BG104758A - Pharmaceutical combinations containing tramadol - Google Patents
Pharmaceutical combinations containing tramadolInfo
- Publication number
- BG104758A BG104758A BG104758A BG10475800A BG104758A BG 104758 A BG104758 A BG 104758A BG 104758 A BG104758 A BG 104758A BG 10475800 A BG10475800 A BG 10475800A BG 104758 A BG104758 A BG 104758A
- Authority
- BG
- Bulgaria
- Prior art keywords
- pharmaceutical combinations
- combinations containing
- migraine
- pharmaceutically acceptable
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/133—Amines having hydroxy groups, e.g. sphingosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to the use of pharmaceutical combinations containing as active ingredient tramadol or one of its enantiomers or one of its pharmaceutically acceptable salts and metoclopramide, domperidone or other substances having a prokinetic and antiemic action or one of their pharmaceutically acceptable salts. Said pharmaceutical combinations are used for the treatment of migraine and migraine-like headaches and for the treatment of pain accompanied by nausea and/or vomiting (for example during chemotherapy) and/or delayed gastric emptying (for example postoperatively in diabetic gastroparesis). 11 claims, 1 figures
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19807535A DE19807535A1 (en) | 1998-02-21 | 1998-02-21 | Drug combination for treating migraine, migraine-type headaches or pain accompanied by nausea, vomiting or delayed gastric emptying |
Publications (2)
Publication Number | Publication Date |
---|---|
BG104758A true BG104758A (en) | 2001-04-30 |
BG64888B1 BG64888B1 (en) | 2006-08-31 |
Family
ID=7858642
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG104758A BG64888B1 (en) | 1998-02-21 | 2000-09-12 | Pharmaceutical combinations containing tramadol |
Country Status (26)
Country | Link |
---|---|
EP (1) | EP1056448B1 (en) |
JP (1) | JP2002503689A (en) |
KR (1) | KR100567154B1 (en) |
CN (1) | CN1141937C (en) |
AR (1) | AR018102A1 (en) |
AT (1) | ATE257700T1 (en) |
AU (1) | AU748993B2 (en) |
BG (1) | BG64888B1 (en) |
BR (1) | BR9909211A (en) |
CZ (1) | CZ291941B6 (en) |
DE (2) | DE19807535A1 (en) |
DK (1) | DK1056448T3 (en) |
EA (1) | EA002166B1 (en) |
ES (1) | ES2212549T3 (en) |
HK (1) | HK1035143A1 (en) |
HU (1) | HU225656B1 (en) |
IL (1) | IL137505A (en) |
NO (1) | NO327860B1 (en) |
NZ (1) | NZ506020A (en) |
PL (1) | PL204075B1 (en) |
PT (1) | PT1056448E (en) |
SK (1) | SK284937B6 (en) |
TR (1) | TR200002411T2 (en) |
TW (1) | TWI228040B (en) |
WO (1) | WO1999042095A1 (en) |
ZA (1) | ZA991212B (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP0104420A2 (en) * | 1998-12-02 | 2002-08-28 | Darwin Discovery Ltd | Therapeutic composition containing a new form of tramadol and its use |
DE19940944B4 (en) * | 1999-08-31 | 2006-10-12 | Grünenthal GmbH | Retarded, oral, pharmaceutical dosage forms |
WO2001064202A2 (en) * | 2000-03-01 | 2001-09-07 | Euro-Celtique S.A. | Tramadol for the treatment of functional gastrointestinal disorders |
US6451813B1 (en) | 2001-01-26 | 2002-09-17 | R. T. Alamo Ventures I, Llc | Treatment of gastroparesis in certain patient groups |
DE10108122A1 (en) | 2001-02-21 | 2002-10-02 | Gruenenthal Gmbh | Medicines based on tramadol |
DE102004020220A1 (en) * | 2004-04-22 | 2005-11-10 | Grünenthal GmbH | Process for the preparation of a secured against misuse, solid dosage form |
DE10361596A1 (en) * | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Process for producing an anti-abuse dosage form |
US7553858B2 (en) * | 2003-12-17 | 2009-06-30 | Meda Pharma Gmbh & Co. Kg | Combination of flupirtine and tramadol |
JP2010522135A (en) | 2006-10-09 | 2010-07-01 | チャールストン ラボラトリーズ,インコーポレイテッド | Pharmaceutical composition |
JP5714910B2 (en) | 2008-01-09 | 2015-05-07 | チャールストン ラボラトリーズ,インコーポレイテッド | Pharmaceutical composition |
CA2722743A1 (en) | 2008-04-28 | 2009-11-05 | Zogenix, Inc. | Novel formulations for treatment of migraine |
US20130213393A1 (en) | 2009-12-22 | 2013-08-22 | Evoke Pharma, Inc. | Nasal formulations of metoclopramide |
CA2767576C (en) | 2009-07-08 | 2020-03-10 | Charleston Laboratories Inc. | Pharmaceutical compositions comprising an antiemetic and an opioid analgesic |
WO2015157738A1 (en) * | 2014-04-10 | 2015-10-15 | Charleston Laboratories, Inc. | Pharmaceutical compositions |
US10179109B2 (en) | 2016-03-04 | 2019-01-15 | Charleston Laboratories, Inc. | Pharmaceutical compositions comprising 5HT receptor agonist and antiemetic particulates |
WO2018112061A1 (en) * | 2016-12-15 | 2018-06-21 | Evoke Pharma, Inc. | Treatment of moderate and severe gastroparesis |
JP7195660B1 (en) | 2021-09-09 | 2022-12-26 | 壽製薬株式会社 | Orally disintegrating tablet |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU528098B2 (en) * | 1978-11-16 | 1983-04-14 | Beecham Group Plc | Analgesic tablet |
AU528310B2 (en) * | 1978-11-16 | 1983-04-21 | Beecham Group Plc | Composition of paracetamol and metoclopramide |
CA2020018A1 (en) * | 1990-06-27 | 1991-12-28 | Don L. Simmons | Method and composition for treating the migraine complex |
GB9214184D0 (en) * | 1992-07-03 | 1992-08-12 | Smithkline Beecham Plc | Pharmaceuticals |
FR2712809B1 (en) * | 1993-11-26 | 1996-04-12 | Union Pharma Scient Appl | New pharmaceutical composition intended for the preparation of a stable powder containing, as active ingredient, a combination of acetylsalicylic acid and metoclopramide. |
FR2720936B1 (en) * | 1994-06-08 | 1997-04-30 | Synthelabo | Powders based on metoclopramide and paracetamol or acetylsalicylic acid derivatives. |
GB9523566D0 (en) * | 1995-11-17 | 1996-01-17 | Euro Celtique Sa | Pharmaceutical formulation |
FR2741532B1 (en) * | 1995-11-28 | 1998-08-21 | Bouchara Sa | NOVEL PHARMACEUTICAL COMPOSITIONS WITH ANTIMIGRAINE ACTION AND THEIR METHOD OF PREPARATION |
GB2313309B (en) * | 1996-05-24 | 2000-01-26 | Ninh Thuy On | Pharmaceutical compositions comprising a nonsteroidal anti-inflammatory drug and domperidone in the treatment of migraine |
-
1998
- 1998-02-21 DE DE19807535A patent/DE19807535A1/en not_active Withdrawn
-
1999
- 1999-02-16 ZA ZA9901212A patent/ZA991212B/en unknown
- 1999-02-17 DE DE59908305T patent/DE59908305D1/en not_active Expired - Lifetime
- 1999-02-17 PL PL342546A patent/PL204075B1/en unknown
- 1999-02-17 EP EP99916744A patent/EP1056448B1/en not_active Expired - Lifetime
- 1999-02-17 KR KR1020007009151A patent/KR100567154B1/en not_active IP Right Cessation
- 1999-02-17 NZ NZ506020A patent/NZ506020A/en not_active IP Right Cessation
- 1999-02-17 PT PT99916744T patent/PT1056448E/en unknown
- 1999-02-17 AT AT99916744T patent/ATE257700T1/en active
- 1999-02-17 CZ CZ20002939A patent/CZ291941B6/en not_active IP Right Cessation
- 1999-02-17 ES ES99916744T patent/ES2212549T3/en not_active Expired - Lifetime
- 1999-02-17 AU AU35148/99A patent/AU748993B2/en not_active Ceased
- 1999-02-17 HU HU0100964A patent/HU225656B1/en not_active IP Right Cessation
- 1999-02-17 TR TR2000/02411T patent/TR200002411T2/en unknown
- 1999-02-17 WO PCT/DE1999/000428 patent/WO1999042095A1/en active IP Right Grant
- 1999-02-17 SK SK1217-2000A patent/SK284937B6/en not_active IP Right Cessation
- 1999-02-17 EA EA200000862A patent/EA002166B1/en not_active IP Right Cessation
- 1999-02-17 IL IL13750599A patent/IL137505A/en not_active IP Right Cessation
- 1999-02-17 BR BR9909211-5A patent/BR9909211A/en not_active Application Discontinuation
- 1999-02-17 CN CNB998031224A patent/CN1141937C/en not_active Expired - Fee Related
- 1999-02-17 JP JP2000532112A patent/JP2002503689A/en active Pending
- 1999-02-17 DK DK99916744T patent/DK1056448T3/en active
- 1999-02-20 TW TW088102487A patent/TWI228040B/en not_active IP Right Cessation
- 1999-02-23 AR ARP990100707A patent/AR018102A1/en not_active Application Discontinuation
-
2000
- 2000-08-18 NO NO20004143A patent/NO327860B1/en not_active IP Right Cessation
- 2000-09-12 BG BG104758A patent/BG64888B1/en unknown
-
2001
- 2001-08-17 HK HK01105795A patent/HK1035143A1/en not_active IP Right Cessation
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