HUP0103616A2 - Gyógyászatilag hatásos fehérjék növényekben - Google Patents

Gyógyászatilag hatásos fehérjék növényekben

Info

Publication number
HUP0103616A2
HUP0103616A2 HU0103616A HUP0103616A HUP0103616A2 HU P0103616 A2 HUP0103616 A2 HU P0103616A2 HU 0103616 A HU0103616 A HU 0103616A HU P0103616 A HUP0103616 A HU P0103616A HU P0103616 A2 HUP0103616 A2 HU P0103616A2
Authority
HU
Hungary
Prior art keywords
plants
therapeutically active
active proteins
medicinally effective
effective proteins
Prior art date
Application number
HU0103616A
Other languages
English (en)
Inventor
Stephen Arthur Goff
Monika Else Griot-Wenk
Peter Bernard Heifetz
Annmarie Bloom Tuttle
Original Assignee
Syngenta Participations Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag. filed Critical Syngenta Participations Ag.
Publication of HUP0103616A2 publication Critical patent/HUP0103616A2/hu
Publication of HUP0103616A3 publication Critical patent/HUP0103616A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8214—Plastid transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Environmental Sciences (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Physiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Ophthalmology & Optometry (AREA)

Abstract

A találmány gyógyászatilag hatásos fehérjéket kifejező növényekrevonatkozik. Pontosabban a találmány tárgyát a gyógyászatilag hatásosfehérjéket a sejtszervecskékben, előnyösen a vakuólumokban vagyelőnyösebben a növényi plasztiszokban kifejező növények képezik.Atranszgénikus növények betegségek kezelésére vagy megelőzésérealkalmazhatók. Az egyik előnyös megvalósítási módban a transzgénikusnövényeket vagy az ezekből származó növényi anyagot tartalmazókészítmény orálisan adható be. Ó
HU0103616A 1998-10-07 1999-10-05 Therapeutically active proteins in plants HUP0103616A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16823198A 1998-10-07 1998-10-07
US16736298A 1998-10-07 1998-10-07
PCT/EP1999/007414 WO2000020612A2 (en) 1998-10-07 1999-10-05 Therapeutically active proteins in plants

Publications (2)

Publication Number Publication Date
HUP0103616A2 true HUP0103616A2 (hu) 2002-01-28
HUP0103616A3 HUP0103616A3 (en) 2003-07-28

Family

ID=26863095

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0103616A HUP0103616A3 (en) 1998-10-07 1999-10-05 Therapeutically active proteins in plants

Country Status (14)

Country Link
EP (1) EP1117817A2 (hu)
JP (1) JP2002526116A (hu)
KR (1) KR20010085901A (hu)
CN (1) CN1330718A (hu)
AR (1) AR020717A1 (hu)
AU (2) AU758817B2 (hu)
BR (1) BR9915919A (hu)
CA (1) CA2344269A1 (hu)
HU (1) HUP0103616A3 (hu)
IL (1) IL142041A0 (hu)
PL (1) PL347904A1 (hu)
RU (2) RU2001111881A (hu)
TR (1) TR200101032T2 (hu)
WO (1) WO2000020612A2 (hu)

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WO2001077353A2 (en) * 2000-04-05 2001-10-18 Syngenta Participations Ag Expression of pollen allergens in plastids
FR2809413B1 (fr) * 2000-05-29 2004-10-22 Tabacs & Allumettes Ind Production d'allergenes recombinants dans des cellules vegetales
JP2002017186A (ja) * 2000-06-30 2002-01-22 Hayashibara Biochem Lab Inc トランスジェニック植物
GB2364705A (en) * 2000-07-14 2002-02-06 Icgeb Fusion protein expression in plastids
BR0113156A (pt) 2000-08-11 2003-07-08 Syngenta Participations Ag Método para produzir um planta dicotiledÈnea transformada, célula de planta transformada, cultura de múltiplos brotos, planta transformada, semente produzida pela planta transformada, método para produzir uma planta compreendendo um genoma de plastìdeo transformado, genoma de plastìdeo transformado, e, plastìdeo
BR0208880A (pt) * 2001-04-13 2004-12-07 Thompson Boyce Plant Res Métodos para produzir um homogeneizado seco estável de uma planta transgênica que expressa uma proteìna heteróloga, para prevenir uma doença patogênica em um animal, para liberar uma proteìna transgênica a um animal, de contracepção e para induzir uma resposta imune mucosal, homogeneizado seco estável, composição farmacêutica, planta transgênica, célula de planta, vetor plasmìdico para transformar uma célula de planta, composição de alimento, e, alimento
CN1886512B (zh) * 2002-04-23 2015-11-25 斯克里普斯研究所 多肽在叶绿体中的表达以及用于表达多肽的组合物和方法
WO2007095318A2 (en) 2006-02-13 2007-08-23 Fraunhofer Usa, Inc. Influenza antigens, vaccine compositions, and related methods
FR2841906B1 (fr) * 2002-07-05 2006-08-18 Stallergenes Sa Molecule d'acide nucleique codant une preproproteine d'allergene d'un acarien du genre dermatophagoides ou euroglyphus et son utilisation pour la production dudit allergene dans les plantes
DK1554387T3 (da) 2002-10-15 2012-05-14 Syngenta Participations Ag Plastidtransformation
US7491509B2 (en) 2003-02-03 2009-02-17 Fraunhofer Usa, Inc. System for expression of genes in plants
WO2004074491A2 (en) * 2003-02-18 2004-09-02 Syngeta Participations Ag Expression in plants of antibodies against enterotoxigenic escherichia coli
GB0307989D0 (en) * 2003-04-07 2003-05-14 Mcewen Lab Ltd Therapeutic composition
US7951557B2 (en) 2003-04-27 2011-05-31 Protalix Ltd. Human lysosomal proteins from plant cell culture
EP1664322B1 (en) 2003-05-22 2013-07-10 Fraunhofer USA, Inc. Recombinant carrier molecule for expression, delivery and purification of target polypeptides
US8455717B2 (en) 2004-09-29 2013-06-04 Collplant Ltd. Collagen producing plants and methods of generating and using same
US20110070201A1 (en) * 2005-07-18 2011-03-24 Protalix Ltd. Mucosal or enteral administration of biologically active macromolecules
AU2012241058B2 (en) * 2005-07-18 2014-04-17 Protalix Ltd. Mucosal or Enteral Administration of Biologically Active Macromolecules
US8962278B2 (en) 2005-08-03 2015-02-24 Ibio Inc. Compositions and methods for production of immunoglobulins
GB0604964D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Protein folding
GB0604938D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Proteins, nucleic acids and medicaments
GB0604966D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Medicaments and proteins
GB0617816D0 (en) * 2006-09-11 2006-10-18 Renovo Ltd Nucleic acids and methods of protein expression
EP2150608B1 (en) 2007-05-07 2017-11-29 Protalix Ltd. Large scale disposable bioreactor
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US8404252B2 (en) 2007-07-11 2013-03-26 Fraunhofer Usa, Inc. Yersinia pestis antigens, vaccine compositions, and related methods
WO2009058355A2 (en) * 2007-10-31 2009-05-07 University Of Central Florida Research Foundation, Inc. Chloroplast-derived human vaccine antigens against malaria
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US9551005B2 (en) * 2009-07-16 2017-01-24 Kenneth John Piller Immunoassay for detecting thyroglobulin utilizing soybean produced recombinant thyroglobulin
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CA2780989C (en) * 2009-11-18 2020-08-18 Agriculture Victoria Services Pty Ltd Angiogenin expression in plants
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Also Published As

Publication number Publication date
KR20010085901A (ko) 2001-09-07
AU758817B2 (en) 2003-04-03
HUP0103616A3 (en) 2003-07-28
IL142041A0 (en) 2002-03-10
AU2003200126A1 (en) 2003-04-17
CN1330718A (zh) 2002-01-09
JP2002526116A (ja) 2002-08-20
RU2003131696A (ru) 2005-04-20
EP1117817A2 (en) 2001-07-25
PL347904A1 (en) 2002-04-22
AR020717A1 (es) 2002-05-22
CA2344269A1 (en) 2000-04-13
WO2000020612A2 (en) 2000-04-13
BR9915919A (pt) 2001-08-21
WO2000020612A3 (en) 2000-07-06
RU2001111881A (ru) 2003-06-20
TR200101032T2 (tr) 2001-10-22
AU6334099A (en) 2000-04-26
AU2003200126A9 (en) 2003-04-17

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