HUE064694T2 - Továbbítószert tartalmazó készítmények és elõállításuk - Google Patents
Továbbítószert tartalmazó készítmények és elõállításukInfo
- Publication number
- HUE064694T2 HUE064694T2 HUE18212576A HUE18212576A HUE064694T2 HU E064694 T2 HUE064694 T2 HU E064694T2 HU E18212576 A HUE18212576 A HU E18212576A HU E18212576 A HUE18212576 A HU E18212576A HU E064694 T2 HUE064694 T2 HU E064694T2
- Authority
- HU
- Hungary
- Prior art keywords
- compositions
- preparation
- delivery agent
- delivery
- agent
- Prior art date
Links
- 229940124447 delivery agent Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/609—Amides, e.g. salicylamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12160742 | 2012-03-22 | ||
| US201361748844P | 2013-01-04 | 2013-01-04 | |
| EP13153422 | 2013-01-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE064694T2 true HUE064694T2 (hu) | 2024-04-28 |
Family
ID=49221869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE18212576A HUE064694T2 (hu) | 2012-03-22 | 2013-03-15 | Továbbítószert tartalmazó készítmények és elõállításuk |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10335369B2 (cg-RX-API-DMAC7.html) |
| EP (3) | EP2827845B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6356660B2 (cg-RX-API-DMAC7.html) |
| CN (3) | CN104203221A (cg-RX-API-DMAC7.html) |
| ES (1) | ES2965469T3 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20231613T1 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE064694T2 (cg-RX-API-DMAC7.html) |
| PL (2) | PL3542790T3 (cg-RX-API-DMAC7.html) |
| RS (2) | RS58636B1 (cg-RX-API-DMAC7.html) |
| SI (1) | SI2827845T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013139695A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2651398T (pt) | 2010-12-16 | 2018-03-09 | Novo Nordisk As | Composições sólidas compreendendo um agonista de glp-1 e um sal de ácido n-(8-(2-hidroxibenzoil)amino) caprílico |
| MY161450A (en) | 2011-04-12 | 2017-04-14 | Novo Nordisk As | Double-acylated glp-1 derivatives |
| EP2827845B1 (en) | 2012-03-22 | 2018-12-26 | Novo Nordisk A/S | Compositions comprising a delivery agent and preparation thereof |
| DK2827845T3 (en) * | 2012-03-22 | 2019-04-01 | Novo Nordisk As | COMPOSITIONS INCLUDING A PROCEDURE AND PREPARING THEREOF |
| EP4324475A1 (en) * | 2012-03-22 | 2024-02-21 | Novo Nordisk A/S | Compositions of glp-1 peptides and preparation thereof |
| CN104487056A (zh) | 2012-06-20 | 2015-04-01 | 诺和诺德A/S(股份有限公司) | 包含肽和递送剂的片剂制剂 |
| PL2991671T3 (pl) | 2013-05-02 | 2019-01-31 | Novo Nordisk As | Doustne dawkowanie związków glp-1 |
| CN104173313B (zh) * | 2014-08-25 | 2017-05-17 | 杭州朱养心药业有限公司 | 利伐沙班片剂药物组合物 |
| CN107427469B (zh) | 2015-01-12 | 2021-01-26 | 安特里斯生物制药公司 | 固体口服剂型 |
| CN108883073B (zh) * | 2016-12-30 | 2021-10-08 | 江苏恒瑞医药股份有限公司 | 一种glp-1类似物的药物组合物及其制备方法 |
| TWI797133B (zh) | 2017-06-09 | 2023-04-01 | 丹麥商諾佛 儂迪克股份有限公司 | 用於經口投予的固體組成物 |
| JP6898518B2 (ja) | 2018-02-02 | 2021-07-07 | ノヴォ ノルディスク アー/エス | Glp−1アゴニスト、n−(8−(2−ヒドロキシベンゾイル)アミノ)カプリル酸の塩及び滑沢剤を含む固形組成物 |
| TWI829687B (zh) | 2018-05-07 | 2024-01-21 | 丹麥商諾佛 儂迪克股份有限公司 | 包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物 |
| CN113329810A (zh) * | 2019-01-24 | 2021-08-31 | 诺和诺德股份有限公司 | 辊压机和使用辊压机的干法制粒方法 |
| KR20220046565A (ko) * | 2019-08-07 | 2022-04-14 | 노보 노르디스크 에이/에스 | Egf(a) 유도체 및 n-(8-(2-하이드록시벤조일)아미노)카프릴산의 염을 포함하는 고형 조성물 |
| EP4025192B1 (en) | 2019-09-02 | 2025-12-03 | Novo Nordisk A/S | Process for producing a tablet comprising glp-1 peptides |
| WO2021043971A1 (en) | 2019-09-06 | 2021-03-11 | Novo Nordisk A/S | Method and equipment for fractionation of granules for use in pharmaceutical compositions |
| EP4054536A1 (en) | 2019-11-07 | 2022-09-14 | Novo Nordisk A/S | Solid compositions comprising a glp-1 agonist, an sglt2 inhibitor and a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid |
| CN115461044B (zh) * | 2020-04-29 | 2025-06-10 | 诺和诺德股份有限公司 | 包含glp-1激动剂和组氨酸的固体组合物 |
| CN111517980B (zh) * | 2020-05-14 | 2021-02-09 | 台州浦凯医药科技有限公司 | N-[8-(2-羟基苯甲酰基)氨基]辛酸一钾晶型化合物、制备方法及用途 |
| IL299701A (en) * | 2020-07-22 | 2023-03-01 | Novo Nordisk As | GLP-1 and GIP receptor co-agonists suitable for oral administration |
| TW202214679A (zh) * | 2020-07-22 | 2022-04-16 | 丹麥商諾佛 儂迪克股份有限公司 | Glp-1及gip受體共促效劑 |
| CN113117050B (zh) * | 2021-05-06 | 2022-04-26 | 合肥天汇孵化科技有限公司 | 多肽组合物及其用途 |
| IL308280A (en) | 2021-05-07 | 2024-01-01 | Lilly Co Eli | Tablet worn out |
| JP2024525377A (ja) | 2021-07-15 | 2024-07-12 | ノヴォ ノルディスク アー/エス | N-(8-(2-ヒドロキシベンゾイル)アミノ)カプリル酸の塩を含む錠剤 |
| AU2022401780A1 (en) * | 2021-12-01 | 2024-07-04 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Pharmaceutical composition of glp-1 and gip receptor dual agonist and use thereof |
| TW202330584A (zh) | 2022-01-20 | 2023-08-01 | 丹麥商諾佛 儂迪克股份有限公司 | 前藥及其用途 |
| CN114984191B (zh) * | 2022-07-04 | 2022-10-25 | 北京惠之衡生物科技有限公司 | 一种多肽类药物口服递送组合物 |
| TW202421645A (zh) | 2022-11-25 | 2024-06-01 | 丹麥商諾佛 儂迪克股份有限公司 | 如glp—1之肽治療劑的口服投與 |
Family Cites Families (84)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4609675A (en) | 1984-08-17 | 1986-09-02 | The Upjohn Company | Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing |
| US4918098A (en) | 1986-03-12 | 1990-04-17 | American Cyanamid Company | Macrolide compounds |
| DK39892D0 (da) | 1992-03-25 | 1992-03-25 | Bernard Thorens | Peptid |
| US5869602A (en) | 1995-03-17 | 1999-02-09 | Novo Nordisk A/S | Peptide derivatives |
| US5650386A (en) | 1995-03-31 | 1997-07-22 | Emisphere Technologies, Inc. | Compositions for oral delivery of active agents |
| US5866536A (en) | 1995-03-31 | 1999-02-02 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| SE9600070D0 (sv) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
| DE69737479T4 (de) | 1996-08-30 | 2010-05-06 | Novo Nordisk A/S | Glp-1 derivate |
| US5773647A (en) | 1997-02-07 | 1998-06-30 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| WO1999043707A1 (en) | 1998-02-27 | 1999-09-02 | Novo Nordisk A/S | N-terminally modified glp-1 derivatives |
| EP1056775B1 (en) | 1998-02-27 | 2010-04-28 | Novo Nordisk A/S | Glp-1 derivatives of glp-1 and exendin with protracted profile of action |
| EP1061946B1 (en) | 1998-02-27 | 2004-04-28 | Novo Nordisk A/S | Glp-1 derivatives with helix-content exceeding 25 %, forming partially structured micellar-like aggregates |
| ATE466027T1 (de) | 1998-02-27 | 2010-05-15 | Novo Nordisk As | Abkömmlinge von glp-1 analogen |
| SE9802080D0 (sv) | 1998-06-11 | 1998-06-11 | Hellstroem | Pharmaceutical composition for the treatment of functional dyspepsia and/or irritable bowel syndrome and new use of substances therein |
| AU3357800A (en) | 1999-02-05 | 2000-08-25 | Emisphere Technologies, Inc. | Method of preparing alkylated salicylamides |
| WO2000048589A1 (en) | 1999-02-22 | 2000-08-24 | Emisphere Holdings, Inc. | Solid oral dosage form containing heparin or a heparinoid in combination with a carrier |
| JP2002537321A (ja) | 1999-02-22 | 2002-11-05 | エラン コーポレイション ピーエルスィー | 促進剤を含む固体経口剤形 |
| US7658938B2 (en) | 1999-02-22 | 2010-02-09 | Merrion Reasearch III Limited | Solid oral dosage form containing an enhancer |
| GB9923436D0 (en) | 1999-10-04 | 1999-12-08 | American Home Prod | Pharmaceutical compositions |
| US6793934B1 (en) | 1999-12-08 | 2004-09-21 | Shire Laboratories, Inc. | Solid oral dosage form |
| WO2001092206A1 (en) | 2000-06-02 | 2001-12-06 | Emisphere Technologies, Inc. | Method of preparing salicylamides |
| US7049283B2 (en) | 2000-12-06 | 2006-05-23 | Novartis Ag | Pharmaceutical compositions for the oral delivery of pharmacologically active agents |
| MXPA03008837A (es) | 2001-03-27 | 2004-05-05 | Ranbaxy Lab Ltd | Una composicion farmaceutica estable de pravastatina. |
| PL366728A1 (en) | 2001-05-15 | 2005-02-07 | Warner-Lambert Company Llc | Compaction process for manufacture of sodium phenytoin dosage form |
| US20030068356A1 (en) | 2001-07-10 | 2003-04-10 | Pather S. Indiran | Sequential drug delivery systems |
| AU2002352974A1 (en) | 2001-11-29 | 2003-06-10 | Emisphere Technologies, Inc. | Formulations for oral administration of cromolyn sodium |
| WO2003063838A1 (en) | 2002-02-01 | 2003-08-07 | Pfizer Products Inc. | Dry granulated formulations of azithromycin |
| JP4417113B2 (ja) | 2002-02-20 | 2010-02-17 | エミスフェアー・テクノロジーズ・インク | Glp−1分子の投与方法 |
| JP2004131398A (ja) | 2002-10-08 | 2004-04-30 | Taihei Chemical Industrial Co Ltd | 錠剤用滑沢剤 |
| CA2525168A1 (en) | 2003-05-14 | 2004-12-02 | Emisphere Technologies, Inc. | Compositions for delivering peptide yy and pyy agonists |
| PL1651248T3 (pl) | 2003-07-11 | 2010-02-26 | Novartis Ag | Doustnie dawkowana kompozycja farmaceutyczna zawierająca środek dostarczający w postaci mikronizowanej |
| JP4949838B2 (ja) | 2003-09-19 | 2012-06-13 | ノヴォ ノルディスク アー/エス | 新規glp−1誘導体 |
| EP1704165B1 (en) | 2003-12-18 | 2010-03-17 | Novo Nordisk A/S | Glp-1 compounds |
| AU2004298425A1 (en) | 2003-12-18 | 2005-06-30 | Novo Nordisk A/S | Novel GLP-1 analogues linked to albumin-like agents |
| US20060286129A1 (en) | 2003-12-19 | 2006-12-21 | Emisphere Technologies, Inc. | Oral GLP-1 formulations |
| WO2005099672A1 (en) | 2004-04-13 | 2005-10-27 | Ranbaxy Laboratories Limited | A modified release pharmaceutical formulation comprising amoxicillin and clavulanate |
| JP2007536268A (ja) * | 2004-05-06 | 2007-12-13 | エミスフェアー・テクノロジーズ・インク | 固体剤形の湿性ヘパリン |
| CN102040536B (zh) | 2004-05-06 | 2013-06-19 | 爱密斯菲尔科技公司 | N-[8-(2-羟基苯甲酰基)氨基]辛酸一钠的晶体的多晶 |
| EP1756039B1 (en) | 2004-05-14 | 2012-10-17 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| CN1767818A (zh) | 2004-05-31 | 2006-05-03 | 三亚药品株式会社 | 含β-内酰胺抗生素的分散片剂及其制备方法 |
| CN101010339B (zh) | 2004-07-02 | 2011-11-09 | 布里斯托尔-迈尔斯斯奎布公司 | 人类胰高血糖素样肽-1调节剂及它们在治疗糖尿病及相关病况中的用途 |
| ES2564167T3 (es) | 2004-07-08 | 2016-03-18 | Novo Nordisk A/S | Conjugados de polipéptidos de acción prolongada que contienen una fracción tetrazol |
| EP1781257B1 (en) | 2004-08-13 | 2018-12-19 | Emisphere Technologies, Inc. | Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent |
| WO2006037811A2 (en) | 2004-10-07 | 2006-04-13 | Novo Nordisk A/S | Protracted exendin-4 compounds |
| US7893017B2 (en) | 2004-10-07 | 2011-02-22 | Novo Nordisk A/S | Protracted GLP-1 compounds |
| NZ555120A (en) | 2004-12-03 | 2009-11-27 | Merck & Co Inc | Pharmaceutical formulation of carboxamide HIV integrase inhibitors containing a release rate controlling composition |
| EP1843755B1 (en) | 2005-02-01 | 2015-04-01 | Emisphere Technologies, Inc. | Gastric retention and controlled release delivery system |
| TWI362392B (en) | 2005-03-18 | 2012-04-21 | Novo Nordisk As | Acylated glp-1 compounds |
| KR20070120112A (ko) | 2005-03-18 | 2007-12-21 | 노보 노르디스크 에이/에스 | 연장형 glp-1 화합물 |
| US20080260818A1 (en) | 2005-03-28 | 2008-10-23 | Dexcel Pharma Technologies Ltd. | Controlled Absorption of Statins in the Intestine |
| US20070049557A1 (en) | 2005-08-24 | 2007-03-01 | Hashim Ahmed | Solid pharmaceutical dosage forms comprising bisphosphonates and modified amino acid carriers |
| KR101432313B1 (ko) | 2005-11-17 | 2014-08-20 | 노파르티스 아게 | 약제학적 조성물 |
| BRPI0710503A2 (pt) | 2006-04-07 | 2011-08-16 | Merrion Res Iii Ltd | uso de uma composição farmacêutica, composição farmacêutica, e, forma de dosagem oral |
| US8927015B2 (en) | 2006-04-12 | 2015-01-06 | Emisphere Technologies, Inc. | Formulations for delivering insulin |
| JP2009539862A (ja) | 2006-06-09 | 2009-11-19 | メリオン リサーチ Iii リミテッド | 強化剤を含む固体経口投与剤形 |
| EP2040718B1 (en) * | 2006-06-28 | 2017-12-27 | Emisphere Technologies, Inc. | Gallium nitrate formulations |
| ES2296529B1 (es) | 2006-08-07 | 2009-04-01 | Laboratorios Farmaceuticos Rovi, S.A. | Composicion farmaceutica con promotores de absorcion. |
| EP2057189B1 (en) | 2006-08-25 | 2013-03-06 | Novo Nordisk A/S | Acylated exendin-4 compounds |
| JP5021033B2 (ja) | 2006-09-07 | 2012-09-05 | エフ.ホフマン−ラ ロシュ アーゲー | Snac(サルカプロザートナトリウム)の製造法 |
| AR062925A1 (es) | 2006-09-22 | 2008-12-17 | Novartis Ag | Metodo para fabricar tabletas que contienen agentes farmacologicamente activos |
| WO2008070547A1 (en) | 2006-12-01 | 2008-06-12 | Emisphere Technologies Inc. | Improved acyclovir formulations |
| PL2131810T3 (pl) | 2007-03-02 | 2011-09-30 | Novartis Ag | Podawanie doustne kalcytoniny |
| US20110183889A1 (en) | 2007-08-29 | 2011-07-28 | The Regents Of The University Of California | Salicylanilide modified peptides for use as oral therapeutics |
| WO2009030771A1 (en) | 2007-09-05 | 2009-03-12 | Novo Nordisk A/S | Peptides derivatized with a-b-c-d- and their therapeutical use |
| CN101842386A (zh) | 2007-09-05 | 2010-09-22 | 诺沃-诺迪斯克有限公司 | 截短的glp-1衍生物和它们的治疗用途 |
| WO2009030738A1 (en) | 2007-09-05 | 2009-03-12 | Novo Nordisk A/S | Glucagon-like peptide-1 derivatives and their pharmaceutical use |
| MX2010003979A (es) | 2007-10-16 | 2010-06-02 | Biocon Ltd | Composicion farmaceutica oralmente administrable y proceso para su preparacion. |
| MX2010004716A (es) | 2007-11-02 | 2010-12-17 | Emisphere Tech Inc | Metodo para tratar la deficiencia de vitamina b12. |
| US20090124639A1 (en) * | 2007-11-06 | 2009-05-14 | Emisphere Technologies Inc. | valacyclovir formulations |
| US20100317057A1 (en) * | 2007-12-28 | 2010-12-16 | Novo Nordisk A/S | Semi-recombinant preparation of glp-1 analogues |
| NZ591497A (en) * | 2008-08-18 | 2012-11-30 | Entera Bio Ltd | A compositions comprising a protein, a protease inhibitor and N-(8-[2-hydroxybenzoyl]amino)caprylate (SNAC) or N-(10[2-hydroxybenzoyl]amino)decanoate (SNAD) for diabetes mellitus treatment |
| CN117547538A (zh) | 2009-02-13 | 2024-02-13 | 勃林格殷格翰国际有限公司 | 包含dpp-4抑制剂(利格列汀)任选地组合其它抗糖尿病药的抗糖尿病药物 |
| AU2010339907A1 (en) | 2009-12-16 | 2012-07-05 | Nod Pharmaceuticals, Inc. | Compositions and methods for oral drug delivery |
| US20110182985A1 (en) | 2010-01-28 | 2011-07-28 | Coughlan David C | Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof |
| WO2011109787A1 (en) | 2010-03-05 | 2011-09-09 | Conjuchem, Llc | Methods of administering insulinotropic peptides |
| WO2011116139A2 (en) | 2010-03-16 | 2011-09-22 | Chiasma Inc. | Improved pharmaceutical compositions and methods of delivery |
| AR081760A1 (es) | 2010-04-07 | 2012-10-17 | Vertex Pharma | Una composicion farmaceutica para administracion oral que comprende acido 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-il)ciclopropancarboxamido)-3-metilpiridin-2-il)benzoico, un metodo para producir la misma, una tableta y una forma unitaria de dosificacion oral que la comprende y el uso de la misma para la fabricacion de un medicamento |
| CN107961377B (zh) | 2010-05-05 | 2022-11-22 | 勃林格殷格翰国际有限公司 | 组合疗法 |
| DE202010015867U1 (de) | 2010-11-25 | 2011-05-05 | Buchhalter, Thomas | Elektromechanische Halterung zur Aufnahme von Navigations- und Kommunikationsgeräte im KFZ |
| PT2651398T (pt) | 2010-12-16 | 2018-03-09 | Novo Nordisk As | Composições sólidas compreendendo um agonista de glp-1 e um sal de ácido n-(8-(2-hidroxibenzoil)amino) caprílico |
| EP4324475A1 (en) | 2012-03-22 | 2024-02-21 | Novo Nordisk A/S | Compositions of glp-1 peptides and preparation thereof |
| EP2827845B1 (en) | 2012-03-22 | 2018-12-26 | Novo Nordisk A/S | Compositions comprising a delivery agent and preparation thereof |
| CN104487056A (zh) | 2012-06-20 | 2015-04-01 | 诺和诺德A/S(股份有限公司) | 包含肽和递送剂的片剂制剂 |
| PL2991671T3 (pl) | 2013-05-02 | 2019-01-31 | Novo Nordisk As | Doustne dawkowanie związków glp-1 |
-
2013
- 2013-03-15 EP EP13709232.6A patent/EP2827845B1/en not_active Revoked
- 2013-03-15 EP EP18212576.5A patent/EP3542790B1/en active Active
- 2013-03-15 CN CN201380015235.1A patent/CN104203221A/zh active Pending
- 2013-03-15 EP EP23195317.5A patent/EP4331667A3/en active Pending
- 2013-03-15 PL PL18212576.5T patent/PL3542790T3/pl unknown
- 2013-03-15 RS RS20190386A patent/RS58636B1/sr unknown
- 2013-03-15 SI SI201331386T patent/SI2827845T1/sl unknown
- 2013-03-15 HU HUE18212576A patent/HUE064694T2/hu unknown
- 2013-03-15 ES ES18212576T patent/ES2965469T3/es active Active
- 2013-03-15 JP JP2015500854A patent/JP6356660B2/ja active Active
- 2013-03-15 US US14/386,218 patent/US10335369B2/en active Active
- 2013-03-15 CN CN202010243610.XA patent/CN111494324B/zh active Active
- 2013-03-15 HR HRP20231613TT patent/HRP20231613T1/hr unknown
- 2013-03-15 PL PL13709232T patent/PL2827845T3/pl unknown
- 2013-03-15 WO PCT/EP2013/055363 patent/WO2013139695A1/en not_active Ceased
- 2013-03-15 RS RS20231190A patent/RS64942B1/sr unknown
- 2013-03-15 CN CN202010243609.7A patent/CN111494323B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN104203221A (zh) | 2014-12-10 |
| EP2827845B1 (en) | 2018-12-26 |
| CN111494324B (zh) | 2023-05-16 |
| US20150031606A1 (en) | 2015-01-29 |
| EP4331667A3 (en) | 2024-05-08 |
| JP2015515459A (ja) | 2015-05-28 |
| WO2013139695A1 (en) | 2013-09-26 |
| EP2827845A1 (en) | 2015-01-28 |
| EP3542790A1 (en) | 2019-09-25 |
| PL3542790T3 (pl) | 2024-02-26 |
| PL2827845T3 (pl) | 2019-06-28 |
| JP6356660B2 (ja) | 2018-07-11 |
| ES2965469T3 (es) | 2024-04-15 |
| RS58636B1 (sr) | 2019-05-31 |
| RS64942B1 (sr) | 2024-01-31 |
| CN111494323A (zh) | 2020-08-07 |
| US10335369B2 (en) | 2019-07-02 |
| CN111494324A (zh) | 2020-08-07 |
| EP3542790C0 (en) | 2023-09-13 |
| SI2827845T1 (sl) | 2019-04-30 |
| HRP20231613T1 (hr) | 2024-03-15 |
| EP4331667A2 (en) | 2024-03-06 |
| CN111494323B (zh) | 2023-03-28 |
| EP3542790B1 (en) | 2023-09-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SI2827845T1 (sl) | Sestavki, ki obsegajo dostavno sredstvo in njihova priprava | |
| IL286348A (en) | Pharmaceutical preparations that include allopregnanolone | |
| IL253870B (en) | Certain amino-pyrimidines and pharmaceutical preparations containing them | |
| ZA201703992B (en) | Inhalable pharmaceutical compositions | |
| IL236268B (en) | Preparations for mucosal administration and their uses | |
| IL236358B (en) | Medicinal preparations containing hormone replacements and their use | |
| IL236024A (en) | The history of benzimidazole-proline and its pharmaceutical preparations | |
| ZA201402988B (en) | Dermal Delivery Compositions and Methods | |
| PT2827845T (pt) | Composições compreendendo um agente de entrega e sua preparação | |
| IL252566B (en) | Pharmacy preparations and methods | |
| SG10202112138QA (en) | Compositions comprising peg and sulphate | |
| EP2753341A4 (en) | ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | |
| SG11201404123XA (en) | Medicament delivery devices | |
| IL233825A (en) | H1-indazole-3-carboxamide compounds, preparations containing them and their use in the preparation of medicines | |
| EP2685993A4 (en) | PHARMACEUTICAL COMPOSITIONS AND TOPICAL USE THEREOF | |
| IL235830A0 (en) | New dosage and formulation | |
| EP2668044A4 (en) | COMPOSITIONS AND THEIR USE | |
| EP2874641A4 (en) | COMPOSITIONS INCREASING THE GLUTATHION RATE AND USES THEREOF | |
| PL2908837T3 (pl) | Kompozycje do dostarczania leku | |
| ZA201307837B (en) | Compositions comprising antibacterial agent and tazobactam | |
| IL226554A (en) | Medicinal preparations containing alisporiovir | |
| ZA201504512B (en) | Pharmaceutical composition comprising desloratadine and prednisolone and use thereof | |
| GB201208315D0 (en) | Pharmaceutical methods and compositions | |
| GB201110598D0 (en) | Pharmaceutical compositions and devices | |
| GB201219884D0 (en) | New composition and preparation thereof |