HUP0103616A3 - Therapeutically active proteins in plants - Google Patents

Therapeutically active proteins in plants

Info

Publication number
HUP0103616A3
HUP0103616A3 HU0103616A HUP0103616A HUP0103616A3 HU P0103616 A3 HUP0103616 A3 HU P0103616A3 HU 0103616 A HU0103616 A HU 0103616A HU P0103616 A HUP0103616 A HU P0103616A HU P0103616 A3 HUP0103616 A3 HU P0103616A3
Authority
HU
Hungary
Prior art keywords
plants
therapeutically active
active proteins
proteins
therapeutically
Prior art date
Application number
HU0103616A
Other languages
English (en)
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of HUP0103616A2 publication Critical patent/HUP0103616A2/hu
Publication of HUP0103616A3 publication Critical patent/HUP0103616A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8214—Plastid transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
HU0103616A 1998-10-07 1999-10-05 Therapeutically active proteins in plants HUP0103616A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16823198A 1998-10-07 1998-10-07
US16736298A 1998-10-07 1998-10-07
PCT/EP1999/007414 WO2000020612A2 (en) 1998-10-07 1999-10-05 Therapeutically active proteins in plants

Publications (2)

Publication Number Publication Date
HUP0103616A2 HUP0103616A2 (hu) 2002-01-28
HUP0103616A3 true HUP0103616A3 (en) 2003-07-28

Family

ID=26863095

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0103616A HUP0103616A3 (en) 1998-10-07 1999-10-05 Therapeutically active proteins in plants

Country Status (14)

Country Link
EP (1) EP1117817A2 (hu)
JP (1) JP2002526116A (hu)
KR (1) KR20010085901A (hu)
CN (1) CN1330718A (hu)
AR (1) AR020717A1 (hu)
AU (2) AU758817B2 (hu)
BR (1) BR9915919A (hu)
CA (1) CA2344269A1 (hu)
HU (1) HUP0103616A3 (hu)
IL (1) IL142041A0 (hu)
PL (1) PL347904A1 (hu)
RU (2) RU2001111881A (hu)
TR (1) TR200101032T2 (hu)
WO (1) WO2000020612A2 (hu)

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IL155588A0 (en) * 2003-04-27 2003-11-23 Metabogal Ltd Methods for expression of enzymatically active recombinant lysosomal enzymes in transgenic plant root cells and vectors used thereby
US7361331B2 (en) * 1996-10-18 2008-04-22 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food Plant bioreactors
AR024934A1 (es) * 1999-07-27 2002-10-30 Novartis Ag Genes quimericos
US7572466B1 (en) 1999-10-13 2009-08-11 Health Research, Inc. Oral immunology using plant product containing a non-enteric pathogen antigen
EP1268832A4 (en) * 2000-02-29 2003-04-02 Univ Auburn PRODUCTION OF ANTIBODIES IN TRANSGENIC PLASTS
AU2001252246A1 (en) * 2000-04-05 2001-10-23 Syngenta Participations Ag Therapeutically active proteins in plants
FR2809413B1 (fr) * 2000-05-29 2004-10-22 Tabacs & Allumettes Ind Production d'allergenes recombinants dans des cellules vegetales
JP2002017186A (ja) * 2000-06-30 2002-01-22 Hayashibara Biochem Lab Inc トランスジェニック植物
GB2364705A (en) * 2000-07-14 2002-02-06 Icgeb Fusion protein expression in plastids
DK1311696T3 (da) 2000-08-11 2012-10-22 Syngenta Participations Ag Fremgangsmåder til stabil transformation af planter
WO2002083072A2 (en) * 2001-04-13 2002-10-24 Boyce Thompson Institute For Plant Research Methods and compositions for stable transgenic plant pharmaceuticals and their use as contraceptives
CA2483337C (en) * 2002-04-23 2015-10-27 The Scripps Research Institute Expression of polypeptides in chloroplasts, and compositions and methods for expressing same
FR2841906B1 (fr) * 2002-07-05 2006-08-18 Stallergenes Sa Molecule d'acide nucleique codant une preproproteine d'allergene d'un acarien du genre dermatophagoides ou euroglyphus et son utilisation pour la production dudit allergene dans les plantes
EP1554387B1 (en) 2002-10-15 2012-01-25 Syngenta Participations AG Plastid transformation
WO2004070016A2 (en) 2003-02-03 2004-08-19 Fraunhofer Usa Inc. System for expression of genes in plants
AU2004213554A1 (en) * 2003-02-18 2004-09-02 Syngenta Participations Ag Expression in plants of antibodies against enterotoxigenic escherichia coli
GB0307989D0 (en) * 2003-04-07 2003-05-14 Mcewen Lab Ltd Therapeutic composition
US7951557B2 (en) 2003-04-27 2011-05-31 Protalix Ltd. Human lysosomal proteins from plant cell culture
WO2005026375A2 (en) 2003-05-22 2005-03-24 Fraunhofer Usa, Inc. Recombinant carrier molecule for expression, delivery and purification of target polypeptides
US8455717B2 (en) 2004-09-29 2013-06-04 Collplant Ltd. Collagen producing plants and methods of generating and using same
AU2012241058B2 (en) * 2005-07-18 2014-04-17 Protalix Ltd. Mucosal or Enteral Administration of Biologically Active Macromolecules
BRPI0616012A2 (pt) * 2005-07-18 2011-05-31 Protalix Ltd administração via mucosa ou intestino de macromoléculas biologicamente ativas
WO2007117264A2 (en) 2005-08-03 2007-10-18 Fraunhofer Usa, Inc. Compositions and methods for production of immunoglobulins
US8124103B2 (en) 2006-02-13 2012-02-28 Fraunhofer Usa, Inc Influenza antigens, vaccine compositions, and related methods
GB0604938D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Proteins, nucleic acids and medicaments
GB0604966D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Medicaments and proteins
GB0604964D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Protein folding
GB0617816D0 (en) * 2006-09-11 2006-10-18 Renovo Ltd Nucleic acids and methods of protein expression
JP2010525833A (ja) 2007-05-07 2010-07-29 プロタリクス リミテッド 大規模な使い捨て型バイオリアクター
GB2449466B (en) * 2007-05-23 2009-11-18 Algentech Ltd Production of proteins in plant tissue
CA2692933C (en) 2007-07-11 2016-10-18 Fraunhofer Usa, Inc. Yersinia pestis antigens, vaccine compositions, and related methods
CN101951951A (zh) * 2007-10-31 2011-01-19 中佛罗里达大学研究基金有限公司 叶绿体衍生的人类疟疾疫苗抗原
SG193139A1 (en) * 2008-06-30 2013-09-30 Orf Liftaekni Hf Use of plant-derived recombinant growth factors in skin care
US8734803B2 (en) 2008-09-28 2014-05-27 Ibio Inc. Humanized neuraminidase antibody and methods of use thereof
US9175300B2 (en) 2008-11-27 2015-11-03 Vanga Siva Reddy Method of expressing foreign protein in plastids
US9551005B2 (en) * 2009-07-16 2017-01-24 Kenneth John Piller Immunoassay for detecting thyroglobulin utilizing soybean produced recombinant thyroglobulin
WO2011041391A1 (en) 2009-09-29 2011-04-07 Fraunhofer Usa, Inc. Influenza hemagglutinin antibodies, compositions, and related methods
NZ600007A (en) * 2009-11-18 2014-08-29 Agriculture Victoria Serv Pty Angiogenin expression in plants
WO2012170678A1 (en) 2011-06-07 2012-12-13 Fraunhofer Usa, Inc. In vivo de-glycosylation of recombinant proteins by co-expression with pngase f
JP2013040138A (ja) * 2011-08-17 2013-02-28 Univ Of Tsukuba 活性化型リコンビナント花粉アレルゲンの作製方法
CA2882977C (en) 2012-08-23 2019-05-21 Transalgae Israel Ltd. Transgenic microalgae and use thereof for oral delivery of proteins
WO2015121863A1 (en) 2014-02-12 2015-08-20 Transalgae Israel Ltd. Algal based edible vaccines
AU2015261440A1 (en) 2014-05-14 2017-01-05 Barbara BURWINKEL Synthesis of double-stranded nucleic acids
FR3021328B1 (fr) * 2014-05-23 2018-01-05 Angany Inc. Production commerciale de l'allergene amb a1 par expression transitoire chez les plantes
CN104561353B (zh) * 2015-01-29 2017-01-11 中国农业科学院蔬菜花卉研究所 与甘蓝育性紧密连锁的InDel标记及其检测方法和应用
EP3432902A4 (en) * 2016-03-20 2019-08-28 The Trustees of The University of Pennsylvania CODON OPTIMIZATION AND RIBOSOMIC PROFILING TO ENHANCE TRANSGENIC EXPRESSION IN UPPER PLANT CHLOROPLASTS

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US5451513A (en) * 1990-05-01 1995-09-19 The State University of New Jersey Rutgers Method for stably transforming plastids of multicellular plants
GB9319429D0 (en) * 1993-09-21 1993-11-03 London Health Ass Methods and products for controlling immune responses in mammals
US5576198A (en) * 1993-12-14 1996-11-19 Calgene, Inc. Controlled expression of transgenic constructs in plant plastids
FR2736930B1 (fr) * 1995-07-17 1997-09-19 Biocem Procede de production, par des cellules vegetales, de proteines heminiques, proteines ainsi obtenues et produits contenant ces proteines
ZA965786B (en) * 1995-07-19 1997-01-27 Kimberly Clark Co Nonwoven barrier and method of making the same
WO1997004123A1 (en) * 1995-07-19 1997-02-06 Gel Tech Group Inc. Collagen compound production in plants
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JP2000506019A (ja) * 1996-03-06 2000-05-23 ラトガーズ・ユニバーシティ アラビドプシス・サリアナアにおけるプラスチド形質転換
BR9713462A (pt) * 1996-08-09 2000-03-28 Calgene Inc Métodos para produção de compostos carotenóides e óleos especiais em sementes de plantas.
WO1998006861A2 (en) * 1996-08-15 1998-02-19 Agrivax Incorporated Delivery of tolerogenic antigens via edible plants or plant-derived products
ES2242234T3 (es) * 1996-09-12 2005-11-01 Syngenta Participations Ag Plantas transgenicas que expresan enzimas celuloliticas.
EP1007706B1 (en) * 1997-01-17 2012-10-10 The Scripps Research Institute Rna binding protein and binding site useful for expression of recombinant molecules
DE69830317T3 (de) * 1997-08-07 2009-03-19 Auburn University, Auburn Universelle integrations- und expressionsvektoren für chloroplasten, transformierte pflanzen und produkte hiervon
ES2286886T3 (es) * 1998-07-10 2007-12-01 Calgene Llc Expresion de peptidos eucarioticos en plastidos de plantas.

Also Published As

Publication number Publication date
AU2003200126A1 (en) 2003-04-17
RU2003131696A (ru) 2005-04-20
PL347904A1 (en) 2002-04-22
AR020717A1 (es) 2002-05-22
CN1330718A (zh) 2002-01-09
BR9915919A (pt) 2001-08-21
IL142041A0 (en) 2002-03-10
AU6334099A (en) 2000-04-26
HUP0103616A2 (hu) 2002-01-28
WO2000020612A2 (en) 2000-04-13
WO2000020612A3 (en) 2000-07-06
TR200101032T2 (tr) 2001-10-22
CA2344269A1 (en) 2000-04-13
JP2002526116A (ja) 2002-08-20
AU2003200126A9 (en) 2003-04-17
KR20010085901A (ko) 2001-09-07
EP1117817A2 (en) 2001-07-25
AU758817B2 (en) 2003-04-03
RU2001111881A (ru) 2003-06-20

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