HUE064531T2 - Szubsztituált naftiridinon vegyületek mint T-sejt aktivátorok - Google Patents
Szubsztituált naftiridinon vegyületek mint T-sejt aktivátorokInfo
- Publication number
- HUE064531T2 HUE064531T2 HUE19744923A HUE19744923A HUE064531T2 HU E064531 T2 HUE064531 T2 HU E064531T2 HU E19744923 A HUE19744923 A HU E19744923A HU E19744923 A HUE19744923 A HU E19744923A HU E064531 T2 HUE064531 T2 HU E064531T2
- Authority
- HU
- Hungary
- Prior art keywords
- cell activators
- naphthyridine compounds
- substituted naphthyridine
- substituted
- compounds
- Prior art date
Links
- 229940126530 T cell activator Drugs 0.000 title 1
- 150000005054 naphthyridines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862690439P | 2018-06-27 | 2018-06-27 | |
| US201962840459P | 2019-04-30 | 2019-04-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE064531T2 true HUE064531T2 (hu) | 2024-04-28 |
Family
ID=67439335
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE19744923A HUE064531T2 (hu) | 2018-06-27 | 2019-06-26 | Szubsztituált naftiridinon vegyületek mint T-sejt aktivátorok |
Country Status (28)
| Country | Link |
|---|---|
| US (3) | US10669272B2 (https=) |
| EP (1) | EP3814348B9 (https=) |
| JP (1) | JP7432532B2 (https=) |
| KR (1) | KR102767739B1 (https=) |
| CN (1) | CN112654621B (https=) |
| AU (1) | AU2019291794B2 (https=) |
| BR (1) | BR112020026681A2 (https=) |
| CA (1) | CA3104654A1 (https=) |
| CL (1) | CL2020003260A1 (https=) |
| CY (1) | CY1126280T1 (https=) |
| DK (1) | DK3814348T3 (https=) |
| ES (1) | ES2960754T3 (https=) |
| FI (1) | FI3814348T3 (https=) |
| HR (1) | HRP20231253T1 (https=) |
| HU (1) | HUE064531T2 (https=) |
| IL (1) | IL279728B2 (https=) |
| LT (1) | LT3814348T (https=) |
| MX (1) | MX2020013817A (https=) |
| PE (1) | PE20210469A1 (https=) |
| PL (1) | PL3814348T3 (https=) |
| PT (1) | PT3814348T (https=) |
| RS (1) | RS64641B1 (https=) |
| SG (1) | SG11202012972YA (https=) |
| SI (1) | SI3814348T1 (https=) |
| SM (1) | SMT202300466T1 (https=) |
| TW (1) | TW202019924A (https=) |
| WO (1) | WO2020006018A1 (https=) |
| ZA (1) | ZA202100555B (https=) |
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| CN111471059B (zh) * | 2019-01-23 | 2022-12-02 | 药捷安康(南京)科技股份有限公司 | Pde9抑制剂及其用途 |
| AU2020266529B2 (en) | 2019-04-29 | 2026-01-29 | Solent Therapeutics, Llc | 3-amino-4H-benzo[E][1,2,4]thiadiazine 1,1-dioxide derivatives as inhibitors of MRGX2 |
| AR119821A1 (es) | 2019-08-28 | 2022-01-12 | Bristol Myers Squibb Co | Compuestos de piridopirimidinonilo sustituidos útiles como activadores de células t |
| CN115210225A (zh) | 2019-11-28 | 2022-10-18 | 拜耳公司 | 取代的氨基喹诺酮类作为免疫激活的dgkalpha抑制剂 |
| US20230064809A1 (en) | 2019-11-28 | 2023-03-02 | Bayer Aktiengesellschaft | Substituted aminoquinolones as dgkalpha inhibitors for immune activation |
| KR20220122637A (ko) | 2019-11-28 | 2022-09-02 | 바이엘 악티엔게젤샤프트 | 면역 활성화를 위한 dgk알파 억제제로서의 치환된 아미노퀴놀론 |
| BR112022009631A2 (pt) * | 2019-12-19 | 2022-08-09 | Bristol Myers Squibb Co | Combinações de inibidores de dgk e antagonistas do ponto de checagem |
| KR20220119456A (ko) * | 2019-12-23 | 2022-08-29 | 브리스톨-마이어스 스큅 컴퍼니 | T 세포 활성화제로서 유용한 치환된 퀴놀리노닐 피페라진 화합물 |
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2019
- 2019-06-26 CN CN201980055715.8A patent/CN112654621B/zh active Active
- 2019-06-26 HU HUE19744923A patent/HUE064531T2/hu unknown
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2020
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2021
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2023
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