HUP0102395A2 - Izom- és csontrendszeri gyengeség kezelésére alkalmas szelektív ösztrogén receptor modulátorok és növekedési hormon szekretagógok (GHS) kombinációját tartalmazó gyógyszerkészítmények - Google Patents
Izom- és csontrendszeri gyengeség kezelésére alkalmas szelektív ösztrogén receptor modulátorok és növekedési hormon szekretagógok (GHS) kombinációját tartalmazó gyógyszerkészítményekInfo
- Publication number
- HUP0102395A2 HUP0102395A2 HU0102395A HUP0102395A HUP0102395A2 HU P0102395 A2 HUP0102395 A2 HU P0102395A2 HU 0102395 A HU0102395 A HU 0102395A HU P0102395 A HUP0102395 A HU P0102395A HU P0102395 A2 HUP0102395 A2 HU P0102395A2
- Authority
- HU
- Hungary
- Prior art keywords
- compound
- ghs
- serm
- growth hormone
- estrogen receptor
- Prior art date
Links
- 239000003324 growth hormone secretagogue Substances 0.000 title abstract 3
- 208000036119 Frailty Diseases 0.000 title 1
- 206010003549 asthenia Diseases 0.000 title 1
- 239000002834 estrogen receptor modulator Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 102100033367 Appetite-regulating hormone Human genes 0.000 abstract 2
- 101710111255 Appetite-regulating hormone Proteins 0.000 abstract 2
- 210000000988 bone and bone Anatomy 0.000 abstract 2
- 210000003205 muscle Anatomy 0.000 abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229940095743 selective estrogen receptor modulator Drugs 0.000 abstract 2
- 239000000333 selective estrogen receptor modulator Substances 0.000 abstract 2
- 125000004938 5-pyridyl group Chemical group N1=CC=CC(=C1)* 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 208000001164 Osteoporotic Fractures Diseases 0.000 abstract 1
- WFKAJVHLWXSISD-UHFFFAOYSA-N anhydrous dimethyl-acetamide Natural products CC(C)C(N)=O WFKAJVHLWXSISD-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- GXESHMAMLJKROZ-IAPPQJPRSA-N lasofoxifene Chemical compound C1([C@@H]2[C@@H](C3=CC=C(C=C3CC2)O)C=2C=CC(OCCN3CCCC3)=CC=2)=CC=CC=C1 GXESHMAMLJKROZ-IAPPQJPRSA-N 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000003387 muscular Effects 0.000 abstract 1
- 230000011164 ossification Effects 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8942498P | 1998-06-16 | 1998-06-16 | |
| PCT/IB1999/000796 WO1999065488A1 (en) | 1998-06-16 | 1999-05-03 | Therapeutic combinations of (selective) estrogen receptor modulators (serm) and growth hormone secretagogues (ghs) for treating musculoskeletal frailty |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP0102395A2 true HUP0102395A2 (hu) | 2001-11-28 |
Family
ID=22217565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0102395A HUP0102395A2 (hu) | 1998-06-16 | 1999-05-03 | Izom- és csontrendszeri gyengeség kezelésére alkalmas szelektív ösztrogén receptor modulátorok és növekedési hormon szekretagógok (GHS) kombinációját tartalmazó gyógyszerkészítmények |
Country Status (29)
| Country | Link |
|---|---|
| EP (1) | EP1085867A1 (zh) |
| JP (1) | JP2002518328A (zh) |
| KR (1) | KR20010052817A (zh) |
| CN (1) | CN1305378A (zh) |
| AP (1) | AP9901581A0 (zh) |
| AR (1) | AR018868A1 (zh) |
| AU (1) | AU3342099A (zh) |
| BG (1) | BG105128A (zh) |
| BR (1) | BR9911357A (zh) |
| CA (1) | CA2335112A1 (zh) |
| CO (1) | CO5070586A1 (zh) |
| EA (1) | EA200001189A1 (zh) |
| GT (1) | GT199900083A (zh) |
| HR (1) | HRP20000857A2 (zh) |
| HU (1) | HUP0102395A2 (zh) |
| ID (1) | ID26726A (zh) |
| IL (1) | IL139587A0 (zh) |
| IS (1) | IS5727A (zh) |
| MA (1) | MA26648A1 (zh) |
| NO (1) | NO20006381L (zh) |
| OA (1) | OA11569A (zh) |
| PA (1) | PA8472101A1 (zh) |
| PE (1) | PE20000633A1 (zh) |
| PL (1) | PL345064A1 (zh) |
| SK (1) | SK18902000A3 (zh) |
| TN (1) | TNSN99118A1 (zh) |
| UY (1) | UY25557A1 (zh) |
| WO (1) | WO1999065488A1 (zh) |
| ZA (1) | ZA993973B (zh) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1004306A3 (en) * | 1998-08-06 | 2000-06-07 | Pfizer Products Inc. | Estrogen agonists/antagonists |
| JP2004507502A (ja) | 2000-08-30 | 2004-03-11 | ファイザー・プロダクツ・インク | 成長ホルモン分泌促進物質のための徐放性製剤 |
| IL145106A0 (en) * | 2000-08-30 | 2002-06-30 | Pfizer Prod Inc | Intermittent administration of a geowth hormone secretagogue |
| US7524866B2 (en) | 2001-11-29 | 2009-04-28 | Gtx, Inc. | Prevention and treatment of androgen—deprivation induced osteoporosis |
| EP1666033B1 (en) * | 2001-11-29 | 2008-12-31 | GTX, Inc. | Prevention and treatment of androgen-deprivation induced osteoporosis |
| US7476653B2 (en) | 2003-06-18 | 2009-01-13 | Tranzyme Pharma, Inc. | Macrocyclic modulators of the ghrelin receptor |
| CU23558A1 (es) | 2006-02-28 | 2010-07-20 | Ct Ingenieria Genetica Biotech | Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento |
| JP2010518090A (ja) | 2007-02-09 | 2010-05-27 | トランザイム・ファーマ，インコーポレイテッド | 大環状グレリン受容体修飾因子およびその使用方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA51676C2 (uk) * | 1995-11-02 | 2002-12-16 | Пфайзер Інк. | (-)цис-6(s)-феніл-5(r)[4-(2-піролідин-1-ілетокси)феніл]-5,6,7,8-тетрагідронафталін-2-ол d-тартрат, спосіб його одержання, спосіб лікування захворювань, що піддаються лікуванню агоністами естрогену, та фармацевтична композиція |
| TW432073B (en) * | 1995-12-28 | 2001-05-01 | Pfizer | Pyrazolopyridine compounds |
| HN1996000101A (es) * | 1996-02-28 | 1997-06-26 | Inc Pfizer | Terapia combinada para la osteoporosis |
-
1999
- 1999-05-03 JP JP2000554368A patent/JP2002518328A/ja active Pending
- 1999-05-03 CA CA002335112A patent/CA2335112A1/en not_active Abandoned
- 1999-05-03 PL PL99345064A patent/PL345064A1/xx unknown
- 1999-05-03 WO PCT/IB1999/000796 patent/WO1999065488A1/en not_active Application Discontinuation
- 1999-05-03 KR KR1020007014140A patent/KR20010052817A/ko not_active Application Discontinuation
- 1999-05-03 OA OA1200000346A patent/OA11569A/en unknown
- 1999-05-03 SK SK1890-2000A patent/SK18902000A3/sk unknown
- 1999-05-03 BR BR9911357-0A patent/BR9911357A/pt not_active Application Discontinuation
- 1999-05-03 AU AU33420/99A patent/AU3342099A/en not_active Abandoned
- 1999-05-03 IL IL13958799A patent/IL139587A0/xx unknown
- 1999-05-03 EP EP99914723A patent/EP1085867A1/en not_active Withdrawn
- 1999-05-03 CN CN99807381A patent/CN1305378A/zh active Pending
- 1999-05-03 ID IDW20002604A patent/ID26726A/id unknown
- 1999-05-03 HU HU0102395A patent/HUP0102395A2/hu unknown
- 1999-05-03 EA EA200001189A patent/EA200001189A1/ru unknown
- 1999-05-07 PA PA19998472101A patent/PA8472101A1/es unknown
- 1999-06-10 AP APAP/P/1999/001581A patent/AP9901581A0/en unknown
- 1999-06-11 PE PE1999000522A patent/PE20000633A1/es not_active Application Discontinuation
- 1999-06-11 UY UY25557A patent/UY25557A1/es not_active Application Discontinuation
- 1999-06-14 GT GT199900083A patent/GT199900083A/es unknown
- 1999-06-15 AR ARP990102847A patent/AR018868A1/es not_active Application Discontinuation
- 1999-06-15 ZA ZA9903973A patent/ZA993973B/xx unknown
- 1999-06-15 TN TNTNSN99118A patent/TNSN99118A1/fr unknown
- 1999-06-15 MA MA25622A patent/MA26648A1/fr unknown
- 1999-06-16 CO CO99037624A patent/CO5070586A1/es unknown
-
2000
- 2000-11-24 IS IS5727A patent/IS5727A/is unknown
- 2000-12-14 NO NO20006381A patent/NO20006381L/no not_active Application Discontinuation
- 2000-12-14 HR HR20000857A patent/HRP20000857A2/hr not_active Application Discontinuation
-
2001
- 2001-01-08 BG BG105128A patent/BG105128A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ID26726A (id) | 2001-02-01 |
| PL345064A1 (en) | 2001-11-19 |
| EP1085867A1 (en) | 2001-03-28 |
| TNSN99118A1 (fr) | 2005-11-10 |
| IL139587A0 (en) | 2002-02-10 |
| NO20006381D0 (no) | 2000-12-14 |
| GT199900083A (es) | 2000-12-05 |
| AU3342099A (en) | 2000-01-05 |
| WO1999065488A1 (en) | 1999-12-23 |
| SK18902000A3 (sk) | 2001-12-03 |
| CA2335112A1 (en) | 1999-12-23 |
| BG105128A (en) | 2001-11-30 |
| EA200001189A1 (ru) | 2001-06-25 |
| MA26648A1 (fr) | 2004-12-20 |
| JP2002518328A (ja) | 2002-06-25 |
| AR018868A1 (es) | 2001-12-12 |
| KR20010052817A (ko) | 2001-06-25 |
| ZA993973B (en) | 2000-12-15 |
| CO5070586A1 (es) | 2001-08-28 |
| OA11569A (en) | 2004-07-01 |
| CN1305378A (zh) | 2001-07-25 |
| BR9911357A (pt) | 2001-03-13 |
| HRP20000857A2 (en) | 2001-10-31 |
| AP9901581A0 (en) | 1999-06-30 |
| IS5727A (is) | 2000-11-24 |
| PE20000633A1 (es) | 2000-07-26 |
| UY25557A1 (es) | 2001-01-31 |
| PA8472101A1 (es) | 2000-09-29 |
| NO20006381L (no) | 2000-12-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EE04018B1 (et) | Tieno[2,3-d]pürimidiindioonid, nende valmistamisemeetod ja neid sisaldavad ravimkoostised | |
| CO4600739A1 (es) | Formulaciones liquidas orales a base de alendronato | |
| EP0962225A3 (en) | Use of phentolamine for the manufacture of a medicament for the treatment of erectile dysfunction | |
| HUP0003349A2 (hu) | Mellékpajzsmirigy-hormon peptidanalógok, ezeket hatóanyagként tartalmazó gyógyászati készítmények és alkalmazásuk | |
| TNSN98111A1 (fr) | Tartrate d'un dipeptide substitue, procede pour sa preparation et compositions pharmaceutiques le contenant. | |
| IL132153A0 (en) | Novel compounds | |
| CO4750658A1 (es) | Formulaciones farmaceuticas y procedimientos que comprenden amoxicilina y una sal de acido clavulanico | |
| EA200100154A1 (ru) | Бензоциклогептены, способ их получения, содержащие их фармацевтические препараты и их применение для получения лекарственных средств | |
| PL334228A1 (en) | Derivatives of pyrrolo[3,4-d]pyrimidinone and their application as drugs | |
| HUP0001922A2 (hu) | Pirazolo[4,3-c]-piridin származékok, ezeket tartalmazó inzulinrezisztencia elleni gyógyszerkészítmények, intermedierek és eljárás előállításukra | |
| HUP0102395A2 (hu) | Izom- és csontrendszeri gyengeség kezelésére alkalmas szelektív ösztrogén receptor modulátorok és növekedési hormon szekretagógok (GHS) kombinációját tartalmazó gyógyszerkészítmények | |
| HUP0003840A2 (hu) | Szabályozott hatóanyagleadású gyógyászati készítmények | |
| HUP0102759A2 (hu) | Szelektív ösztrogénreceptor-modulátorból és paratiroid-hormonból álló terápiás kombináció | |
| HUP0102505A2 (hu) | Szelektív ösztrogén receptor modulátorokat (SERM) és növekedési hormon kiválasztását fokozó anyagokat (GHS) együtt tartalmazó csontváz-izomzati gyengeség kezelésére szolgáló gyógyszerkombinációk | |
| HUP9902421A2 (hu) | Nyálkahártya-viszkozitást optimalizáló és bélfunkciót stimuláló hatású készítmények | |
| HUP0100542A2 (hu) | Progesztogént és anti-progesztogént tartalmazó kit, eljárás előállítására és a vegyületek alkalmazása fogamzásgátló szer előállítására | |
| EA200400691A1 (ru) | Получение чистых стереоизомеров трицикло[5,2,1,02,6]дец-9-ил-ксантогената и содержащие их лекарственные средства | |
| CA2274381A1 (en) | Therapeutic combinations comprising a selective estrogen receptor modulator and prostaglandin e2 | |
| TH57984A3 (th) | การรวมในทางการรักษาซี่งประกอบด้วยตัวปรับตัวรับเอสโตรเจนแบบคัดเลือกและฮอร์โมนพาราไธรอยด์ | |
| ECSP993021A (es) | Combinaciones terapeuticas para la fragilidad musculoesqueletica | |
| WO2002034203A3 (en) | Novel derivatives of phenyl 4-aminosalicylate and method of making the same | |
| ES2007415A6 (es) | Procewdimiento de obtencioon de citidina-difosfo-dimetiletanolamina. | |
| TH48282A (th) | การรักษาโรคของการให้ยาประกอบร่วมกันของโรคกระดูกพรุน | |
| IT1229204B (it) | Prodotto farmaceutico analgesico e anti infiammatorio per la cura delle affezioni dell'apparato muscolo scheletrico e metodo per ottenere detto prodotto. | |
| HU9802142D0 (en) | Use of na+/h+ -ion-exchange inhibitors for producing pharmaceutical compositions for treating and profilacting diseases of the central nerve system |