AR020717A1 - Proteinas terapeuticamente activas en plantas. - Google Patents
Proteinas terapeuticamente activas en plantas.Info
- Publication number
- AR020717A1 AR020717A1 ARP990105036A ARP990105036A AR020717A1 AR 020717 A1 AR020717 A1 AR 020717A1 AR P990105036 A ARP990105036 A AR P990105036A AR P990105036 A ARP990105036 A AR P990105036A AR 020717 A1 AR020717 A1 AR 020717A1
- Authority
- AR
- Argentina
- Prior art keywords
- plants
- therapeutically active
- active proteins
- host
- transgenic plants
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 230000009261 transgenic effect Effects 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 210000002706 plastid Anatomy 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000009466 transformation Effects 0.000 abstract 1
- 210000003934 vacuole Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8214—Plastid transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Environmental Sciences (AREA)
- Transplantation (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Ophthalmology & Optometry (AREA)
- Physiology (AREA)
- Developmental Biology & Embryology (AREA)
- Pain & Pain Management (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16736298A | 1998-10-07 | 1998-10-07 | |
US16823198A | 1998-10-07 | 1998-10-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR020717A1 true AR020717A1 (es) | 2002-05-22 |
Family
ID=26863095
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP990105036A AR020717A1 (es) | 1998-10-07 | 1999-10-05 | Proteinas terapeuticamente activas en plantas. |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1117817A2 (hu) |
JP (1) | JP2002526116A (hu) |
KR (1) | KR20010085901A (hu) |
CN (1) | CN1330718A (hu) |
AR (1) | AR020717A1 (hu) |
AU (2) | AU758817B2 (hu) |
BR (1) | BR9915919A (hu) |
CA (1) | CA2344269A1 (hu) |
HU (1) | HUP0103616A3 (hu) |
IL (1) | IL142041A0 (hu) |
PL (1) | PL347904A1 (hu) |
RU (2) | RU2001111881A (hu) |
TR (1) | TR200101032T2 (hu) |
WO (1) | WO2000020612A2 (hu) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL155588A0 (en) * | 2003-04-27 | 2003-11-23 | Metabogal Ltd | Methods for expression of enzymatically active recombinant lysosomal enzymes in transgenic plant root cells and vectors used thereby |
US20050032211A1 (en) * | 1996-09-26 | 2005-02-10 | Metabogal Ltd. | Cell/tissue culturing device, system and method |
US7361331B2 (en) * | 1996-10-18 | 2008-04-22 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food | Plant bioreactors |
AU6277600A (en) * | 1999-07-27 | 2001-02-13 | Syngenta Participations Ag | Novel chimeric genes |
US7572466B1 (en) | 1999-10-13 | 2009-08-11 | Health Research, Inc. | Oral immunology using plant product containing a non-enteric pathogen antigen |
EP1268832A4 (en) * | 2000-02-29 | 2003-04-02 | Univ Auburn | PRODUCTION OF ANTIBODIES IN TRANSGENIC PLASTS |
AU2001252246A1 (en) * | 2000-04-05 | 2001-10-23 | Syngenta Participations Ag | Therapeutically active proteins in plants |
FR2809413B1 (fr) * | 2000-05-29 | 2004-10-22 | Tabacs & Allumettes Ind | Production d'allergenes recombinants dans des cellules vegetales |
JP2002017186A (ja) * | 2000-06-30 | 2002-01-22 | Hayashibara Biochem Lab Inc | トランスジェニック植物 |
GB2364705A (en) * | 2000-07-14 | 2002-02-06 | Icgeb | Fusion protein expression in plastids |
AU8980001A (en) | 2000-08-11 | 2002-02-25 | Syngenta Participations Ag | Methods for stable transformation of plants |
CA2441699A1 (en) * | 2001-04-13 | 2002-10-24 | Boyce Thompson Institute For Plant Research | Methods and compositions for stable transgenic plant pharmaceuticals and their use as contraceptives |
CN1886512B (zh) * | 2002-04-23 | 2015-11-25 | 斯克里普斯研究所 | 多肽在叶绿体中的表达以及用于表达多肽的组合物和方法 |
FR2841906B1 (fr) * | 2002-07-05 | 2006-08-18 | Stallergenes Sa | Molecule d'acide nucleique codant une preproproteine d'allergene d'un acarien du genre dermatophagoides ou euroglyphus et son utilisation pour la production dudit allergene dans les plantes |
ATE542908T1 (de) | 2002-10-15 | 2012-02-15 | Syngenta Participations Ag | Plastidtransformation |
EP1594956A4 (en) | 2003-02-03 | 2007-08-01 | Fraunhofer Usa Inc | SYSTEM FOR EXPRESSION OF GENES IN PLANTS |
WO2004074491A2 (en) * | 2003-02-18 | 2004-09-02 | Syngeta Participations Ag | Expression in plants of antibodies against enterotoxigenic escherichia coli |
GB0307989D0 (en) * | 2003-04-07 | 2003-05-14 | Mcewen Lab Ltd | Therapeutic composition |
US7951557B2 (en) | 2003-04-27 | 2011-05-31 | Protalix Ltd. | Human lysosomal proteins from plant cell culture |
CA2526720C (en) | 2003-05-22 | 2013-10-22 | Fraunhofer Usa, Inc. | Recombinant carrier molecule for expression, delivery and purification of target polypeptides |
US8455717B2 (en) | 2004-09-29 | 2013-06-04 | Collplant Ltd. | Collagen producing plants and methods of generating and using same |
EP2484768A3 (en) * | 2005-07-18 | 2012-11-21 | Protalix Ltd. | Mucosal or enteral administration of biologically active macromolecules |
AU2012241058B2 (en) * | 2005-07-18 | 2014-04-17 | Protalix Ltd. | Mucosal or Enteral Administration of Biologically Active Macromolecules |
EP1919504B1 (en) | 2005-08-03 | 2013-10-16 | iBio, Inc. | Antibody to bacillus anthracis protective antigen |
JP2009526526A (ja) | 2006-02-13 | 2009-07-23 | フラウンホーファー ユーエスエー, インコーポレイテッド | インフルエンザ抗原、ワクチン組成物、および関連する方法 |
GB0604966D0 (en) | 2006-03-11 | 2006-04-19 | Renovo Ltd | Medicaments and proteins |
GB0604938D0 (en) | 2006-03-11 | 2006-04-19 | Renovo Ltd | Proteins, nucleic acids and medicaments |
GB0604964D0 (en) | 2006-03-11 | 2006-04-19 | Renovo Ltd | Protein folding |
GB0617816D0 (en) * | 2006-09-11 | 2006-10-18 | Renovo Ltd | Nucleic acids and methods of protein expression |
SI2150608T1 (en) | 2007-05-07 | 2018-04-30 | Protalix Ltd. | An extensive disposable bioreactor |
GB2449466B (en) * | 2007-05-23 | 2009-11-18 | Algentech Ltd | Production of proteins in plant tissue |
CA2692933C (en) | 2007-07-11 | 2016-10-18 | Fraunhofer Usa, Inc. | Yersinia pestis antigens, vaccine compositions, and related methods |
CN101951951A (zh) * | 2007-10-31 | 2011-01-19 | 中佛罗里达大学研究基金有限公司 | 叶绿体衍生的人类疟疾疫苗抗原 |
MX2011000047A (es) * | 2008-06-30 | 2011-06-16 | Orf Liftaekni Hf | Uso de factores de crecimiento recombinantes derivados de plantas en el cuidado de la piel. |
US8734803B2 (en) | 2008-09-28 | 2014-05-27 | Ibio Inc. | Humanized neuraminidase antibody and methods of use thereof |
US9175300B2 (en) | 2008-11-27 | 2015-11-03 | Vanga Siva Reddy | Method of expressing foreign protein in plastids |
US9551005B2 (en) * | 2009-07-16 | 2017-01-24 | Kenneth John Piller | Immunoassay for detecting thyroglobulin utilizing soybean produced recombinant thyroglobulin |
WO2011041391A1 (en) | 2009-09-29 | 2011-04-07 | Fraunhofer Usa, Inc. | Influenza hemagglutinin antibodies, compositions, and related methods |
US20120309092A1 (en) * | 2009-11-18 | 2012-12-06 | Agriculture Victoria Services Pty Ltd | Angiogenin Expression in Plants |
CA2839932C (en) | 2011-06-07 | 2022-07-05 | Ibio, Inc. | In vivo de-glycosylation of recombinant proteins by co-expression with pngase f |
JP2013040138A (ja) * | 2011-08-17 | 2013-02-28 | Univ Of Tsukuba | 活性化型リコンビナント花粉アレルゲンの作製方法 |
WO2014030165A1 (en) | 2012-08-23 | 2014-02-27 | Transalgae Israel Ltd. | Transgenic microalgae and use thereof for oral delivery of proteins |
EP3104885A4 (en) | 2014-02-12 | 2017-08-30 | Transalgae (Israel) Ltd | Algal based edible vaccines |
CN106460052B (zh) * | 2014-05-14 | 2021-07-16 | 海德堡鲁普雷希特卡尔斯大学 | 双链核酸的合成 |
FR3021328B1 (fr) * | 2014-05-23 | 2018-01-05 | Angany Inc. | Production commerciale de l'allergene amb a1 par expression transitoire chez les plantes |
CN104561353B (zh) * | 2015-01-29 | 2017-01-11 | 中国农业科学院蔬菜花卉研究所 | 与甘蓝育性紧密连锁的InDel标记及其检测方法和应用 |
CN110603046B (zh) * | 2016-03-20 | 2022-10-18 | 宾夕法尼亚州立大学托管会 | 用于提高高等植物叶绿体中转基因表达的密码子优化和核糖体图谱分析 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5451513A (en) * | 1990-05-01 | 1995-09-19 | The State University of New Jersey Rutgers | Method for stably transforming plastids of multicellular plants |
GB9319429D0 (en) * | 1993-09-21 | 1993-11-03 | London Health Ass | Methods and products for controlling immune responses in mammals |
US5576198A (en) * | 1993-12-14 | 1996-11-19 | Calgene, Inc. | Controlled expression of transgenic constructs in plant plastids |
FR2736930B1 (fr) * | 1995-07-17 | 1997-09-19 | Biocem | Procede de production, par des cellules vegetales, de proteines heminiques, proteines ainsi obtenues et produits contenant ces proteines |
WO1997004123A1 (en) * | 1995-07-19 | 1997-02-06 | Gel Tech Group Inc. | Collagen compound production in plants |
ZA965786B (en) * | 1995-07-19 | 1997-01-27 | Kimberly Clark Co | Nonwoven barrier and method of making the same |
CA2225652C (en) * | 1995-08-10 | 2007-11-20 | Pal Maliga | Nuclear-encoded transcription system in plastids of higher plants |
AU732479B2 (en) * | 1996-03-06 | 2001-04-26 | Rutgers University | Plastid transformation in arabidopsis thaliana |
CA2261577A1 (en) * | 1996-08-09 | 1998-02-19 | Calgene, Inc. | Methods for producing carotenoid compounds and speciality oils in plant seeds |
CA2263730A1 (en) * | 1996-08-15 | 1998-02-19 | Agrivax Incorporated | Delivery of tolerogenic antigens via edible plants or plant-derived products |
JP2002513275A (ja) * | 1996-09-12 | 2002-05-08 | ノバルティス アクチエンゲゼルシャフト | セルロース分解性酵素を発現するトランスジェニック植物 |
JP2002513283A (ja) * | 1997-01-17 | 2002-05-08 | ザ スクリップス リサーチ インスティテュート | 組換え分子の発現に有用なrna結合タンパク質及び結合部位 |
ATE296355T1 (de) * | 1997-08-07 | 2005-06-15 | Univ Auburn | Universelle integrations- und expressionsvektoren für chloroplasten, transformierte pflanzen und produkte hiervon |
ATE360072T1 (de) * | 1998-07-10 | 2007-05-15 | Calgene Llc | Expression eukarotischer peptide in pflanzenplastiden |
-
1999
- 1999-10-05 CN CN99813154A patent/CN1330718A/zh active Pending
- 1999-10-05 EP EP99950626A patent/EP1117817A2/en not_active Withdrawn
- 1999-10-05 WO PCT/EP1999/007414 patent/WO2000020612A2/en not_active Application Discontinuation
- 1999-10-05 CA CA002344269A patent/CA2344269A1/en not_active Abandoned
- 1999-10-05 IL IL14204199A patent/IL142041A0/xx unknown
- 1999-10-05 TR TR2001/01032T patent/TR200101032T2/xx unknown
- 1999-10-05 HU HU0103616A patent/HUP0103616A3/hu unknown
- 1999-10-05 AR ARP990105036A patent/AR020717A1/es unknown
- 1999-10-05 RU RU2001111881/13A patent/RU2001111881A/ru not_active Application Discontinuation
- 1999-10-05 AU AU63340/99A patent/AU758817B2/en not_active Ceased
- 1999-10-05 JP JP2000574707A patent/JP2002526116A/ja active Pending
- 1999-10-05 PL PL99347904A patent/PL347904A1/xx not_active Application Discontinuation
- 1999-10-05 KR KR1020017004448A patent/KR20010085901A/ko not_active Application Discontinuation
- 1999-10-05 BR BR9915919-8A patent/BR9915919A/pt not_active IP Right Cessation
-
2003
- 2003-01-15 AU AU2003200126A patent/AU2003200126A1/en not_active Abandoned
- 2003-10-27 RU RU2003131696/13A patent/RU2003131696A/ru not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL142041A0 (en) | 2002-03-10 |
WO2000020612A2 (en) | 2000-04-13 |
HUP0103616A3 (en) | 2003-07-28 |
WO2000020612A3 (en) | 2000-07-06 |
PL347904A1 (en) | 2002-04-22 |
AU2003200126A1 (en) | 2003-04-17 |
TR200101032T2 (tr) | 2001-10-22 |
JP2002526116A (ja) | 2002-08-20 |
EP1117817A2 (en) | 2001-07-25 |
AU2003200126A9 (en) | 2003-04-17 |
RU2001111881A (ru) | 2003-06-20 |
CA2344269A1 (en) | 2000-04-13 |
AU6334099A (en) | 2000-04-26 |
RU2003131696A (ru) | 2005-04-20 |
AU758817B2 (en) | 2003-04-03 |
KR20010085901A (ko) | 2001-09-07 |
CN1330718A (zh) | 2002-01-09 |
HUP0103616A2 (hu) | 2002-01-28 |
BR9915919A (pt) | 2001-08-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |