HUP0401340A2 - Enzimes eljárás aminosavak enantiomer rezolválására - Google Patents

Enzimes eljárás aminosavak enantiomer rezolválására

Info

Publication number
HUP0401340A2
HUP0401340A2 HU0401340A HUP0401340A HUP0401340A2 HU P0401340 A2 HUP0401340 A2 HU P0401340A2 HU 0401340 A HU0401340 A HU 0401340A HU P0401340 A HUP0401340 A HU P0401340A HU P0401340 A2 HUP0401340 A2 HU P0401340A2
Authority
HU
Hungary
Prior art keywords
amino acids
enantiomer
enzymatic method
enantiomeric resolution
amino acid
Prior art date
Application number
HU0401340A
Other languages
English (en)
Inventor
Christophe Salagnad
Marie-Odile Dury
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of HUP0401340A2 publication Critical patent/HUP0401340A2/hu
Publication of HUP0401340A3 publication Critical patent/HUP0401340A3/hu
Publication of HU228897B1 publication Critical patent/HU228897B1/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A találmány új enzimes eljárásra vonatkozik, amellyel aminosavenantiomer rezolválása lehetséges. Pontosabban az eljárás abból áll,hogy az aminosav racém elegyét glutársav-anhidriddel, majd a glutaril7-ACA aciláz enzimmel reagáltatják, így az aminosav egyikenantiomerjét kinyerik, míg a másik enantiomer a megfelelő glutaril-amid- származék formájában marad. Ó
HU0401340A 2001-09-04 2002-08-30 Enzimes eljárás aminosavak enantiomer rezolválására HU228897B1 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0111431A FR2829152B1 (fr) 2001-09-04 2001-09-04 Procede enzymatique pour la resolution enantiomerique d'acides amines
US33161301P 2001-11-20 2001-11-20
PCT/FR2002/002976 WO2003020943A2 (fr) 2001-09-04 2002-08-30 Procede enzymatique pour la resolution enantiomerique d'acides amines

Publications (3)

Publication Number Publication Date
HUP0401340A2 true HUP0401340A2 (hu) 2004-10-28
HUP0401340A3 HUP0401340A3 (en) 2006-01-30
HU228897B1 HU228897B1 (hu) 2013-06-28

Family

ID=8866950

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0401340A HU228897B1 (hu) 2001-09-04 2002-08-30 Enzimes eljárás aminosavak enantiomer rezolválására

Country Status (23)

Country Link
EP (1) EP1427840B1 (hu)
JP (1) JP4222939B2 (hu)
KR (1) KR100924241B1 (hu)
CN (1) CN1245519C (hu)
AR (1) AR036410A1 (hu)
AT (1) ATE341641T1 (hu)
BR (1) BR0212272A (hu)
CA (1) CA2459246C (hu)
CY (1) CY1105864T1 (hu)
DE (1) DE60215206T2 (hu)
DK (1) DK1427840T3 (hu)
EA (1) EA009322B1 (hu)
ES (1) ES2272779T3 (hu)
FR (1) FR2829152B1 (hu)
HU (1) HU228897B1 (hu)
MY (1) MY127965A (hu)
NZ (1) NZ530855A (hu)
PL (1) PL367737A1 (hu)
PT (1) PT1427840E (hu)
TW (1) TWI252869B (hu)
WO (1) WO2003020943A2 (hu)
YU (1) YU16904A (hu)
ZA (1) ZA200401226B (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4655539B2 (ja) 2004-08-06 2011-03-23 味の素株式会社 アシラーゼを用いたβアミノ酸の製造方法
JP5119783B2 (ja) * 2006-07-26 2013-01-16 味の素株式会社 N−アセチル−(R,S)−β−アミノ酸アシラーゼ遺伝子
DE602007005880D1 (de) * 2006-07-26 2010-05-27 Ajinomoto Kk N-Acetyl-(R,S)-B-Aminosäuren-Acylase-Gene
CN109456220B (zh) * 2018-11-16 2021-10-08 浙江工业大学 一种手性n-苯乙酰氨基酸及其衍生物的消旋方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0979303A1 (en) * 1997-05-01 2000-02-16 G.D. SEARLE & CO. Method and apparatus for preparation of chiral beta amino acids

Also Published As

Publication number Publication date
ZA200401226B (en) 2005-03-10
YU16904A (sh) 2006-08-17
ATE341641T1 (de) 2006-10-15
HUP0401340A3 (en) 2006-01-30
TWI252869B (en) 2006-04-11
KR100924241B1 (ko) 2009-10-30
BR0212272A (pt) 2004-10-19
FR2829152B1 (fr) 2004-09-10
EA009322B1 (ru) 2007-12-28
WO2003020943A3 (fr) 2004-02-12
EP1427840B1 (fr) 2006-10-04
KR20040044542A (ko) 2004-05-28
EA200400395A1 (ru) 2004-08-26
ES2272779T3 (es) 2007-05-01
DE60215206T2 (de) 2007-08-23
CA2459246A1 (en) 2003-03-13
JP4222939B2 (ja) 2009-02-12
EP1427840A2 (fr) 2004-06-16
CY1105864T1 (el) 2011-02-02
NZ530855A (en) 2005-11-25
PL367737A1 (en) 2005-03-07
WO2003020943A2 (fr) 2003-03-13
PT1427840E (pt) 2007-01-31
CA2459246C (en) 2011-08-02
AR036410A1 (es) 2004-09-08
DE60215206D1 (de) 2006-11-16
FR2829152A1 (fr) 2003-03-07
CN1551922A (zh) 2004-12-01
HU228897B1 (hu) 2013-06-28
JP2005501561A (ja) 2005-01-20
MY127965A (en) 2007-01-31
DK1427840T3 (da) 2007-02-12
CN1245519C (zh) 2006-03-15

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Legal Events

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MM4A Lapse of definitive patent protection due to non-payment of fees