HUP0402491A2 - Eljárás 2-(szubsztituált fenil)-2-hidroxi-etil-karbamátok előállítására - Google Patents

Eljárás 2-(szubsztituált fenil)-2-hidroxi-etil-karbamátok előállítására Download PDF

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Publication number
HUP0402491A2
HUP0402491A2 HU0402491A HUP0402491A HUP0402491A2 HU P0402491 A2 HUP0402491 A2 HU P0402491A2 HU 0402491 A HU0402491 A HU 0402491A HU P0402491 A HUP0402491 A HU P0402491A HU P0402491 A2 HUP0402491 A2 HU P0402491A2
Authority
HU
Hungary
Prior art keywords
formula
compound
group
substituted
ester
Prior art date
Application number
HU0402491A
Other languages
English (en)
Hungarian (hu)
Inventor
Thomas Otten
Daniel Korey
Max Rey
Original Assignee
Ortho-Mcneil Pharmaceutical, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho-Mcneil Pharmaceutical, Inc. filed Critical Ortho-Mcneil Pharmaceutical, Inc.
Publication of HUP0402491A2 publication Critical patent/HUP0402491A2/hu

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/12Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734Ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/03Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14Unsaturated ethers
    • C07C43/178Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1786Unsaturated ethers containing hydroxy or O-metal groups containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU0402491A 2001-12-21 2002-12-19 Eljárás 2-(szubsztituált fenil)-2-hidroxi-etil-karbamátok előállítására HUP0402491A2 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01205097 2001-12-21
US41808402P 2002-10-11 2002-10-11
PCT/EP2002/014843 WO2003053916A1 (en) 2001-12-21 2002-12-19 Process for preparing 2-(substituted phenyl) - 2 - hydroxy-ethyl carbamates

Publications (1)

Publication Number Publication Date
HUP0402491A2 true HUP0402491A2 (hu) 2005-04-28

Family

ID=26077052

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0402491A HUP0402491A2 (hu) 2001-12-21 2002-12-19 Eljárás 2-(szubsztituált fenil)-2-hidroxi-etil-karbamátok előállítására

Country Status (22)

Country Link
EP (2) EP2248799B1 (enExample)
JP (1) JP4610899B2 (enExample)
KR (1) KR20090097966A (enExample)
CN (1) CN100457723C (enExample)
AR (1) AR038055A1 (enExample)
AU (3) AU2002358806B2 (enExample)
BG (1) BG108759A (enExample)
BR (1) BR0215237A (enExample)
CA (2) CA2471485C (enExample)
CZ (1) CZ2004718A3 (enExample)
EE (1) EE05381B1 (enExample)
HR (1) HRP20040557A2 (enExample)
HU (1) HUP0402491A2 (enExample)
IL (3) IL162405A0 (enExample)
MX (1) MXPA04006135A (enExample)
MY (1) MY142415A (enExample)
NO (1) NO20043105L (enExample)
NZ (1) NZ533592A (enExample)
PL (1) PL370977A1 (enExample)
SK (1) SK2572004A3 (enExample)
TW (1) TWI333944B (enExample)
WO (1) WO2003053916A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7767843B2 (en) * 2006-03-02 2010-08-03 Apotex Pharmachem Inc. Process for the preparation of phenylcarbamates
US7632963B2 (en) * 2006-10-06 2009-12-15 Janssen Pharmaceutica Nv Crystal of (S)-(+)-2-(2-chlorophenyl)-2-hydroxy-ethyl carbamate
US20090105498A1 (en) * 2007-10-18 2009-04-23 Porstmann Frank Improved process for preparing 2-(substituted phenyol)-2-hydroxy-ethyl-carbamates
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
EP2797878B1 (en) * 2011-12-27 2017-08-16 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compounds for use in preventing or treating stroke
KR102421006B1 (ko) * 2016-05-19 2022-07-14 에스케이바이오팜 주식회사 두통의 예방학적 치료를 위한 카바메이트 화합물의 용도

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5671M (enExample) * 1965-04-23 1968-01-02
US5504108A (en) * 1990-01-12 1996-04-02 The Ohio State University Research Foundation Optically pure 4-aryl-2-hydroxytetronic acids
JP3010497B2 (ja) * 1990-05-31 2000-02-21 チッソ株式会社 光学活性α―ヒドロキシエステル類の製造方法
JP3004361B2 (ja) 1994-10-19 2000-01-31 フイルメニツヒ ソシエテ アノニム アルコールの製造方法
US5698588A (en) 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
US6642395B1 (en) * 1999-11-29 2003-11-04 Mitsubishi Rayon Co., Ltd. Acetalsulfonate derivative, process for producing the same, and process for producing styrene oxide derivative

Also Published As

Publication number Publication date
SK2572004A3 (sk) 2005-02-04
KR20090097966A (ko) 2009-09-16
NO20043105L (no) 2004-07-20
PL370977A1 (en) 2005-06-13
EE200400098A (et) 2004-10-15
CA2471485A1 (en) 2003-07-03
EP1461309A1 (en) 2004-09-29
EP2248799A1 (en) 2010-11-10
BG108759A (bg) 2005-03-31
JP2005513126A (ja) 2005-05-12
TWI333944B (en) 2010-12-01
CN1620425A (zh) 2005-05-25
IL213960A0 (en) 2011-08-31
MXPA04006135A (es) 2004-11-01
EE05381B1 (et) 2011-02-15
JP4610899B2 (ja) 2011-01-12
AU2002358806B2 (en) 2009-09-10
MY142415A (en) 2010-11-30
TW200405809A (en) 2004-04-16
AU2002358806A1 (en) 2003-07-09
AU2011201613A1 (en) 2011-04-28
CN100457723C (zh) 2009-02-04
WO2003053916A1 (en) 2003-07-03
AU2009212987A1 (en) 2009-10-01
CA2681964A1 (en) 2003-07-03
HRP20040557A2 (en) 2005-04-30
EP2248799B1 (en) 2015-05-20
CA2471485C (en) 2011-05-24
IL162405A0 (en) 2005-11-20
BR0215237A (pt) 2004-11-16
IL162405A (en) 2011-08-31
NZ533592A (en) 2006-05-26
CZ2004718A3 (cs) 2004-12-15
AR038055A1 (es) 2004-12-22

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees