HUP0001750A2 - Eljárás sztérikusan gátolt 4-amino-piperidinek tisztítására - Google Patents
Eljárás sztérikusan gátolt 4-amino-piperidinek tisztításáraInfo
- Publication number
- HUP0001750A2 HUP0001750A2 HU0001750A HUP0001750A HUP0001750A2 HU P0001750 A2 HUP0001750 A2 HU P0001750A2 HU 0001750 A HU0001750 A HU 0001750A HU P0001750 A HUP0001750 A HU P0001750A HU P0001750 A2 HUP0001750 A2 HU P0001750A2
- Authority
- HU
- Hungary
- Prior art keywords
- purifying
- sterically hindered
- piperidine derivatives
- amino piperidines
- distillation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- BCIIMDOZSUCSEN-UHFFFAOYSA-N piperidin-4-amine Chemical class NC1CCNCC1 BCIIMDOZSUCSEN-UHFFFAOYSA-N 0.000 title 1
- 150000003053 piperidines Chemical class 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 238000004821 distillation Methods 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Removal Of Specific Substances (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Cephalosporin Compounds (AREA)
Abstract
A találmány tárgya egy eljárás az (I) általános képletű nyerspiperidinszármazékok -, ahol R1-R4 jelentése 1-6 szénatomosalkilcsoport, valamint R1 és R2 és/vagy R3 és R4 együtt egy 2-5szénatomos alkilénláncot képezhet - tisztítására, amit az jellemez,hogy az első lépésben a magas forráspontú komponenseket és adottesetben a vizet a nyers piperidinszármazékokból desztillációvalelkülönítik, a második lépésben 0,01-5 tömegszázalékos mennyiségbenadnak egy redukálószert, az első lépés szerint kapott termék tömegérevonatkoztatva és végül a harmadik lépésben a piperidinszármazékokatdesztillációval nyerik ki. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19622269A DE19622269A1 (de) | 1996-06-03 | 1996-06-03 | Verfahren zur Reinigung von sterisch gehinderten 4-Aminopiperidinen |
PCT/EP1997/002822 WO1997046529A1 (de) | 1996-06-03 | 1997-05-30 | Verfahren zur reinigung von sterisch gehinderten 4-amino-piperidinen |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0001750A2 true HUP0001750A2 (hu) | 2000-10-28 |
HUP0001750A3 HUP0001750A3 (en) | 2003-07-28 |
Family
ID=7796031
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0001750A HUP0001750A3 (en) | 1996-06-03 | 1997-05-30 | Process for purifying sterically hindered 4-amino piperidines |
Country Status (21)
Country | Link |
---|---|
US (1) | US6011157A (hu) |
EP (1) | EP0906281B1 (hu) |
JP (1) | JP2000511551A (hu) |
CN (1) | CN1165524C (hu) |
AT (1) | ATE209632T1 (hu) |
AU (1) | AU716280B2 (hu) |
BR (1) | BR9709470A (hu) |
CA (1) | CA2257095C (hu) |
CO (1) | CO4790110A1 (hu) |
CZ (1) | CZ290805B6 (hu) |
DE (2) | DE19622269A1 (hu) |
EA (1) | EA001160B1 (hu) |
ES (1) | ES2169397T3 (hu) |
HU (1) | HUP0001750A3 (hu) |
ID (1) | ID16996A (hu) |
MY (1) | MY121277A (hu) |
NZ (1) | NZ332160A (hu) |
PL (1) | PL185707B1 (hu) |
PT (1) | PT906281E (hu) |
UA (1) | UA48229C2 (hu) |
WO (1) | WO1997046529A1 (hu) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19743433C1 (de) * | 1997-10-01 | 1999-04-22 | Basf Ag | Verfahren zur Reinigung von 4-Amino-piperidinen |
DE19912031A1 (de) | 1999-03-17 | 2000-09-21 | Basf Ag | Verwendung von quervernetztem Polyvinylpyrrolidon zur Erhöhung der Zerfallgeschwindigkeit von kompakten teilchenförmigen Wasch- und Reinigungsmitteln |
DE102008040045A1 (de) | 2008-02-01 | 2009-08-06 | Evonik Degussa Gmbh | Verfahren zur Herstellung von 4-Amino-2,2,6,6-tetramethylpiperidin |
EP2085384A1 (de) | 2008-02-01 | 2009-08-05 | Evonik Degussa GmbH | Verfahren zur Herstellung von 4-Amino-2,2,6,6-tetramethylpiperidin |
WO2022184399A1 (en) | 2021-03-05 | 2022-09-09 | Basf Se | Process for preparing n,n'-bis(2,2,6,6-tetramethylpiperidin-4-yl)hexane-1,6-diamine |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL266799A (hu) * | 1961-07-07 | |||
US3159276A (en) * | 1963-05-03 | 1964-12-01 | Allied Chem | Ethanolamines |
US3222310A (en) * | 1963-11-20 | 1965-12-07 | Metal Hydrides Inc | Method for inhibiting color formation in amines |
JPS5522465B2 (hu) * | 1973-01-24 | 1980-06-17 | ||
DE3003843A1 (de) * | 1980-02-02 | 1981-08-13 | Chemische Werke Hüls AG, 4370 Marl | Verfahren zur herstellung von 4-amino-2,2,6,6-tetramethylpiperidin |
US5208377A (en) * | 1990-09-24 | 1993-05-04 | Elf Atochem North America, Inc. | Purification and decolorization of off-color alkyl alkanolamines |
ES2067106T3 (es) * | 1990-09-24 | 1995-03-16 | Atochem North America | Purificacion y decoloracion de alquil-alcanolaminas de intenso color. |
RU1811527C (ru) * | 1991-02-20 | 1993-04-23 | Научно-исследовательский институт химикатов для полимерных материалов | Способ выделени высокочистого 2,2,6,6-тетраметил-4-аминопиперидина |
-
1996
- 1996-06-03 DE DE19622269A patent/DE19622269A1/de not_active Withdrawn
-
1997
- 1997-05-30 AT AT97927086T patent/ATE209632T1/de not_active IP Right Cessation
- 1997-05-30 US US09/180,626 patent/US6011157A/en not_active Expired - Fee Related
- 1997-05-30 UA UA98126948A patent/UA48229C2/uk unknown
- 1997-05-30 CA CA002257095A patent/CA2257095C/en not_active Expired - Fee Related
- 1997-05-30 ES ES97927086T patent/ES2169397T3/es not_active Expired - Lifetime
- 1997-05-30 PT PT97927086T patent/PT906281E/pt unknown
- 1997-05-30 CZ CZ19983917A patent/CZ290805B6/cs not_active IP Right Cessation
- 1997-05-30 JP JP10500210A patent/JP2000511551A/ja not_active Withdrawn
- 1997-05-30 PL PL97330278A patent/PL185707B1/pl unknown
- 1997-05-30 CN CNB971942145A patent/CN1165524C/zh not_active Expired - Fee Related
- 1997-05-30 HU HU0001750A patent/HUP0001750A3/hu unknown
- 1997-05-30 BR BR9709470A patent/BR9709470A/pt not_active IP Right Cessation
- 1997-05-30 DE DE59705561T patent/DE59705561D1/de not_active Expired - Fee Related
- 1997-05-30 CO CO97030212A patent/CO4790110A1/es unknown
- 1997-05-30 EP EP97927086A patent/EP0906281B1/de not_active Expired - Lifetime
- 1997-05-30 AU AU31700/97A patent/AU716280B2/en not_active Ceased
- 1997-05-30 NZ NZ332160A patent/NZ332160A/en unknown
- 1997-05-30 EA EA199801064A patent/EA001160B1/ru not_active IP Right Cessation
- 1997-05-30 WO PCT/EP1997/002822 patent/WO1997046529A1/de active IP Right Grant
- 1997-05-31 MY MYPI97002410A patent/MY121277A/en unknown
- 1997-06-03 ID IDP971893A patent/ID16996A/id unknown
Also Published As
Publication number | Publication date |
---|---|
DE19622269A1 (de) | 1997-12-04 |
CN1165524C (zh) | 2004-09-08 |
CA2257095A1 (en) | 1997-12-11 |
ID16996A (id) | 1997-11-27 |
US6011157A (en) | 2000-01-04 |
HUP0001750A3 (en) | 2003-07-28 |
ES2169397T3 (es) | 2002-07-01 |
CZ391798A3 (cs) | 1999-03-17 |
CN1216979A (zh) | 1999-05-19 |
EA199801064A1 (ru) | 1999-06-24 |
CA2257095C (en) | 2005-02-01 |
NZ332160A (en) | 1999-09-29 |
MY121277A (en) | 2006-01-28 |
EP0906281A1 (de) | 1999-04-07 |
ATE209632T1 (de) | 2001-12-15 |
WO1997046529A1 (de) | 1997-12-11 |
UA48229C2 (uk) | 2002-08-15 |
EA001160B1 (ru) | 2000-10-30 |
CO4790110A1 (es) | 1999-05-31 |
BR9709470A (pt) | 1999-08-10 |
PT906281E (pt) | 2002-05-31 |
JP2000511551A (ja) | 2000-09-05 |
AU716280B2 (en) | 2000-02-24 |
PL330278A1 (en) | 1999-05-10 |
DE59705561D1 (de) | 2002-01-10 |
EP0906281B1 (de) | 2001-11-28 |
CZ290805B6 (cs) | 2002-10-16 |
PL185707B1 (pl) | 2003-07-31 |
AU3170097A (en) | 1998-01-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE254594T1 (de) | Verbindungen verwendbar als zwischenprodukte zur herstellung von piperidinderivate | |
DE69120500D1 (de) | Azasteroide zur Behandlung prostatischer Hypertrophie, ihre Herstellung und Verwendung | |
ATE229960T1 (de) | Verfahren zur herstellung von 13-ether-derivaten von milbemycinen und zwischenprodukte | |
DE69618792D1 (de) | N-benzyldioxothiazolidylbenzamid-derivate und verfahren zu ihrer herstellung | |
ATE205190T1 (de) | Vitamin d3-derivate und ein verfahren zu ihrer herstellung | |
DE69119875T2 (de) | Verwendung von Dioxabicyclo [3.3.0]octane Derivaten zur Herstellung eines Arzneimittels zur Hemmung des Cholesterinmetabolismus. | |
HUP0001750A2 (hu) | Eljárás sztérikusan gátolt 4-amino-piperidinek tisztítására | |
DE69527787D1 (de) | Verfahren und zwischenprodukte zur herstellung von piperazinderivaten | |
HUP9802455A2 (hu) | Piperidinvegyületek alkalmazása polipropilén előállítására | |
ATE168367T1 (de) | Vitamin-d-derivate und verfahren zu deren herstellung | |
ATE236895T1 (de) | Ringannelierte dihydropyrane, verfahren zur herstellung sowie deren verwendung | |
KR910016716A (ko) | 트리아진게 화합물 | |
DE69008473T2 (de) | Dicyclohexylethylenderivate. | |
ATE211136T1 (de) | Coumarin-derivate, verfahren zu deren herstellung und deren verwendung | |
ATE146176T1 (de) | Benzo(b)thiophen-3-yl-piperazine, verfahren zur deren herstellung und ihre verwendung als arzneimittel | |
WO2001012642A3 (de) | Nucleosidderivate und verfahren zu deren herstellung | |
HUP0101808A2 (hu) | Eljárás izomertiszta, magas helyettesítési fokú azaciklikus vegyületek sztereokémiailag szabályozott előállítására | |
DE69719673D1 (de) | D-pentofuranose-derivate und verfahren zu ihrer herstellung | |
ATE236109T1 (de) | Verfahren zur herstellung von 1,5-pentandiol- derivaten | |
HUP0000298A2 (hu) | Eljárás aril-béta-diketon-, aril-pirimidin-keton-származékok és növényvédőszerek közbenső termékeinek előállítására | |
EA199800767A1 (ru) | Производные 1(2h)хинолинкарбоновой кислоты, способ их получения и их применение в синтезе веществ, обладающих антибиотическими свойствами | |
DE3879058T2 (de) | 4-piperidincarboxamid-derivate. | |
ATE157961T1 (de) | Acetaldehyd-derivate, verfahren zu ihrer herstellung und ihre verwendung | |
KR900003178A (ko) | 세펨 화합물의 제조방법 | |
TW328090B (en) | Process for preparing 2,2-difluoroketene silyl acetals and α,α-difluoro-β-silyloxy-1,3-dioxolane-4-propanoic acid esters |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |