YU30203A - Kristalna venlafaksin baza i novi polimorfi venlafaksin hidrohlorida, postupci za njegovo pripremanje - Google Patents

Kristalna venlafaksin baza i novi polimorfi venlafaksin hidrohlorida, postupci za njegovo pripremanje

Info

Publication number
YU30203A
YU30203A YU30203A YUP30203A YU30203A YU 30203 A YU30203 A YU 30203A YU 30203 A YU30203 A YU 30203A YU P30203 A YUP30203 A YU P30203A YU 30203 A YU30203 A YU 30203A
Authority
YU
Yugoslavia
Prior art keywords
venlafaxine
preparing
processes
hydrochloride
novel
Prior art date
Application number
YU30203A
Other languages
English (en)
Inventor
Ben-Zion Dolitzky
Judith Aronhime
Schlomit Weizel
Genady Nisnevish
Original Assignee
Teva Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27500045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU30203(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Pharmaceutical Industries Ltd. filed Critical Teva Pharmaceutical Industries Ltd.
Publication of YU30203A publication Critical patent/YU30203A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Predmetni pronalazak odnosi se na novi esencijalno čist venlafaksin i postupak za njegovo pripremanje. Predmetni pronalazak takođe se odnosi na nove solvatne oblike venlafaksin hlorovodonika i postupak za njegovo pripremanje. Dalje, predmetni pronalazak obezbeđuje novi postupak za pripremanje venlafaksin hlorovodonika iz venlafaksina; postupak sadrži korake: i) pripremanje mešavine venlafaksina sa acetonom; i ii) izlaganje mešavine gasovitoj hlorovodoničnoj kiselini.[The present invention relates to novel essentially pure venlafaxine and the process of preparation thereof. The present invention also relates to novel solvate forms of venlafaxine hydrochloride and the process of preparation thereof. Furthermore, the present invention provides a novel process for preparing venlafaxine hydrochloride from venlafaxine; the process comprises the steps of: i) preparing a mixture of venlafaxine with acetone; and ii) exposing the mixture in gaseous hydrochoric acid.
YU30203A 2000-10-19 2001-10-19 Kristalna venlafaksin baza i novi polimorfi venlafaksin hidrohlorida, postupci za njegovo pripremanje YU30203A (sh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24157700P 2000-10-19 2000-10-19
US25886100P 2000-12-29 2000-12-29
US27872101P 2001-03-26 2001-03-26
US29246901P 2001-05-21 2001-05-21

Publications (1)

Publication Number Publication Date
YU30203A true YU30203A (sh) 2006-08-17

Family

ID=27500045

Family Applications (1)

Application Number Title Priority Date Filing Date
YU30203A YU30203A (sh) 2000-10-19 2001-10-19 Kristalna venlafaksin baza i novi polimorfi venlafaksin hidrohlorida, postupci za njegovo pripremanje

Country Status (20)

Country Link
US (1) US20020143211A1 (sh)
EP (1) EP1334082A4 (sh)
JP (2) JP2004530638A (sh)
KR (1) KR20030059206A (sh)
CN (1) CN1620420A (sh)
AU (1) AU2002241764A1 (sh)
CA (1) CA2426158A1 (sh)
CZ (1) CZ20031298A3 (sh)
DE (1) DE01988460T1 (sh)
ES (1) ES2206082T1 (sh)
HR (1) HRP20030392A2 (sh)
HU (1) HUP0303496A3 (sh)
IL (2) IL155400A0 (sh)
IS (1) IS6789A (sh)
MX (1) MXPA03003459A (sh)
NO (1) NO20031743L (sh)
PL (1) PL365895A1 (sh)
SK (1) SK5762003A3 (sh)
WO (1) WO2002045658A2 (sh)
YU (1) YU30203A (sh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020183553A1 (en) * 2000-10-19 2002-12-05 Ben-Zion Dolitzky Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
AU2002212340B2 (en) * 2000-10-31 2006-12-14 Sandoz Ag Crystalline forms of venlafaxine hydrochloride
HUP0104872A3 (en) * 2001-11-13 2004-04-28 Egis Gyogyszergyar Nyilvanosan New polymorphic forms of venlafaxine, process for their preparation, pharmaceutical compositions containing them and their use
UA77234C2 (en) * 2001-12-05 2006-11-15 Wyeth Corp Monohydrate of venlafaxine hydrochloride and methods for its preparation (variants)
MXPA04005305A (es) * 2001-12-05 2004-09-13 Wyeth Corp Nuevo polimorfo cristalino de clorhidrato de venlafaxina y metodos para preparacion del mismo.
WO2003050074A1 (en) * 2001-12-13 2003-06-19 Cadila Healthcare Limited Manufacture of venlafaxine hydrochloride and crystalline polymorphs thereof
AR039164A1 (es) 2002-03-28 2005-02-09 Synthon Bv Sales de venlafaxina de baja solubilidad en agua
US6717015B2 (en) 2002-03-28 2004-04-06 Synthon Bv Venlafaxine besylate
AU2003226748A1 (en) * 2002-03-28 2003-10-13 Synthon B.V. Compositions of venlafaxine base
DE10359154A1 (de) * 2003-12-16 2005-07-28 Krka Tovarna Zdravil, D.D. Verfahren zur Herstellung von Venlafaxin und Venlafaxinhydrochlorid der Form I
US7468428B2 (en) 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
WO2006043577A1 (ja) * 2004-10-20 2006-04-27 Mitsubishi Pharma Corporation フェニルエタノールアミン化合物の製造方法及びその中間体
JP2009511641A (ja) * 2005-10-19 2009-03-19 テバ ファーマシューティカル インダストリーズ リミティド 高純度１−〔２−ジメチルアミノ−（４−メトキシフェニル）エチル〕シクロヘキサノール塩酸塩の調製方法
WO2007049302A2 (en) * 2005-10-28 2007-05-03 Ind-Swift Laboratories Limited An improved process for the preparation of pure venlafaxine
EP2032521B1 (en) 2006-06-27 2009-10-28 Sandoz AG New method for salt preparation
AR062064A1 (es) * 2006-07-14 2008-10-15 Medichem Sa Prcesos mejorados para preparar una base de venlafaxina y sus sales
CN103588653B (zh) * 2010-10-01 2015-04-22 山东绿叶制药有限公司 4-甲基苯甲酸4-[2-二甲基胺基-1-(1-羟基环己基)乙基]苯酯盐酸盐的多晶型物、制备方法及其应用
CR20160222U (es) 2013-11-15 2016-08-26 Akebia Therapeutics Inc Formas solidas de acido { [ -(3- clorofenil) -3- hidroxipiridin -2-carbonil] amino} acetico, composiciones, y usos de las mismas

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535186A (en) * 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
US4611078A (en) * 1983-10-26 1986-09-09 American Home Products Corporation Substituted phenylacetonitriles
AR255595A1 (sh) 1994-07-13 2002-05-24 Gador Sa
PE57198A1 (es) * 1996-03-25 1998-10-10 American Home Prod Formula de liberacion prolongada
US6197828B1 (en) * 1998-12-01 2001-03-06 Sepracor, Inc. Derivatives of (+)-venlafaxine and methods of preparing and using the same
US20020183553A1 (en) * 2000-10-19 2002-12-05 Ben-Zion Dolitzky Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
AU2002212340B2 (en) * 2000-10-31 2006-12-14 Sandoz Ag Crystalline forms of venlafaxine hydrochloride
WO2002046140A1 (en) * 2000-12-07 2002-06-13 Dr. Reddy's Laboratories Ltd. Novel crystalline polymorphic forms of venlafaxine hydrochloride and a process for their preparation

Also Published As

Publication number Publication date
CZ20031298A3 (cs) 2003-10-15
CA2426158A1 (en) 2002-06-13
NO20031743D0 (no) 2003-04-15
AU2002241764A1 (en) 2002-06-18
EP1334082A4 (en) 2006-02-01
HUP0303496A3 (en) 2005-08-29
SK5762003A3 (en) 2003-11-04
WO2002045658A2 (en) 2002-06-13
ES2206082T1 (es) 2004-05-16
IL196287A0 (en) 2011-08-01
HUP0303496A2 (hu) 2004-01-28
JP2004530638A (ja) 2004-10-07
IL155400A0 (en) 2003-11-23
EP1334082A2 (en) 2003-08-13
IS6789A (is) 2003-04-15
PL365895A1 (en) 2005-01-10
NO20031743L (no) 2003-06-18
JP2008239629A (ja) 2008-10-09
DE01988460T1 (de) 2004-04-22
KR20030059206A (ko) 2003-07-07
WO2002045658A3 (en) 2003-01-16
HRP20030392A2 (en) 2005-04-30
US20020143211A1 (en) 2002-10-03
CN1620420A (zh) 2005-05-25
MXPA03003459A (es) 2005-04-29

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