HUP9802492A3 - Benzisoxazole and indazole derivatives as antipsychotic agents, process for their preparation and pharmaceutical compositions containing the same - Google Patents
Benzisoxazole and indazole derivatives as antipsychotic agents, process for their preparation and pharmaceutical compositions containing the sameInfo
- Publication number
- HUP9802492A3 HUP9802492A3 HU9802492A HUP9802492A HUP9802492A3 HU P9802492 A3 HUP9802492 A3 HU P9802492A3 HU 9802492 A HU9802492 A HU 9802492A HU P9802492 A HUP9802492 A HU P9802492A HU P9802492 A3 HUP9802492 A3 HU P9802492A3
- Authority
- HU
- Hungary
- Prior art keywords
- benzisoxazole
- preparation
- pharmaceutical compositions
- same
- compositions containing
- Prior art date
Links
- KTZQTRPPVKQPFO-UHFFFAOYSA-N 1,2-benzoxazole Chemical compound C1=CC=C2C=NOC2=C1 KTZQTRPPVKQPFO-UHFFFAOYSA-N 0.000 title 1
- 239000000164 antipsychotic agent Substances 0.000 title 1
- 125000003453 indazolyl group Chemical class N1N=C(C2=C1C=CC=C2)* 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47040095A | 1995-06-06 | 1995-06-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9802492A2 HUP9802492A2 (hu) | 1999-09-28 |
| HUP9802492A3 true HUP9802492A3 (en) | 1999-10-28 |
Family
ID=23867483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9802492A HUP9802492A3 (en) | 1995-06-06 | 1996-05-14 | Benzisoxazole and indazole derivatives as antipsychotic agents, process for their preparation and pharmaceutical compositions containing the same |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US5696113A (hu) |
| EP (1) | EP0833820B1 (hu) |
| JP (2) | JP3122469B2 (hu) |
| KR (1) | KR100304179B1 (hu) |
| AR (1) | AR002300A1 (hu) |
| AT (1) | ATE199147T1 (hu) |
| AU (1) | AU697953B2 (hu) |
| CA (1) | CA2218663C (hu) |
| DE (1) | DE69611783T2 (hu) |
| DK (1) | DK0833820T3 (hu) |
| ES (1) | ES2157442T3 (hu) |
| GR (1) | GR3035663T3 (hu) |
| HU (1) | HUP9802492A3 (hu) |
| IL (1) | IL118530A0 (hu) |
| MX (1) | MX9709451A (hu) |
| NO (1) | NO975681L (hu) |
| NZ (1) | NZ307958A (hu) |
| PT (1) | PT833820E (hu) |
| WO (2) | WO1996039397A1 (hu) |
| ZA (1) | ZA964562B (hu) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6008348A (en) * | 1995-06-06 | 1999-12-28 | Hoechst Marion Roussel, Inc. | Antipsychotic agents, compositions and method of use |
| TW487572B (en) * | 1996-05-20 | 2002-05-21 | Janssen Pharmaceutica Nv | Aqueous suspensions of 9-hydroxyrisperidone fatty acid esters |
| UA72189C2 (uk) | 1997-11-17 | 2005-02-15 | Янссен Фармацевтика Н.В. | Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот |
| US7091199B1 (en) | 1999-09-14 | 2006-08-15 | Aventis Pharmaceuticals Inc. | Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists |
| US7253165B2 (en) * | 1999-09-14 | 2007-08-07 | Aventis Pharmaceuticals Inc. | Benzisoxazolyl-, pyridoisoxazolyl-and benzthienyl-phenoxy derivatives useful as D4 antagonists |
| US7125903B1 (en) * | 1999-09-14 | 2006-10-24 | Aventis Pharmaceuticals Inc. | Thienoisoxazolyl-and thienylpyrrazolyl-phenoxy substituted propyl derivatives useful as D4 antagonists |
| GB0117531D0 (en) * | 2001-02-16 | 2001-09-12 | Aventis Pharm Prod Inc | Novel heterocyclic amide derivatives and their use as dopamine D3 receptor ligands |
| KR100627031B1 (ko) * | 2004-09-04 | 2006-09-21 | 주식회사 케이티프리텔 | 등산 정보 서비스 제공 방법 및 장치 |
| DE102005038947A1 (de) * | 2005-05-18 | 2006-11-30 | Grünenthal GmbH | Substituierte Benzo[d]isoxazol-3-yl-amin-Verbindungen und deren Verwendung in Arzneimitteln |
| KR100673033B1 (ko) * | 2005-06-21 | 2007-01-22 | (주) 엘지텔레콤 | 레저 전용 휴대 단말기 |
| JP2010519171A (ja) | 2006-02-17 | 2010-06-03 | メモリー・ファーマシューティカルズ・コーポレイション | ５−ｈｔ６受容体親和性を有する化合物 |
| KR20110076944A (ko) * | 2008-09-23 | 2011-07-06 | 에프. 호프만-라 로슈 아게 | 도파민 ｄ3 수용체의 조절제로서 유용한 이속사졸로〔4,5〕피리딘-3-일-피페라진 유도체 |
| AR077033A1 (es) * | 2009-06-11 | 2011-07-27 | Hoffmann La Roche | Compuestos inhibidores de las quinasas de janus y su uso en el tratamiento de enfermedades inmunologicas |
| CN110117278B (zh) * | 2018-02-07 | 2022-07-19 | 石家庄以岭药业股份有限公司 | 烷氧基苯并五元(六元)杂环胺类化合物及其药物用途 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4411901A (en) * | 1981-12-23 | 1983-10-25 | Mead Johnson & Company | Benzisothiazole and benzisoxazole piperazine derivatives |
| US4806649A (en) * | 1983-08-22 | 1989-02-21 | Hoechst-Roussel Pharmaceuticals, Inc. | 3-(piperidinyl)- and 3- (pyrrolidinyl)-1H-indazoles |
| US4853470A (en) * | 1983-08-22 | 1989-08-01 | Hoechst-Roussel Pharmaceuticals, Inc. | 3-(piperidinyl)- and 3-(pyrrolidinyl)-1H-indazoles |
| US4670447A (en) * | 1983-08-22 | 1987-06-02 | Hoechst-Roussel Pharmaceuticals Inc. | Antipsychotic 3-(piperidinyl)- and 3-(pyrrolidinyl)-1H-indazoles |
| US4590196A (en) * | 1984-08-23 | 1986-05-20 | Bristol-Myers Company | Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives |
| MX174210B (es) * | 1987-02-17 | 1994-04-28 | Pfizer | Procedimiento para la preparacion de compuestos arilpiperazinil-alquilenfenil-p-heterociclicos |
| EP0302423A3 (en) * | 1987-08-07 | 1991-01-09 | Hoechst-Roussel Pharmaceuticals Incorporated | 1-phenyl-3-(1-piperazinyl)-1h-indazoles, a process and intermediates for their preparation, and the use thereof as medicaments |
| NZ233525A (en) * | 1989-05-15 | 1991-09-25 | Janssen Pharmaceutica Nv | Piperidinyl, pyrrolidinyl and piperazinyl alkylphenol ethers and pharmaceutical compositions |
| ATE126512T1 (de) * | 1989-05-19 | 1995-09-15 | Hoechst Roussel Pharma | N-(aryloxyalkyl)heteroarylpiperidine und - heteroarylpiperazine, verfahren zu ihrer herstellung und ihre verwendung als medikamente. |
| US5364866A (en) * | 1989-05-19 | 1994-11-15 | Hoechst-Roussel Pharmaceuticals, Inc. | Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics |
| US5077405A (en) * | 1989-09-11 | 1991-12-31 | Hoechst-Roussel Pharmaceuticals Incorporated | 3-(1-Substituted-4-piperazinyl)-1H-indazoles |
| US4954503A (en) * | 1989-09-11 | 1990-09-04 | Hoechst-Roussel Pharmaceuticals, Inc. | 3-(1-substituted-4-piperazinyl)-1H-indazoles |
| FR2671350A1 (fr) * | 1991-01-08 | 1992-07-10 | Adir | Nouveaux derives de benzisoxazole et de benzisothiazole, leur procede de preparation, et les compositions pharmaceutiques les renfermant. |
| BR9205811A (pt) * | 1991-03-28 | 1994-06-28 | Pfizer | Derivados heterociclicos de aminas ciclicas |
| US5328920A (en) * | 1991-04-17 | 1994-07-12 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted (pyridinylamino)-indoles |
| US5177088A (en) * | 1991-04-17 | 1993-01-05 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted 3-(pyridinylamino)-indoles |
| US5206366A (en) * | 1992-08-26 | 1993-04-27 | Pfizer Inc. | Process for preparing aryl piperazinyl-heterocyclic compounds |
| US5494908A (en) * | 1992-11-23 | 1996-02-27 | Hoechst-Roussel Pharmaceutical Incorporated | Substituted 3-(aminoalkylamino)-1,2-benzisoxazoles and related compounds |
-
1996
- 1996-05-14 KR KR1019970708743A patent/KR100304179B1/ko not_active IP Right Cessation
- 1996-05-14 WO PCT/US1996/006851 patent/WO1996039397A1/en active IP Right Grant
- 1996-05-14 PT PT96915782T patent/PT833820E/pt unknown
- 1996-05-14 DK DK96915782T patent/DK0833820T3/da active
- 1996-05-14 HU HU9802492A patent/HUP9802492A3/hu unknown
- 1996-05-14 DE DE69611783T patent/DE69611783T2/de not_active Expired - Fee Related
- 1996-05-14 AU AU57464/96A patent/AU697953B2/en not_active Ceased
- 1996-05-14 JP JP09500630A patent/JP3122469B2/ja not_active Expired - Fee Related
- 1996-05-14 NZ NZ307958A patent/NZ307958A/xx unknown
- 1996-05-14 EP EP96915782A patent/EP0833820B1/en not_active Expired - Lifetime
- 1996-05-14 AT AT96915782T patent/ATE199147T1/de not_active IP Right Cessation
- 1996-05-14 ES ES96915782T patent/ES2157442T3/es not_active Expired - Lifetime
- 1996-05-14 WO PCT/US1996/007319 patent/WO1996039405A1/en not_active Application Discontinuation
- 1996-05-14 MX MX9709451A patent/MX9709451A/es unknown
- 1996-05-14 CA CA002218663A patent/CA2218663C/en not_active Expired - Fee Related
- 1996-05-14 JP JP9500561A patent/JP3057763B2/ja not_active Expired - Fee Related
- 1996-06-02 IL IL11853096A patent/IL118530A0/xx unknown
- 1996-06-03 ZA ZA964562A patent/ZA964562B/xx unknown
- 1996-06-04 AR ARP960102884A patent/AR002300A1/es unknown
- 1996-06-27 US US08/672,127 patent/US5696113A/en not_active Expired - Fee Related
-
1997
- 1997-09-02 US US08/921,480 patent/US5852022A/en not_active Expired - Fee Related
- 1997-12-05 NO NO975681A patent/NO975681L/no not_active Application Discontinuation
-
1998
- 1998-09-11 US US09/150,971 patent/US5965554A/en not_active Expired - Fee Related
-
2001
- 2001-03-29 GR GR20010400513T patent/GR3035663T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP3122469B2 (ja) | 2001-01-09 |
| CA2218663C (en) | 2001-07-31 |
| JPH11507030A (ja) | 1999-06-22 |
| MX9709451A (es) | 1998-02-28 |
| JP3057763B2 (ja) | 2000-07-04 |
| AR002300A1 (es) | 1998-03-11 |
| DE69611783D1 (de) | 2001-03-22 |
| WO1996039405A1 (en) | 1996-12-12 |
| WO1996039397A1 (en) | 1996-12-12 |
| HUP9802492A2 (hu) | 1999-09-28 |
| US5965554A (en) | 1999-10-12 |
| US5696113A (en) | 1997-12-09 |
| PT833820E (pt) | 2001-07-31 |
| NZ307958A (en) | 1999-02-25 |
| KR19990022264A (ko) | 1999-03-25 |
| GR3035663T3 (en) | 2001-06-29 |
| KR100304179B1 (ko) | 2001-11-22 |
| CA2218663A1 (en) | 1996-12-12 |
| JPH11506728A (ja) | 1999-06-15 |
| NO975681D0 (no) | 1997-12-05 |
| AU697953B2 (en) | 1998-10-22 |
| ATE199147T1 (de) | 2001-02-15 |
| DK0833820T3 (da) | 2001-04-17 |
| EP0833820A1 (en) | 1998-04-08 |
| AU5746496A (en) | 1996-12-24 |
| US5852022A (en) | 1998-12-22 |
| ZA964562B (en) | 1996-12-12 |
| EP0833820B1 (en) | 2001-02-14 |
| DE69611783T2 (de) | 2001-09-20 |
| ES2157442T3 (es) | 2001-08-16 |
| NO975681L (no) | 1998-02-05 |
| IL118530A0 (en) | 1996-10-16 |
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