HUP0001404A3 - Excitatory amino acid receptor modulators and pharmaceuticals containing them - Google Patents
Excitatory amino acid receptor modulators and pharmaceuticals containing themInfo
- Publication number
- HUP0001404A3 HUP0001404A3 HU0001404A HUP0001404A HUP0001404A3 HU P0001404 A3 HUP0001404 A3 HU P0001404A3 HU 0001404 A HU0001404 A HU 0001404A HU P0001404 A HUP0001404 A HU P0001404A HU P0001404 A3 HUP0001404 A3 HU P0001404A3
- Authority
- HU
- Hungary
- Prior art keywords
- amino acid
- receptor modulators
- acid receptor
- excitatory amino
- pharmaceuticals containing
- Prior art date
Links
- 102000018899 Glutamate Receptors Human genes 0.000 title 1
- 108010027915 Glutamate Receptors Proteins 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C229/50—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms being part of the same condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/52—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
- C07C247/14—Compounds containing azido groups with azido groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/32—Oximes
- C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C251/44—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups being part of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/26—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/07—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/383—Cycloaliphatic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4701197P | 1997-05-14 | 1997-05-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0001404A2 HUP0001404A2 (hu) | 2000-08-28 |
| HUP0001404A3 true HUP0001404A3 (en) | 2000-09-28 |
Family
ID=21946570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0001404A HUP0001404A3 (en) | 1997-05-14 | 1998-05-14 | Excitatory amino acid receptor modulators and pharmaceuticals containing them |
Country Status (30)
| Country | Link |
|---|---|
| US (3) | US5958960A (hu) |
| EP (1) | EP0878463B1 (hu) |
| JP (1) | JP4191263B2 (hu) |
| KR (1) | KR20010012489A (hu) |
| CN (1) | CN1125807C (hu) |
| AR (1) | AR015664A1 (hu) |
| AT (1) | ATE198190T1 (hu) |
| AU (1) | AU729632B2 (hu) |
| BR (1) | BR9808787A (hu) |
| CA (1) | CA2289472C (hu) |
| CO (1) | CO4950558A1 (hu) |
| DE (1) | DE69800430T2 (hu) |
| DK (1) | DK0878463T3 (hu) |
| EA (1) | EA199901029A1 (hu) |
| ES (1) | ES2152738T3 (hu) |
| GR (1) | GR3035156T3 (hu) |
| HU (1) | HUP0001404A3 (hu) |
| ID (1) | ID23183A (hu) |
| IL (1) | IL132894A0 (hu) |
| NO (1) | NO995480L (hu) |
| NZ (1) | NZ500954A (hu) |
| PE (1) | PE73599A1 (hu) |
| PL (1) | PL336793A1 (hu) |
| PT (1) | PT878463E (hu) |
| SI (1) | SI0878463T1 (hu) |
| SV (1) | SV1998000056A (hu) |
| TR (1) | TR199902777T2 (hu) |
| TW (1) | TW505623B (hu) |
| WO (1) | WO1998051655A1 (hu) |
| ZA (1) | ZA983930B (hu) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA983930B (en) * | 1997-05-14 | 1999-11-08 | Lilly Co Eli | Excitatory amino acid receptor modulators. |
| CN1182105C (zh) * | 1998-01-28 | 2004-12-29 | 大正制药株式会社 | 含氟氨基酸衍生物 |
| ATE269293T1 (de) * | 1998-08-31 | 2004-07-15 | Taisho Pharmaceutical Co Ltd | 6-fluoro(3.1.0)hexan-derivate |
| PE20001236A1 (es) * | 1998-11-13 | 2000-11-10 | Lilly Co Eli | Moduladores del receptor de aminoacidos excitadores |
| JP4399932B2 (ja) * | 1998-12-18 | 2010-01-20 | 大正製薬株式会社 | 中間体及びそれを用いた含フッ素アミノ酸化合物の製造方法 |
| DE60040653D1 (de) | 1999-03-25 | 2008-12-11 | Taisho Pharmaceutical Co Ltd | Carbonsäurederivate und verfahren zu ihrer herstellung |
| JP4505926B2 (ja) * | 1999-03-25 | 2010-07-21 | 大正製薬株式会社 | 新規カルボン酸誘導体及びその製造方法 |
| ATE298343T1 (de) | 1999-04-28 | 2005-07-15 | Univ Georgetown | Ligande für metabotropische glutamat-rezeptoren |
| US6528499B1 (en) * | 2000-04-27 | 2003-03-04 | Georgetown University | Ligands for metabotropic glutamate receptors and inhibitors of NAALADase |
| US6417366B2 (en) | 1999-06-24 | 2002-07-09 | Abbott Laboratories | Preparation of quinoline-substituted carbonate and carbamate derivatives |
| JP4783967B2 (ja) * | 1999-07-21 | 2011-09-28 | 大正製薬株式会社 | 含フッ素アミノ酸誘導体を有効成分とする医薬 |
| EP1246797B1 (en) * | 1999-12-08 | 2008-07-23 | Eli Lilly And Company | Cyclopentyl sulfonamide derivatives |
| US6639107B1 (en) | 1999-12-08 | 2003-10-28 | Eli Lilly And Company | Cyclopentyl sulfonamide derivatives |
| NZ526050A (en) * | 2001-01-11 | 2005-03-24 | Lilly Co Eli | Prodrugs of excitatory amino acids |
| WO2002055485A1 (en) * | 2001-01-11 | 2002-07-18 | Eli Lilly And Company | Prodrugs of excitatory amino acids |
| WO2002068380A1 (en) * | 2001-02-22 | 2002-09-06 | Eli Lilly And Company | Synthetic excitatory amino acids |
| NZ533699A (en) * | 2001-12-27 | 2006-05-26 | Taisho Pharmaceutical Co Ltd | 6-fluorobicyclo[3.1.0]hexane derivatives |
| US20040116489A1 (en) * | 2002-02-12 | 2004-06-17 | Massey Steven Marc | Synthetic excitatory amino acids |
| US20050192273A1 (en) * | 2002-04-03 | 2005-09-01 | Johnson Bryan G. | Therapy for psychoses combining an atypical antipsychotic and an mglu2/3 receptor agonist |
| NZ536459A (en) * | 2002-06-11 | 2008-03-28 | Lilly Co Eli | Prodrugs of excitatory amino acids |
| CN100582087C (zh) | 2003-06-26 | 2010-01-20 | 大正制药株式会社 | 2-氨基-双环[3.1.0]己烷-2,6-二甲酸酯衍生物 |
| WO2005000790A1 (ja) * | 2003-06-26 | 2005-01-06 | Taisho Pharmaceutical Co., Ltd. | ２－アミノビシクロ[３．１．０]ヘキサン－２，６－ジカルボン酸誘導体 |
| KR101071507B1 (ko) | 2003-06-26 | 2011-10-10 | 다이쇼 세이야꾸 가부시끼가이샤 | 2-아미노바이시클로〔3.1.0〕헥산-2,6-디카르복실산 에스테르 유도체 |
| KR101204145B1 (ko) * | 2003-11-07 | 2012-11-22 | 다이쇼 세이야꾸 가부시끼가이샤 | 비시클로〔３．１．０〕헥산 유도체의 제조 방법, 및 이에 대한 중간체 |
| US20070043100A1 (en) | 2005-08-16 | 2007-02-22 | Hagen Eric J | Novel polymorphs of azabicyclohexane |
| EP2719384B1 (en) | 2005-07-27 | 2018-08-08 | Otsuka America Pharmaceutical, Inc. | Novel 1-naphthyl-3-azabicyclo[3.1.0]hexanes:preparation and use to treat neuropsychiatric disorders |
| EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| CA2620333A1 (en) | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| EP1940389A2 (en) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| CA2625210A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| US20080045725A1 (en) * | 2006-04-28 | 2008-02-21 | Murry Jerry A | Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane |
| MX2008014320A (es) | 2006-05-09 | 2009-03-25 | Braincells Inc | Neurogenesis mediada por el receptor de 5-hidroxitriptamina. |
| AU2007249399A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| MX2009002496A (es) | 2006-09-08 | 2009-07-10 | Braincells Inc | Combinaciones que contienen un derivado de 4-acilaminopiridina. |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| US20080269348A1 (en) * | 2006-11-07 | 2008-10-30 | Phil Skolnick | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use |
| US8138377B2 (en) * | 2006-11-07 | 2012-03-20 | Dov Pharmaceutical, Inc. | Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use |
| PT3699162T (pt) | 2006-11-08 | 2022-10-11 | Molecular Insight Pharm Inc | Heterodímeros de ácido glutâmico |
| WO2008112715A2 (en) * | 2007-03-12 | 2008-09-18 | Vm Discovery Inc. | Novel agents of calcium ion channel modulators |
| EP2167083B1 (en) * | 2007-06-06 | 2015-10-28 | Euthymics Bioscience, Inc. | 1- heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments |
| US9133159B2 (en) | 2007-06-06 | 2015-09-15 | Neurovance, Inc. | 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments |
| JPWO2009142184A1 (ja) * | 2008-05-21 | 2011-09-29 | 大正製薬株式会社 | 酵素を用いたビシクロ［３．１．０］ヘキサン誘導体の製造方法 |
| EP2706057B1 (en) | 2008-12-05 | 2016-04-20 | Molecular Insight Pharmaceuticals, Inc. | Bis(imidazolyl)compounds and radionuclide complexes |
| US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| WO2010111080A2 (en) | 2009-03-27 | 2010-09-30 | Eli Lilly And Company | Optimized treatment of schizophrenia |
| BR112012000209B8 (pt) | 2009-06-15 | 2021-07-27 | Molecular Insight Pharm Inc | heterodímeros de ácido glutâmico e seus processos de preparação |
| JO2978B1 (en) | 2009-12-21 | 2016-03-15 | ايلي ليلي اند كومباني | MGLU2 aids |
| KR101554793B1 (ko) * | 2010-11-18 | 2015-09-21 | 일라이 릴리 앤드 캄파니 | mGluR 2／3 길항제로서의 4-치환된-3-벤질옥시-비시클로［3.1.0］헥산 화합물 |
| AR083845A1 (es) * | 2010-11-18 | 2013-03-27 | Lilly Co Eli | COMPUESTOS 3-FENILSULFANILMETIL-BICICLO[3.1.0]HEXANO 4-SUSTITUIDOS COMO ANTAGONISTAS DE mGluR2/3 |
| RS54888B1 (sr) | 2011-06-17 | 2016-10-31 | Lilly Co Eli | Derivati biciklo(3.1.0)heksan-2,6-dikarboksilne kiseline kao agonisti mglu2 receptora |
| EP2800471A4 (en) | 2012-01-06 | 2015-11-04 | Molecular Insight Pharm Inc | METAL COMPLEX OF POLY (CARBOXYL) AMINE CONTAINING LIGANDS HAVING AFFINITY FOR CARBON IX ANHYDRASE |
| AR089718A1 (es) | 2012-02-01 | 2014-09-10 | Lilly Co Eli | AGONISTAS DE mGlu2/3 |
| HUE035739T2 (hu) | 2013-01-14 | 2018-05-28 | Molecular Insight Pharm Inc | Triazin alapú radiogyógyszerek és radiológiai képalkotó ágensek |
| FR3050021B1 (fr) | 2016-04-06 | 2018-10-19 | Nitrates & Innovation | Ensemble de deux reservoirs prets a etre assembles par vissage pour former une cartouche d'explosif bi-composant |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5661184A (en) * | 1994-08-12 | 1997-08-26 | Eli Lilly And Company | Psychiatric agents |
| AU3364995A (en) * | 1994-08-12 | 1996-03-07 | Eli Lilly And Company | Composition and method for treating anxiety |
| PL182285B1 (pl) * | 1994-08-12 | 2001-12-31 | Lilly Co Eli | Syntetyczne aminokwasy oraz ich estry i srodki farmaceutyczne je zawierajace PL PL PL PL PL PL PL |
| AU3325095A (en) * | 1994-08-12 | 1996-03-07 | Eli Lilly And Company | Composition and method for protection against drug dependency |
| IL118727A (en) * | 1995-06-29 | 2003-01-12 | Lilly Co Eli | (-)-2-spiro-5-hydantoinbicyclo [3.1.0] hexane-6-carboxylic acid, salts thereof and use thereof for the preparation of (+)-(2) aminobicyclo [3.1.0] hexane-2,6-dicarboxylic acid |
| ZA969485B (en) | 1995-11-16 | 1998-05-12 | Lilly Co Eli | Excitatory amino acid receptor antagonists. |
| GB9605429D0 (en) * | 1995-11-16 | 1996-05-15 | Lilly Co Eli | Excitatory amino acid receptor antagonists |
| US5912248A (en) | 1995-11-16 | 1999-06-15 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
| ZA983930B (en) * | 1997-05-14 | 1999-11-08 | Lilly Co Eli | Excitatory amino acid receptor modulators. |
-
1998
- 1998-05-08 ZA ZA9803930A patent/ZA983930B/xx unknown
- 1998-05-12 CO CO98026351A patent/CO4950558A1/es unknown
- 1998-05-13 AT AT98303730T patent/ATE198190T1/de not_active IP Right Cessation
- 1998-05-13 US US09/078,337 patent/US5958960A/en not_active Expired - Lifetime
- 1998-05-13 PT PT98303730T patent/PT878463E/pt unknown
- 1998-05-13 AR ARP980102224A patent/AR015664A1/es active IP Right Grant
- 1998-05-13 SI SI9830021T patent/SI0878463T1/xx unknown
- 1998-05-13 ES ES98303730T patent/ES2152738T3/es not_active Expired - Lifetime
- 1998-05-13 EP EP98303730A patent/EP0878463B1/en not_active Expired - Lifetime
- 1998-05-13 DE DE69800430T patent/DE69800430T2/de not_active Expired - Lifetime
- 1998-05-13 DK DK98303730T patent/DK0878463T3/da active
- 1998-05-14 JP JP54954398A patent/JP4191263B2/ja not_active Expired - Fee Related
- 1998-05-14 CN CN98804992A patent/CN1125807C/zh not_active Expired - Fee Related
- 1998-05-14 ID IDW991344A patent/ID23183A/id unknown
- 1998-05-14 NZ NZ500954A patent/NZ500954A/en unknown
- 1998-05-14 AU AU73869/98A patent/AU729632B2/en not_active Ceased
- 1998-05-14 HU HU0001404A patent/HUP0001404A3/hu unknown
- 1998-05-14 IL IL13289498A patent/IL132894A0/xx unknown
- 1998-05-14 PL PL98336793A patent/PL336793A1/xx unknown
- 1998-05-14 TR TR1999/02777T patent/TR199902777T2/xx unknown
- 1998-05-14 CA CA002289472A patent/CA2289472C/en not_active Expired - Fee Related
- 1998-05-14 SV SV1998000056A patent/SV1998000056A/es unknown
- 1998-05-14 BR BR9808787-8A patent/BR9808787A/pt active Search and Examination
- 1998-05-14 TW TW087107483A patent/TW505623B/zh active
- 1998-05-14 WO PCT/US1998/009862 patent/WO1998051655A1/en not_active Application Discontinuation
- 1998-05-14 PE PE1998000370A patent/PE73599A1/es not_active Application Discontinuation
- 1998-05-14 KR KR1019997010444A patent/KR20010012489A/ko not_active Application Discontinuation
- 1998-05-14 EA EA199901029A patent/EA199901029A1/ru unknown
-
1999
- 1999-05-28 US US09/322,651 patent/US6160009A/en not_active Expired - Lifetime
- 1999-11-09 NO NO995480A patent/NO995480L/no not_active Application Discontinuation
-
2000
- 2000-08-11 US US09/637,143 patent/US6268507B1/en not_active Expired - Lifetime
- 2000-12-27 GR GR20000402844T patent/GR3035156T3/el not_active IP Right Cessation
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