MD457G2 - New naphtiridin derivatives , preparation method, pharmaceutical compositions containing these derivatives, their utilization as antireproductive medicines - Google Patents

New naphtiridin derivatives , preparation method, pharmaceutical compositions containing these derivatives, their utilization as antireproductive medicines

Info

Publication number
MD457G2
MD457G2 MD95-0113A MD950113A MD457G2 MD 457 G2 MD457 G2 MD 457G2 MD 950113 A MD950113 A MD 950113A MD 457 G2 MD457 G2 MD 457G2
Authority
MD
Moldova
Prior art keywords
derivatives
antireproductive
naphtiridin
medicines
utilization
Prior art date
Application number
MD95-0113A
Other languages
Romanian (ro)
Russian (ru)
Other versions
MD457F1 (en
Inventor
Nicole Bru-Magniez
Michele Launay
Jean-Marie Teulon
Original Assignee
Laboratoires Upsa, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Upsa, S.A. filed Critical Laboratoires Upsa, S.A.
Priority claimed from PCT/FR1994/000763 external-priority patent/WO1995000513A1/en
Publication of MD457F1 publication Critical patent/MD457F1/en
Publication of MD457G2 publication Critical patent/MD457G2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention relates to the derivatives of formula:as well as to additive salts thereof and to using thereof in the therapy as remedy having antireproductive characteristics which allow the efficient therapy of cancer deseases, psoreasis or others cell reproductivity pathologies.
MD95-0113A 1993-06-25 1994-06-24 New naphtiridin derivatives , preparation method, pharmaceutical compositions containing these derivatives, their utilization as antireproductive medicines MD457G2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9307746A FR2706898B1 (en) 1993-06-25 1993-06-25
PCT/FR1994/000763 WO1995000513A1 (en) 1993-06-25 1994-06-24 Antiproliferative naphthyridines

Publications (2)

Publication Number Publication Date
MD457F1 MD457F1 (en) 1996-08-30
MD457G2 true MD457G2 (en) 1997-04-30

Family

ID=9448553

Family Applications (1)

Application Number Title Priority Date Filing Date
MD95-0113A MD457G2 (en) 1993-06-25 1994-06-24 New naphtiridin derivatives , preparation method, pharmaceutical compositions containing these derivatives, their utilization as antireproductive medicines

Country Status (14)

Country Link
US (1) US5364860A (en)
EP (1) EP0705261A1 (en)
JP (1) JPH08511793A (en)
CN (1) CN1125444A (en)
AU (1) AU7127594A (en)
CA (1) CA2161436A1 (en)
CZ (1) CZ337295A3 (en)
EE (1) EE9400439A (en)
FI (1) FI954982A (en)
FR (1) FR2706898B1 (en)
HU (1) HUT74162A (en)
MD (1) MD457G2 (en)
NZ (1) NZ268383A (en)
SK (1) SK155395A3 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL117923A (en) * 1995-05-03 2000-06-01 Warner Lambert Co Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds
US5620981A (en) * 1995-05-03 1997-04-15 Warner-Lambert Company Pyrido [2,3-D]pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation
CA2252536C (en) * 1996-04-25 2010-04-06 Nissan Chemical Industries, Ltd. Ethylene derivatives and pesticides containing said derivatives
EP1003745B1 (en) * 1997-08-20 2004-12-29 Warner-Lambert Company Llc Naphthyridinones for inhibiting protein tyrosine kinase and cell cycle kinase mediated cellular proliferation
BR112018017117B1 (en) * 2016-03-15 2021-11-16 Shionogi & Co., Ltd. PRODUCTION METHOD FOR PHENOXYETHANOL DERIVATIVES

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0267691A2 (en) * 1986-10-15 1988-05-18 Schering Corporation Use of 1-substituted naphthyridine and pyridopyrazine derivatives for the preparation of medicaments with immunosuppressor activity.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2567520B1 (en) * 1984-07-11 1987-01-02 Carpibem NOVEL PHENYL-NAPHTHYRIDINES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM, IN PARTICULAR ANTI-ULCERS
NZ218773A (en) * 1986-01-06 1990-05-28 Carpibem 3-methyl-2-oxo-1-(substituted phenyl)-naphthyridines and pharmaceutical compositions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0267691A2 (en) * 1986-10-15 1988-05-18 Schering Corporation Use of 1-substituted naphthyridine and pyridopyrazine derivatives for the preparation of medicaments with immunosuppressor activity.

Also Published As

Publication number Publication date
SK155395A3 (en) 1996-09-04
HUT74162A (en) 1996-11-28
EP0705261A1 (en) 1996-04-10
CN1125444A (en) 1996-06-26
CZ337295A3 (en) 1996-03-13
JPH08511793A (en) 1996-12-10
EE9400439A (en) 1996-06-17
FI954982A0 (en) 1995-10-19
US5364860A (en) 1994-11-15
AU7127594A (en) 1995-01-17
HU9503776D0 (en) 1996-02-28
FI954982A (en) 1995-12-27
NZ268383A (en) 1997-03-24
MD457F1 (en) 1996-08-30
FR2706898A1 (en) 1994-12-30
CA2161436A1 (en) 1995-01-05
FR2706898B1 (en) 1995-09-08

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Legal Events

Date Code Title Description
FG3A Granted patent for invention
IF99 Valid patent on 19990615

Free format text: EXPIRES: 20141230