HUP0104120A2 - Eljárás alfa-arilalkánsav-származékok előállítására - Google Patents
Eljárás alfa-arilalkánsav-származékok előállításáraInfo
- Publication number
- HUP0104120A2 HUP0104120A2 HU0104120A HUP0104120A HUP0104120A2 HU P0104120 A2 HUP0104120 A2 HU P0104120A2 HU 0104120 A HU0104120 A HU 0104120A HU P0104120 A HUP0104120 A HU P0104120A HU P0104120 A2 HUP0104120 A2 HU P0104120A2
- Authority
- HU
- Hungary
- Prior art keywords
- compound
- general formula
- formula
- preparation
- alpha
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 239000002253 acid Substances 0.000 title abstract 2
- 150000007513 acids Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 8
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000000636 p-nitrophenyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1*)[N+]([O-])=O 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C333/02—Monothiocarbamic acids; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/317—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
A találmány tárgya eljárás (I) általános képletű meta- vagy para-szubsztituált a-arilalkánsav-származékok előállítására. A találmányszerinti eljárást úgy végzik, hogy a) a (II) általános képletűvegyületet - ahol a képletben P jelentése egyenes vagy elágazószénláncú 1-6 szénatomos alkilcsoport, fenilcsoport vagy p-nitro-fenil-csoport - egy (III) általános képletű vegyületté alakítják -ahol a képletben Ra és Rb jelentése 1-6 szénatomos alkilcsoport; b) a(III) általános képletű vegyületet a (IIIb) általános képletűvegyületté termikusan átrendezik, c) a (IIIb) általános képletűvegyületet (IIIc) általános képletű vegyületté hidrogénezikkatalitikus úton, d) a (IIIc) képletű vegyületet (I) általános képletűvegyületté alakítják. Ó
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1998MI002332A IT1303685B1 (it) | 1998-10-30 | 1998-10-30 | Procedimento per la preparazione di acidi alfa-arilalcanoici |
| PCT/EP1999/007887 WO2000026176A1 (en) | 1998-10-30 | 1999-10-18 | A process for the preparation of alpha-arylalkanoic acids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HUP0104120A2 true HUP0104120A2 (hu) | 2002-03-28 |
| HUP0104120A3 HUP0104120A3 (en) | 2004-07-28 |
| HU229392B1 HU229392B1 (en) | 2013-11-28 |
Family
ID=11380971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0104120A HU229392B1 (en) | 1998-10-30 | 1999-10-18 | A process for the preparation of alpha-arylalkanoic acids |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6770781B1 (hu) |
| EP (1) | EP1124785B1 (hu) |
| JP (1) | JP4401027B2 (hu) |
| KR (1) | KR100635115B1 (hu) |
| CN (1) | CN1217913C (hu) |
| AT (1) | ATE240933T1 (hu) |
| AU (1) | AU765927B2 (hu) |
| BR (1) | BR9914846A (hu) |
| CA (1) | CA2348412C (hu) |
| CZ (1) | CZ296311B6 (hu) |
| DE (1) | DE69908169T2 (hu) |
| DK (1) | DK1124785T3 (hu) |
| EE (1) | EE04369B1 (hu) |
| ES (1) | ES2199596T3 (hu) |
| HK (1) | HK1043356B (hu) |
| HU (1) | HU229392B1 (hu) |
| IL (2) | IL142833A0 (hu) |
| IT (1) | IT1303685B1 (hu) |
| MX (1) | MXPA01004185A (hu) |
| NO (1) | NO326841B1 (hu) |
| NZ (1) | NZ511369A (hu) |
| PL (1) | PL197732B1 (hu) |
| PT (1) | PT1124785E (hu) |
| RU (1) | RU2252932C2 (hu) |
| SK (1) | SK284949B6 (hu) |
| TR (1) | TR200101165T2 (hu) |
| WO (1) | WO2000026176A1 (hu) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1318466B1 (it) * | 2000-04-14 | 2003-08-25 | Dompe Spa | Ammidi di acidi r-2-(amminoaril)-propionici, utili nella prevenzionedell'attivazione leucocitaria. |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB971700A (en) * | 1961-02-02 | 1964-09-30 | Boots Pure Drug Co Ltd | Anti-Inflammatory Agents |
| HU180811B (en) * | 1976-11-23 | 1983-04-29 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing phenyl-alkyl-carboxylic acids |
| HU182472B (en) | 1978-05-23 | 1984-01-30 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing 2-phenyl-alkancarboxylic acid derivatives |
| US4605758A (en) * | 1981-12-11 | 1986-08-12 | Syntex Pharmaceuticals International Ltd. | Preparation of α-arylalkanoic acids |
| US5061629A (en) * | 1988-01-26 | 1991-10-29 | Hoffman-La Roche Inc. | Production of 2-hydroxy substituted arylalkanoic acids and esters by enzymatic hydrolysis |
| US4910337A (en) * | 1989-01-27 | 1990-03-20 | Mine Safety Appliances Company | Process for the preparation of α-arylalkanoic acids |
| IT1283649B1 (it) | 1996-08-02 | 1998-04-23 | Dompe Spa | Procedimento per la preparazione di acidi 2-aril-propionici e 2-aril-acetici a partire da aril-olefine |
-
1998
- 1998-10-30 IT IT1998MI002332A patent/IT1303685B1/it active
-
1999
- 1999-10-18 TR TR2001/01165T patent/TR200101165T2/xx unknown
- 1999-10-18 EP EP99953873A patent/EP1124785B1/en not_active Expired - Lifetime
- 1999-10-18 SK SK570-2001A patent/SK284949B6/sk not_active IP Right Cessation
- 1999-10-18 CZ CZ20011520A patent/CZ296311B6/cs not_active IP Right Cessation
- 1999-10-18 AU AU10402/00A patent/AU765927B2/en not_active Ceased
- 1999-10-18 CN CN998127442A patent/CN1217913C/zh not_active Expired - Fee Related
- 1999-10-18 PT PT99953873T patent/PT1124785E/pt unknown
- 1999-10-18 EE EEP200100242A patent/EE04369B1/xx not_active IP Right Cessation
- 1999-10-18 RU RU2001114507/04A patent/RU2252932C2/ru not_active IP Right Cessation
- 1999-10-18 IL IL14283399A patent/IL142833A0/xx active IP Right Grant
- 1999-10-18 AT AT99953873T patent/ATE240933T1/de active
- 1999-10-18 US US09/830,449 patent/US6770781B1/en not_active Expired - Fee Related
- 1999-10-18 MX MXPA01004185A patent/MXPA01004185A/es not_active IP Right Cessation
- 1999-10-18 HU HU0104120A patent/HU229392B1/hu not_active IP Right Cessation
- 1999-10-18 BR BR9914846-3A patent/BR9914846A/pt not_active Application Discontinuation
- 1999-10-18 KR KR1020017005305A patent/KR100635115B1/ko not_active IP Right Cessation
- 1999-10-18 JP JP2000579566A patent/JP4401027B2/ja not_active Expired - Fee Related
- 1999-10-18 CA CA002348412A patent/CA2348412C/en not_active Expired - Fee Related
- 1999-10-18 DK DK99953873T patent/DK1124785T3/da active
- 1999-10-18 NZ NZ511369A patent/NZ511369A/xx not_active IP Right Cessation
- 1999-10-18 WO PCT/EP1999/007887 patent/WO2000026176A1/en active IP Right Grant
- 1999-10-18 ES ES99953873T patent/ES2199596T3/es not_active Expired - Lifetime
- 1999-10-18 DE DE69908169T patent/DE69908169T2/de not_active Expired - Lifetime
- 1999-10-18 PL PL347425A patent/PL197732B1/pl not_active IP Right Cessation
-
2001
- 2001-04-27 NO NO20012101A patent/NO326841B1/no not_active IP Right Cessation
- 2001-04-27 IL IL142833A patent/IL142833A/en not_active IP Right Cessation
-
2002
- 2002-03-14 HK HK02101970.0A patent/HK1043356B/zh not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI971312A (fi) | Uudet prostaglandiinisyntaasin estäjät | |
| HUP0303166A2 (hu) | Eljárás 2-(6-helyettesített 1,3-dioxán-4-il)-ecetsav-származékok előállítására | |
| HUP9903836A2 (hu) | Új eljárás Cox-2 inhibítor hatású fenil-szubsztituált 2(5H)-furanonok előállítására | |
| BR0109048A (pt) | Processo para a sìntese de citalopram | |
| ES555954A0 (es) | Procedimiento para la obtencion de esteres de acido sulfurico | |
| HUP0300856A2 (hu) | Eljárás szubsztituált fenil-acetonitrilek elżállítására | |
| HUP0104120A2 (hu) | Eljárás alfa-arilalkánsav-származékok előállítására | |
| DE50107209D1 (de) | Verfahren zur herstellung von 5-aminosalicylsäure | |
| ATE328877T1 (de) | Verfahren zur herstellung von liponsäure und dihydroliponsaüre | |
| DE69823657D1 (de) | Zur herstellung von sulfurierten oligonukleotidanaloga | |
| ES8800215A1 (es) | Un procedimiento enantioselectivo para la preparacion de intermedios para los antibioticos de 1-b-metil-carbapenem | |
| DE60000226T2 (de) | Verfahren zur Herstellung von 5-Carboxyphthalid | |
| ATE225329T1 (de) | Verfahren zur herstellung von r-(-)-carnitin | |
| PT1104397E (pt) | Processo para a preparacao de ester de etilo do acido atropico | |
| DE60014103D1 (de) | Verfahren zur herstellung von debromohymenialdisin und deren analogen | |
| WO2008033335A3 (en) | Process for preparing fluorinated carboxylic acids | |
| RU2001114507A (ru) | Способ получения альфа-арилалканкарбоновых кислот | |
| EP0792936A3 (en) | Process for the preparation of optically active 2-halo-1-(substituted phenyl) ethanol | |
| MXPA03011011A (es) | Procedimiento para la preparacion del derivado del acido 3-aril-2-hidroxipropionico. | |
| MY126799A (en) | Process and intermediates for making 4-cyanosubstituted cyclohexanoic acids. | |
| ATE247632T1 (de) | Verfahren zur herstellung von cyanessigsäureestern | |
| TW368496B (en) | A process for the preparation of 2-aryl-propionic and 2-aryl-acetic acids starting from aryl-olefins | |
| HUP0003438A2 (hu) | Eljárás 5-lipoxigenáz inhibitor hatású pirrol-karboxamid-származékok előállítására | |
| KR960022428A (ko) | 신남산 유도체의 새로운 제조방법 | |
| ATE309185T1 (de) | Verfahren zur herstellung von bisindenylalkanen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB9A | Succession in title |
Owner name: DOMPE' PHA.R.MA S.P.A, IT Free format text: FORMER OWNER(S): DOMPE' S.P.A., IT |
|
| MM4A | Lapse of definitive patent protection due to non-payment of fees |