PT1501516E - Processo para a preparacao de cloridrato de benazepril - Google Patents

Processo para a preparacao de cloridrato de benazepril

Info

Publication number
PT1501516E
PT1501516E PT03722548T PT03722548T PT1501516E PT 1501516 E PT1501516 E PT 1501516E PT 03722548 T PT03722548 T PT 03722548T PT 03722548 T PT03722548 T PT 03722548T PT 1501516 E PT1501516 E PT 1501516E
Authority
PT
Portugal
Prior art keywords
preparation
benzepril
chloridrate
starting
disclosure
Prior art date
Application number
PT03722548T
Other languages
English (en)
Inventor
Graziano Castaldi
Razzetti Gabriele
Mantegazza Simone
Original Assignee
Dipharma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dipharma Spa filed Critical Dipharma Spa
Publication of PT1501516E publication Critical patent/PT1501516E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Cephalosporin Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT03722548T 2002-05-03 2003-04-25 Processo para a preparacao de cloridrato de benazepril PT1501516E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2002MI000934A ITMI20020934A1 (it) 2002-05-03 2002-05-03 Processo per la sintesi di benazepril cloridrato

Publications (1)

Publication Number Publication Date
PT1501516E true PT1501516E (pt) 2006-08-31

Family

ID=11449821

Family Applications (1)

Application Number Title Priority Date Filing Date
PT03722548T PT1501516E (pt) 2002-05-03 2003-04-25 Processo para a preparacao de cloridrato de benazepril

Country Status (15)

Country Link
US (1) US6979736B2 (pt)
EP (1) EP1501516B1 (pt)
JP (1) JP2005531545A (pt)
KR (1) KR20040107514A (pt)
CN (1) CN1286817C (pt)
AT (1) ATE330612T1 (pt)
AU (1) AU2003229729A1 (pt)
CA (1) CA2484585A1 (pt)
DE (1) DE60306361T2 (pt)
ES (1) ES2266811T3 (pt)
IT (1) ITMI20020934A1 (pt)
MX (1) MXPA04010774A (pt)
PL (1) PL373083A1 (pt)
PT (1) PT1501516E (pt)
WO (1) WO2003092698A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9133182B2 (en) * 2010-09-28 2015-09-15 Radius Health, Inc. Selective androgen receptor modulators
CN103012267B (zh) * 2012-10-11 2015-02-25 浙江大学 盐酸贝那普利结晶型物及其制备方法
CN105061312B (zh) * 2015-07-17 2017-12-12 惠州信立泰药业有限公司 一种改进的盐酸贝那普利的制备方法及含有该盐酸贝那普利的药物组合物
CN113292495B (zh) * 2021-06-18 2022-09-13 迪嘉药业集团有限公司 一种 (s)-氨基化合物的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4410520A (en) * 1981-11-09 1983-10-18 Ciba-Geigy Corporation 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
US4785089A (en) 1985-06-13 1988-11-15 Ciba-Geigy Corporation Novel sulfonic acid esters and their preparation

Also Published As

Publication number Publication date
ITMI20020934A0 (it) 2002-05-03
EP1501516A1 (en) 2005-02-02
CN1649594A (zh) 2005-08-03
EP1501516B1 (en) 2006-06-21
MXPA04010774A (es) 2005-07-05
CA2484585A1 (en) 2003-11-13
ATE330612T1 (de) 2006-07-15
CN1286817C (zh) 2006-11-29
KR20040107514A (ko) 2004-12-20
DE60306361D1 (de) 2006-08-03
JP2005531545A (ja) 2005-10-20
US20050203294A1 (en) 2005-09-15
ITMI20020934A1 (it) 2003-11-03
PL373083A1 (en) 2005-08-08
US6979736B2 (en) 2005-12-27
ES2266811T3 (es) 2007-03-01
DE60306361T2 (de) 2007-07-05
AU2003229729A1 (en) 2003-11-17
WO2003092698A1 (en) 2003-11-13

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