CO5070586A1 - Combinaciones terapeuticas para la fragilidad musculoesque- letica - Google Patents

Combinaciones terapeuticas para la fragilidad musculoesque- letica

Info

Publication number
CO5070586A1
CO5070586A1 CO99037624A CO99037624A CO5070586A1 CO 5070586 A1 CO5070586 A1 CO 5070586A1 CO 99037624 A CO99037624 A CO 99037624A CO 99037624 A CO99037624 A CO 99037624A CO 5070586 A1 CO5070586 A1 CO 5070586A1
Authority
CO
Colombia
Prior art keywords
fragility
compositions
musculoesque
letica
pyridin
Prior art date
Application number
CO99037624A
Other languages
English (en)
Inventor
Hua Zhu Ke
Li Mei
Pan Lydia Codetta
Thompson David Duane
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of CO5070586A1 publication Critical patent/CO5070586A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Esta invención se refiere a composición de combinación farmacéutica y procedimientos, que comprenden (-)-cis-6-fenil-5-( 4-(2-pirrolidin-1-il-etoxi)-fenil)-5, 6, 7, 8- tetrahidronaftaleno-2-ol o una sal farmacéuticamente aceptable del mismo y 2-amino-N-( 1 (R)-(2,,4-difluoro-benciloximetil)-2-oxo-2-(3-oxo-3a(R)-piridin-2-ilmetil)-2-(2, 2, 2-trifluoro-etil)-2, 3, 3a, 4, 6, 7-hexahidropirazolo[4,3-c]piridin-5-il)-etil)-2-metil-propionamida o una sal farmacéuticamente aceptable de la misma, a procedimientos de uso de tales composiciones y a estuches que contiene tales composiciones. Las composiciones son útiles para el tratamiento de la fragilidad musculoesquelética, incluyendo la osteoporosis, fracturas osteoporóticas, reducción de masa ósea, fragilidad y reducción de masa muscular. <EMI FILE="99037624_1" ID="1" IMF=JPEG >
CO99037624A 1998-06-16 1999-06-16 Combinaciones terapeuticas para la fragilidad musculoesque- letica CO5070586A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8942498P 1998-06-16 1998-06-16

Publications (1)

Publication Number Publication Date
CO5070586A1 true CO5070586A1 (es) 2001-08-28

Family

ID=22217565

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99037624A CO5070586A1 (es) 1998-06-16 1999-06-16 Combinaciones terapeuticas para la fragilidad musculoesque- letica

Country Status (29)

Country Link
EP (1) EP1085867A1 (es)
JP (1) JP2002518328A (es)
KR (1) KR20010052817A (es)
CN (1) CN1305378A (es)
AP (1) AP9901581A0 (es)
AR (1) AR018868A1 (es)
AU (1) AU3342099A (es)
BG (1) BG105128A (es)
BR (1) BR9911357A (es)
CA (1) CA2335112A1 (es)
CO (1) CO5070586A1 (es)
EA (1) EA200001189A1 (es)
GT (1) GT199900083A (es)
HR (1) HRP20000857A2 (es)
HU (1) HUP0102395A2 (es)
ID (1) ID26726A (es)
IL (1) IL139587A0 (es)
IS (1) IS5727A (es)
MA (1) MA26648A1 (es)
NO (1) NO20006381D0 (es)
OA (1) OA11569A (es)
PA (1) PA8472101A1 (es)
PE (1) PE20000633A1 (es)
PL (1) PL345064A1 (es)
SK (1) SK18902000A3 (es)
TN (1) TNSN99118A1 (es)
UY (1) UY25557A1 (es)
WO (1) WO1999065488A1 (es)
ZA (1) ZA993973B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1004306A3 (en) * 1998-08-06 2000-06-07 Pfizer Products Inc. Estrogen agonists/antagonists
IL145106A0 (en) * 2000-08-30 2002-06-30 Pfizer Prod Inc Intermittent administration of a geowth hormone secretagogue
BR0113626A (pt) 2000-08-30 2003-06-17 Pfizer Prod Inc Formulações de liberação sustentada para secretores de hormÈnio do crescimento
US7524866B2 (en) 2001-11-29 2009-04-28 Gtx, Inc. Prevention and treatment of androgen—deprivation induced osteoporosis
ES2319785T3 (es) * 2001-11-29 2009-05-12 Gtx, Inc. Prevencion y tratamiento de osteoporosis inducida por privacion de androgenos.
US7476653B2 (en) 2003-06-18 2009-01-13 Tranzyme Pharma, Inc. Macrocyclic modulators of the ghrelin receptor
CU23558A1 (es) 2006-02-28 2010-07-20 Ct Ingenieria Genetica Biotech Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento
EA200901077A1 (ru) 2007-02-09 2010-04-30 Транзим Фарма, Инк. Макроциклические модуляторы грелинового рецептора и их применение

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA51676C2 (uk) * 1995-11-02 2002-12-16 Пфайзер Інк. (-)цис-6(s)-феніл-5(r)[4-(2-піролідин-1-ілетокси)феніл]-5,6,7,8-тетрагідронафталін-2-ол d-тартрат, спосіб його одержання, спосіб лікування захворювань, що піддаються лікуванню агоністами естрогену, та фармацевтична композиція
TW432073B (en) * 1995-12-28 2001-05-01 Pfizer Pyrazolopyridine compounds
HN1996000101A (es) * 1996-02-28 1997-06-26 Inc Pfizer Terapia combinada para la osteoporosis

Also Published As

Publication number Publication date
UY25557A1 (es) 2001-01-31
PA8472101A1 (es) 2000-09-29
ID26726A (id) 2001-02-01
EP1085867A1 (en) 2001-03-28
IS5727A (is) 2000-11-24
WO1999065488A1 (en) 1999-12-23
PL345064A1 (en) 2001-11-19
TNSN99118A1 (fr) 2005-11-10
EA200001189A1 (ru) 2001-06-25
JP2002518328A (ja) 2002-06-25
PE20000633A1 (es) 2000-07-26
BG105128A (en) 2001-11-30
BR9911357A (pt) 2001-03-13
HUP0102395A2 (hu) 2001-11-28
KR20010052817A (ko) 2001-06-25
AP9901581A0 (en) 1999-06-30
IL139587A0 (en) 2002-02-10
HRP20000857A2 (en) 2001-10-31
NO20006381L (no) 2000-12-14
OA11569A (en) 2004-07-01
CN1305378A (zh) 2001-07-25
MA26648A1 (fr) 2004-12-20
CA2335112A1 (en) 1999-12-23
AU3342099A (en) 2000-01-05
AR018868A1 (es) 2001-12-12
NO20006381D0 (no) 2000-12-14
ZA993973B (en) 2000-12-15
SK18902000A3 (sk) 2001-12-03
GT199900083A (es) 2000-12-05

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