UA84329C2 - Crystalline form of 8-cyano-1-cyclopropyl-7-(1s,6s-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid - Google Patents

Crystalline form of 8-cyano-1-cyclopropyl-7-(1s,6s-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid

Info

Publication number
UA84329C2
UA84329C2 UAA200611491A UAA200611491A UA84329C2 UA 84329 C2 UA84329 C2 UA 84329C2 UA A200611491 A UAA200611491 A UA A200611491A UA A200611491 A UAA200611491 A UA A200611491A UA 84329 C2 UA84329 C2 UA 84329C2
Authority
UA
Ukraine
Prior art keywords
nonan
diazabicyclo
cyclopropyl
dihydro
oxo
Prior art date
Application number
UAA200611491A
Other languages
English (en)
Ukrainian (uk)
Inventor
Хуберт Раст
Ирис Хеэп
Альфонс Груненберг
Вернер Халленбах
Хорди Бенет-Буххольц
Original Assignee
Байер Хэлскер Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Байер Хэлскер Аг filed Critical Байер Хэлскер Аг
Publication of UA84329C2 publication Critical patent/UA84329C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Данное изобретение касается тригидрата прадофлоксацина, (I)способа его получения, а также антибактериального средства, которое он содержит.
UAA200611491A 2004-04-01 2005-03-19 Crystalline form of 8-cyano-1-cyclopropyl-7-(1s,6s-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid UA84329C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004015981A DE102004015981A1 (de) 2004-04-01 2004-04-01 Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
PCT/EP2005/002953 WO2005097789A1 (de) 2004-04-01 2005-03-19 Neue kristalline form von 8-cyan-1-cyclopropyl-7-(1s,6s-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure

Publications (1)

Publication Number Publication Date
UA84329C2 true UA84329C2 (en) 2008-10-10

Family

ID=34962324

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200611491A UA84329C2 (en) 2004-04-01 2005-03-19 Crystalline form of 8-cyano-1-cyclopropyl-7-(1s,6s-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid

Country Status (32)

Country Link
US (1) US7977484B2 (ru)
EP (1) EP1737859B1 (ru)
JP (1) JP5190259B2 (ru)
KR (1) KR101217678B1 (ru)
CN (1) CN100591681C (ru)
AR (2) AR048099A1 (ru)
AT (1) ATE450536T1 (ru)
AU (1) AU2005231918B2 (ru)
BR (1) BRPI0509529B8 (ru)
CA (1) CA2561635C (ru)
CY (2) CY1109762T1 (ru)
DE (3) DE102004015981A1 (ru)
DK (1) DK1737859T3 (ru)
ES (1) ES2335899T3 (ru)
GT (1) GT200500043A (ru)
HK (1) HK1104537A1 (ru)
HR (1) HRP20100097T1 (ru)
IL (1) IL178353A (ru)
MY (1) MY140998A (ru)
NO (1) NO337279B1 (ru)
NZ (1) NZ550226A (ru)
PE (1) PE20060170A1 (ru)
PL (1) PL1737859T3 (ru)
PT (1) PT1737859E (ru)
RU (1) RU2383543C2 (ru)
SI (1) SI1737859T1 (ru)
SV (1) SV2006002070A (ru)
TW (1) TWI350755B (ru)
UA (1) UA84329C2 (ru)
UY (1) UY28828A1 (ru)
WO (1) WO2005097789A1 (ru)
ZA (1) ZA200608072B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006010642A1 (de) * 2006-03-08 2007-09-27 Bayer Healthcare Aktiengesellschaft Arzneimittelformulierungen, enthaltend Fluorchinolone
DE102006010643A1 (de) 2006-03-08 2007-09-13 Bayer Healthcare Aktiengesellschaft Arzneimittel enthaltend Fluorchinolone
DE102007026550A1 (de) * 2007-06-08 2008-12-11 Bayer Healthcare Ag Extrudate mit verbesserter Geschmacksmaskierung
EP3579820B1 (en) 2017-02-13 2021-04-28 Bayer Animal Health GmbH Liquid composition containing pradofloxacin
CN115710267A (zh) * 2022-11-30 2023-02-24 天津大学 一种普拉沙星水合物晶体及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0882049B1 (de) 1996-02-23 2002-11-20 Bayer Ag Gegebenenfalls substituierte 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo- 4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre derivate
DE19854355A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854357A1 (de) 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854356A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
DE19908448A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure
US6627646B2 (en) * 2001-07-17 2003-09-30 Sepracor Inc. Norastemizole polymorphs

Also Published As

Publication number Publication date
WO2005097789A1 (de) 2005-10-20
HRP20100097T1 (hr) 2010-04-30
IL178353A (en) 2011-08-31
ZA200608072B (en) 2008-01-08
DK1737859T3 (da) 2010-04-06
ATE450536T1 (de) 2009-12-15
CY1109762T1 (el) 2014-09-10
EP1737859B1 (de) 2009-12-02
TWI350755B (en) 2011-10-21
BRPI0509529B1 (pt) 2019-05-21
PT1737859E (pt) 2010-02-03
US7977484B2 (en) 2011-07-12
RU2006138362A (ru) 2008-05-10
CY2011018I1 (el) 2016-12-14
DE122011100055I1 (de) 2012-03-15
BRPI0509529B8 (pt) 2021-05-25
AU2005231918A1 (en) 2005-10-20
UY28828A1 (es) 2005-11-30
AR105177A2 (es) 2017-09-13
IL178353A0 (en) 2007-02-11
PE20060170A1 (es) 2006-04-13
AU2005231918B2 (en) 2011-05-12
BRPI0509529A (pt) 2007-09-18
DE102004015981A1 (de) 2005-10-20
DE502005008620D1 (de) 2010-01-14
CN100591681C (zh) 2010-02-24
US20080125458A1 (en) 2008-05-29
RU2383543C2 (ru) 2010-03-10
NZ550226A (en) 2009-11-27
KR20070014157A (ko) 2007-01-31
KR101217678B1 (ko) 2013-01-02
CN1938304A (zh) 2007-03-28
JP5190259B2 (ja) 2013-04-24
SV2006002070A (es) 2006-03-15
CA2561635A1 (en) 2005-10-20
HK1104537A1 (en) 2008-01-18
ES2335899T3 (es) 2010-04-06
NO20064988L (no) 2006-10-31
EP1737859A1 (de) 2007-01-03
SI1737859T1 (sl) 2010-03-31
AR048099A1 (es) 2006-03-29
PL1737859T3 (pl) 2010-04-30
NO337279B1 (no) 2016-02-29
TW200602053A (en) 2006-01-16
GT200500043A (es) 2006-02-17
CA2561635C (en) 2012-10-16
MY140998A (en) 2010-02-12
JP2007530614A (ja) 2007-11-01

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