HUP0100964A2 - Gyógyszerészeti kombinációk tramadollal - Google Patents
Gyógyszerészeti kombinációk tramadollalInfo
- Publication number
- HUP0100964A2 HUP0100964A2 HU0100964A HUP0100964A HUP0100964A2 HU P0100964 A2 HUP0100964 A2 HU P0100964A2 HU 0100964 A HU0100964 A HU 0100964A HU P0100964 A HUP0100964 A HU P0100964A HU P0100964 A2 HUP0100964 A2 HU P0100964A2
- Authority
- HU
- Hungary
- Prior art keywords
- pharmaceutical combinations
- combinations containing
- containing tramadol
- migraine
- pharmaceutically acceptable
- Prior art date
Links
- TVYLLZQTGLZFBW-ZBFHGGJFSA-N (R,R)-tramadol Chemical compound COC1=CC=CC([C@]2(O)[C@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-ZBFHGGJFSA-N 0.000 title abstract 2
- 229960004380 tramadol Drugs 0.000 title abstract 2
- TVYLLZQTGLZFBW-GOEBONIOSA-N tramadol Natural products COC1=CC=CC([C@@]2(O)[C@@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-GOEBONIOSA-N 0.000 title abstract 2
- 208000019695 Migraine disease Diseases 0.000 abstract 2
- 206010027599 migraine Diseases 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 206010019233 Headaches Diseases 0.000 abstract 1
- 206010021518 Impaired gastric emptying Diseases 0.000 abstract 1
- 206010028813 Nausea Diseases 0.000 abstract 1
- 208000007542 Paresis Diseases 0.000 abstract 1
- 206010047700 Vomiting Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000002111 antiemetic agent Substances 0.000 abstract 1
- 229940125683 antiemetic agent Drugs 0.000 abstract 1
- 238000002512 chemotherapy Methods 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 229960001253 domperidone Drugs 0.000 abstract 1
- FGXWKSZFVQUSTL-UHFFFAOYSA-N domperidone Chemical compound C12=CC=CC=C2NC(=O)N1CCCN(CC1)CCC1N1C2=CC=C(Cl)C=C2NC1=O FGXWKSZFVQUSTL-UHFFFAOYSA-N 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 231100000869 headache Toxicity 0.000 abstract 1
- 229960004503 metoclopramide Drugs 0.000 abstract 1
- TTWJBBZEZQICBI-UHFFFAOYSA-N metoclopramide Chemical compound CCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC TTWJBBZEZQICBI-UHFFFAOYSA-N 0.000 abstract 1
- 230000008693 nausea Effects 0.000 abstract 1
- 230000002980 postoperative effect Effects 0.000 abstract 1
- 239000002325 prokinetic agent Substances 0.000 abstract 1
- 230000008673 vomiting Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/133—Amines having hydroxy groups, e.g. sphingosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Abstract
A jelen találmány hatóanyagként tramadolt vagy egy enantiomerjét vagyegy gyógyszerészetileg elfogadható sóját és metocloprámidot,domperidont vagy más prokinetikus és antiemetikus hatású anyagot vagyezek gyógyszerészetileg elfogadható sóját tartalmazó gyógyszerészetikombinációk alkalmazására vonatkozik migrén és migrénszerű fejfájások,valamint olyan fájdalmas állapotok kezelésére, amelyek émelygésselés/vagy hányással (például kemoterápia alatt) és/vagy késleltetettgyomorkiürüléssel járnak együtt (például posztoperatív, diabetikusgyomorparézisnél). Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19807535A DE19807535A1 (de) | 1998-02-21 | 1998-02-21 | Pharmazeutische Kombinationen mit Tramadol |
PCT/DE1999/000428 WO1999042095A1 (de) | 1998-02-21 | 1999-02-17 | Pharmazeutische kombinationen mit tramadol |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0100964A2 true HUP0100964A2 (hu) | 2001-08-28 |
HUP0100964A3 HUP0100964A3 (en) | 2003-09-29 |
HU225656B1 HU225656B1 (en) | 2007-05-29 |
Family
ID=7858642
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0100964A HU225656B1 (en) | 1998-02-21 | 1999-02-17 | Pharmaceutical combinations containing tramadol |
Country Status (26)
Country | Link |
---|---|
EP (1) | EP1056448B1 (hu) |
JP (1) | JP2002503689A (hu) |
KR (1) | KR100567154B1 (hu) |
CN (1) | CN1141937C (hu) |
AR (1) | AR018102A1 (hu) |
AT (1) | ATE257700T1 (hu) |
AU (1) | AU748993B2 (hu) |
BG (1) | BG64888B1 (hu) |
BR (1) | BR9909211A (hu) |
CZ (1) | CZ291941B6 (hu) |
DE (2) | DE19807535A1 (hu) |
DK (1) | DK1056448T3 (hu) |
EA (1) | EA002166B1 (hu) |
ES (1) | ES2212549T3 (hu) |
HK (1) | HK1035143A1 (hu) |
HU (1) | HU225656B1 (hu) |
IL (1) | IL137505A (hu) |
NO (1) | NO327860B1 (hu) |
NZ (1) | NZ506020A (hu) |
PL (1) | PL204075B1 (hu) |
PT (1) | PT1056448E (hu) |
SK (1) | SK284937B6 (hu) |
TR (1) | TR200002411T2 (hu) |
TW (1) | TWI228040B (hu) |
WO (1) | WO1999042095A1 (hu) |
ZA (1) | ZA991212B (hu) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1329590A (zh) * | 1998-12-02 | 2002-01-02 | 达尔文发现有限公司 | 治疗产品及其应用 |
DE19940944B4 (de) * | 1999-08-31 | 2006-10-12 | Grünenthal GmbH | Retardierte, orale, pharmazeutische Darreichungsformen |
WO2001064202A2 (en) * | 2000-03-01 | 2001-09-07 | Euro-Celtique S.A. | Tramadol for the treatment of functional gastrointestinal disorders |
US6451813B1 (en) | 2001-01-26 | 2002-09-17 | R. T. Alamo Ventures I, Llc | Treatment of gastroparesis in certain patient groups |
DE10108122A1 (de) | 2001-02-21 | 2002-10-02 | Gruenenthal Gmbh | Arzneimittel auf Basis von Tramadol |
DE10361596A1 (de) * | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
DE102004020220A1 (de) * | 2004-04-22 | 2005-11-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
US7553858B2 (en) * | 2003-12-17 | 2009-06-30 | Meda Pharma Gmbh & Co. Kg | Combination of flupirtine and tramadol |
CA2665841C (en) | 2006-10-09 | 2016-04-05 | Charleston Laboratories, Inc. | Pharmaceutical compositions |
JP5714910B2 (ja) | 2008-01-09 | 2015-05-07 | チャールストン ラボラトリーズ,インコーポレイテッド | 薬学的組成物 |
EP2756756B1 (en) | 2008-04-28 | 2016-01-06 | Zogenix, Inc. | Novel formulations for treatment of migraine |
US20130213393A1 (en) | 2009-12-22 | 2013-08-22 | Evoke Pharma, Inc. | Nasal formulations of metoclopramide |
CA2767576C (en) | 2009-07-08 | 2020-03-10 | Charleston Laboratories Inc. | Pharmaceutical compositions comprising an antiemetic and an opioid analgesic |
US20150290211A1 (en) * | 2014-04-10 | 2015-10-15 | Locl Pharma, Inc. | Pharmaceutical compositions |
US10179109B2 (en) | 2016-03-04 | 2019-01-15 | Charleston Laboratories, Inc. | Pharmaceutical compositions comprising 5HT receptor agonist and antiemetic particulates |
WO2018112061A1 (en) * | 2016-12-15 | 2018-06-21 | Evoke Pharma, Inc. | Treatment of moderate and severe gastroparesis |
JP7195660B1 (ja) | 2021-09-09 | 2022-12-26 | 壽製薬株式会社 | 口腔内崩壊錠 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4309408A (en) * | 1978-11-16 | 1982-01-05 | Beecham Group Limited | Effervescent powders |
AU528098B2 (en) * | 1978-11-16 | 1983-04-14 | Beecham Group Plc | Analgesic tablet |
CA2020018A1 (en) * | 1990-06-27 | 1991-12-28 | Don L. Simmons | Method and composition for treating the migraine complex |
GB9214184D0 (en) * | 1992-07-03 | 1992-08-12 | Smithkline Beecham Plc | Pharmaceuticals |
FR2712809B1 (fr) * | 1993-11-26 | 1996-04-12 | Union Pharma Scient Appl | Nouvelle composition pharmaceutique destinée à la préparation d'une poudre stable contenant, à titre d'ingrédient actif, une association d'acide acétylsalicylique et de métoclopramide. |
FR2720936B1 (fr) * | 1994-06-08 | 1997-04-30 | Synthelabo | Poudres à base de métoclopramide et de paracétamol ou de dérivés d'acide acétylsalicylique. |
GB9523566D0 (en) * | 1995-11-17 | 1996-01-17 | Euro Celtique Sa | Pharmaceutical formulation |
FR2741532B1 (fr) * | 1995-11-28 | 1998-08-21 | Bouchara Sa | Nouvelles compositions pharmaceutiques a action antimigraineuse et leur mode de preparation |
GB2313309B (en) * | 1996-05-24 | 2000-01-26 | Ninh Thuy On | Pharmaceutical compositions comprising a nonsteroidal anti-inflammatory drug and domperidone in the treatment of migraine |
-
1998
- 1998-02-21 DE DE19807535A patent/DE19807535A1/de not_active Withdrawn
-
1999
- 1999-02-16 ZA ZA9901212A patent/ZA991212B/xx unknown
- 1999-02-17 JP JP2000532112A patent/JP2002503689A/ja active Pending
- 1999-02-17 PT PT99916744T patent/PT1056448E/pt unknown
- 1999-02-17 IL IL13750599A patent/IL137505A/xx not_active IP Right Cessation
- 1999-02-17 WO PCT/DE1999/000428 patent/WO1999042095A1/de active IP Right Grant
- 1999-02-17 HU HU0100964A patent/HU225656B1/hu not_active IP Right Cessation
- 1999-02-17 BR BR9909211-5A patent/BR9909211A/pt not_active Application Discontinuation
- 1999-02-17 EP EP99916744A patent/EP1056448B1/de not_active Expired - Lifetime
- 1999-02-17 CZ CZ20002939A patent/CZ291941B6/cs not_active IP Right Cessation
- 1999-02-17 CN CNB998031224A patent/CN1141937C/zh not_active Expired - Fee Related
- 1999-02-17 SK SK1217-2000A patent/SK284937B6/sk not_active IP Right Cessation
- 1999-02-17 KR KR1020007009151A patent/KR100567154B1/ko not_active IP Right Cessation
- 1999-02-17 PL PL342546A patent/PL204075B1/pl unknown
- 1999-02-17 EA EA200000862A patent/EA002166B1/ru not_active IP Right Cessation
- 1999-02-17 DE DE59908305T patent/DE59908305D1/de not_active Expired - Lifetime
- 1999-02-17 AT AT99916744T patent/ATE257700T1/de active
- 1999-02-17 ES ES99916744T patent/ES2212549T3/es not_active Expired - Lifetime
- 1999-02-17 AU AU35148/99A patent/AU748993B2/en not_active Ceased
- 1999-02-17 NZ NZ506020A patent/NZ506020A/en not_active IP Right Cessation
- 1999-02-17 DK DK99916744T patent/DK1056448T3/da active
- 1999-02-17 TR TR2000/02411T patent/TR200002411T2/xx unknown
- 1999-02-20 TW TW088102487A patent/TWI228040B/zh not_active IP Right Cessation
- 1999-02-23 AR ARP990100707A patent/AR018102A1/es not_active Application Discontinuation
-
2000
- 2000-08-18 NO NO20004143A patent/NO327860B1/no not_active IP Right Cessation
- 2000-09-12 BG BG104758A patent/BG64888B1/bg unknown
-
2001
- 2001-08-17 HK HK01105795A patent/HK1035143A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUP0100964A2 (hu) | Gyógyszerészeti kombinációk tramadollal | |
HK1080459A1 (en) | Novel pyrimidineamide derivatives and the use thereof | |
TW200510375A (en) | New compounds | |
HUP0302131A2 (hu) | Gyógyászati tramadolsók, ezeket tartalmazó gyógyszerkészítmények | |
MXPA02012272A (es) | Compuestos heterociclicos que son inhibidores de la enzima dipeptidilpeptidasa-iv. | |
MY133238A (en) | Monoamine reuptake inhibitors for treatment for cns disorders | |
WO2002053187A3 (en) | Methods and transdermal compositions for pain relief | |
HUP0102728A2 (hu) | Módszerek és transzdermális készítmények fájdalom csillapítására | |
WO2003015779A3 (de) | Matrixkontrolliertes transdermales therapeutisches system zur anwendung von pramipexol und ropinirol | |
GB0111186D0 (en) | Novel compounds | |
MXPA05007379A (es) | Metodo para tratar nauseas, vomito, esfuerzo por vomitar o cualquier combinacion de los mismos. | |
AU2002214389A1 (en) | Pharmaceutical composition containing honey for the treatment of wounds | |
WO2002070464A3 (en) | Hydrazones and their therapeutic use | |
HK1086548A1 (en) | Deuterated catecholamine derivatives and medicaments comprising said compounds | |
BR0211063A (pt) | Sais de derivados anticonvulsivantes | |
GR1004358B (el) | Ανυδρη κρυσταλλικη μορφη της βαλακyκλοβιρης υδροχλωρικης | |
SE0102440D0 (sv) | New compound | |
NO20025015L (no) | Et pyridin-1-oksidderivat, og fremgangsmåte for dets overföring til farmasöytisk effektive forbindelser | |
MXPA03004111A (es) | Composiciones de n-(1 -metiletilaminocarbonil)-4 -(3-metilfenilamino) -3-piridil-sulfonamida y oligosacaridos ciclicos con una mayor liberacion. | |
DK0742716T3 (da) | Farmaceutisk sammensætning til systemisk transdermal indgivelse med det aktive middel morphin-6-glucuronid | |
WO2001023385A3 (en) | Novel tropane analogs | |
AU7393201A (en) | Drug combination for the treatment of headache comprising a non-steroidal anti-inflammatory drug | |
AP2003002897A0 (en) | Processes and intermediates for preparing benzyl epoxides | |
WO2002066025A3 (de) | Wirkstoffkombination aus dem racemat des tramadols und dem (+)-o-desmethyltramadol | |
MXPA03010919A (es) | Uso de acetil l-carnitina para preparacion de medicamento para terapia preventiva del dolor. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
HC9A | Change of name, address |
Owner name: MEDA PHARMA GMBH & CO. KG, DE Free format text: FORMER OWNER(S): ASTA MEDICA AG, DE; ASTA MEDICA HEALTH PRODUCTS GMBH & CO. KG, DE; VIATRIS GMBH & CO. KG, DE |
|
MM4A | Lapse of definitive patent protection due to non-payment of fees |