HUP9802629A2 - 1,3-Bisz(1,2,4-triazolil)-2-propanol-származékok felhasználása rákos megbetegedések kezelésére szolgáló gyógyszerkészítmények előállítására - Google Patents

1,3-Bisz(1,2,4-triazolil)-2-propanol-származékok felhasználása rákos megbetegedések kezelésére szolgáló gyógyszerkészítmények előállítására

Info

Publication number
HUP9802629A2
HUP9802629A2 HU9802629A HUP9802629A HUP9802629A2 HU P9802629 A2 HUP9802629 A2 HU P9802629A2 HU 9802629 A HU9802629 A HU 9802629A HU P9802629 A HUP9802629 A HU P9802629A HU P9802629 A2 HUP9802629 A2 HU P9802629A2
Authority
HU
Hungary
Prior art keywords
triazolyl
bis
derivatives
propan
manufacture
Prior art date
Application number
HU9802629A
Other languages
English (en)
Inventor
James Berger Camden
Original Assignee
The Procter & Gamble Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Procter & Gamble Company filed Critical The Procter & Gamble Company
Publication of HUP9802629A2 publication Critical patent/HUP9802629A2/hu
Publication of HUP9802629A3 publication Critical patent/HUP9802629A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/402—1-aryl substituted, e.g. piretanide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A találmány tárgyát (I) általánős képletű 1,3-bisz-(triazőlil)-2-prőpanől származékők -, ahől R1 adőtt esetben szűbsztitűált alkil-, ciklőalkil-, aril-, halőgén-aril-vagy aril-alkil-csőpőrt - alkalmazása képezi rákős megbetegedések kezelésére szőglálógyógyszerkészítmény előállítására.A készítmény vírűsők ellen ishatásősan alkalmazhatók. ŕ
HU9802629A 1995-06-07 1996-05-22 Use of 1,3-bis(1,2,4-triazolyl)propan-2-ol derivatives for the manufacture of pharmaceutical compositions treating cancers HUP9802629A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/473,818 US5665751A (en) 1995-06-07 1995-06-07 Pharmaceutical composition for inhibiting the growth of cancers

Publications (2)

Publication Number Publication Date
HUP9802629A2 true HUP9802629A2 (hu) 1999-04-28
HUP9802629A3 HUP9802629A3 (en) 2000-01-28

Family

ID=23881116

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9802629A HUP9802629A3 (en) 1995-06-07 1996-05-22 Use of 1,3-bis(1,2,4-triazolyl)propan-2-ol derivatives for the manufacture of pharmaceutical compositions treating cancers

Country Status (20)

Country Link
US (3) US5665751A (hu)
EP (1) EP0831815A1 (hu)
JP (1) JPH11506733A (hu)
KR (1) KR19990022618A (hu)
CN (1) CN1259867A (hu)
AR (1) AR003430A1 (hu)
AU (1) AU717201B2 (hu)
BR (1) BR9609093A (hu)
CA (1) CA2223803A1 (hu)
CZ (1) CZ391897A3 (hu)
HU (1) HUP9802629A3 (hu)
IL (1) IL118426A (hu)
NO (1) NO975661L (hu)
NZ (1) NZ308393A (hu)
PL (1) PL324078A1 (hu)
SK (1) SK168797A3 (hu)
TR (2) TR199701535T1 (hu)
TW (1) TW466113B (hu)
WO (1) WO1996040120A1 (hu)
ZA (1) ZA964377B (hu)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ283135A (en) * 1994-03-21 2004-12-24 Thomsen John Brown Gel formulation for treatment of skin diseases and disinfection/disinfestation of the skin
US6262093B1 (en) 1995-04-12 2001-07-17 The Proctor & Gamble Company Methods of treating cancer with benzimidazoles
US6479526B1 (en) 1995-04-12 2002-11-12 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of viruses and cancers
US6177460B1 (en) 1995-04-12 2001-01-23 The Procter & Gamble Company Method of treatment for cancer or viral infections
US6265427B1 (en) 1995-06-07 2001-07-24 The Proctor & Gamble Company Pharmaceutical composition for the method of treating leukemia
US5770616A (en) 1995-06-07 1998-06-23 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers
US6686391B2 (en) 1995-08-04 2004-02-03 University Of Arizona Foundation N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions
PL324904A1 (en) * 1995-08-04 1998-06-22 Procter & Gamble Application of fluconazole in carcinoma development inhibition
US5900429A (en) 1997-01-28 1999-05-04 The Procter & Gamble Company Method for inhibiting the growth of cancers
US6506783B1 (en) 1997-05-16 2003-01-14 The Procter & Gamble Company Cancer treatments and pharmaceutical compositions therefor
US6245789B1 (en) 1998-05-19 2001-06-12 The Procter & Gamble Company HIV and viral treatment
US6136835A (en) * 1999-05-17 2000-10-24 The Procter & Gamble Company Methods of treatment for viral infections
US6423734B1 (en) 1999-08-13 2002-07-23 The Procter & Gamble Company Method of preventing cancer
US6407105B1 (en) 2000-09-26 2002-06-18 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US6608096B1 (en) 2000-09-26 2003-08-19 University Of Arizona Foundation Compounds and methods for use thereof in the treatment of cancer or viral infections
US6462062B1 (en) * 2000-09-26 2002-10-08 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US6380232B1 (en) 2000-09-26 2002-04-30 The Procter & Gamble Company Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof
US6515074B2 (en) * 2001-01-22 2003-02-04 Delphi Technologies, Inc. Thermoplastic polymer alloy compositions and process for manufacture thereof
CN100334084C (zh) * 2005-04-26 2007-08-29 武汉大学 联三唑化合物及其制备方法和用途
CN100451007C (zh) * 2006-10-12 2009-01-14 杭州宇龙化工有限公司 含芳醚双三氮唑类化合物及其用途
US8536113B2 (en) 2006-12-21 2013-09-17 Janssen Biotech, Inc. EGFR binding peptides and uses thereof
US8278415B2 (en) 2006-12-21 2012-10-02 Centocor, Inc. Dimeric high affinity EGFR constructs and uses thereof
US8834920B2 (en) 2006-12-21 2014-09-16 Alza Corporation Liposome composition for targeting egfr receptor
KR100980328B1 (ko) * 2007-12-14 2010-09-06 한국생명공학연구원 단백질 포스파타제의 활성을 억제하는트리아졸릴-티오-에타논 유도체 또는 이의 약학적으로 허용가능한 염을 유효성분으로 함유하는 암 예방 및 치료용조성물
CN102321036A (zh) * 2011-07-13 2012-01-18 王健祥 一种氟康唑可溶性盐的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4079062A (en) * 1974-11-18 1978-03-14 Janssen Pharmaceutica N.V. Triazole derivatives
US4160838A (en) * 1977-06-02 1979-07-10 Janssen Pharmaceutica N.V. Antimicrobial and plant-growth-regulating triazole derivatives
GB2078719B (en) * 1980-06-02 1984-04-26 Ici Ltd Heterocyclic compounds
DE3262386D1 (en) * 1981-06-06 1985-03-28 Pfizer Ltd Antifungal agents, processes for their preparation, and pharmaceutical compositions containing them
DE3837463A1 (de) * 1988-11-04 1990-05-10 Bayer Ag Substituierte bisazole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
BE1004029A6 (nl) * 1990-11-22 1992-09-08 Mol Omer De Farmaceutische samenstelling en farmaceutische set voor het behandelen van kanker.
US5360612A (en) * 1992-10-13 1994-11-01 Pfizer Inc. Pharmaceutical compositions containing triazole derivatives for rectal administration

Also Published As

Publication number Publication date
SK168797A3 (en) 1998-12-02
EP0831815A1 (en) 1998-04-01
NZ308393A (en) 2001-04-27
BR9609093A (pt) 1999-06-29
KR19990022618A (ko) 1999-03-25
CZ391897A3 (cs) 1998-05-13
ZA964377B (en) 1997-02-17
TR200102287T2 (tr) 2002-06-21
TW466113B (en) 2001-12-01
NO975661D0 (no) 1997-12-05
AR003430A1 (es) 1998-08-05
HUP9802629A3 (en) 2000-01-28
USRE37003E (en) 2000-12-26
PL324078A1 (en) 1998-05-11
WO1996040120A1 (en) 1996-12-19
AU717201B2 (en) 2000-03-23
IL118426A (en) 2001-03-19
US5840742A (en) 1998-11-24
TR199701535T1 (xx) 1998-03-21
US5665751A (en) 1997-09-09
AU5802196A (en) 1996-12-30
JPH11506733A (ja) 1999-06-15
IL118426A0 (en) 1996-09-12
CN1259867A (zh) 2000-07-12
NO975661L (no) 1998-02-09
CA2223803A1 (en) 1996-12-19

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