BR9909211A - Combinações farmacêuticas com tramadol - Google Patents

Combinações farmacêuticas com tramadol

Info

Publication number
BR9909211A
BR9909211A BR9909211-5A BR9909211A BR9909211A BR 9909211 A BR9909211 A BR 9909211A BR 9909211 A BR9909211 A BR 9909211A BR 9909211 A BR9909211 A BR 9909211A
Authority
BR
Brazil
Prior art keywords
tramadol
pharmaceutical combinations
migraines
pharmaceutically
salts
Prior art date
Application number
BR9909211-5A
Other languages
English (en)
Inventor
Marc Raber
Helmut Momberger
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of BR9909211A publication Critical patent/BR9909211A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/133—Amines having hydroxy groups, e.g. sphingosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Patente de Invenção: <B>"COMBINAçõES FARMACêUTICAS COM TRAMADOL"<D>. A presente invenção refere-se ao emprego de combinações farmacêuticas, que são empregadas como substâncias ativas tramadol ou um de seus enanciómeros ou um de seus sais farmacêuticamente aceitáveis e metoclopramida, domperidona ou outra substância pro-cinética e antiemética eficaz ou um de seus sais farmaceuticamente aceitáveis, para tratamento das enxaquecas e dores de cabeça na forma de enxaquecas e/ou um retardamento do esvaziamento associado do estómago (por exemplo, no pós-operatório, em gastroparesia diabética).
BR9909211-5A 1998-02-21 1999-02-17 Combinações farmacêuticas com tramadol BR9909211A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19807535A DE19807535A1 (de) 1998-02-21 1998-02-21 Pharmazeutische Kombinationen mit Tramadol
PCT/DE1999/000428 WO1999042095A1 (de) 1998-02-21 1999-02-17 Pharmazeutische kombinationen mit tramadol

Publications (1)

Publication Number Publication Date
BR9909211A true BR9909211A (pt) 2000-11-14

Family

ID=7858642

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9909211-5A BR9909211A (pt) 1998-02-21 1999-02-17 Combinações farmacêuticas com tramadol

Country Status (26)

Country Link
EP (1) EP1056448B1 (pt)
JP (1) JP2002503689A (pt)
KR (1) KR100567154B1 (pt)
CN (1) CN1141937C (pt)
AR (1) AR018102A1 (pt)
AT (1) ATE257700T1 (pt)
AU (1) AU748993B2 (pt)
BG (1) BG64888B1 (pt)
BR (1) BR9909211A (pt)
CZ (1) CZ291941B6 (pt)
DE (2) DE19807535A1 (pt)
DK (1) DK1056448T3 (pt)
EA (1) EA002166B1 (pt)
ES (1) ES2212549T3 (pt)
HK (1) HK1035143A1 (pt)
HU (1) HU225656B1 (pt)
IL (1) IL137505A (pt)
NO (1) NO327860B1 (pt)
NZ (1) NZ506020A (pt)
PL (1) PL204075B1 (pt)
PT (1) PT1056448E (pt)
SK (1) SK284937B6 (pt)
TR (1) TR200002411T2 (pt)
TW (1) TWI228040B (pt)
WO (1) WO1999042095A1 (pt)
ZA (1) ZA991212B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1329590A (zh) * 1998-12-02 2002-01-02 达尔文发现有限公司 治疗产品及其应用
DE19940944B4 (de) * 1999-08-31 2006-10-12 Grünenthal GmbH Retardierte, orale, pharmazeutische Darreichungsformen
WO2001064202A2 (en) * 2000-03-01 2001-09-07 Euro-Celtique S.A. Tramadol for the treatment of functional gastrointestinal disorders
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
DE10108122A1 (de) 2001-02-21 2002-10-02 Gruenenthal Gmbh Arzneimittel auf Basis von Tramadol
DE10361596A1 (de) * 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102004020220A1 (de) * 2004-04-22 2005-11-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
US7553858B2 (en) * 2003-12-17 2009-06-30 Meda Pharma Gmbh & Co. Kg Combination of flupirtine and tramadol
CA2665841C (en) 2006-10-09 2016-04-05 Charleston Laboratories, Inc. Pharmaceutical compositions
JP5714910B2 (ja) 2008-01-09 2015-05-07 チャールストン ラボラトリーズ，インコーポレイテッド 薬学的組成物
EP2756756B1 (en) 2008-04-28 2016-01-06 Zogenix, Inc. Novel formulations for treatment of migraine
US20130213393A1 (en) 2009-12-22 2013-08-22 Evoke Pharma, Inc. Nasal formulations of metoclopramide
CA2767576C (en) 2009-07-08 2020-03-10 Charleston Laboratories Inc. Pharmaceutical compositions comprising an antiemetic and an opioid analgesic
US20150290211A1 (en) * 2014-04-10 2015-10-15 Locl Pharma, Inc. Pharmaceutical compositions
US10179109B2 (en) 2016-03-04 2019-01-15 Charleston Laboratories, Inc. Pharmaceutical compositions comprising 5HT receptor agonist and antiemetic particulates
WO2018112061A1 (en) * 2016-12-15 2018-06-21 Evoke Pharma, Inc. Treatment of moderate and severe gastroparesis
JP7195660B1 (ja) 2021-09-09 2022-12-26 壽製薬株式会社 口腔内崩壊錠

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4309408A (en) * 1978-11-16 1982-01-05 Beecham Group Limited Effervescent powders
AU528098B2 (en) * 1978-11-16 1983-04-14 Beecham Group Plc Analgesic tablet
CA2020018A1 (en) * 1990-06-27 1991-12-28 Don L. Simmons Method and composition for treating the migraine complex
GB9214184D0 (en) * 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
FR2712809B1 (fr) * 1993-11-26 1996-04-12 Union Pharma Scient Appl Nouvelle composition pharmaceutique destinée à la préparation d'une poudre stable contenant, à titre d'ingrédient actif, une association d'acide acétylsalicylique et de métoclopramide.
FR2720936B1 (fr) * 1994-06-08 1997-04-30 Synthelabo Poudres à base de métoclopramide et de paracétamol ou de dérivés d'acide acétylsalicylique.
GB9523566D0 (en) * 1995-11-17 1996-01-17 Euro Celtique Sa Pharmaceutical formulation
FR2741532B1 (fr) * 1995-11-28 1998-08-21 Bouchara Sa Nouvelles compositions pharmaceutiques a action antimigraineuse et leur mode de preparation
GB2313309B (en) * 1996-05-24 2000-01-26 Ninh Thuy On Pharmaceutical compositions comprising a nonsteroidal anti-inflammatory drug and domperidone in the treatment of migraine

Also Published As

Publication number Publication date
HUP0100964A3 (en) 2003-09-29
CN1291092A (zh) 2001-04-11
DE59908305D1 (de) 2004-02-19
NO20004143L (no) 2000-09-27
TR200002411T2 (tr) 2000-12-21
EA002166B1 (ru) 2001-12-24
ZA991212B (en) 1999-08-03
AU3514899A (en) 1999-09-06
BG104758A (en) 2001-04-30
CN1141937C (zh) 2004-03-17
KR100567154B1 (ko) 2006-04-04
PL204075B1 (pl) 2009-12-31
HU225656B1 (en) 2007-05-29
PL342546A1 (en) 2001-06-18
EP1056448B1 (de) 2004-01-14
JP2002503689A (ja) 2002-02-05
NZ506020A (en) 2002-05-31
NO327860B1 (no) 2009-10-05
CZ291941B6 (cs) 2003-06-18
AR018102A1 (es) 2001-10-31
SK284937B6 (sk) 2006-02-02
BG64888B1 (bg) 2006-08-31
IL137505A (en) 2005-07-25
HUP0100964A2 (hu) 2001-08-28
ES2212549T3 (es) 2004-07-16
PT1056448E (pt) 2004-05-31
EA200000862A1 (ru) 2001-02-26
ATE257700T1 (de) 2004-01-15
AU748993B2 (en) 2002-06-13
KR20010041110A (ko) 2001-05-15
DE19807535A1 (de) 1999-08-26
SK12172000A3 (sk) 2001-04-09
HK1035143A1 (en) 2001-11-16
EP1056448A1 (de) 2000-12-06
CZ20002939A3 (cs) 2000-12-13
DK1056448T3 (da) 2004-05-17
NO20004143D0 (no) 2000-08-18
WO1999042095A1 (de) 1999-08-26
TWI228040B (en) 2005-02-21
IL137505A0 (en) 2001-07-24

Similar Documents

Publication Publication Date Title
BR9909211A (pt) Combinações farmacêuticas com tramadol
BR9713785A (pt) Composto, uso do mesmo, agente de diagnóstico, composição farmacêutica, e, processos para a preparação de um composto e para o tratamento da dor, de distúrbios gastrointestinais e de lesões na coluna vertebral.
BR0116201A (pt) Composto, processo para a preparação de um composto, composição farmacêutica que compreende o composto, utilização do composto, processo para o tratamento e profilaxia de distúrbios e para o tratamento de obesidade
BR9912240A (pt) Benzocicloheptenos, processo para a sua preparação, preparados farmacêuticos, que contêm os mesmos bem como seu emprego para a preparação de medicamentos
BR9907866A (pt) Composição farmacêutica compreendendo uma combinação de metformina e fibrato, e seu uso para a preparação de medicinas destinadas a reduzir a hiperglicemia
BRPI9914741A (pt) n-(2-aril-proprionil)-sulfonamidas, usos e composições farmacêuticas contendo as mesmas.
MXPA03007712A (es) Sales farmaceuticas.
NO20010531L (no) Medisinske aerosolformuleringer
BR9714381A (pt) Derivados de 6-fenilpiridil-2-amina
BR0014441A (pt) Composições que apresentam estabilidade aperfeiçoada
CA2386690A1 (en) Pharmaceutical tramadol salts
BR0307291A (pt) Composto; processo para a preparação de um composto; composição farmacêutica; uso de um composto; método para o tratamento e profilaxia de distúrbios diversos e de obesidade em um humano
BR0008958A (pt) Inibidores de reabsorção de monoamina para otratamento de distúrbios do snc
BR9914507A (pt) Concentrado de substância ativa com formoterol, adequado para armazenagem
DK1100805T3 (da) Nitratsalte som lægemiddel
BR0009693A (pt) Mistura para a preparação de espumas duras de poliuretano
BR9814299A (pt) Aminobiguanidas e o seu uso para desinfetarlentes de contato e preservar composiçõesfarmacêuticas
BR0314353A (pt) Compostos, composições farmacêuticas, uso de um ou mais compostos em combinação com outros compostos farmacologicamente ativos, e, método para tratar um paciente que sofre de um distúrbio
BR0012951A (pt) Agonistas de retinóides seletivos
BR9913072A (pt) Sistemas de anel azacìclico, composição farmacêutica, e, processo para induzir a analgesia
WO2002030467A3 (en) Pharmaceutical composition containing honey for the treatment of wounds
BR0115045A (pt) Compostos, processo para sua preparação, composição farmacêutica que compreende os mesmos, sua utilização, processo para o tratamento e profilaxia de artrite, diabetes, distúrbios alimentares e obesidade
BR0311646A (pt) Derivados de ácido n-benzoilureido cinâmico, processo para sua preparação e seu emprego
PT1051159E (pt) Composicoes farmaceuticas solidas contendo miltefosina para administracao oral no tratamento de leishmaniose
BR9712705A (pt) Composição para o tratamento da asma, contendo loratadina e um descongestionante

Legal Events

Date Code Title Description
TC Change of name
PC Transfer

Owner name: ASTA MEDICA HEALTH PRODUCTS GMBH & CO. KG (DE)

TC Change of name
B25G Requested change of headquarter approved

Owner name: VIATRIS GMBH AND CO. KG (DE)

Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 020050037237/RJ DE 17/05/2005.

B25D Requested change of name of applicant approved

Owner name: MEDA PHARMA GMBH AND CO. KG (DE)

Free format text: ALTERADO DE: VIATRIS GMBH AND CO. KG

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DE INT.CL: A61K 31/37, A61K 31/166, A61K 31/454, A61P 25/06, A61P 1/08

Ipc: A61K 31/137 (2007.10), A61K 31/166 (2007.10), A61K

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE O MESMO NAO ATENDE AO DISPOSTO NOS ARTIGOS 8O E 13 DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.