DK0833820T3 - Benzisoxazol- og indazolderivater som antipsykotiske midler - Google Patents
Benzisoxazol- og indazolderivater som antipsykotiske midlerInfo
- Publication number
- DK0833820T3 DK0833820T3 DK96915782T DK96915782T DK0833820T3 DK 0833820 T3 DK0833820 T3 DK 0833820T3 DK 96915782 T DK96915782 T DK 96915782T DK 96915782 T DK96915782 T DK 96915782T DK 0833820 T3 DK0833820 T3 DK 0833820T3
- Authority
- DK
- Denmark
- Prior art keywords
- benzisoxazole
- antipsychotic agents
- indazole derivatives
- indazole
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47040095A | 1995-06-06 | 1995-06-06 | |
| PCT/US1996/006851 WO1996039397A1 (en) | 1995-06-06 | 1996-05-14 | Benzisoxazole and indazole derivatives as antipsychotic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0833820T3 true DK0833820T3 (da) | 2001-04-17 |
Family
ID=23867483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96915782T DK0833820T3 (da) | 1995-06-06 | 1996-05-14 | Benzisoxazol- og indazolderivater som antipsykotiske midler |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US5696113A (da) |
| EP (1) | EP0833820B1 (da) |
| JP (2) | JP3057763B2 (da) |
| KR (1) | KR100304179B1 (da) |
| AR (1) | AR002300A1 (da) |
| AT (1) | ATE199147T1 (da) |
| AU (1) | AU697953B2 (da) |
| CA (1) | CA2218663C (da) |
| DE (1) | DE69611783T2 (da) |
| DK (1) | DK0833820T3 (da) |
| ES (1) | ES2157442T3 (da) |
| GR (1) | GR3035663T3 (da) |
| HU (1) | HUP9802492A3 (da) |
| IL (1) | IL118530A0 (da) |
| MX (1) | MX9709451A (da) |
| NO (1) | NO975681L (da) |
| NZ (1) | NZ307958A (da) |
| PT (1) | PT833820E (da) |
| WO (2) | WO1996039405A1 (da) |
| ZA (1) | ZA964562B (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6008348A (en) * | 1995-06-06 | 1999-12-28 | Hoechst Marion Roussel, Inc. | Antipsychotic agents, compositions and method of use |
| TW487572B (en) * | 1996-05-20 | 2002-05-21 | Janssen Pharmaceutica Nv | Aqueous suspensions of 9-hydroxyrisperidone fatty acid esters |
| UA72189C2 (uk) | 1997-11-17 | 2005-02-15 | Янссен Фармацевтика Н.В. | Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот |
| US7091199B1 (en) | 1999-09-14 | 2006-08-15 | Aventis Pharmaceuticals Inc. | Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists |
| US7253165B2 (en) * | 1999-09-14 | 2007-08-07 | Aventis Pharmaceuticals Inc. | Benzisoxazolyl-, pyridoisoxazolyl-and benzthienyl-phenoxy derivatives useful as D4 antagonists |
| US7125903B1 (en) * | 1999-09-14 | 2006-10-24 | Aventis Pharmaceuticals Inc. | Thienoisoxazolyl-and thienylpyrrazolyl-phenoxy substituted propyl derivatives useful as D4 antagonists |
| GB0117531D0 (en) * | 2001-02-16 | 2001-09-12 | Aventis Pharm Prod Inc | Novel heterocyclic amide derivatives and their use as dopamine D3 receptor ligands |
| KR100627031B1 (ko) * | 2004-09-04 | 2006-09-21 | 주식회사 케이티프리텔 | 등산 정보 서비스 제공 방법 및 장치 |
| DE102005038947A1 (de) * | 2005-05-18 | 2006-11-30 | Grünenthal GmbH | Substituierte Benzo[d]isoxazol-3-yl-amin-Verbindungen und deren Verwendung in Arzneimitteln |
| KR100673033B1 (ko) * | 2005-06-21 | 2007-01-22 | (주) 엘지텔레콤 | 레저 전용 휴대 단말기 |
| CA2637531A1 (en) | 2006-02-17 | 2007-08-30 | Memory Pharmaceuticals Corporation | Compounds having 5-ht6 receptor affinity |
| CN102164927A (zh) * | 2008-09-23 | 2011-08-24 | 弗·哈夫曼-拉罗切有限公司 | 用作多巴胺d3受体调节剂的异唑并[4,5]吡啶-3-基-哌嗪衍生物 |
| AR077033A1 (es) * | 2009-06-11 | 2011-07-27 | Hoffmann La Roche | Compuestos inhibidores de las quinasas de janus y su uso en el tratamiento de enfermedades inmunologicas |
| CN110117278B (zh) * | 2018-02-07 | 2022-07-19 | 石家庄以岭药业股份有限公司 | 烷氧基苯并五元(六元)杂环胺类化合物及其药物用途 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4411901A (en) * | 1981-12-23 | 1983-10-25 | Mead Johnson & Company | Benzisothiazole and benzisoxazole piperazine derivatives |
| US4806649A (en) * | 1983-08-22 | 1989-02-21 | Hoechst-Roussel Pharmaceuticals, Inc. | 3-(piperidinyl)- and 3- (pyrrolidinyl)-1H-indazoles |
| US4853470A (en) * | 1983-08-22 | 1989-08-01 | Hoechst-Roussel Pharmaceuticals, Inc. | 3-(piperidinyl)- and 3-(pyrrolidinyl)-1H-indazoles |
| US4670447A (en) * | 1983-08-22 | 1987-06-02 | Hoechst-Roussel Pharmaceuticals Inc. | Antipsychotic 3-(piperidinyl)- and 3-(pyrrolidinyl)-1H-indazoles |
| US4590196A (en) * | 1984-08-23 | 1986-05-20 | Bristol-Myers Company | Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives |
| MX174210B (es) * | 1987-02-17 | 1994-04-28 | Pfizer | Procedimiento para la preparacion de compuestos arilpiperazinil-alquilenfenil-p-heterociclicos |
| EP0302423A3 (en) * | 1987-08-07 | 1991-01-09 | Hoechst-Roussel Pharmaceuticals Incorporated | 1-phenyl-3-(1-piperazinyl)-1h-indazoles, a process and intermediates for their preparation, and the use thereof as medicaments |
| NZ233525A (en) * | 1989-05-15 | 1991-09-25 | Janssen Pharmaceutica Nv | Piperidinyl, pyrrolidinyl and piperazinyl alkylphenol ethers and pharmaceutical compositions |
| ES2076253T3 (es) * | 1989-05-19 | 1995-11-01 | Hoechst Roussel Pharma | N-(ariloxialquil)-heteroarilpiperidinas y -heteroarilpiperazinas, un procedimiento para su preparacion y su uso como medicamentos. |
| US5364866A (en) * | 1989-05-19 | 1994-11-15 | Hoechst-Roussel Pharmaceuticals, Inc. | Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics |
| US5077405A (en) * | 1989-09-11 | 1991-12-31 | Hoechst-Roussel Pharmaceuticals Incorporated | 3-(1-Substituted-4-piperazinyl)-1H-indazoles |
| US4954503A (en) * | 1989-09-11 | 1990-09-04 | Hoechst-Roussel Pharmaceuticals, Inc. | 3-(1-substituted-4-piperazinyl)-1H-indazoles |
| FR2671350A1 (fr) * | 1991-01-08 | 1992-07-10 | Adir | Nouveaux derives de benzisoxazole et de benzisothiazole, leur procede de preparation, et les compositions pharmaceutiques les renfermant. |
| CZ289756B6 (cs) * | 1991-03-28 | 2002-04-17 | Eisai Co., Ltd. | Heterocyklicko-cyklické aminové deriváty, meziprodukty postupu přípravy těchto sloučenin, farmaceutický prostředek a pouľití uvedených derivátů |
| US5328920A (en) * | 1991-04-17 | 1994-07-12 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted (pyridinylamino)-indoles |
| US5177088A (en) * | 1991-04-17 | 1993-01-05 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted 3-(pyridinylamino)-indoles |
| US5206366A (en) * | 1992-08-26 | 1993-04-27 | Pfizer Inc. | Process for preparing aryl piperazinyl-heterocyclic compounds |
| US5494908A (en) * | 1992-11-23 | 1996-02-27 | Hoechst-Roussel Pharmaceutical Incorporated | Substituted 3-(aminoalkylamino)-1,2-benzisoxazoles and related compounds |
-
1996
- 1996-05-14 DE DE69611783T patent/DE69611783T2/de not_active Expired - Fee Related
- 1996-05-14 PT PT96915782T patent/PT833820E/pt unknown
- 1996-05-14 KR KR1019970708743A patent/KR100304179B1/ko not_active IP Right Cessation
- 1996-05-14 WO PCT/US1996/007319 patent/WO1996039405A1/en not_active Application Discontinuation
- 1996-05-14 JP JP9500561A patent/JP3057763B2/ja not_active Expired - Fee Related
- 1996-05-14 NZ NZ307958A patent/NZ307958A/xx unknown
- 1996-05-14 EP EP96915782A patent/EP0833820B1/en not_active Expired - Lifetime
- 1996-05-14 DK DK96915782T patent/DK0833820T3/da active
- 1996-05-14 JP JP09500630A patent/JP3122469B2/ja not_active Expired - Fee Related
- 1996-05-14 WO PCT/US1996/006851 patent/WO1996039397A1/en active IP Right Grant
- 1996-05-14 HU HU9802492A patent/HUP9802492A3/hu unknown
- 1996-05-14 AU AU57464/96A patent/AU697953B2/en not_active Ceased
- 1996-05-14 AT AT96915782T patent/ATE199147T1/de not_active IP Right Cessation
- 1996-05-14 CA CA002218663A patent/CA2218663C/en not_active Expired - Fee Related
- 1996-05-14 ES ES96915782T patent/ES2157442T3/es not_active Expired - Lifetime
- 1996-05-14 MX MX9709451A patent/MX9709451A/es unknown
- 1996-06-02 IL IL11853096A patent/IL118530A0/xx unknown
- 1996-06-03 ZA ZA964562A patent/ZA964562B/xx unknown
- 1996-06-04 AR ARP960102884A patent/AR002300A1/es unknown
- 1996-06-27 US US08/672,127 patent/US5696113A/en not_active Expired - Fee Related
-
1997
- 1997-09-02 US US08/921,480 patent/US5852022A/en not_active Expired - Fee Related
- 1997-12-05 NO NO975681A patent/NO975681L/no not_active Application Discontinuation
-
1998
- 1998-09-11 US US09/150,971 patent/US5965554A/en not_active Expired - Fee Related
-
2001
- 2001-03-29 GR GR20010400513T patent/GR3035663T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU697953B2 (en) | 1998-10-22 |
| EP0833820B1 (en) | 2001-02-14 |
| DE69611783T2 (de) | 2001-09-20 |
| JPH11507030A (ja) | 1999-06-22 |
| PT833820E (pt) | 2001-07-31 |
| WO1996039397A1 (en) | 1996-12-12 |
| HUP9802492A2 (hu) | 1999-09-28 |
| WO1996039405A1 (en) | 1996-12-12 |
| NZ307958A (en) | 1999-02-25 |
| DE69611783D1 (de) | 2001-03-22 |
| EP0833820A1 (en) | 1998-04-08 |
| HUP9802492A3 (en) | 1999-10-28 |
| NO975681L (no) | 1998-02-05 |
| AR002300A1 (es) | 1998-03-11 |
| ZA964562B (en) | 1996-12-12 |
| US5696113A (en) | 1997-12-09 |
| AU5746496A (en) | 1996-12-24 |
| ES2157442T3 (es) | 2001-08-16 |
| KR100304179B1 (ko) | 2001-11-22 |
| CA2218663A1 (en) | 1996-12-12 |
| NO975681D0 (no) | 1997-12-05 |
| US5965554A (en) | 1999-10-12 |
| IL118530A0 (en) | 1996-10-16 |
| US5852022A (en) | 1998-12-22 |
| JP3122469B2 (ja) | 2001-01-09 |
| GR3035663T3 (en) | 2001-06-29 |
| MX9709451A (es) | 1998-02-28 |
| KR19990022264A (ko) | 1999-03-25 |
| CA2218663C (en) | 2001-07-31 |
| ATE199147T1 (de) | 2001-02-15 |
| JP3057763B2 (ja) | 2000-07-04 |
| JPH11506728A (ja) | 1999-06-15 |
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