HUP0201044A2 - Eljárás antibiotikus kompozitok előállítására - Google Patents

Eljárás antibiotikus kompozitok előállítására

Info

Publication number
HUP0201044A2
HUP0201044A2 HU0201044A HUP0201044A HUP0201044A2 HU P0201044 A2 HUP0201044 A2 HU P0201044A2 HU 0201044 A HU0201044 A HU 0201044A HU P0201044 A HUP0201044 A HU P0201044A HU P0201044 A2 HUP0201044 A2 HU P0201044A2
Authority
HU
Hungary
Prior art keywords
organic
antibiotic
preparation
composite components
pressing
Prior art date
Application number
HU0201044A
Other languages
English (en)
Inventor
Klaus-Dieter Kühn
Matthias Schnabelrauch
Sebastian Vogt
Original Assignee
Heraeus Kulzer Gmbh & Co. Kg.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heraeus Kulzer Gmbh & Co. Kg. filed Critical Heraeus Kulzer Gmbh & Co. Kg.
Publication of HU0201044D0 publication Critical patent/HU0201044D0/hu
Publication of HUP0201044A2 publication Critical patent/HUP0201044A2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Glanulating (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A találmány tárgya eljárás antibiotikus kompozitok előállítására,azzal jellemezve, hogy a plasztikusan alakítható só legalább egyprotonált antibiotikum bázis kationos komponenséből, melyet azaminoglükozid, lincosamid és tetraciklin típusú antibiotikumok közülválasztanak ki, és legalább egy anionos komponensből épül fel, melyeta szerves szulfátok és/vagy szerves szulfonátok és/vagyzsírsavészterek csoportjából választanak ki, ahol a szervetlenkompozit alkotók és/vagy a szerves kompozit alkotók rögzítéséhezkötőanyagként, és adott esetben vízzel keverés után a kompozitokalakjának kialakításához használják fel, ami főleg préseléssel,szalagpréssel, hengereléssel, kalanderezéssel és őrléssel történik. Ó
HU0201044A 2001-03-22 2002-03-21 Eljárás antibiotikus kompozitok előállítására HUP0201044A2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10114364A DE10114364A1 (de) 2001-03-22 2001-03-22 Verfahren zur Herstellung von antibiotischen Kompositen

Publications (2)

Publication Number Publication Date
HU0201044D0 HU0201044D0 (hu) 2002-05-29
HUP0201044A2 true HUP0201044A2 (hu) 2003-02-28

Family

ID=7678771

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0201044A HUP0201044A2 (hu) 2001-03-22 2002-03-21 Eljárás antibiotikus kompozitok előállítására

Country Status (29)

Country Link
US (1) US6942877B2 (hu)
EP (1) EP1243255B1 (hu)
JP (1) JP3950721B2 (hu)
CN (1) CN1221248C (hu)
AT (1) ATE311860T1 (hu)
AU (1) AU766912B2 (hu)
BG (1) BG65499B1 (hu)
BR (1) BR0201224A (hu)
CA (1) CA2378436C (hu)
CZ (1) CZ2002869A3 (hu)
DE (2) DE10114364A1 (hu)
DK (1) DK1243255T3 (hu)
EE (1) EE200200156A (hu)
ES (1) ES2249502T3 (hu)
GE (1) GEP20053449B (hu)
HR (1) HRP20020239B1 (hu)
HU (1) HUP0201044A2 (hu)
IL (1) IL148637A (hu)
MD (1) MD2517C2 (hu)
MX (1) MXPA02003004A (hu)
NO (1) NO20021391L (hu)
NZ (1) NZ517919A (hu)
PL (1) PL204984B1 (hu)
RU (1) RU2241490C2 (hu)
SA (1) SA02230035B1 (hu)
SK (1) SK286868B6 (hu)
UA (1) UA71992C2 (hu)
YU (1) YU18002A (hu)
ZA (1) ZA200202256B (hu)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10114245A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung
DE10262176B4 (de) 2002-06-21 2007-10-04 Heraeus Kulzer Gmbh Verfahren zur Herstellung von antibiotisch beschichteten porösen Körpern sowie Verwendung
DE10307103A1 (de) * 2003-02-19 2004-09-09 Schering Ag Antitumor wirksame 2-substituierte D-Homostra-1,3,5(10)-trien-3-yl sulfamate
DE10318991A1 (de) * 2003-04-25 2004-11-18 Heraeus Kulzer Gmbh & Co. Kg Poröser Körper mit antibiotischer Beschichtung, Verfahren zur Herstellung sowie Verwendung
DE102004060666B3 (de) 2004-12-15 2006-03-30 Heraeus Kulzer Gmbh Antibiotikum/Antibiotika enthaltendes Knochenersatzmaterial mit retardierender Wirkstofffreisetzung
DE102005002703C5 (de) * 2005-01-19 2013-07-04 Heraeus Kulzer Gmbh Antibiotische Beschichtung von Implantaten sowie Verfahren zur antibiotischen Beschichtung
DE102005061290B4 (de) * 2005-12-20 2021-03-18 Heraeus Medical Gmbh Verfahren zur Herstellung von Antibiotikum-/Antibiotika-Partikeln und deren Verwendung
US9603941B2 (en) * 2006-01-24 2017-03-28 Minghui Chai Method of preparing dendritic drugs
DE102006007245A1 (de) * 2006-02-15 2007-08-23 Heraeus Kulzer Gmbh Implantatmaterial
BRPI0602372B8 (pt) 2006-05-18 2021-06-22 Einco Biomaterial Ltda processo de preparação de compósitos em base de biocerâmicas e polímeros biodegradáveis e produto derivado
WO2008006083A2 (en) 2006-07-07 2008-01-10 Surmodics, Inc. Beaded wound spacer device
US20080063681A1 (en) * 2006-09-11 2008-03-13 Ebi, L.P. Therapeutic bone replacement material
DE602006005054D1 (de) * 2006-09-19 2009-03-19 Leibniz Inst Naturstoff Forsch Antibiotikum Maduraphthalazin-Salze mit verzögerter Wirkstofffreigabe des Wirkstoffs und deren Verwendung
DE102006060938A1 (de) * 2006-12-20 2008-06-26 Wolter, Dietmar F., Prof. Dr. Materialdepot zur Abgabe eines antibakteriellen Wirkstoffmaterials
DE102007039871A1 (de) * 2007-08-21 2009-02-26 Friedrich-Baur-Gmbh Weichgewebe-Implantat mit antibakterieller Wirkung
JP6298468B2 (ja) 2012-10-16 2018-03-20 サーモディクス，インコーポレイテッド 創傷充填デバイスおよび方法
RU2535067C1 (ru) * 2013-08-19 2014-12-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Саратовский государственный аграрный университет имени Н.И. Вавилова" Биоинтегрируемый композитный материал и способ формирования покрытия на изделиях медицинского назначения с использованием биоинтегрируемого композитного материала
US10201457B2 (en) 2014-08-01 2019-02-12 Surmodics, Inc. Wound packing device with nanotextured surface
CN106721083A (zh) * 2016-12-21 2017-05-31 驻马店华中正大有限公司 一种土霉素预混剂及其制备方法
RU2729025C1 (ru) * 2019-07-19 2020-08-03 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр травматологии и ортопедии имени Н.Н. Приорова" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ТО им. Н.Н. Приорова" Минздрава России) Способ хирургического лечения гнойно-воспалительных процессов костных и мягкотканых структур опорно-двигательной системы пациента с использованием мягких спейсеров, импрегнированных антибактериальными средствами

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE115001C (hu)
US1059684A (en) * 1912-09-20 1913-04-22 Eagle Lock Co Multiple-key lock.
US3022286A (en) * 1959-12-14 1962-02-20 S B Penick And Company Process for preparing higher fatty acid salts of neomycin
US3091572A (en) * 1962-07-16 1963-05-28 Schering Corp Gentamycin and method of production
GB1046332A (en) * 1963-03-04 1966-10-19 Upjohn Co Salts of the antibiotic lincomycin
ES315101A1 (es) * 1965-07-08 1966-01-01 Folch Vazquez Conrado Procedimiento de preparaciën de nuevos derivados de tetraciclina
FR6476M (hu) * 1967-06-06 1968-11-18
DE2320373B2 (de) * 1973-04-21 1978-04-06 Merck Patent Gmbh, 6100 Darmstadt Antibioticahaltiges Mittel und seine Verwendung als chirurgisches Kunststoffmaterial
US3883858A (en) * 1973-12-17 1975-05-13 Ampex Magnetoresistive readout transducer for sensing magnetic domains in thin film memories
FR2272680B1 (hu) * 1974-05-29 1978-07-21 Hosbon Sa Lab
DE2511122B2 (de) * 1975-03-14 1977-06-08 Vorprodukt fuer die zubereitung von knochenzement
AR216922A1 (es) * 1976-11-11 1980-02-15 Merck Patent Gmbh Procedimiento para la fabricacion de un medio quirurgico
DE2843963A1 (de) * 1978-10-09 1980-04-24 Merck Patent Gmbh Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin
DE3206725A1 (de) * 1981-05-13 1982-12-02 Merck Patent Gmbh, 6100 Darmstadt Schwer loesliche salze von aminoglykosidantibiotika
JPS5943520B2 (ja) * 1981-10-16 1984-10-22 富士化成株式会社 乾式掃除剤
DE3248328A1 (de) * 1982-12-28 1984-06-28 Bayer Ag, 5090 Leverkusen Schwerloesliche salze von aminoglykosiden sowie diese enthaltende formulierungen mit verzoegerter wirkstoff-freigabe
US6077822A (en) * 1993-09-14 2000-06-20 Dumex-Alpharma A/S Drug salts
DE4404018A1 (de) * 1994-02-09 1995-08-10 Merck Patent Gmbh Protrahiert freisetzende Darreichungsformen enthaltend Clindamycin-Palmitat
WO1995027517A1 (fr) 1994-04-06 1995-10-19 Lyzion Australia Pty. Ltd. Preparation pharmaceutique pour application locale, et procede de fabrication
US5614206A (en) * 1995-03-07 1997-03-25 Wright Medical Technology, Inc. Controlled dissolution pellet containing calcium sulfate
US5670142A (en) * 1996-07-08 1997-09-23 Donald Neudecker Treatment for itch of chicken pox
DE19713229A1 (de) * 1997-04-01 1998-10-08 Merck Patent Gmbh Antibiotikumhaltige Knochenzementpaste
US5874418A (en) * 1997-05-05 1999-02-23 Cydex, Inc. Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use

Also Published As

Publication number Publication date
CN1221248C (zh) 2005-10-05
PL352923A1 (en) 2002-09-23
IL148637A0 (en) 2002-09-12
CA2378436C (en) 2007-12-18
EP1243255A2 (de) 2002-09-25
CA2378436A1 (en) 2002-09-22
IL148637A (en) 2006-10-31
US20020192279A1 (en) 2002-12-19
DK1243255T3 (da) 2006-03-27
JP2002338472A (ja) 2002-11-27
CN1376459A (zh) 2002-10-30
DE10114364A1 (de) 2002-10-02
MD20020074A (en) 2002-11-30
MD2517C2 (ro) 2005-03-31
MD2517B2 (en) 2004-08-31
EP1243255A3 (de) 2002-12-18
AU2755702A (en) 2002-09-26
CZ2002869A3 (cs) 2002-11-13
HRP20020239A2 (en) 2002-12-31
UA71992C2 (en) 2005-01-17
SA02230035B1 (ar) 2007-04-15
RU2241490C2 (ru) 2004-12-10
DE50205147D1 (de) 2006-01-12
NO20021391D0 (no) 2002-03-20
HRP20020239B1 (en) 2006-12-31
EP1243255B1 (de) 2005-12-07
GEP20053449B (en) 2005-02-25
JP3950721B2 (ja) 2007-08-01
NO20021391L (no) 2002-09-23
AU766912B2 (en) 2003-10-23
BG106457A (en) 2002-10-31
MXPA02003004A (es) 2003-08-20
ZA200202256B (en) 2002-10-11
PL204984B1 (pl) 2010-02-26
BR0201224A (pt) 2002-12-10
ES2249502T3 (es) 2006-04-01
ATE311860T1 (de) 2005-12-15
EE200200156A (et) 2002-12-16
NZ517919A (en) 2003-08-29
SK286868B6 (sk) 2009-06-05
YU18002A (sh) 2004-11-25
BG65499B1 (bg) 2008-10-31
HU0201044D0 (hu) 2002-05-29
US6942877B2 (en) 2005-09-13
SK3942002A3 (en) 2002-10-08

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