ATE272629T1 - Benzothiophene - Google Patents
BenzothiopheneInfo
- Publication number
- ATE272629T1 ATE272629T1 AT98307627T AT98307627T ATE272629T1 AT E272629 T1 ATE272629 T1 AT E272629T1 AT 98307627 T AT98307627 T AT 98307627T AT 98307627 T AT98307627 T AT 98307627T AT E272629 T1 ATE272629 T1 AT E272629T1
- Authority
- AT
- Austria
- Prior art keywords
- formula
- compounds
- benzothiophene
- cervix
- uterus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5962097P | 1997-09-23 | 1997-09-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE272629T1 true ATE272629T1 (de) | 2004-08-15 |
Family
ID=22024136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98307627T ATE272629T1 (de) | 1997-09-23 | 1998-09-21 | Benzothiophene |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0905132B1 (de) |
| JP (1) | JP2001517664A (de) |
| AT (1) | ATE272629T1 (de) |
| AU (1) | AU9493698A (de) |
| CA (1) | CA2304138A1 (de) |
| DE (1) | DE69825381T2 (de) |
| ES (1) | ES2226072T3 (de) |
| WO (1) | WO1999015521A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602004016331D1 (de) | 2003-06-10 | 2008-10-16 | Lilly Co Eli | Pentafluoroalkylsulfin-naphthaline und und darauf bezogene modulatoren des östrogenrezeptors |
| CA2928173C (en) | 2012-10-24 | 2021-10-19 | The Board Of Trustees Of The University Of Illinois | Compositions comprising benzothiophene derivatives and use thereof for treatment of estrogen-related medical disorders |
| US20150284357A1 (en) | 2012-10-24 | 2015-10-08 | Gregory R. Thatcher | Compositions and methods for treating estrogen-related medical disorders |
| GB201311888D0 (en) * | 2013-07-03 | 2013-08-14 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
| EP3512842B1 (de) | 2016-09-15 | 2024-01-17 | Arvinas, Inc. | Indolderivate als abbauer des östrogenrezeptors |
| KR102173464B1 (ko) | 2016-12-01 | 2020-11-04 | 아비나스 오퍼레이션스, 인코포레이티드 | 에스트로겐 수용체 분해제로서의 테트라히드로나프탈렌 및 테트라히드로이소퀴놀린 유도체 |
| EP3573977A4 (de) | 2017-01-26 | 2020-12-23 | Arvinas Operations, Inc. | Modulatoren der östrogenrezeptorproteolyse und zugehörige verfahren zur verwendung |
| JP2021512153A (ja) | 2018-01-26 | 2021-05-13 | イエール ユニバーシティ | タンパク質分解のイミド系モジュレーターおよび使用方法 |
| KR20220119094A (ko) | 2019-12-19 | 2022-08-26 | 아비나스 오퍼레이션스, 인코포레이티드 | 안드로겐 수용체의 표적화된 분해를 위한 화합물 및 방법 |
| CN116813603A (zh) * | 2023-06-02 | 2023-09-29 | 成都市第三人民医院 | 一种选择性雌激素受体α降解化合物及其制备方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5589482A (en) * | 1994-12-14 | 1996-12-31 | Pfizer Inc. | Benzo-thiophene estrogen agonists to treat prostatic hyperplasia |
| US6444688B1 (en) * | 1995-06-07 | 2002-09-03 | Eli Lilly And Company | Compounds and compositions with nitrogen-containing non-basic side chains |
| ES2124064T3 (es) * | 1995-06-07 | 1999-01-16 | Lilly Co Eli | Compuestos y composiciones con cadenas laterales nitrogenadas no basicas. |
| US5728724A (en) * | 1995-08-17 | 1998-03-17 | Eli Lilly And Company | Benzothiophene compounds |
| EA000767B1 (ru) * | 1996-02-22 | 2000-04-24 | Эли Лилли Энд Компани | Бензотиофены, составы, их содержащие, и способы с их использованием |
-
1998
- 1998-09-18 JP JP2000512826A patent/JP2001517664A/ja not_active Withdrawn
- 1998-09-18 CA CA002304138A patent/CA2304138A1/en not_active Abandoned
- 1998-09-18 WO PCT/US1998/019557 patent/WO1999015521A1/en active Search and Examination
- 1998-09-18 AU AU94936/98A patent/AU9493698A/en not_active Abandoned
- 1998-09-21 EP EP98307627A patent/EP0905132B1/de not_active Expired - Lifetime
- 1998-09-21 DE DE69825381T patent/DE69825381T2/de not_active Expired - Fee Related
- 1998-09-21 ES ES98307627T patent/ES2226072T3/es not_active Expired - Lifetime
- 1998-09-21 AT AT98307627T patent/ATE272629T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69825381D1 (de) | 2004-09-09 |
| EP0905132B1 (de) | 2004-08-04 |
| CA2304138A1 (en) | 1999-04-01 |
| ES2226072T3 (es) | 2005-03-16 |
| AU9493698A (en) | 1999-04-12 |
| EP0905132A1 (de) | 1999-03-31 |
| JP2001517664A (ja) | 2001-10-09 |
| WO1999015521A1 (en) | 1999-04-01 |
| DE69825381T2 (de) | 2005-07-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |