CO4790110A1 - Procedimiento para la purificacion de 4-amino-piperidinas estericamente inhibidas - Google Patents
Procedimiento para la purificacion de 4-amino-piperidinas estericamente inhibidasInfo
- Publication number
- CO4790110A1 CO4790110A1 CO97030212A CO97030212A CO4790110A1 CO 4790110 A1 CO4790110 A1 CO 4790110A1 CO 97030212 A CO97030212 A CO 97030212A CO 97030212 A CO97030212 A CO 97030212A CO 4790110 A1 CO4790110 A1 CO 4790110A1
- Authority
- CO
- Colombia
- Prior art keywords
- piperidines
- purification
- procedure
- stage
- esterically
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000000746 purification Methods 0.000 title abstract 2
- 150000003053 piperidines Chemical class 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 238000004821 distillation Methods 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Removal Of Specific Substances (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Procedimiento para la purificación de piperidinas de lafórmula I: en la que R1 hasta R4 significan alquilo con 1 a 6 átomos de carbono, R1 y R2 y/o R3 y R4 forman juntos una cadena de CH2 con 2 hasta 5 átomos de carbono, caracterizado porque en una primera etapa se separan sustancias de alto punto de ebullición y eventualmente agua de las piperidinas crudas por destilación, en una segunda etapa se agrega 0,01 hasta 5% en peso, con respecto al producto de la primera etapa, de un agente de reducción, y en una tercera etapa se aíslan las piperidinas por destilación.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19622269A DE19622269A1 (de) | 1996-06-03 | 1996-06-03 | Verfahren zur Reinigung von sterisch gehinderten 4-Aminopiperidinen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4790110A1 true CO4790110A1 (es) | 1999-05-31 |
Family
ID=7796031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO97030212A CO4790110A1 (es) | 1996-06-03 | 1997-05-30 | Procedimiento para la purificacion de 4-amino-piperidinas estericamente inhibidas |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6011157A (es) |
| EP (1) | EP0906281B1 (es) |
| JP (1) | JP2000511551A (es) |
| CN (1) | CN1165524C (es) |
| AT (1) | ATE209632T1 (es) |
| AU (1) | AU716280B2 (es) |
| BR (1) | BR9709470A (es) |
| CA (1) | CA2257095C (es) |
| CO (1) | CO4790110A1 (es) |
| CZ (1) | CZ290805B6 (es) |
| DE (2) | DE19622269A1 (es) |
| EA (1) | EA001160B1 (es) |
| ES (1) | ES2169397T3 (es) |
| HU (1) | HUP0001750A3 (es) |
| ID (1) | ID16996A (es) |
| MY (1) | MY121277A (es) |
| NZ (1) | NZ332160A (es) |
| PL (1) | PL185707B1 (es) |
| PT (1) | PT906281E (es) |
| UA (1) | UA48229C2 (es) |
| WO (1) | WO1997046529A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19743433C1 (de) * | 1997-10-01 | 1999-04-22 | Basf Ag | Verfahren zur Reinigung von 4-Amino-piperidinen |
| DE19912031A1 (de) | 1999-03-17 | 2000-09-21 | Basf Ag | Verwendung von quervernetztem Polyvinylpyrrolidon zur Erhöhung der Zerfallgeschwindigkeit von kompakten teilchenförmigen Wasch- und Reinigungsmitteln |
| DE102008040045A1 (de) | 2008-02-01 | 2009-08-06 | Evonik Degussa Gmbh | Verfahren zur Herstellung von 4-Amino-2,2,6,6-tetramethylpiperidin |
| EP2085384A1 (de) | 2008-02-01 | 2009-08-05 | Evonik Degussa GmbH | Verfahren zur Herstellung von 4-Amino-2,2,6,6-tetramethylpiperidin |
| CN116917272A (zh) | 2021-03-05 | 2023-10-20 | 巴斯夫欧洲公司 | 制备n,n'-二(2,2,6,6-四甲基哌啶-4-基)-1,6-己二胺的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL266799A (es) * | 1961-07-07 | |||
| US3159276A (en) * | 1963-05-03 | 1964-12-01 | Allied Chem | Ethanolamines |
| US3222310A (en) * | 1963-11-20 | 1965-12-07 | Metal Hydrides Inc | Method for inhibiting color formation in amines |
| JPS5522465B2 (es) * | 1973-01-24 | 1980-06-17 | ||
| DE3003843A1 (de) * | 1980-02-02 | 1981-08-13 | Chemische Werke Hüls AG, 4370 Marl | Verfahren zur herstellung von 4-amino-2,2,6,6-tetramethylpiperidin |
| ES2067106T3 (es) * | 1990-09-24 | 1995-03-16 | Atochem North America | Purificacion y decoloracion de alquil-alcanolaminas de intenso color. |
| US5208377A (en) * | 1990-09-24 | 1993-05-04 | Elf Atochem North America, Inc. | Purification and decolorization of off-color alkyl alkanolamines |
| RU1811527C (ru) * | 1991-02-20 | 1993-04-23 | Научно-исследовательский институт химикатов для полимерных материалов | Способ выделени высокочистого 2,2,6,6-тетраметил-4-аминопиперидина |
-
1996
- 1996-06-03 DE DE19622269A patent/DE19622269A1/de not_active Withdrawn
-
1997
- 1997-05-30 BR BR9709470A patent/BR9709470A/pt not_active IP Right Cessation
- 1997-05-30 DE DE59705561T patent/DE59705561D1/de not_active Expired - Fee Related
- 1997-05-30 EP EP97927086A patent/EP0906281B1/de not_active Expired - Lifetime
- 1997-05-30 EA EA199801064A patent/EA001160B1/ru not_active IP Right Cessation
- 1997-05-30 CO CO97030212A patent/CO4790110A1/es unknown
- 1997-05-30 AU AU31700/97A patent/AU716280B2/en not_active Ceased
- 1997-05-30 NZ NZ332160A patent/NZ332160A/en unknown
- 1997-05-30 CZ CZ19983917A patent/CZ290805B6/cs not_active IP Right Cessation
- 1997-05-30 HU HU0001750A patent/HUP0001750A3/hu unknown
- 1997-05-30 CA CA002257095A patent/CA2257095C/en not_active Expired - Fee Related
- 1997-05-30 AT AT97927086T patent/ATE209632T1/de not_active IP Right Cessation
- 1997-05-30 CN CNB971942145A patent/CN1165524C/zh not_active Expired - Fee Related
- 1997-05-30 ES ES97927086T patent/ES2169397T3/es not_active Expired - Lifetime
- 1997-05-30 US US09/180,626 patent/US6011157A/en not_active Expired - Fee Related
- 1997-05-30 PL PL97330278A patent/PL185707B1/pl unknown
- 1997-05-30 PT PT97927086T patent/PT906281E/pt unknown
- 1997-05-30 UA UA98126948A patent/UA48229C2/uk unknown
- 1997-05-30 WO PCT/EP1997/002822 patent/WO1997046529A1/de active IP Right Grant
- 1997-05-30 JP JP10500210A patent/JP2000511551A/ja not_active Withdrawn
- 1997-05-31 MY MYPI97002410A patent/MY121277A/en unknown
- 1997-06-03 ID IDP971893A patent/ID16996A/id unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL330278A1 (en) | 1999-05-10 |
| EA001160B1 (ru) | 2000-10-30 |
| AU716280B2 (en) | 2000-02-24 |
| DE59705561D1 (de) | 2002-01-10 |
| EP0906281B1 (de) | 2001-11-28 |
| EA199801064A1 (ru) | 1999-06-24 |
| CN1216979A (zh) | 1999-05-19 |
| CA2257095A1 (en) | 1997-12-11 |
| ATE209632T1 (de) | 2001-12-15 |
| AU3170097A (en) | 1998-01-05 |
| PL185707B1 (pl) | 2003-07-31 |
| NZ332160A (en) | 1999-09-29 |
| PT906281E (pt) | 2002-05-31 |
| BR9709470A (pt) | 1999-08-10 |
| MY121277A (en) | 2006-01-28 |
| CA2257095C (en) | 2005-02-01 |
| JP2000511551A (ja) | 2000-09-05 |
| UA48229C2 (uk) | 2002-08-15 |
| EP0906281A1 (de) | 1999-04-07 |
| HUP0001750A2 (hu) | 2000-10-28 |
| DE19622269A1 (de) | 1997-12-04 |
| CN1165524C (zh) | 2004-09-08 |
| CZ391798A3 (cs) | 1999-03-17 |
| HUP0001750A3 (en) | 2003-07-28 |
| US6011157A (en) | 2000-01-04 |
| WO1997046529A1 (de) | 1997-12-11 |
| ES2169397T3 (es) | 2002-07-01 |
| CZ290805B6 (cs) | 2002-10-16 |
| ID16996A (id) | 1997-11-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69525957T2 (de) | Verwendung eines ungesättigten Fettalkohols | |
| KR880008986A (ko) | D 계열 프로스타글란딘, 및 그를 함유하는 정신안정제와 최면제 | |
| ES2155566T3 (es) | Uso de derivados de rifamicina para el tratamiento de enfermedades infecciosas por clamidia. | |
| MY115307A (en) | Preparation for epidermis | |
| ATE93838T1 (de) | Triphenylmethan-derivate. | |
| DE59103664D1 (de) | Verfahren zur Inhibierung und Zerstörung von Peroxiden in Dialkylethern. | |
| DE69728544D1 (de) | Totalsynthese von acylfulvenen mit antitumorwirkung | |
| ATE60763T1 (de) | Pyrrolidinylamidesterderivate mit antiprolylendopeptidaseaktivitaet, ihre herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen. | |
| FI935944A0 (fi) | Pyratsolopyrimidin- samt pyrimidinylbisfosfonestrar som anti- inflammatorer | |
| OA09016A (fr) | Produits cathartiques. | |
| ES2154669T3 (es) | Uso de 2-fenil-3-aroilbenzotiofenos para la preparacion de un medicamento para la inhibicion de la degradacion del cartilago. | |
| SE7610038L (sv) | Miticida och aficida karboxylsyraestrar | |
| CO4790110A1 (es) | Procedimiento para la purificacion de 4-amino-piperidinas estericamente inhibidas | |
| AR025951A1 (es) | Derivados de 4-hicroxibifenil hidrazidas y métodos para preparar los derivados. | |
| NO164351C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-alkyl-l-fenyl-2-piperazinoalkylpyrazolin-3-on-forbindelser. | |
| RU94027686A (ru) | Производные ксантина, способ их получения и содержащая их фармацевтическая композиция | |
| AU1902797A (en) | New acids and esters of diosmetin and pharmaceutical compositions containing them | |
| FI870090A (fi) | Laongkedjade alkylresorcinolfosfiter. | |
| PT97766A (pt) | Processo depreparacao de derivados de isocromano e de composicoes farmaceuticas que os contem | |
| DE68914917D1 (de) | Tetracyclische Antidepressiva. | |
| KR890006639A (ko) | 벤조티아진 디옥사이드 유도체 | |
| MX9603348A (es) | Derivados de disulfuro de amida indano-2-mercaptoacetilica novedosos utiles como inhibidores de encefalinasa. | |
| ATE35261T1 (de) | 4-ethyl-2-hydroxy-3-methyl-2-phenylmorpholin und dessen additionssalze. | |
| ATE43594T1 (de) | 3-alkoxy-2-(n-pyrrolidino)-n-pyridyl-n-furyl(od r thienyl)-methyl-propylamine, ihre herstellung und diese enthaltende pharmazeutische mittel. | |
| ATE9892T1 (de) | Dibenzocycloheptenylidene und ihre verwendung in pharmazeutischen zusammensetzungen. |