HUP0303496A2 - Kristályos venlafaxin bázis és a venlafaxin hidroklorid új polimorf módosulatai, eljárások ezek előállítására - Google Patents

Kristályos venlafaxin bázis és a venlafaxin hidroklorid új polimorf módosulatai, eljárások ezek előállítására

Info

Publication number
HUP0303496A2
HUP0303496A2 HU0303496A HUP0303496A HUP0303496A2 HU P0303496 A2 HUP0303496 A2 HU P0303496A2 HU 0303496 A HU0303496 A HU 0303496A HU P0303496 A HUP0303496 A HU P0303496A HU P0303496 A2 HUP0303496 A2 HU P0303496A2
Authority
HU
Hungary
Prior art keywords
venlafaxine
preparing
processes
crystalline
base
Prior art date
Application number
HU0303496A
Other languages
English (en)
Inventor
Judith Aronhime
Ben-Zion Dolitzky
Gennady Nisnevish
Shlomit Weizel
Original Assignee
Teva Pharmaceutical Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27500045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0303496(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Pharmaceutical Industries, Ltd. filed Critical Teva Pharmaceutical Industries, Ltd.
Publication of HUP0303496A2 publication Critical patent/HUP0303496A2/hu
Publication of HUP0303496A3 publication Critical patent/HUP0303496A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A találmány tárgya eljárás nagy tisztaságú venlafaxin, venlafaxin-hidroklorid, ennek új polimorf módosulatainak és szolvátjainakelőállítására. A találmány további tárgyai ezen új vegyületek. Ó
HU0303496A 2000-10-19 2001-10-19 Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof HUP0303496A3 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US24157700P 2000-10-19 2000-10-19
US25886100P 2000-12-29 2000-12-29
US27872101P 2001-03-26 2001-03-26
US29246901P 2001-05-21 2001-05-21
PCT/US2001/051017 WO2002045658A2 (en) 2000-10-19 2001-10-19 Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof

Publications (2)

Publication Number Publication Date
HUP0303496A2 true HUP0303496A2 (hu) 2004-01-28
HUP0303496A3 HUP0303496A3 (en) 2005-08-29

Family

ID=27500045

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0303496A HUP0303496A3 (en) 2000-10-19 2001-10-19 Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof

Country Status (20)

Country Link
US (1) US20020143211A1 (hu)
EP (1) EP1334082A4 (hu)
JP (2) JP2004530638A (hu)
KR (1) KR20030059206A (hu)
CN (1) CN1620420A (hu)
AU (1) AU2002241764A1 (hu)
CA (1) CA2426158A1 (hu)
CZ (1) CZ20031298A3 (hu)
DE (1) DE01988460T1 (hu)
ES (1) ES2206082T1 (hu)
HR (1) HRP20030392A2 (hu)
HU (1) HUP0303496A3 (hu)
IL (2) IL155400A0 (hu)
IS (1) IS6789A (hu)
MX (1) MXPA03003459A (hu)
NO (1) NO20031743L (hu)
PL (1) PL365895A1 (hu)
SK (1) SK5762003A3 (hu)
WO (1) WO2002045658A2 (hu)
YU (1) YU30203A (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020183553A1 (en) * 2000-10-19 2002-12-05 Ben-Zion Dolitzky Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
AU2002212340B2 (en) 2000-10-31 2006-12-14 Sandoz Ag Crystalline forms of venlafaxine hydrochloride
HUP0104872A3 (en) * 2001-11-13 2004-04-28 Egis Gyogyszergyar Nyilvanosan New polymorphic forms of venlafaxine, process for their preparation, pharmaceutical compositions containing them and their use
UA77234C2 (en) * 2001-12-05 2006-11-15 Wyeth Corp Monohydrate of venlafaxine hydrochloride and methods for its preparation (variants)
EP1451145A1 (en) 2001-12-05 2004-09-01 Wyeth Novel crystalline polymorph of venlafaxine hydrochloride and methods for the preparation thereof
WO2003050074A1 (en) * 2001-12-13 2003-06-19 Cadila Healthcare Limited Manufacture of venlafaxine hydrochloride and crystalline polymorphs thereof
EP1487429A2 (en) * 2002-03-28 2004-12-22 Synthon B.V. Compositions of venlafaxine base
AU2003226751A1 (en) 2002-03-28 2003-10-13 Synthon B.V. Low water-soluble venlafaxine salts
EP1485344A1 (en) 2002-03-28 2004-12-15 Synthon B.V. Venlafaxine besylate
DE10359154A1 (de) * 2003-12-16 2005-07-28 Krka Tovarna Zdravil, D.D. Verfahren zur Herstellung von Venlafaxin und Venlafaxinhydrochlorid der Form I
US7468428B2 (en) 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
EP1806335A4 (en) * 2004-10-20 2008-12-03 Mitsubishi Tanabe Pharma Corp METHOD FOR PRODUCING A PHENYLETHANOLAMINE COMPOUND AND INTERMEDIATE PRODUCTS THEREFOR
KR20080056311A (ko) * 2005-10-19 2008-06-20 테바 파마슈티컬 인더스트리즈 리미티드 고순도1-[2-디메틸아미노-(4-메톡시페닐)에틸)시클로헥산올염산염의 제조 방법
WO2007049302A2 (en) * 2005-10-28 2007-05-03 Ind-Swift Laboratories Limited An improved process for the preparation of pure venlafaxine
EP2032521B1 (en) 2006-06-27 2009-10-28 Sandoz AG New method for salt preparation
WO2008038146A2 (en) * 2006-07-14 2008-04-03 Medichem, S.A. Improved processes for preparing vanlafaxine base and salts thereof
RU2576665C2 (ru) * 2010-10-01 2016-03-10 Йоуксин ЛИ Полиморфы 4-[2-диметиламино-1-(1-гидроксициклогексил)этил]фенил 4-метилбензоата гидрохлорида, способы их получения и использование
CR20200220A (es) 2013-11-15 2020-11-18 Akebia Therapeutics Inc FORMAS SÓLIDAS DE ÁCIDO {[5-(3-CLOROFENIL)-3-HIDROXIPIRIDIN-2-CARBONIL]AMINO}ACÉTICO, COMPOSICIONES, Y USOS DE LAS MISMAS (Divisional 2016-0222)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535186A (en) * 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
US4611078A (en) * 1983-10-26 1986-09-09 American Home Products Corporation Substituted phenylacetonitriles
AR255595A1 (hu) 1994-07-13 2002-05-24 Gador Sa
PE57198A1 (es) * 1996-03-25 1998-10-10 American Home Prod Formula de liberacion prolongada
US6197828B1 (en) * 1998-12-01 2001-03-06 Sepracor, Inc. Derivatives of (+)-venlafaxine and methods of preparing and using the same
US20020183553A1 (en) * 2000-10-19 2002-12-05 Ben-Zion Dolitzky Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
AU2002212340B2 (en) 2000-10-31 2006-12-14 Sandoz Ag Crystalline forms of venlafaxine hydrochloride
AU2001235970A1 (en) 2000-12-07 2002-06-18 Dr. Reddy's Research Foundation Novel crystalline polymorphic forms of venlafaxine hydrochloride and a process for their preparation

Also Published As

Publication number Publication date
ES2206082T1 (es) 2004-05-16
JP2008239629A (ja) 2008-10-09
KR20030059206A (ko) 2003-07-07
WO2002045658A2 (en) 2002-06-13
DE01988460T1 (de) 2004-04-22
IS6789A (is) 2003-04-15
AU2002241764A1 (en) 2002-06-18
WO2002045658A3 (en) 2003-01-16
CA2426158A1 (en) 2002-06-13
YU30203A (sh) 2006-08-17
EP1334082A2 (en) 2003-08-13
IL196287A0 (en) 2011-08-01
HUP0303496A3 (en) 2005-08-29
PL365895A1 (en) 2005-01-10
JP2004530638A (ja) 2004-10-07
SK5762003A3 (en) 2003-11-04
NO20031743L (no) 2003-06-18
CN1620420A (zh) 2005-05-25
US20020143211A1 (en) 2002-10-03
HRP20030392A2 (en) 2005-04-30
EP1334082A4 (en) 2006-02-01
NO20031743D0 (no) 2003-04-15
IL155400A0 (en) 2003-11-23
CZ20031298A3 (cs) 2003-10-15
MXPA03003459A (es) 2005-04-29

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Legal Events

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FD9A Lapse of provisional protection due to non-payment of fees