MD2517C2 - Procedeu de producere a compozitelor antibiotice si utilizarea lor - Google Patents
Procedeu de producere a compozitelor antibiotice si utilizarea lorInfo
- Publication number
- MD2517C2 MD2517C2 MDA20020074A MD20020074A MD2517C2 MD 2517 C2 MD2517 C2 MD 2517C2 MD A20020074 A MDA20020074 A MD A20020074A MD 20020074 A MD20020074 A MD 20020074A MD 2517 C2 MD2517 C2 MD 2517C2
- Authority
- MD
- Moldova
- Prior art keywords
- antibiotics
- composite
- organic
- production
- composites
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Glanulating (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Invenţia se referă la un procedeu de producere a compozitelor antibiotice, care pot fi utilizate ca implanturi în medicină şi în medicina veterinară pentru tratamentul infecţiilor microbiene locale din ţesuturile tari sau moi.Procedeul constă în aceea că fixarea componentelor anorganice şi/sau organice ale compozitelor şi respectiv modelarea compozitelor la amestecarea cu apă se efectuează cu un liant, care reprezintă o sare deformabilă plastic constituită din cel puţin un component cationic al unui antibiotic protonat din grupa de aminoglicozide, lincosamide şi tetracicline şi cel puţin un component anionic din grupa de sulfaţi organici şi/sau sulfonaţi organici şi/sau esteri ai acizilor graşi, în special prin presare, extruziune, vălţuire, calandrare.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10114364A DE10114364A1 (de) | 2001-03-22 | 2001-03-22 | Verfahren zur Herstellung von antibiotischen Kompositen |
Publications (3)
Publication Number | Publication Date |
---|---|
MD20020074A MD20020074A (ro) | 2002-11-30 |
MD2517B2 MD2517B2 (ro) | 2004-08-31 |
MD2517C2 true MD2517C2 (ro) | 2005-03-31 |
Family
ID=7678771
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MDA20020074A MD2517C2 (ro) | 2001-03-22 | 2002-02-13 | Procedeu de producere a compozitelor antibiotice si utilizarea lor |
Country Status (29)
Country | Link |
---|---|
US (1) | US6942877B2 (ro) |
EP (1) | EP1243255B1 (ro) |
JP (1) | JP3950721B2 (ro) |
CN (1) | CN1221248C (ro) |
AT (1) | ATE311860T1 (ro) |
AU (1) | AU766912B2 (ro) |
BG (1) | BG65499B1 (ro) |
BR (1) | BR0201224A (ro) |
CA (1) | CA2378436C (ro) |
CZ (1) | CZ2002869A3 (ro) |
DE (2) | DE10114364A1 (ro) |
DK (1) | DK1243255T3 (ro) |
EE (1) | EE200200156A (ro) |
ES (1) | ES2249502T3 (ro) |
GE (1) | GEP20053449B (ro) |
HR (1) | HRP20020239B1 (ro) |
HU (1) | HUP0201044A2 (ro) |
IL (1) | IL148637A (ro) |
MD (1) | MD2517C2 (ro) |
MX (1) | MXPA02003004A (ro) |
NO (1) | NO20021391L (ro) |
NZ (1) | NZ517919A (ro) |
PL (1) | PL204984B1 (ro) |
RU (1) | RU2241490C2 (ro) |
SA (1) | SA02230035B1 (ro) |
SK (1) | SK286868B6 (ro) |
UA (1) | UA71992C2 (ro) |
YU (1) | YU18002A (ro) |
ZA (1) | ZA200202256B (ro) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10114245A1 (de) * | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung |
DE10227935B4 (de) * | 2002-06-21 | 2007-10-04 | Heraeus Kulzer Gmbh | Verfahren zur Herstellung einer antibiotische Beschichtung von porösen Körpern sowie Verwendung |
DE10307103A1 (de) * | 2003-02-19 | 2004-09-09 | Schering Ag | Antitumor wirksame 2-substituierte D-Homostra-1,3,5(10)-trien-3-yl sulfamate |
DE10318991A1 (de) * | 2003-04-25 | 2004-11-18 | Heraeus Kulzer Gmbh & Co. Kg | Poröser Körper mit antibiotischer Beschichtung, Verfahren zur Herstellung sowie Verwendung |
DE102004060666B3 (de) | 2004-12-15 | 2006-03-30 | Heraeus Kulzer Gmbh | Antibiotikum/Antibiotika enthaltendes Knochenersatzmaterial mit retardierender Wirkstofffreisetzung |
DE102005002703C5 (de) | 2005-01-19 | 2013-07-04 | Heraeus Kulzer Gmbh | Antibiotische Beschichtung von Implantaten sowie Verfahren zur antibiotischen Beschichtung |
DE102005061290B4 (de) * | 2005-12-20 | 2021-03-18 | Heraeus Medical Gmbh | Verfahren zur Herstellung von Antibiotikum-/Antibiotika-Partikeln und deren Verwendung |
US9603941B2 (en) * | 2006-01-24 | 2017-03-28 | Minghui Chai | Method of preparing dendritic drugs |
DE102006007245A1 (de) * | 2006-02-15 | 2007-08-23 | Heraeus Kulzer Gmbh | Implantatmaterial |
BRPI0602372B8 (pt) | 2006-05-18 | 2021-06-22 | Einco Biomaterial Ltda | processo de preparação de compósitos em base de biocerâmicas e polímeros biodegradáveis e produto derivado |
WO2008006083A2 (en) | 2006-07-07 | 2008-01-10 | Surmodics, Inc. | Beaded wound spacer device |
US20080063681A1 (en) * | 2006-09-11 | 2008-03-13 | Ebi, L.P. | Therapeutic bone replacement material |
ATE421956T1 (de) * | 2006-09-19 | 2009-02-15 | Leibniz Inst Naturstoff Forsch | Antibiotikum maduraphthalazin-salze mit verzögerter wirkstofffreigabe des wirkstoffs und deren verwendung |
DE102006060938A1 (de) * | 2006-12-20 | 2008-06-26 | Wolter, Dietmar F., Prof. Dr. | Materialdepot zur Abgabe eines antibakteriellen Wirkstoffmaterials |
DE102007039871A1 (de) | 2007-08-21 | 2009-02-26 | Friedrich-Baur-Gmbh | Weichgewebe-Implantat mit antibakterieller Wirkung |
CA2888241C (en) | 2012-10-16 | 2020-12-29 | Surmodics, Inc. | Wound packing device and methods |
RU2535067C1 (ru) * | 2013-08-19 | 2014-12-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Саратовский государственный аграрный университет имени Н.И. Вавилова" | Биоинтегрируемый композитный материал и способ формирования покрытия на изделиях медицинского назначения с использованием биоинтегрируемого композитного материала |
US10201457B2 (en) | 2014-08-01 | 2019-02-12 | Surmodics, Inc. | Wound packing device with nanotextured surface |
CN106721083A (zh) * | 2016-12-21 | 2017-05-31 | 驻马店华中正大有限公司 | 一种土霉素预混剂及其制备方法 |
RU2729025C1 (ru) * | 2019-07-19 | 2020-08-03 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр травматологии и ортопедии имени Н.Н. Приорова" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ТО им. Н.Н. Приорова" Минздрава России) | Способ хирургического лечения гнойно-воспалительных процессов костных и мягкотканых структур опорно-двигательной системы пациента с использованием мягких спейсеров, импрегнированных антибактериальными средствами |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3536759A (en) * | 1967-06-06 | 1970-10-27 | Lab Hosbon Sa | Tetracycline sulfamate and derivatives thereof |
DE3248328A1 (de) * | 1982-12-28 | 1984-06-28 | Bayer Ag, 5090 Leverkusen | Schwerloesliche salze von aminoglykosiden sowie diese enthaltende formulierungen mit verzoegerter wirkstoff-freigabe |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE115001C (ro) | ||||
US1059684A (en) * | 1912-09-20 | 1913-04-22 | Eagle Lock Co | Multiple-key lock. |
US3022286A (en) * | 1959-12-14 | 1962-02-20 | S B Penick And Company | Process for preparing higher fatty acid salts of neomycin |
US3091572A (en) * | 1962-07-16 | 1963-05-28 | Schering Corp | Gentamycin and method of production |
GB1046332A (en) * | 1963-03-04 | 1966-10-19 | Upjohn Co | Salts of the antibiotic lincomycin |
ES315101A1 (es) * | 1965-07-08 | 1966-01-01 | Folch Vazquez Conrado | Procedimiento de preparaciën de nuevos derivados de tetraciclina |
DE2320373B2 (de) * | 1973-04-21 | 1978-04-06 | Merck Patent Gmbh, 6100 Darmstadt | Antibioticahaltiges Mittel und seine Verwendung als chirurgisches Kunststoffmaterial |
US3883858A (en) * | 1973-12-17 | 1975-05-13 | Ampex | Magnetoresistive readout transducer for sensing magnetic domains in thin film memories |
FR2272680B1 (ro) * | 1974-05-29 | 1978-07-21 | Hosbon Sa Lab | |
DE2511122B2 (de) * | 1975-03-14 | 1977-06-08 | Vorprodukt fuer die zubereitung von knochenzement | |
AR216922A1 (es) * | 1976-11-11 | 1980-02-15 | Merck Patent Gmbh | Procedimiento para la fabricacion de un medio quirurgico |
DE2843963A1 (de) * | 1978-10-09 | 1980-04-24 | Merck Patent Gmbh | Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin |
DE3206725A1 (de) * | 1981-05-13 | 1982-12-02 | Merck Patent Gmbh, 6100 Darmstadt | Schwer loesliche salze von aminoglykosidantibiotika |
JPS5943520B2 (ja) * | 1981-10-16 | 1984-10-22 | 富士化成株式会社 | 乾式掃除剤 |
US6077822A (en) * | 1993-09-14 | 2000-06-20 | Dumex-Alpharma A/S | Drug salts |
DE4404018A1 (de) * | 1994-02-09 | 1995-08-10 | Merck Patent Gmbh | Protrahiert freisetzende Darreichungsformen enthaltend Clindamycin-Palmitat |
AU6439094A (en) | 1994-04-06 | 1995-10-30 | Aktsionernoe Obschestvo Zakrytogo Tipa Firma "Assol" (Firma "Assol") | Pharmaceutical agent for local application and a method of obtaining same |
US5614206A (en) * | 1995-03-07 | 1997-03-25 | Wright Medical Technology, Inc. | Controlled dissolution pellet containing calcium sulfate |
US5670142A (en) * | 1996-07-08 | 1997-09-23 | Donald Neudecker | Treatment for itch of chicken pox |
DE19713229A1 (de) * | 1997-04-01 | 1998-10-08 | Merck Patent Gmbh | Antibiotikumhaltige Knochenzementpaste |
US5874418A (en) * | 1997-05-05 | 1999-02-23 | Cydex, Inc. | Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use |
-
2001
- 2001-03-22 DE DE10114364A patent/DE10114364A1/de not_active Withdrawn
-
2002
- 2002-02-13 MD MDA20020074A patent/MD2517C2/ro not_active IP Right Cessation
- 2002-02-19 GE GE4982A patent/GEP20053449B/en unknown
- 2002-02-27 BG BG106457A patent/BG65499B1/bg unknown
- 2002-03-06 DK DK02005025T patent/DK1243255T3/da active
- 2002-03-06 ES ES02005025T patent/ES2249502T3/es not_active Expired - Lifetime
- 2002-03-06 DE DE50205147T patent/DE50205147D1/de not_active Expired - Lifetime
- 2002-03-06 AT AT02005025T patent/ATE311860T1/de not_active IP Right Cessation
- 2002-03-06 EP EP02005025A patent/EP1243255B1/de not_active Expired - Lifetime
- 2002-03-08 CZ CZ2002869A patent/CZ2002869A3/cs unknown
- 2002-03-12 IL IL148637A patent/IL148637A/en not_active IP Right Cessation
- 2002-03-13 YU YU18002A patent/YU18002A/sh unknown
- 2002-03-19 US US10/100,843 patent/US6942877B2/en not_active Expired - Fee Related
- 2002-03-19 SK SK394-2002A patent/SK286868B6/sk not_active IP Right Cessation
- 2002-03-19 JP JP2002076627A patent/JP3950721B2/ja not_active Expired - Fee Related
- 2002-03-20 ZA ZA200202256A patent/ZA200202256B/xx unknown
- 2002-03-20 NO NO20021391A patent/NO20021391L/no not_active Application Discontinuation
- 2002-03-20 MX MXPA02003004A patent/MXPA02003004A/es active IP Right Grant
- 2002-03-21 HU HU0201044A patent/HUP0201044A2/hu unknown
- 2002-03-21 UA UA2002032261A patent/UA71992C2/uk unknown
- 2002-03-21 PL PL352923A patent/PL204984B1/pl not_active IP Right Cessation
- 2002-03-21 RU RU2002107211/15A patent/RU2241490C2/ru not_active IP Right Cessation
- 2002-03-21 NZ NZ517919A patent/NZ517919A/en unknown
- 2002-03-21 HR HR20020239A patent/HRP20020239B1/xx not_active IP Right Cessation
- 2002-03-21 AU AU27557/02A patent/AU766912B2/en not_active Ceased
- 2002-03-22 CN CNB021079765A patent/CN1221248C/zh not_active Expired - Fee Related
- 2002-03-22 BR BR0201224-3A patent/BR0201224A/pt not_active IP Right Cessation
- 2002-03-22 EE EEP200200156A patent/EE200200156A/xx unknown
- 2002-03-22 CA CA002378436A patent/CA2378436C/en not_active Expired - Fee Related
- 2002-04-02 SA SA02230035A patent/SA02230035B1/ar unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3536759A (en) * | 1967-06-06 | 1970-10-27 | Lab Hosbon Sa | Tetracycline sulfamate and derivatives thereof |
DE3248328A1 (de) * | 1982-12-28 | 1984-06-28 | Bayer Ag, 5090 Leverkusen | Schwerloesliche salze von aminoglykosiden sowie diese enthaltende formulierungen mit verzoegerter wirkstoff-freigabe |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) | ||
MM4A | Patent for invention definitely lapsed due to non-payment of fees |