TR200101032T2 - Bitkilerdeki sağaltıcı yönden aktif proteinler. - Google Patents

Bitkilerdeki sağaltıcı yönden aktif proteinler.

Info

Publication number
TR200101032T2
TR200101032T2 TR2001/01032T TR200101032T TR200101032T2 TR 200101032 T2 TR200101032 T2 TR 200101032T2 TR 2001/01032 T TR2001/01032 T TR 2001/01032T TR 200101032 T TR200101032 T TR 200101032T TR 200101032 T2 TR200101032 T2 TR 200101032T2
Authority
TR
Turkey
Prior art keywords
plants
active proteins
host
healing active
present
Prior art date
Application number
TR2001/01032T
Other languages
English (en)
Turkish (tr)
Inventor
Bernard Heifetz Peter
Arthur Goff Stephen
Bloom Tuttle Annmarie
Else Griot-Wenk Monika
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of TR200101032T2 publication Critical patent/TR200101032T2/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8214—Plastid transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Environmental Sciences (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pain & Pain Management (AREA)
TR2001/01032T 1998-10-07 1999-10-05 Bitkilerdeki sağaltıcı yönden aktif proteinler. TR200101032T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16823198A 1998-10-07 1998-10-07
US16736298A 1998-10-07 1998-10-07

Publications (1)

Publication Number Publication Date
TR200101032T2 true TR200101032T2 (tr) 2001-10-22

Family

ID=26863095

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/01032T TR200101032T2 (tr) 1998-10-07 1999-10-05 Bitkilerdeki sağaltıcı yönden aktif proteinler.

Country Status (14)

Country Link
EP (1) EP1117817A2 (xx)
JP (1) JP2002526116A (xx)
KR (1) KR20010085901A (xx)
CN (1) CN1330718A (xx)
AR (1) AR020717A1 (xx)
AU (2) AU758817B2 (xx)
BR (1) BR9915919A (xx)
CA (1) CA2344269A1 (xx)
HU (1) HUP0103616A3 (xx)
IL (1) IL142041A0 (xx)
PL (1) PL347904A1 (xx)
RU (2) RU2001111881A (xx)
TR (1) TR200101032T2 (xx)
WO (1) WO2000020612A2 (xx)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050032211A1 (en) * 1996-09-26 2005-02-10 Metabogal Ltd. Cell/tissue culturing device, system and method
IL155588A0 (en) * 2003-04-27 2003-11-23 Metabogal Ltd Methods for expression of enzymatically active recombinant lysosomal enzymes in transgenic plant root cells and vectors used thereby
US7361331B2 (en) * 1996-10-18 2008-04-22 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food Plant bioreactors
WO2001007590A2 (en) * 1999-07-27 2001-02-01 Syngenta Participations Ag Chimeric genes for plastid expression
US7572466B1 (en) 1999-10-13 2009-08-11 Health Research, Inc. Oral immunology using plant product containing a non-enteric pathogen antigen
CA2401965A1 (en) * 2000-02-29 2001-09-07 Auburn University Production of antibodies in transgenic plastids
WO2001077353A2 (en) * 2000-04-05 2001-10-18 Syngenta Participations Ag Expression of pollen allergens in plastids
FR2809413B1 (fr) * 2000-05-29 2004-10-22 Tabacs & Allumettes Ind Production d'allergenes recombinants dans des cellules vegetales
JP2002017186A (ja) * 2000-06-30 2002-01-22 Hayashibara Biochem Lab Inc トランスジェニック植物
GB2364705A (en) * 2000-07-14 2002-02-06 Icgeb Fusion protein expression in plastids
EP1311696B1 (en) 2000-08-11 2012-07-25 Syngenta Participations AG Methods for stable transformation of plants
JP4500493B2 (ja) * 2001-04-13 2010-07-14 ボイス トンプソン インステイテュート フォア プラント リサーチ 安定なトランスジェニック植物医薬品の作製方法および組成物ならびに避妊薬としてのその使用
MXPA04010432A (es) * 2002-04-23 2005-05-27 Scripps Research Inst Expresion de polipeptidos en cloroplastos, y composiciones y metodos para expresar los mismos.
FR2841906B1 (fr) * 2002-07-05 2006-08-18 Stallergenes Sa Molecule d'acide nucleique codant une preproproteine d'allergene d'un acarien du genre dermatophagoides ou euroglyphus et son utilisation pour la production dudit allergene dans les plantes
SI1554387T1 (sl) 2002-10-15 2012-05-31 Syngenta Participations Ag Transformacija plastida
ES2531125T3 (es) 2003-02-03 2015-03-10 Ibio Inc Sistema para la expresión de genes en plantas
EP1597372A2 (en) * 2003-02-18 2005-11-23 Syngeta Participations AG Expression in plants of antibodies against enterotoxigenic escherichia coli
GB0307989D0 (en) * 2003-04-07 2003-05-14 Mcewen Lab Ltd Therapeutic composition
US7951557B2 (en) 2003-04-27 2011-05-31 Protalix Ltd. Human lysosomal proteins from plant cell culture
WO2005026375A2 (en) 2003-05-22 2005-03-24 Fraunhofer Usa, Inc. Recombinant carrier molecule for expression, delivery and purification of target polypeptides
US8455717B2 (en) 2004-09-29 2013-06-04 Collplant Ltd. Collagen producing plants and methods of generating and using same
AU2012241058B2 (en) * 2005-07-18 2014-04-17 Protalix Ltd. Mucosal or Enteral Administration of Biologically Active Macromolecules
BRPI0616012A2 (pt) * 2005-07-18 2011-05-31 Protalix Ltd administração via mucosa ou intestino de macromoléculas biologicamente ativas
KR101446025B1 (ko) 2005-08-03 2014-10-01 아이바이오, 인크. 면역글로불린의 생산을 위한 조성물 및 방법
BRPI0707733B1 (pt) 2006-02-13 2019-12-31 Fraunhofer Usa Inc antígeno isolado, composição de vacina, uso da referida composição e método para produção de uma proteína de antígeno
GB0604966D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Medicaments and proteins
GB0604938D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Proteins, nucleic acids and medicaments
GB0604964D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Protein folding
GB0617816D0 (en) * 2006-09-11 2006-10-18 Renovo Ltd Nucleic acids and methods of protein expression
DK2150608T3 (en) 2007-05-07 2018-03-12 Protalix Ltd LARGE-SCALE ENTRY BIOR ACTOR
GB2449466B (en) * 2007-05-23 2009-11-18 Algentech Ltd Production of proteins in plant tissue
CA2692933C (en) 2007-07-11 2016-10-18 Fraunhofer Usa, Inc. Yersinia pestis antigens, vaccine compositions, and related methods
BRPI0818268A2 (pt) * 2007-10-31 2017-05-09 Univ Central Florida Res Found Inc antígenos de vacina humana derivados de cloroplasto contra a malária
BRPI0913983A2 (pt) * 2008-06-30 2015-10-20 Orf Liftaekni Hf composição cosmética e/ou terapêutica, e, método para fabricar um produto para cuidado da pele tópico
US8734803B2 (en) 2008-09-28 2014-05-27 Ibio Inc. Humanized neuraminidase antibody and methods of use thereof
US9175300B2 (en) 2008-11-27 2015-11-03 Vanga Siva Reddy Method of expressing foreign protein in plastids
US9551005B2 (en) * 2009-07-16 2017-01-24 Kenneth John Piller Immunoassay for detecting thyroglobulin utilizing soybean produced recombinant thyroglobulin
CA2776144C (en) 2009-09-29 2020-10-27 Fraunhofer Usa, Inc. Influenza hemagglutinin antibodies, compositions, and related methods
WO2011060490A1 (en) * 2009-11-18 2011-05-26 Agriculture Victoria Services Pty Ltd Angiogenin expression in plants
US11673926B2 (en) 2011-06-07 2023-06-13 Ibio, Inc. In vivo de-glycosylation of recombinant proteins by co-expression with PNGase F
JP2013040138A (ja) * 2011-08-17 2013-02-28 Univ Of Tsukuba 活性化型リコンビナント花粉アレルゲンの作製方法
CN108929855A (zh) * 2012-08-23 2018-12-04 特郎萨格以色列有限公司 转基因微藻和其用于口服递送蛋白质的用途
JP6578283B2 (ja) 2014-02-12 2019-09-18 トランサルガエ イスラエル リミテッド 藻類をベースとした食用ワクチン
EA035092B1 (ru) * 2014-05-14 2020-04-27 Барбара Бурвинкель Синтез двухцепочечных нуклеиновых кислот
FR3021328B1 (fr) * 2014-05-23 2018-01-05 Angany Inc. Production commerciale de l'allergene amb a1 par expression transitoire chez les plantes
CN104561353B (zh) * 2015-01-29 2017-01-11 中国农业科学院蔬菜花卉研究所 与甘蓝育性紧密连锁的InDel标记及其检测方法和应用
EP3432902A4 (en) * 2016-03-20 2019-08-28 The Trustees of The University of Pennsylvania CODON OPTIMIZATION AND RIBOSOMIC PROFILING TO ENHANCE TRANSGENIC EXPRESSION IN UPPER PLANT CHLOROPLASTS

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5451513A (en) * 1990-05-01 1995-09-19 The State University of New Jersey Rutgers Method for stably transforming plastids of multicellular plants
GB9319429D0 (en) * 1993-09-21 1993-11-03 London Health Ass Methods and products for controlling immune responses in mammals
US5576198A (en) * 1993-12-14 1996-11-19 Calgene, Inc. Controlled expression of transgenic constructs in plant plastids
FR2736930B1 (fr) * 1995-07-17 1997-09-19 Biocem Procede de production, par des cellules vegetales, de proteines heminiques, proteines ainsi obtenues et produits contenant ces proteines
WO1997004123A1 (en) * 1995-07-19 1997-02-06 Gel Tech Group Inc. Collagen compound production in plants
ZA965786B (en) * 1995-07-19 1997-01-27 Kimberly Clark Co Nonwoven barrier and method of making the same
RU2192466C2 (ru) * 1995-08-10 2002-11-10 Ратгерс Юниверсити Кодируемая ядерной днк система транскрипции в пластидах высших растений
US6376744B1 (en) * 1996-03-06 2002-04-23 Rutgers, The State University Of New Jersey Plastid transformation in Arabidopsis thaliana
CN1227609A (zh) * 1996-08-09 1999-09-01 卡尔金公司 在植物种子中生产类胡萝卜素化合物和特产油类的方法
CA2263730A1 (en) * 1996-08-15 1998-02-19 Agrivax Incorporated Delivery of tolerogenic antigens via edible plants or plant-derived products
ES2242234T3 (es) * 1996-09-12 2005-11-01 Syngenta Participations Ag Plantas transgenicas que expresan enzimas celuloliticas.
USRE44266E1 (en) * 1997-01-17 2013-06-04 The Scripps Research Institute Expression of eukaryotic polypeptides in chloroplasts
JP2002524023A (ja) * 1997-08-07 2002-08-06 オーバーン・ユニバーシティ 万能葉緑体組込および発現ベクター、その形質転換植物ならびに生産物
DE69935857T2 (de) * 1998-07-10 2008-01-10 Calgene Llc, Davis Expression eukarotischer peptide in pflanzenplastiden

Also Published As

Publication number Publication date
AU6334099A (en) 2000-04-26
AU758817B2 (en) 2003-04-03
JP2002526116A (ja) 2002-08-20
AR020717A1 (es) 2002-05-22
CN1330718A (zh) 2002-01-09
EP1117817A2 (en) 2001-07-25
BR9915919A (pt) 2001-08-21
RU2003131696A (ru) 2005-04-20
HUP0103616A2 (hu) 2002-01-28
AU2003200126A9 (en) 2003-04-17
RU2001111881A (ru) 2003-06-20
AU2003200126A1 (en) 2003-04-17
WO2000020612A3 (en) 2000-07-06
KR20010085901A (ko) 2001-09-07
WO2000020612A2 (en) 2000-04-13
PL347904A1 (en) 2002-04-22
IL142041A0 (en) 2002-03-10
HUP0103616A3 (en) 2003-07-28
CA2344269A1 (en) 2000-04-13

Similar Documents

Publication Publication Date Title
TR200101032T2 (tr) Bitkilerdeki sağaltıcı yönden aktif proteinler.
BR9914360A (pt) N-aralquilaminotetralinas como ligandos para oreceptor neuropeptìdeo yy5
MXPA03002218A (es) Peptidos antimicrobianos y metodos de uso.
EE9800080A (et) (Metüülsulfonüül)fenüül-2-(5H)-furanoonid, nende kasutamine ja farmatseutilised kompositsioonid
ATE361084T1 (de) Topische pharmazeutische zusammensetzungen mit proanthocyanidinen, glycyrrhetinic säure und telmesteine zur behandlung von dermatitis
CY1115082T1 (el) Υποκατεστημενα παραγωγα 1,3-διφαινυλπροπανιου, παρασκευες και χρησεις αυτων
NO962791L (no) Preparater inneholdende nukleinsyrer, deres fremstilling og anvendelse
IS6194A (is) Serínprótínasar úr fiski og notkun þeirra í lyf og snyrtivörur
SE9800836D0 (sv) New Compounds
EA200401471A1 (ru) Применение ингибиторов сетр и возможных ингибиторов hmg coa и/или антигипертензивных агентов
DE60143292D1 (de) Varianten des menschlichen Koagulationsfaktors VII
PT1246809E (pt) Compostos de 5-aril-1h-1,2,4-triazole como inibidores de ciclooxigenase-2 e composicoes farmaceuticas que os contem
DZ3165A1 (fr) Composition alimentaire ou pharmaceutique utiliseepour prevenir ou traiter l'hyperoxalurie.
DK0994710T4 (da) Farmaceutiske præparater til oral indgivelse omfattende en benzylhydrylpiperazin og en cyclodextrin
IL171914A0 (en) Variants of il-18bp, their preparation and pharmaceutical compositions containing them
DE60111362D1 (de) Stabilisierte ascorbinsäure-lösungen
DE60141636D1 (de) Phospholipidderivate von valproinsäure und ihre kombinationen
EA200600403A1 (ru) Препараты кладрибина для улучшенной пероральной доставки и доставки через слизистые оболочки
DE60142519D1 (de) Dna-expressionsvektoren
TR200100637T2 (tr) Yeni doğal ürün türevleri
NO20030802D0 (no) Aminoalkoksybenzoyl-benzofuran- eller benzotiofenderivater, fremgangsmåte for deres fremstilling og preparater inneholdende de samme
DE59809283D1 (de) Inhibitoren für den urokinaserezeptor
WO2004006830A3 (en) Use of ccn protein family members for the treatment of disorder associated to an altered calcium and/or sodium flux
ATE555787T1 (de) Behandlungseffekte von überschüssigen reaktiven sauerstoffspezies
BR0113674A (pt) Peptìdeos antiangiogênicos