2018-10-26 | 2021-05-28 | 住友化学株式会社 | 水合碳酸镧的制造方法 |
CN111620363A (zh) * | 2020-06-13 | 2020-09-04 | 南京卡文迪许生物工程技术有限公司 | 一种四水合碳酸镧的制备方法及其产品 |
TW202202154A (zh) | 2020-07-13 | 2022-01-16 | 川口恒隆 | 含有鈰化合物作為有效成分之醫藥組成物以及氧化鈰微粒子之製造方法 |
CN114477265B (zh) * | 2020-11-13 | 2023-11-03 | 南京正济医药研究有限公司 | 一种四水碳酸镧的制备方法 |
CN115849429B (zh) * | 2023-01-06 | 2024-01-23 | 湖南明瑞制药股份有限公司 | 一种小粒径四水碳酸镧的制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06705B2 (ja) * | 1985-12-19 | 1994-01-05 | 旭化成工業株式会社 | リン酸イオンの固定化剤 |
-
1995
- 1995-03-25 GB GBGB9506126.3A patent/GB9506126D0/en active Pending
-
1996
- 1996-03-19 JP JP52904096A patent/JP3224544B2/ja not_active Expired - Lifetime
- 1996-03-19 DE DE122007000022C patent/DE122007000022I2/de active Active
- 1996-03-19 CN CN96193918A patent/CN1102393C/zh not_active Expired - Lifetime
- 1996-03-19 EA EA199700266A patent/EA000270B1/ru not_active IP Right Cessation
- 1996-03-19 DK DK96905960T patent/DK0817639T3/da active
- 1996-03-19 EP EP96905960A patent/EP0817639B1/en not_active Expired - Lifetime
- 1996-03-19 PL PL96322450A patent/PL184315B1/pl unknown
- 1996-03-19 KR KR1019970706684A patent/KR100329340B1/ko not_active IP Right Cessation
- 1996-03-19 AU AU49514/96A patent/AU702073B2/en not_active Ceased
- 1996-03-19 DE DE69617659T patent/DE69617659T4/de not_active Expired - Lifetime
- 1996-03-19 EE EE9700325A patent/EE04096B1/xx unknown
- 1996-03-19 TR TR97/01030T patent/TR199701030T1/xx unknown
- 1996-03-19 DE DE69617659A patent/DE69617659D1/de not_active Expired - Lifetime
- 1996-03-19 BR BR9607926A patent/BR9607926A/pt not_active IP Right Cessation
- 1996-03-19 US US08/913,960 patent/US5968976A/en not_active Expired - Lifetime
- 1996-03-19 ES ES96905960T patent/ES2170223T3/es not_active Expired - Lifetime
- 1996-03-19 HU HU9900799A patent/HU224198B1/hu active IP Right Grant
- 1996-03-19 NZ NZ303260A patent/NZ303260A/xx not_active IP Right Cessation
- 1996-03-19 SK SK1288-97A patent/SK282607B6/sk not_active IP Right Cessation
- 1996-03-19 WO PCT/GB1996/000575 patent/WO1996030029A1/en active IP Right Grant
- 1996-03-19 CZ CZ19973017A patent/CZ293494B6/cs not_active IP Right Cessation
- 1996-03-19 CA CA002216437A patent/CA2216437C/en not_active Expired - Lifetime
- 1996-03-19 PT PT96905960T patent/PT817639E/pt unknown
- 1996-03-19 DE DE1996617659 patent/DE122007000022I1/de active Pending
- 1996-03-19 AT AT96905960T patent/ATE209923T1/de active
- 1996-03-20 TW TW085103365A patent/TW436288B/zh not_active IP Right Cessation
- 1996-03-25 ZA ZA962369A patent/ZA962369B/xx unknown
-
1997
- 1997-09-24 NO NO19974425A patent/NO313488B1/no not_active IP Right Cessation
- 1997-09-25 MX MX9707334A patent/MX9707334A/es unknown
-
1998
- 1998-07-14 HK HK98109160A patent/HK1008182A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC4A | Registration of transfer of a eurasian patent by assignment | ||
MK4A | Patent expired |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |