NO20064988L - Ny krystallinsk form av 8-cyano-1-cyklopropyl-7-(1 S,6S-2,8-diazabicyklo[4.3 0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-okso-3-quinolinkarboksylsyre - Google Patents

Ny krystallinsk form av 8-cyano-1-cyklopropyl-7-(1 S,6S-2,8-diazabicyklo[4.3 0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-okso-3-quinolinkarboksylsyre

Info

Publication number
NO20064988L
NO20064988L NO20064988A NO20064988A NO20064988L NO 20064988 L NO20064988 L NO 20064988L NO 20064988 A NO20064988 A NO 20064988A NO 20064988 A NO20064988 A NO 20064988A NO 20064988 L NO20064988 L NO 20064988L
Authority
NO
Norway
Prior art keywords
nonan
diazabicyclo
cyclopropyl
dihydro
oxo
Prior art date
Application number
NO20064988A
Other languages
English (en)
Other versions
NO337279B1 (no
Inventor
Alfons Grunenberg
Hubert Rast
Iris Heep
Werner Hallenbach
Jordi Benet-Buchholz
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Publication of NO20064988L publication Critical patent/NO20064988L/no
Publication of NO337279B1 publication Critical patent/NO337279B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

Foreliggende oppfinnelse angår trihydratet av pradofloksacin, en fremgangsmåte for dets fremstilling og antibakterielle sammensetninger som inneholder dem.
NO20064988A 2004-04-01 2006-10-31 Ny krystallinsk form av 8-cyano-1-cyklopropyl-7-((1S,6S)-2,8-diazabicyklo[4.3 0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-okso-3-quinolinkarboksylsyre, medikamenter som inneholder denne, og anvendelse derav. NO337279B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004015981A DE102004015981A1 (de) 2004-04-01 2004-04-01 Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
PCT/EP2005/002953 WO2005097789A1 (de) 2004-04-01 2005-03-19 Neue kristalline form von 8-cyan-1-cyclopropyl-7-(1s,6s-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure

Publications (2)

Publication Number Publication Date
NO20064988L true NO20064988L (no) 2006-10-31
NO337279B1 NO337279B1 (no) 2016-02-29

Family

ID=34962324

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20064988A NO337279B1 (no) 2004-04-01 2006-10-31 Ny krystallinsk form av 8-cyano-1-cyklopropyl-7-((1S,6S)-2,8-diazabicyklo[4.3 0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-okso-3-quinolinkarboksylsyre, medikamenter som inneholder denne, og anvendelse derav.

Country Status (32)

Country Link
US (1) US7977484B2 (no)
EP (1) EP1737859B1 (no)
JP (1) JP5190259B2 (no)
KR (1) KR101217678B1 (no)
CN (1) CN100591681C (no)
AR (2) AR048099A1 (no)
AT (1) ATE450536T1 (no)
AU (1) AU2005231918B2 (no)
BR (1) BRPI0509529B8 (no)
CA (1) CA2561635C (no)
CY (2) CY1109762T1 (no)
DE (3) DE102004015981A1 (no)
DK (1) DK1737859T3 (no)
ES (1) ES2335899T3 (no)
GT (1) GT200500043A (no)
HK (1) HK1104537A1 (no)
HR (1) HRP20100097T1 (no)
IL (1) IL178353A (no)
MY (1) MY140998A (no)
NO (1) NO337279B1 (no)
NZ (1) NZ550226A (no)
PE (1) PE20060170A1 (no)
PL (1) PL1737859T3 (no)
PT (1) PT1737859E (no)
RU (1) RU2383543C2 (no)
SI (1) SI1737859T1 (no)
SV (1) SV2006002070A (no)
TW (1) TWI350755B (no)
UA (1) UA84329C2 (no)
UY (1) UY28828A1 (no)
WO (1) WO2005097789A1 (no)
ZA (1) ZA200608072B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006010642A1 (de) * 2006-03-08 2007-09-27 Bayer Healthcare Aktiengesellschaft Arzneimittelformulierungen, enthaltend Fluorchinolone
DE102006010643A1 (de) 2006-03-08 2007-09-13 Bayer Healthcare Aktiengesellschaft Arzneimittel enthaltend Fluorchinolone
DE102007026550A1 (de) * 2007-06-08 2008-12-11 Bayer Healthcare Ag Extrudate mit verbesserter Geschmacksmaskierung
PE20191462A1 (es) 2017-02-13 2019-10-16 Bayer Animal Health Gmbh Composicion liquida que contiene pradofloxacina
CN115710267A (zh) * 2022-11-30 2023-02-24 天津大学 一种普拉沙星水合物晶体及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9707606B1 (pt) 1996-02-23 2010-08-10 ácidos 8-ciano-1-ciclopropil-7-(2,8-diazabiciclo(4.3.0) nonan-8-il)-6-flúor-1,4-diidro-4-oxo-3-quinolinocarbo xìlicos, bem como medicamentos que os compreendem.
DE19854356A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908448A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure
DE19908449A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
US6627646B2 (en) * 2001-07-17 2003-09-30 Sepracor Inc. Norastemizole polymorphs

Also Published As

Publication number Publication date
BRPI0509529A (pt) 2007-09-18
KR101217678B1 (ko) 2013-01-02
US20080125458A1 (en) 2008-05-29
AR105177A2 (es) 2017-09-13
US7977484B2 (en) 2011-07-12
ATE450536T1 (de) 2009-12-15
CY1109762T1 (el) 2014-09-10
DE502005008620D1 (de) 2010-01-14
ZA200608072B (en) 2008-01-08
JP5190259B2 (ja) 2013-04-24
SV2006002070A (es) 2006-03-15
ES2335899T3 (es) 2010-04-06
CN1938304A (zh) 2007-03-28
TW200602053A (en) 2006-01-16
HK1104537A1 (en) 2008-01-18
CN100591681C (zh) 2010-02-24
PT1737859E (pt) 2010-02-03
AU2005231918B2 (en) 2011-05-12
BRPI0509529B8 (pt) 2021-05-25
RU2006138362A (ru) 2008-05-10
DE122011100055I1 (de) 2012-03-15
EP1737859B1 (de) 2009-12-02
IL178353A (en) 2011-08-31
AU2005231918A1 (en) 2005-10-20
HRP20100097T1 (hr) 2010-04-30
TWI350755B (en) 2011-10-21
NZ550226A (en) 2009-11-27
NO337279B1 (no) 2016-02-29
CA2561635A1 (en) 2005-10-20
DE102004015981A1 (de) 2005-10-20
AR048099A1 (es) 2006-03-29
DK1737859T3 (da) 2010-04-06
BRPI0509529B1 (pt) 2019-05-21
GT200500043A (es) 2006-02-17
UY28828A1 (es) 2005-11-30
PE20060170A1 (es) 2006-04-13
WO2005097789A1 (de) 2005-10-20
SI1737859T1 (sl) 2010-03-31
CA2561635C (en) 2012-10-16
KR20070014157A (ko) 2007-01-31
RU2383543C2 (ru) 2010-03-10
PL1737859T3 (pl) 2010-04-30
JP2007530614A (ja) 2007-11-01
MY140998A (en) 2010-02-12
CY2011018I1 (el) 2016-12-14
UA84329C2 (en) 2008-10-10
EP1737859A1 (de) 2007-01-03
IL178353A0 (en) 2007-02-11

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Legal Events

Date Code Title Description
CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: BAYER INTELLECTUAL PROPERTY GMBH, DE

CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: ELANCO ANIMAL HEALTH GMBH, DE