HUP9801158A2 - Imidazolszármazékok és ilyen vegyületeket tartalmazó gyógyászati készítmények - Google Patents

Imidazolszármazékok és ilyen vegyületeket tartalmazó gyógyászati készítmények

Info

Publication number
HUP9801158A2
HUP9801158A2 HU9801158A HUP9801158A HUP9801158A2 HU P9801158 A2 HUP9801158 A2 HU P9801158A2 HU 9801158 A HU9801158 A HU 9801158A HU P9801158 A HUP9801158 A HU P9801158A HU P9801158 A2 HUP9801158 A2 HU P9801158A2
Authority
HU
Hungary
Prior art keywords
group
general formula
imidazole derivatives
short
powder
Prior art date
Application number
HU9801158A
Other languages
English (en)
Inventor
Yukitaka Ideyama
Tsukasa Ishihara
Isao Kinoyama
Masafumi Kudoh
Minoru Okada
Syuichi Sakuda
Toru Yoden
Original Assignee
Yamanouchi Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co., Ltd. filed Critical Yamanouchi Pharmaceutical Co., Ltd.
Publication of HUP9801158A2 publication Critical patent/HUP9801158A2/hu
Publication of HUP9801158A3 publication Critical patent/HUP9801158A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

A találmány új (I) általánős képletű imidazőlszármazékőkra, valamintezek sóira, hidrátjaira és szőlvátjaira vőnatkőzik - az (I) általánősképletben A jelentése hidrőxilcsőpőrttal, arilcsőpőrttal, rövid szénláncúalkilidéncsőpőrttal vagy őxőcsőpőrttal (=O) adőtt esetbenszűbszitűált, rövid szénláncú alkiléncsőpőrt; X jelentése metiléncsőpőrt vagy -NR2- általánős képletű csőpőrt; R1 jelentése hidrőgénatőm, rövid szénláncú alkilcsőpőrt vagyaralkilcsőpőrt; és R2 jelentése hidrőgénatőm vagy rövid szénláncú alkilcsőpőrt. Atalálmány szerinti vegyületek a szterőid 17-20 liázt inhibitálóhatásúak és így őlyan megbetegedések kezelésére vagy megelőzésérealkalmasak, mint példáűl prősztatarák, rősszindűlatú prősztata-hiperplázia, női hermafrőditizműs, rendellenes szőrösség, mellrák,méhizőmdaganat, méhnyálkahártya-gyűlladás és emlőbetegség. ŕ
HU9801158A 1995-03-01 1996-03-01 Imidazole derivatives and medicinal composition thereof HUP9801158A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4206795 1995-03-01

Publications (2)

Publication Number Publication Date
HUP9801158A2 true HUP9801158A2 (hu) 1999-08-30
HUP9801158A3 HUP9801158A3 (en) 1999-11-29

Family

ID=12625750

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9801158A HUP9801158A3 (en) 1995-03-01 1996-03-01 Imidazole derivatives and medicinal composition thereof

Country Status (10)

Country Link
EP (1) EP0820989A4 (hu)
KR (1) KR19980702319A (hu)
CN (1) CN1177350A (hu)
AU (1) AU702406B2 (hu)
CA (1) CA2213246A1 (hu)
HU (1) HUP9801158A3 (hu)
NO (1) NO973980L (hu)
NZ (1) NZ302392A (hu)
PL (1) PL322028A1 (hu)
WO (1) WO1996026927A1 (hu)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1073640B1 (en) * 1998-04-23 2005-04-13 Takeda Pharmaceutical Company Limited Naphthalene derivatives, their production and use
JP4546589B2 (ja) * 1998-04-23 2010-09-15 武田薬品工業株式会社 ナフタレン誘導体
PE20010781A1 (es) 1999-10-22 2001-08-08 Takeda Chemical Industries Ltd Compuestos 1-(1h-imidazol-4-il)-1-(naftil-2-sustituido)etanol, su produccion y utilizacion
ATE321552T1 (de) 1999-10-22 2006-04-15 Takeda Pharmaceutical 1-substituierte-phenyl-1-(1h-imidazol-4- yl)alkohole, verfahren zu deren herstellung sowie deren verwendung
JP4520012B2 (ja) * 1999-10-22 2010-08-04 武田薬品工業株式会社 １−置換−１−（１ｈ−イミダゾール−４−イル）メタノール類
EP1348706B1 (en) * 2000-12-08 2009-08-19 Takeda Pharmaceutical Company Limited Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparing the same and use thereof
US7183305B2 (en) 2003-11-11 2007-02-27 Allergan, Inc. Process for the synthesis of imidazoles
US7880017B2 (en) 2003-11-11 2011-02-01 Allergan, Inc. Process for the synthesis of imidazoles
US8080566B1 (en) 2008-06-11 2011-12-20 Kalypsys, Inc Carbazole inhibitors of histamine receptors for the treatment of disease
JP6275378B2 (ja) * 2012-12-26 2018-02-07 エヌ・イーケムキャット株式会社 カルバゾール類の製造方法およびこの方法により製造されたカルバゾール類。
US20170158636A1 (en) * 2014-07-16 2017-06-08 Novogen Ltd. Functionalised and substituted carbazoles as anti-cancer agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5753466A (en) * 1980-09-17 1982-03-30 Dai Ichi Seiyaku Co Ltd 2-substituted imidazole compound
US4533670A (en) * 1983-09-21 1985-08-06 Eli Lilly And Company Anti-convulsant fluorenylalkylimidazole derivatives, compositions, and method of use
NZ221729A (en) * 1986-09-15 1989-07-27 Janssen Pharmaceutica Nv Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions
GB9310635D0 (en) * 1993-05-21 1993-07-07 Glaxo Group Ltd Chemical compounds
AU7275894A (en) * 1993-08-04 1995-02-28 Yamanouchi Pharmaceutical Co., Ltd. Imidazolylalkylamine derivative and pharmaceutical composition thereof

Also Published As

Publication number Publication date
EP0820989A1 (en) 1998-01-28
WO1996026927A1 (fr) 1996-09-06
NO973980L (no) 1997-10-31
NZ302392A (en) 1998-08-26
AU4843996A (en) 1996-09-18
NO973980D0 (no) 1997-08-29
KR19980702319A (ko) 1998-07-15
HUP9801158A3 (en) 1999-11-29
CN1177350A (zh) 1998-03-25
PL322028A1 (en) 1998-01-05
EP0820989A4 (en) 1998-05-06
CA2213246A1 (en) 1996-09-06
AU702406B2 (en) 1999-02-18
MX9706585A (es) 1997-11-29

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