HUP9801687A2 - Eljárás nukleinsavak előállítására - Google Patents
Eljárás nukleinsavak előállításáraInfo
- Publication number
- HUP9801687A2 HUP9801687A2 HU9801687A HUP9801687A HUP9801687A2 HU P9801687 A2 HUP9801687 A2 HU P9801687A2 HU 9801687 A HU9801687 A HU 9801687A HU P9801687 A HUP9801687 A HU P9801687A HU P9801687 A2 HUP9801687 A2 HU P9801687A2
- Authority
- HU
- Hungary
- Prior art keywords
- acid
- inosine
- protein
- guanosine
- microorganisms
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- NYHBQMYGNKIUIF-UUOKFMHZSA-N Guanosine Chemical compound C1=NC=2C(=O)NC(N)=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O NYHBQMYGNKIUIF-UUOKFMHZSA-N 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- ZKHQWZAMYRWXGA-KQYNXXCUSA-J ATP(4-) Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O ZKHQWZAMYRWXGA-KQYNXXCUSA-J 0.000 abstract 2
- ZKHQWZAMYRWXGA-UHFFFAOYSA-N Adenosine triphosphate Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C1O ZKHQWZAMYRWXGA-UHFFFAOYSA-N 0.000 abstract 2
- MIKUYHXYGGJMLM-GIMIYPNGSA-N Crotonoside Natural products C1=NC2=C(N)NC(=O)N=C2N1[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O MIKUYHXYGGJMLM-GIMIYPNGSA-N 0.000 abstract 2
- NYHBQMYGNKIUIF-UHFFFAOYSA-N D-guanosine Natural products C1=2NC(N)=NC(=O)C=2N=CN1C1OC(CO)C(O)C1O NYHBQMYGNKIUIF-UHFFFAOYSA-N 0.000 abstract 2
- 108020004414 DNA Proteins 0.000 abstract 2
- UGQMRVRMYYASKQ-KQYNXXCUSA-N Inosine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C2=NC=NC(O)=C2N=C1 UGQMRVRMYYASKQ-KQYNXXCUSA-N 0.000 abstract 2
- 229930010555 Inosine Natural products 0.000 abstract 2
- 229940029575 guanosine Drugs 0.000 abstract 2
- 229960003786 inosine Drugs 0.000 abstract 2
- 244000005700 microbiome Species 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- RQFCJASXJCIDSX-UHFFFAOYSA-N 14C-Guanosin-5'-monophosphat Natural products C1=2NC(N)=NC(=O)C=2N=CN1C1OC(COP(O)(O)=O)C(O)C1O RQFCJASXJCIDSX-UHFFFAOYSA-N 0.000 abstract 1
- GRSZFWQUAKGDAV-KQYNXXCUSA-N IMP Chemical compound O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N1C(NC=NC2=O)=C2N=C1 GRSZFWQUAKGDAV-KQYNXXCUSA-N 0.000 abstract 1
- 108010001139 Inosine kinase Proteins 0.000 abstract 1
- GRSZFWQUAKGDAV-UHFFFAOYSA-N Inosinic acid Natural products OC1C(O)C(COP(O)(O)=O)OC1N1C(NC=NC2=O)=C2N=C1 GRSZFWQUAKGDAV-UHFFFAOYSA-N 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 235000013355 food flavoring agent Nutrition 0.000 abstract 1
- RQFCJASXJCIDSX-UUOKFMHZSA-N guanosine 5'-monophosphate Chemical compound C1=2NC(N)=NC(=O)C=2N=CN1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O RQFCJASXJCIDSX-UUOKFMHZSA-N 0.000 abstract 1
- 235000013928 guanylic acid Nutrition 0.000 abstract 1
- 235000013902 inosinic acid Nutrition 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
A találmány tárgya eljárás 5'-inőzinsav és 5'-gűanilsav - melyekízesítőként vagy ehhez hasőnló módőn alkalmazhatóak - előállítására,inőzinból, gűanőzinból vagy ezek előanyagaiból kiindűlva, őlyanadenőzin-trifőszfátőt (ATP-t) termelő mikrőőrganizműsőkalkalmazásával, amelyek inőzinból vagy gűanőzinból 5'-inőzinsavat vagy5'-gűanilsavat előállítani képes fehérjét kódőló DNS-t tartalmaznak. A találmány tárgyát képezik tővábbá egy új fehérje, amely inőzin-gűanőzin kináz aktivitású, egy gén, amely ezt a fehérjét kódőlja,rekőmbináns DNS, amely a gént tartalmazza és mikrőőrganizműsők, melyeka rekőmbináns DNS-sel vannak transzfőrmálva. A találmány szerinti eljárás alkalmas 5'-inőzinsav és 5'gűanilsavipari előállítására. ŕ
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10288895 | 1995-03-24 | ||
| JP17790095 | 1995-06-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9801687A2 true HUP9801687A2 (hu) | 1998-10-28 |
| HUP9801687A3 HUP9801687A3 (en) | 2000-06-28 |
Family
ID=26443578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9801687A HUP9801687A3 (en) | 1995-03-24 | 1996-03-22 | Process for producing nucleic acids |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6673576B1 (hu) |
| EP (1) | EP0816491B1 (hu) |
| JP (1) | JP3948027B2 (hu) |
| KR (1) | KR100376635B1 (hu) |
| CN (1) | CN1130457C (hu) |
| BR (1) | BR9607745A (hu) |
| CA (1) | CA2216172A1 (hu) |
| DE (1) | DE69637616D1 (hu) |
| ES (1) | ES2311289T3 (hu) |
| HU (1) | HUP9801687A3 (hu) |
| PL (1) | PL184520B1 (hu) |
| WO (1) | WO1996030501A1 (hu) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100463983B1 (ko) * | 1998-03-14 | 2005-06-02 | 씨제이 주식회사 | 유전자 재조합 미생물에 의한 5'-구아닐산의 제조방법 |
| TWI222464B (en) * | 1999-02-08 | 2004-10-21 | Kyowa Hakko Kogyo Kk | Process for producing purine nucleotides |
| KR100397321B1 (ko) * | 2000-12-26 | 2003-09-06 | 씨제이 주식회사 | 5'-이노신산을 고수율로 생산하는 미생물 코리네박테리움암모니아게네스 씨제이아이피009 및 그를 이용한5'-이노신산 생산방법 |
| KR101089559B1 (ko) * | 2004-03-31 | 2011-12-06 | 아지노모토 가부시키가이샤 | 바실러스 또는 에스케리키아 속에 속하는 세균을 사용하여 발효에 의해 퓨린 뉴클레오사이드 및 뉴클레오타이드를 제조하는 방법 |
| KR100694427B1 (ko) * | 2005-12-02 | 2007-03-12 | 씨제이 주식회사 | 코리네박테리움 속 미생물 및 이를 이용한 5'-이노신산의제조 방법 |
| BRPI0710752B1 (pt) | 2006-04-24 | 2017-01-24 | Ajinomoto Kk | métodos para produzir uma substância derivada de purina e um nucleotídeo de purina |
| EP2011861A1 (en) | 2006-04-24 | 2009-01-07 | Ajinomoto Co., Inc. | Bacterium capable of producing purine substance, and process for production of purine substance |
| JP2010110216A (ja) | 2007-02-20 | 2010-05-20 | Ajinomoto Co Inc | Ｌ−アミノ酸または核酸の製造方法 |
| JP2011067095A (ja) | 2008-01-10 | 2011-04-07 | Ajinomoto Co Inc | 発酵法による目的物質の製造法 |
| CN101960005B (zh) | 2008-02-25 | 2016-02-24 | 味之素株式会社 | 5’-鸟苷酸的生产方法 |
| WO2010045326A1 (en) | 2008-10-14 | 2010-04-22 | Barnes Wayne M | In vitro recombination methods using 5' exonuclease |
| JP6519476B2 (ja) | 2013-10-23 | 2019-05-29 | 味の素株式会社 | 目的物質の製造法 |
| KR102284843B1 (ko) * | 2019-10-08 | 2021-08-02 | 씨제이제일제당 주식회사 | 5'-구아닐산이나트륨 7수화물 결정의 제조 방법 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4944350B1 (hu) * | 1967-06-16 | 1974-11-27 | ||
| NL7209936A (hu) | 1972-07-19 | 1974-01-22 | ||
| JPS5682098A (en) | 1979-12-06 | 1981-07-04 | Ajinomoto Co Inc | Production of purine nucleoside-5'-monophosphate |
| JPH0669386B2 (ja) | 1987-03-18 | 1994-09-07 | 協和醗酵工業株式会社 | ５′−イノシン酸の製造法 |
| DE69024639T2 (de) * | 1989-12-05 | 1996-06-05 | Kyowa Hakko Kogyo Kk | Inosin-guanosin-kinase |
| US5756315A (en) * | 1989-12-05 | 1998-05-26 | Kyowa Hakko Kogyo Co., Ltd. | Inosine-guanosine kinase |
-
1996
- 1996-03-22 JP JP52915796A patent/JP3948027B2/ja not_active Expired - Fee Related
- 1996-03-22 PL PL96322580A patent/PL184520B1/pl not_active IP Right Cessation
- 1996-03-22 BR BR9607745A patent/BR9607745A/pt not_active IP Right Cessation
- 1996-03-22 EP EP96906930A patent/EP0816491B1/en not_active Expired - Lifetime
- 1996-03-22 US US08/913,816 patent/US6673576B1/en not_active Expired - Fee Related
- 1996-03-22 DE DE69637616T patent/DE69637616D1/de not_active Expired - Lifetime
- 1996-03-22 HU HU9801687A patent/HUP9801687A3/hu not_active Application Discontinuation
- 1996-03-22 KR KR1019970706658A patent/KR100376635B1/ko not_active IP Right Cessation
- 1996-03-22 ES ES96906930T patent/ES2311289T3/es not_active Expired - Lifetime
- 1996-03-22 CN CN96194140A patent/CN1130457C/zh not_active Expired - Fee Related
- 1996-03-22 CA CA002216172A patent/CA2216172A1/en not_active Abandoned
- 1996-03-22 WO PCT/JP1996/000761 patent/WO1996030501A1/ja active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ES2311289T3 (es) | 2009-02-01 |
| KR100376635B1 (ko) | 2003-06-12 |
| EP0816491A1 (en) | 1998-01-07 |
| BR9607745A (pt) | 1998-06-23 |
| CN1130457C (zh) | 2003-12-10 |
| DE69637616D1 (de) | 2008-09-11 |
| JP3948027B2 (ja) | 2007-07-25 |
| CA2216172A1 (en) | 1996-10-03 |
| WO1996030501A1 (fr) | 1996-10-03 |
| HUP9801687A3 (en) | 2000-06-28 |
| EP0816491B1 (en) | 2008-07-30 |
| PL322580A1 (en) | 1998-02-02 |
| US6673576B1 (en) | 2004-01-06 |
| EP0816491A4 (en) | 2000-11-22 |
| CN1185174A (zh) | 1998-06-17 |
| KR19980703254A (ko) | 1998-10-15 |
| PL184520B1 (pl) | 2002-11-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUP9801687A2 (hu) | Eljárás nukleinsavak előállítására | |
| HU912253D0 (en) | Process for the production of purinyl-phosphonic acid derivatives | |
| WO1995004162A3 (en) | Dna sequencing enzymes | |
| AU658634B2 (en) | Synthetic catalytic oligonucleotide structures containing modified nucleotides | |
| AU2489197A (en) | Carbocyclic intermediates and process of manufacture thereof | |
| CA2123354A1 (en) | Thermostable nucleic acid polymerase | |
| ES2002653A6 (es) | Procedimiento para la preparacion de 7-desaza-2'-desoxiguanosin-nucleotidos. | |
| HU9501963D0 (en) | 7-deazapurine modified oligonucleotides | |
| ES2150795T3 (es) | Fitasa de peniophora. | |
| ATE466864T1 (de) | Nichtaggregierende, nichtausschaltende oligomere, nukleotid-analoga enthaltend; verfahren zu deren herstellung und verwendung | |
| CA2268703A1 (en) | Enantiomerically pure .beta.-d-dioxolane nucleosides with selective anti-hepatitis b virus activity | |
| DE69308908D1 (de) | Verfahren zur Herstellung von Cytidin-Diphosphat-Cholin | |
| Sulston et al. | Non-enzymic oligonucleotide synthesis on a polycytidylate template | |
| HUP9900808A2 (hu) | Eljárás nukleozid-5'-foszfát-észterek előállítására | |
| Krupp et al. | Sequence changes in both flanking sequences of a pre-tRNA influence the cleavage specificity of RNase P | |
| Wang et al. | Translation of a specific mRNA from Escherichiacoli in a eukaryotic cell-free system | |
| HK1034512A1 (en) | Process for the production of purine derivatives and intermediates therefor | |
| ATE203271T1 (de) | Für die protein-kinase a-spezifische modifizierte oligonukleotide und verfahren zur deren verwendung | |
| CA2046865A1 (en) | Inosine-guanosine kinase | |
| WO1999066051A3 (en) | Nek-related and bub1-related protein kinases | |
| DK0862628T3 (da) | Receptor og nukleinsyremolekyle, der koder for receptoren | |
| EP0335770A3 (en) | Novel fluorophosphonate nucleotide derivatives | |
| CA2352073A1 (en) | F0f1-atpase and dna encoding the same | |
| JPS6422853A (en) | Nucleoside analog | |
| TH26076A (th) | กระบวนการสำหรับการผลิตกรดนิวคลีอิก |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC4A | Lapse of provisional application due to refusal |