ES8705393A1 - Un procedimiento para preparar un derivado de pirazol (como divisional de la solicitud de patente de invencion n 543.046, presentada el 10.5.85) - Google Patents

Un procedimiento para preparar un derivado de pirazol (como divisional de la solicitud de patente de invencion n 543.046, presentada el 10.5.85)

Info

Publication number
ES8705393A1
ES8705393A1 ES551362A ES551362A ES8705393A1 ES 8705393 A1 ES8705393 A1 ES 8705393A1 ES 551362 A ES551362 A ES 551362A ES 551362 A ES551362 A ES 551362A ES 8705393 A1 ES8705393 A1 ES 8705393A1
Authority
ES
Spain
Prior art keywords
alkyl
substituted
hydrogen
nr7r8
inflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES551362A
Other languages
English (en)
Other versions
ES551362A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Ltd
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848412181A external-priority patent/GB8412181D0/en
Priority claimed from GB848429128A external-priority patent/GB8429128D0/en
Application filed by Fisons Ltd filed Critical Fisons Ltd
Publication of ES551362A0 publication Critical patent/ES551362A0/es
Publication of ES8705393A1 publication Critical patent/ES8705393A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heat Treatment Of Sheet Steel (AREA)
  • Jib Cranes (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UN DERIVADO DE PIRAZOL. CONSISTE EN OXIDAR SELECTIVAMENTE UN COMPUESTO DE FORMULA (II) PARA OBTENER DERIVADOS DE PIRAZOL DE FORMULA (I) DONDE R2 ES H, ALQUILO O AR2, Y R3 ES H, ALQUILO O ALQUILO SUSTITUIDO POR AR3 Y OTROS; R4 Y R5 PUEDEN SER IGUALES O DIFERENTES Y REPRESENTAN CADA UNO H, HALOGENO, AR, ALQUILO O ALQUILO SUSTITUIDO POR AR; Y AR1, AR2 Y AR QUE PUEDEN SER IGUALES O DIFERENTES REPRESENTAN ARILO O ARILO SUSTITUIDO POR UNO O MAS DE HALOGENO Y OTROS. TIENEN UTILIDAD EN LA PREPARACION DE COMPUESTOS FARMACEUTICOS.
ES551362A 1984-05-12 1986-01-29 Un procedimiento para preparar un derivado de pirazol (como divisional de la solicitud de patente de invencion n 543.046, presentada el 10.5.85) Expired ES8705393A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB848412181A GB8412181D0 (en) 1984-05-12 1984-05-12 Heterocyclic compounds
GB848429128A GB8429128D0 (en) 1984-11-17 1984-11-17 Heterocyclic compounds
EP85303081A EP0178035B1 (en) 1984-05-12 1985-05-01 Anti-inflammatory 1,n-diarylpyrazol-3-amines, compositions containing them and processes for their preparation

Publications (2)

Publication Number Publication Date
ES551362A0 ES551362A0 (es) 1987-05-01
ES8705393A1 true ES8705393A1 (es) 1987-05-01

Family

ID=26287734

Family Applications (2)

Application Number Title Priority Date Filing Date
ES543046A Expired ES8609267A1 (es) 1984-05-12 1985-05-10 Un procedimiento para preparar un derivado de pirazol
ES551362A Expired ES8705393A1 (es) 1984-05-12 1986-01-29 Un procedimiento para preparar un derivado de pirazol (como divisional de la solicitud de patente de invencion n 543.046, presentada el 10.5.85)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES543046A Expired ES8609267A1 (es) 1984-05-12 1985-05-10 Un procedimiento para preparar un derivado de pirazol

Country Status (15)

Country Link
US (1) US4810719A (es)
EP (1) EP0178035B1 (es)
JP (1) JPH0625134B2 (es)
AT (1) ATE49198T1 (es)
AU (1) AU586166B2 (es)
CA (1) CA1246567A (es)
DE (1) DE3575130D1 (es)
DK (1) DK204085A (es)
ES (2) ES8609267A1 (es)
FI (1) FI851836L (es)
GR (1) GR851132B (es)
IL (1) IL75146A (es)
NO (1) NO169283C (es)
NZ (1) NZ212025A (es)
PT (1) PT80435B (es)

Families Citing this family (44)

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US4824859A (en) * 1983-05-21 1989-04-25 Fisons Plc. Pyrazoline compounds compositions and use
IL73418A (en) * 1983-11-07 1988-02-29 Lilly Co Eli 5-cyano-1h-pyrazole-4-(thio)carboxamide derivatives,their preparation and herbicidal compositions containing them
DE3773746D1 (en) * 1986-05-07 1991-11-21 Fisons Plc Pyrazole.
EP0254259A3 (en) * 1986-07-21 1989-11-23 Otsuka Pharmaceutical Factory, Inc. P-aminophenol derivatives
US4970210A (en) * 1987-07-17 1990-11-13 Abbott Laboratories Triazinone lipoxygenase compounds
GR900100380A (el) * 1989-05-20 1991-10-10 Fisons Plc Μέ?οδος παρασκευής αντι-φλεγμονωδών παραγώγων αμινοφενόλης.
PH27357A (en) * 1989-09-22 1993-06-21 Fujisawa Pharmaceutical Co Pyrazole derivatives and pharmaceutical compositions comprising the same
US5550147A (en) * 1992-02-05 1996-08-27 Fujisawa Pharmaceutical Co., Ltd. Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
AU4527996A (en) * 1994-12-13 1996-07-03 Euro-Celtique S.A. Trisubstituted thioxanthines
WO1996018399A1 (en) * 1994-12-13 1996-06-20 Euro-Celtique, S.A. Aryl thioxanthines
US6025361A (en) * 1994-12-13 2000-02-15 Euro-Celtique, S.A. Trisubstituted thioxanthines
EP0833622B8 (en) * 1995-06-12 2005-10-12 G.D. Searle & Co. Compositions comprising a cyclooxygenase-2 inhibitor and a 5-lipoxygenase inhibitor
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
WO2000025780A1 (en) * 1998-10-29 2000-05-11 Bristol-Myers Squibb Company Compounds derived from an amine nucleus that are inhibitors of impdh enzyme
WO2001057034A1 (en) 2000-02-07 2001-08-09 Bristol-Myers Squibb Co. 3-aminopyrazole inhibitors of cyclin dependent kinases
AU3217501A (en) * 2000-03-03 2001-09-12 Pfizer Prod Inc Pyrazole ether derivatives as anti-inflammatory/analgesic agents
JP4759207B2 (ja) * 2000-05-15 2011-08-31 あすか製薬株式会社 １−（ベンゾチアゾール−２−イル）ピラゾール誘導体およびそれを含有するｃｏｘ−２阻害剤
GB0016787D0 (en) 2000-07-07 2000-08-30 Pfizer Ltd Compounds useful in therapy
WO2003037352A1 (en) * 2001-11-02 2003-05-08 Pfizer Products Inc. 1-phenyl-5-n-heterocyclyl-pyrazoles as cyclooxygenase inhibitors for the treatment of inflammation associated disorders
FR2866887A1 (fr) * 2004-02-27 2005-09-02 Oreal Para-phenylenediamine secondaire n-heteroaryle, compositon tinctoriale comprenant une telle para-phenylenediamine, procede mettant en oeuvre cette composition et utilisation
US7329288B2 (en) 2004-02-27 2008-02-12 L'oreal S.A. N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof
MX2009003456A (es) * 2006-10-02 2009-04-14 Irm Llc Compuestos y composiciones como inhibidores de proteina cinasa.
US8420642B2 (en) * 2007-10-09 2013-04-16 Merck Patent Gmbh Pyridine derivatives useful as glucokinase activators
EP2358396A2 (en) * 2008-10-15 2011-08-24 Nitto Denko Corporation Method of preparing polyglutamate conjugates
US10695519B2 (en) 2009-04-02 2020-06-30 Breathe Technologies, Inc. Methods, systems and devices for non-invasive open ventilation with gas delivery nozzles within nasal pillows
CN102666566A (zh) * 2009-12-16 2012-09-12 日东电工株式会社 聚谷氨酸的受控合成
CN103402522A (zh) 2011-03-01 2013-11-20 恩法玛康有限责任公司 N-(4-甲氧基苯基)-1-苯基-1h-吡唑-3-胺及相关化合物的用途
EP3057431A4 (en) 2013-10-17 2017-04-05 Dow AgroSciences LLC Processes for the preparation of pesticidal compounds
CN105636444B (zh) 2013-10-17 2018-04-27 美国陶氏益农公司 制备杀虫化合物的方法
CA2925953C (en) 2013-10-17 2021-11-02 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds
MX2016004942A (es) 2013-10-17 2016-06-28 Dow Agrosciences Llc Procesos para la preparacion de compuestos plaguicidas.
KR20160074540A (ko) 2013-10-17 2016-06-28 다우 아그로사이언시즈 엘엘씨 살충성 화합물의 제조 방법
KR20160074542A (ko) 2013-10-17 2016-06-28 다우 아그로사이언시즈 엘엘씨 살충성 화합물의 제조 방법
WO2015103060A1 (en) 2014-01-06 2015-07-09 Algomedix, Inc. Trpa1 modulators
CA2954631A1 (en) * 2014-07-31 2016-02-04 Dow Agrosciences Llc Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
EP3174856A4 (en) 2014-07-31 2018-01-10 Dow AgroSciences LLC Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
WO2016028328A1 (en) 2014-08-19 2016-02-25 Dow Agrosciences Llc Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
KR20170058388A (ko) 2014-09-12 2017-05-26 다우 아그로사이언시즈 엘엘씨 3-(3-클로로-1h-피라졸-1-일)피리딘의 제조 방법
CN110139853B (zh) 2016-12-29 2023-06-16 美国陶氏益农公司 用于制备杀有害生物化合物的方法
WO2018125817A1 (en) 2016-12-29 2018-07-05 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds

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US3398158A (en) * 1964-02-19 1968-08-20 Warner Lambert Pharmaceutical 1-phenyl-4-alkylamino-pyrazoles
IT1061812B (it) * 1976-06-25 1983-04-30 Montedison Spa Processo per la preparazione di i fenil 3 ammino pirazoli
JPS6039269B2 (ja) * 1977-05-24 1985-09-05 三共株式会社 アシルケテン−ｓ・ｎ−アセタ−ル化合物、およびその製法
DE2747531A1 (de) * 1977-10-22 1979-04-26 Basf Ag Substituierte 3-aminopyrazole
DK302880A (da) * 1979-07-13 1981-01-14 Wellcome D Fremgangsmaade til fremstilling af et farmaceutisk praeparat indeholdende en 3-amino1-aryl-2-pyrazolin
DD149231A1 (de) * 1980-02-20 1981-07-01 Manfred Schulz Stabilisatoren fuer hochpolymere,niedermolekulare organische verbindungen und oele
DD151366A1 (de) * 1980-06-06 1981-10-14 Regina Werndl Diazotypiematerial mit verbesserter lichtstabilitaet der bildfarbstoffe
DE3035395A1 (de) * 1980-09-19 1982-05-06 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von pyrazol
FR2496100B1 (fr) * 1980-12-16 1985-06-14 Wellcome Found Derives de la pyrazoline, leur preparation et medicaments contenant ces substances
ZA818703B (en) * 1980-12-16 1983-07-27 Wellcome Found Heterocyclic compounds
EP0070376A1 (en) * 1981-07-13 1983-01-26 American Cyanamid Company Heterocyclic substituted-amino-pyrazolines
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GB8303782D0 (en) * 1983-02-11 1983-03-16 Wellcome Found Heterocyclic compounds

Also Published As

Publication number Publication date
JPH0625134B2 (ja) 1994-04-06
NO851876L (no) 1985-11-13
DE3575130D1 (de) 1990-02-08
PT80435A (en) 1985-06-01
ES543046A0 (es) 1986-07-16
NO169283C (no) 1992-06-10
AU4227585A (en) 1985-11-14
ATE49198T1 (de) 1990-01-15
IL75146A0 (en) 1985-09-29
GR851132B (es) 1985-11-25
ES551362A0 (es) 1987-05-01
AU586166B2 (en) 1989-07-06
IL75146A (en) 1989-07-31
PT80435B (en) 1987-04-13
JPS60246371A (ja) 1985-12-06
EP0178035B1 (en) 1990-01-03
EP0178035A1 (en) 1986-04-16
NZ212025A (en) 1989-03-29
ES8609267A1 (es) 1986-07-16
FI851836A0 (fi) 1985-05-09
US4810719A (en) 1989-03-07
CA1246567A (en) 1988-12-13
DK204085A (da) 1985-11-13
FI851836L (fi) 1985-11-13
DK204085D0 (da) 1985-05-08
NO169283B (no) 1992-02-24

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