HUP9802741A2 - Tiagabin-hidrokloridot tartalmazó gyógyszerkészítmény és eljárás annak előállítására - Google Patents

Tiagabin-hidrokloridot tartalmazó gyógyszerkészítmény és eljárás annak előállítására

Info

Publication number
HUP9802741A2
HUP9802741A2 HUP9802741A HUP9802741A2 HU P9802741 A2 HUP9802741 A2 HU P9802741A2 HU P9802741 A HUP9802741 A HU P9802741A HU P9802741 A2 HUP9802741 A2 HU P9802741A2
Authority
HU
Hungary
Prior art keywords
preparation
medicinally
pharmaceutical composition
composition containing
tiagabine hydrochloride
Prior art date
Application number
Other languages
English (en)
Inventor
Tina Meinertz Andersen
Thyge Borup Hjorth
Lars Nygaard
Jorgen Svensson
Helle Weibel
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of HUP9802741A2 publication Critical patent/HUP9802741A2/hu
Publication of HUP9802741A3 publication Critical patent/HUP9802741A3/hu
Publication of HU223075B1 publication Critical patent/HU223075B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

A találmány tárgya gyógyszerkészítmény, azzal jellemezve, hőgy (a) tiagabint vagy annak valamely gyógyászatilag elfőgadható sóját, (b) tiagabint vagy annak gyógyászatilag elfőgadható sóját kielégítőmennyiségben stabilizáló egy vagy több gyógyászatilag elfőgadhatóantiőxidánst, és (c) kívánt esetben valamely gyógyászatilag elfőgadható vívőanyagőttartalmaz. A találmány tárgya tővábbá eljárás a fenti gyógyszerkészítményelőállítására. A találmány szerinti gyógyszerkészítmény stabil és antiepileptikűsaktivitással rendelkezik. ŕ
HU9802741A 1995-05-05 1996-04-29 Tiagabint, illetve sóját tartalmazó gyógyszerkészítmény és eljárás annak előállítására HU223075B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK52395 1995-05-05
PCT/DK1996/000192 WO1996034606A1 (en) 1995-05-05 1996-04-29 Pharmaceutical composition containing tiagabine hydrochloride and the process for its preparation

Publications (3)

Publication Number Publication Date
HUP9802741A2 true HUP9802741A2 (hu) 1999-03-29
HUP9802741A3 HUP9802741A3 (en) 1999-04-28
HU223075B1 HU223075B1 (hu) 2004-03-01

Family

ID=8094516

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9802741A HU223075B1 (hu) 1995-05-05 1996-04-29 Tiagabint, illetve sóját tartalmazó gyógyszerkészítmény és eljárás annak előállítására

Country Status (26)

Country Link
US (1) US5866590A (hu)
EP (1) EP0830132B1 (hu)
JP (1) JP3195360B2 (hu)
KR (1) KR100440354B1 (hu)
CN (1) CN1092959C (hu)
AR (1) AR003418A1 (hu)
AT (1) ATE211911T1 (hu)
AU (1) AU707508B2 (hu)
BR (1) BR9608120A (hu)
CA (1) CA2220019C (hu)
CZ (1) CZ292256B6 (hu)
DE (1) DE69618586T2 (hu)
DK (1) DK0830132T3 (hu)
EG (1) EG23781A (hu)
ES (1) ES2171669T3 (hu)
HU (1) HU223075B1 (hu)
IL (1) IL118142A (hu)
MX (1) MX9708394A (hu)
MY (1) MY115016A (hu)
NO (1) NO318599B1 (hu)
NZ (1) NZ307159A (hu)
PL (1) PL183678B1 (hu)
PT (1) PT830132E (hu)
UA (1) UA43402C2 (hu)
WO (1) WO1996034606A1 (hu)
ZA (1) ZA963478B (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5914333A (en) * 1996-07-31 1999-06-22 Novo Nordisk A/S Treatment of psychotic disorders
DE69803670T2 (de) * 1997-08-01 2002-11-21 Elan Corp Plc Dublin Tiagabinhaltige arzneizubereitungen mit gesteuerter wirkstoffverabreichung
IE970588A1 (en) 1997-08-01 2000-08-23 Elan Corp Plc Controlled release pharmaceutical compositions containing tiagabine
EP1017386A1 (en) * 1997-10-02 2000-07-12 H. Lundbeck A/S GRANULAR PREPARATIONS OF 5-(2-ETHYL- 2$i(H)-TETRAZOL- 5-YL)-1-METHYL-1, 2,3,6-TETRAHYDROPYRIDINE
FR2771292B1 (fr) * 1997-11-21 2000-02-18 Ethypharm Lab Prod Ethiques Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques
ZA99407B (en) * 1998-01-22 1999-07-20 Abbott Lab Extended release tiagabine formulations with reduced side-effects.
AU2002325404B2 (en) * 1998-01-22 2006-02-02 Abbott Laboratories Extended Release Tiagabine Formulations with Reduced Side-effects
WO2001091751A1 (en) * 2000-05-30 2001-12-06 Novo Nordisk A/S New pharmaceutical composition and the process for its preparation
JP2004506609A (ja) * 2000-05-26 2004-03-04 ノボ　ノルディスク　アクティーゼルスカブ 新たなる医薬組成物及びその調製の為の方法
WO2006067605A1 (en) * 2004-12-23 2006-06-29 Ranbaxy Laboratories Limited Stable pharmaceutical compositions of tiagabine and processes for their preparation
CN102125693A (zh) * 2011-01-25 2011-07-20 福建科瑞药业有限公司 一种盐酸噻加宾药物组合物及其制备方法
CA2873016A1 (en) * 2012-05-08 2013-11-14 Cellixbio Private Limited Compositions and methods for the treatment of epilepsy
WO2017038612A1 (ja) * 2015-08-28 2017-03-09 日本化薬株式会社 ラパマイシン又はその誘導体を含有する医薬組成物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US501090A (en) * 1893-07-11 gennert
DK288385D0 (da) * 1985-06-26 1985-06-26 Novo Industri As Aminosyrederivater
DK58291D0 (da) * 1991-04-02 1991-04-02 Novo Nordisk As Krystalinsk stof og dets fremstilling
WO1995005808A1 (en) * 1993-08-24 1995-03-02 Abbott Laboratories Oil-based tableting method
ZA953078B (en) * 1994-04-28 1996-01-05 Alza Corp Effective therapy for epilepsies

Also Published As

Publication number Publication date
ATE211911T1 (de) 2002-02-15
CN1183721A (zh) 1998-06-03
US5866590A (en) 1999-02-02
CZ292256B6 (cs) 2003-08-13
PT830132E (pt) 2002-07-31
NZ307159A (en) 1998-10-28
AU707508B2 (en) 1999-07-15
NO975076D0 (no) 1997-11-04
KR100440354B1 (ko) 2004-09-18
JP3195360B2 (ja) 2001-08-06
CN1092959C (zh) 2002-10-23
EG23781A (en) 2007-08-13
BR9608120A (pt) 1999-02-09
UA43402C2 (uk) 2001-12-17
HU223075B1 (hu) 2004-03-01
ES2171669T3 (es) 2002-09-16
CA2220019C (en) 2007-12-11
JPH10505359A (ja) 1998-05-26
WO1996034606A1 (en) 1996-11-07
EP0830132B1 (en) 2002-01-16
MY115016A (en) 2003-03-31
IL118142A0 (en) 1996-09-12
CZ338897A3 (cs) 1998-03-18
DE69618586T2 (de) 2002-09-05
EP0830132A1 (en) 1998-03-25
DE69618586D1 (de) 2002-02-21
IL118142A (en) 1999-11-30
AU5644196A (en) 1996-11-21
DK0830132T3 (da) 2002-04-29
PL323138A1 (en) 1998-03-16
ZA963478B (en) 1996-11-13
NO318599B1 (no) 2005-04-18
HUP9802741A3 (en) 1999-04-28
PL183678B1 (pl) 2002-06-28
CA2220019A1 (en) 1996-11-07
NO975076L (no) 1997-11-04
AR003418A1 (es) 1998-08-05
MX9708394A (es) 1998-02-28

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Legal Events

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HFG4 Patent granted, date of granting

Effective date: 20040114

MM4A Lapse of definitive patent protection due to non-payment of fees