HUE041981T2 - Eljárások antipszichotikum által kiváltott súlygyarapodás kezelésére - Google Patents
Eljárások antipszichotikum által kiváltott súlygyarapodás kezeléséreInfo
- Publication number
- HUE041981T2 HUE041981T2 HUE11820517A HUE11820517A HUE041981T2 HU E041981 T2 HUE041981 T2 HU E041981T2 HU E11820517 A HUE11820517 A HU E11820517A HU E11820517 A HUE11820517 A HU E11820517A HU E041981 T2 HUE041981 T2 HU E041981T2
- Authority
- HU
- Hungary
- Prior art keywords
- methods
- weight gain
- induced weight
- antipsychotic
- treating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37612010P | 2010-08-23 | 2010-08-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE041981T2 true HUE041981T2 (hu) | 2019-06-28 |
Family
ID=45723770
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE11820517A HUE041981T2 (hu) | 2010-08-23 | 2011-08-23 | Eljárások antipszichotikum által kiváltott súlygyarapodás kezelésére |
Country Status (19)
| Country | Link |
|---|---|
| US (10) | US8778960B2 (hu) |
| EP (3) | EP3446565B1 (hu) |
| JP (1) | JP5684388B2 (hu) |
| AU (4) | AU2011293502B2 (hu) |
| CA (1) | CA2807965C (hu) |
| CY (1) | CY1121128T1 (hu) |
| DK (2) | DK2608670T3 (hu) |
| ES (1) | ES2705726T3 (hu) |
| FI (1) | FI3446565T3 (hu) |
| HR (2) | HRP20240109T1 (hu) |
| HU (1) | HUE041981T2 (hu) |
| LT (2) | LT2608670T (hu) |
| NZ (1) | NZ606730A (hu) |
| PL (2) | PL2608670T3 (hu) |
| PT (2) | PT2608670T (hu) |
| RS (2) | RS65091B1 (hu) |
| SI (2) | SI2608670T1 (hu) |
| TR (1) | TR201900097T4 (hu) |
| WO (1) | WO2012027359A1 (hu) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010151689A1 (en) * | 2009-06-25 | 2010-12-29 | Alkermes, Inc. | Heterocyclic compounds for the treatment of neurological and psychological disorders |
| WO2011068594A1 (en) | 2009-12-04 | 2011-06-09 | Alkermes, Inc. | Morphinan derivatives for the treatment of drug overdose |
| TR201900097T4 (tr) | 2010-08-23 | 2019-02-21 | Alkermes Pharma Ireland Ltd | Anti̇psi̇koti̇k i̇le i̇ndüklenen ki̇lo artişini tedavi̇ etmeye yöneli̇k yöntemler. |
| US9211293B2 (en) | 2011-12-15 | 2015-12-15 | Alkermes Pharma Ireland Limited | Opioid agonist antagonist combinations |
| NZ631018A (en) | 2013-05-24 | 2017-12-22 | Alkermes Pharma Ireland Ltd | Morphan and morphinan analogues, and methods of use |
| WO2014190271A2 (en) | 2013-05-24 | 2014-11-27 | Alkermes Pharma Ireland Limted | Methods for treating depressive symptoms |
| WO2020006367A1 (en) * | 2018-06-29 | 2020-01-02 | Tufts Medical Center, Inc. | Methods and compositions for preventing and treating metabolic syndrome induced by antipsychotic treatment and related diseases and conditions |
| EP4243768A1 (en) * | 2020-11-12 | 2023-09-20 | Alkermes Pharma Ireland Limited | Immediate release multilayer tablet |
| WO2023105103A1 (es) | 2022-06-17 | 2023-06-15 | Mesoestetic Pharma Group, S.L | Composición cosmética sinérgica despigmentante de la piel |
Family Cites Families (87)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB874217A (en) | 1958-10-30 | 1961-08-02 | Albert Boehringer | Normorphine derivatives |
| BE634402A (fr) | 1962-07-02 | 1964-01-02 | British Drug Houses Ltd | Dérivés de l'hydrophénanthrène et leurs procédés de préparation |
| GB981046A (en) | 1962-07-02 | 1965-01-20 | British Drug Houses Ltd | Hexahydro-4ah-8,9c-iminoethano phenanthro-[4,5-b,c,d]-furan derivatives |
| US3332950A (en) | 1963-03-23 | 1967-07-25 | Endo Lab | 14-hydroxydihydronormorphinone derivatives |
| US3539573A (en) | 1967-03-22 | 1970-11-10 | Jean Schmutz | 11-basic substituted dibenzodiazepines and dibenzothiazepines |
| CH581624A5 (hu) | 1970-08-14 | 1976-11-15 | Sumitomo Chemical Co | |
| US3856795A (en) | 1972-04-25 | 1974-12-24 | American Home Prod | Process for preparation of secondary amines from tertiary amines |
| DE2254298A1 (de) | 1972-11-06 | 1974-05-16 | Boehringer Sohn Ingelheim | Neue (heteroarylmethyl)-normorphine, deren saeureadditionssalze, verfahren zu deren herstellung sowie deren verwendung als arzneimittel |
| US3957793A (en) | 1974-09-20 | 1976-05-18 | Sterling Drug Inc. | Hydroxyiminobenzazocines |
| US4032529A (en) | 1974-09-20 | 1977-06-28 | Sterling Drug Inc. | Aminomethanobenzazocine intermediates |
| US4127577A (en) | 1975-11-24 | 1978-11-28 | Sterling Drug Inc. | Aminomethanobenzazocine process |
| US4205171A (en) | 1976-01-12 | 1980-05-27 | Sterling Drug Inc. | Aminomethanobenzazocines and nitromethanobenzazocines |
| US4161597A (en) | 1976-12-20 | 1979-07-17 | Research Corporation | N-alkyl-14-hydroxymorphinans and derivatives |
| US4100228A (en) | 1977-04-04 | 1978-07-11 | The Dow Chemical Company | Transparent impact styrene polymer structure |
| US4176186A (en) | 1978-07-28 | 1979-11-27 | Boehringer Ingelheim Gmbh | Quaternary derivatives of noroxymorphone which relieve intestinal immobility |
| US4373139A (en) | 1979-04-30 | 1983-02-08 | Motorola, Inc. | Detectors |
| US4464378A (en) | 1981-04-28 | 1984-08-07 | University Of Kentucky Research Foundation | Method of administering narcotic antagonists and analgesics and novel dosage forms containing same |
| FR2514644A1 (fr) | 1981-10-19 | 1983-04-22 | Sanofi Sa | Composition pharmaceutique a action antagoniste peripherique des opiaces |
| DE3220831A1 (de) | 1982-06-03 | 1983-12-08 | Boehringer Ingelheim KG, 6507 Ingelheim | N-(2-methoxyethyl)-noroxymorphon, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung |
| US4451470A (en) | 1982-07-06 | 1984-05-29 | E. I. Du Pont De Nemours And Company | Analgesic, antagonist, and/or anorectic 14-fluoromorphinans |
| US4804663A (en) | 1985-03-27 | 1989-02-14 | Janssen Pharmaceutica N.V. | 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles |
| GB8607684D0 (en) | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
| US4649200A (en) | 1986-05-08 | 1987-03-10 | Regents Of The University Of Minnesota | Substituted pyrroles with opioid receptor activity |
| US4939264A (en) | 1986-07-14 | 1990-07-03 | Abbott Laboratories | Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies |
| US4929622A (en) | 1987-09-24 | 1990-05-29 | Hoechst-Roussel Pharmaceuticals, Inc. | 2,6-Methanopyrrolo-3-benzazocines |
| US4831031A (en) | 1988-01-22 | 1989-05-16 | Pfizer Inc. | Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity |
| US5006528A (en) | 1988-10-31 | 1991-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| US5229382A (en) | 1990-04-25 | 1993-07-20 | Lilly Industries Limited | 2-methyl-thieno-benzodiazepine |
| US5258386A (en) | 1991-06-05 | 1993-11-02 | The United States Of America As Represented By The Secretary Of The Army | (+)-3-substituted-N alkylmorphinans, synthesis and use as anticonvulsant and neuroprotective agents |
| US5607941A (en) | 1992-06-26 | 1997-03-04 | Boehringer Ingelheim Kg | Useful for treating neurodegenerative diseases |
| SE9103745D0 (sv) | 1991-12-18 | 1991-12-18 | Wikstroem Haakan | Aryl-triflates and related compounds |
| JPH05231100A (ja) | 1992-02-25 | 1993-09-07 | Hazama Gumi Ltd | トンネル用通気仕切り |
| US5312925A (en) | 1992-09-01 | 1994-05-17 | Pfizer Inc. | Monohydrate of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one-hydrochloride |
| EP0632041A1 (en) | 1993-07-01 | 1995-01-04 | Katholieke Universiteit Nijmegen | New morphine derivatives having improved analgesic and narcotic properties |
| EP1649850A1 (en) | 1993-11-19 | 2006-04-26 | Alkermes Controlled Therapeutics Inc. II | Preparation of biodegradable microparticles containing a biologically active agent |
| US5650173A (en) | 1993-11-19 | 1997-07-22 | Alkermes Controlled Therapeutics Inc. Ii | Preparation of biodegradable microparticles containing a biologically active agent |
| EG23659A (en) | 1995-03-24 | 2007-03-26 | Lilly Co Eli | Process and crystal forms of methyl-thieno-benzodiazepine |
| EP0880526B1 (en) | 1996-01-10 | 2002-12-18 | GlaxoSmithKline S.p.A. | Heterocycle-condensed morphinoid derivatives (ii) |
| GB9616253D0 (en) | 1996-08-01 | 1996-09-11 | Johnson Matthey Plc | Preparation of narcotic analgesics |
| ES2121553B1 (es) | 1996-12-23 | 1999-06-16 | Univ Santiago Compostela | Nuevos endoperoxidos morfinicos funcionalizados en posiciones c-6 y c-14 del anillo c y procedimiento para su obtencion. |
| GB9709972D0 (en) | 1997-05-19 | 1997-07-09 | Pfizer Ltd | Tetrazoles |
| GB9912411D0 (en) | 1999-05-28 | 1999-07-28 | Pfizer Ltd | Compounds useful in therapy |
| WO2001012197A1 (en) | 1999-08-13 | 2001-02-22 | Southern Research Institute | Pyridomorphinans, thienomoprhinans and use thereof |
| US6495166B1 (en) | 1999-11-12 | 2002-12-17 | Alkermes Controlled Therapeutics Inc. | Apparatus and method for preparing microparticles using in-line solvent extraction |
| AU784541B2 (en) | 1999-11-29 | 2006-04-27 | Adolor Corporation | Novel methods and compositions involving opioids and antagonists thereof |
| ES2572332T3 (es) | 2000-10-31 | 2016-05-31 | Rensselaer Polytech Inst | 2,6-metano-3-benzazocinas sustituidas en posición 8 y morfinanos sustituidos en posición 3 como ligandos de receptores opioides |
| US7375082B2 (en) | 2002-02-22 | 2008-05-20 | Shire Llc | Abuse-resistant hydrocodone compounds |
| PT1485051E (pt) | 2002-03-20 | 2008-07-09 | Euro Celtique Sa | Processo de administração da buprenorfina para o tratamento da depressão |
| DE60302157T2 (de) | 2002-05-30 | 2006-07-27 | Eli Lilly And Co., Indianapolis | Opioidrezeptorantagonisten |
| DE10229842A1 (de) | 2002-07-03 | 2004-02-05 | Helmut Prof. Dr. Schmidhammer | Morphinanderivate und deren quartäre Ammoniumsalze substituiert in Position 14, Herstellungsverfahren und Verwendung |
| WO2004007449A1 (en) | 2002-07-16 | 2004-01-22 | Rensselaer Polytechnic Institute | Process for conversion of phenols to carboxamides via the succinimide esters |
| WO2004045562A2 (en) | 2002-11-18 | 2004-06-03 | The Mclean Hospital Corporation | Mixed kappa/mu opioids and uses thereof |
| US20040192715A1 (en) | 2003-02-05 | 2004-09-30 | Mark Chasin | Methods of administering opioid antagonists and compositions thereof |
| EP2316456B1 (en) * | 2003-04-29 | 2017-06-14 | Orexigen Therapeutics, Inc. | Compositions for affecting weight loss comprising an opioid antagonist and bupropion |
| EA200601414A1 (ru) * | 2004-04-22 | 2007-02-27 | Мор Рисерч Эппликейшнз Лтд. | Способ контроля потребления пищи |
| CN1984879B (zh) | 2004-05-14 | 2011-07-27 | 詹森药业有限公司 | 甲酰胺基阿片样化合物 |
| US20060063792A1 (en) | 2004-09-17 | 2006-03-23 | Adolor Corporation | Substituted morphinans and methods of their use |
| EP1817291A1 (en) | 2004-11-05 | 2007-08-15 | Rensselaer Polytechnic Institute | 4-hydroxybenzomorphans |
| ES2714198T3 (es) | 2005-03-07 | 2019-05-27 | Univ Chicago | Uso de antagonistas opioideos para atenuar la proliferación y la migración de células endoteliales |
| JP5266051B2 (ja) | 2005-07-21 | 2013-08-21 | レンセラール ポリテクニック インスティチュート | 大きい置換基を有する非フェノール性オピオイド |
| US20070099947A1 (en) | 2005-11-03 | 2007-05-03 | Alkermes, Inc. | Methods and compositions for the treatment of brain reward system disorders by combination therapy |
| WO2007067714A2 (en) * | 2005-12-08 | 2007-06-14 | The Mclean Hospital Corporation | Treatment of sequelae of psychiatric disorders |
| WO2007089934A2 (en) | 2006-02-01 | 2007-08-09 | Alkermes, Inc. | Methods of treating alcoholism and alcohol related disorders using combination drug therapy and swellable polymers |
| WO2008036172A1 (en) | 2006-09-20 | 2008-03-27 | Mallinckrodt Inc. | Preparation of substituted morphinan-6-ones and salts and intermediates thereof |
| DK2073636T3 (da) | 2006-10-17 | 2012-11-19 | Penick Corp | Fremgangsmåde til fremstilling af oxymorphon |
| WO2008070462A2 (en) | 2006-11-22 | 2008-06-12 | Progenics Pharmaceuticals, Inc. | N-oxides of 4,5-epoxy-morphinanium analogs |
| US9040726B2 (en) | 2007-03-06 | 2015-05-26 | Mallinckrodt Llc | Process for the preparation of quaternary N-alkyl morphinan alkaloid salts |
| PL2134330T3 (pl) | 2007-03-19 | 2013-10-31 | Acadia Pharm Inc | Kombinacje odwrotnych agonistów i antagonistów 5-HT2A z antypsychotykami |
| AU2008255049A1 (en) | 2007-05-16 | 2008-11-27 | Rensselaer Polytechnic Institute | Fused-ring heterocycle opioids |
| WO2009009083A1 (en) | 2007-07-12 | 2009-01-15 | The Mclean Hospital Corporation | R(-)-2-methoxy-11-hydroxyaporphine and derivatives thereof |
| BRPI0815020A2 (pt) | 2007-08-09 | 2015-03-10 | Rensselaer Polytech Inst | Composto, e, métodos de aliviar um efeito colateral de um opiato em um paciente que recebeu um opiato, e de melhorar função do intestino pós-operatório em um paciente que se submeteu a cirurgia. |
| JP2011512360A (ja) | 2008-02-14 | 2011-04-21 | アルカーメス，インコーポレイテッド | 選択的オピオイド化合物 |
| WO2009126931A2 (en) | 2008-04-11 | 2009-10-15 | Xvasive, Inc. | Combination therapy for bipolar disorder |
| US20100190817A1 (en) | 2008-07-21 | 2010-07-29 | Rensselaer Polytechnic Institute | Large substituent, non-phenolic amine opioids |
| AU2009342654B2 (en) | 2009-03-19 | 2013-09-05 | Alkermes Pharma Ireland Limited | Morphinan derivatives with high oral bioavailability |
| US20120149724A1 (en) | 2009-06-04 | 2012-06-14 | The General Hospital Corporation | Modulating endogenous beta-endorphin levels |
| WO2010151689A1 (en) | 2009-06-25 | 2010-12-29 | Alkermes, Inc. | Heterocyclic compounds for the treatment of neurological and psychological disorders |
| WO2011068594A1 (en) | 2009-12-04 | 2011-06-09 | Alkermes, Inc. | Morphinan derivatives for the treatment of drug overdose |
| AU2011232628B2 (en) | 2010-03-22 | 2015-04-09 | Rensselaer Polytechnic Institute | Morphinane derivatives containing a carboxamide group as opioid receptor ligands |
| JP5728084B2 (ja) | 2010-07-08 | 2015-06-03 | アルカーメス ファーマ アイルランド リミテッド | 置換モルフィナンの合成のための方法 |
| PL2601196T3 (pl) | 2010-08-04 | 2014-09-30 | Mallinckrodt Llc | N-demetylowanie 6-ketomorfinanów |
| TR201900097T4 (tr) | 2010-08-23 | 2019-02-21 | Alkermes Pharma Ireland Ltd | Anti̇psi̇koti̇k i̇le i̇ndüklenen ki̇lo artişini tedavi̇ etmeye yöneli̇k yöntemler. |
| JP6091426B2 (ja) | 2010-12-23 | 2017-03-08 | フェニックス ファーマラブス インク | 鎮痛剤として有用な新規モルフィナン類 |
| US9211293B2 (en) | 2011-12-15 | 2015-12-15 | Alkermes Pharma Ireland Limited | Opioid agonist antagonist combinations |
| ES2791764T3 (es) | 2011-12-15 | 2020-11-05 | Alkermes Pharma Ireland Ltd | Composiciones de buprenorfina y antagonistas del receptor de opioides mu |
| NZ631018A (en) | 2013-05-24 | 2017-12-22 | Alkermes Pharma Ireland Ltd | Morphan and morphinan analogues, and methods of use |
| WO2014190271A2 (en) | 2013-05-24 | 2014-11-27 | Alkermes Pharma Ireland Limted | Methods for treating depressive symptoms |
-
2011
- 2011-08-23 TR TR2019/00097T patent/TR201900097T4/tr unknown
- 2011-08-23 AU AU2011293502A patent/AU2011293502B2/en active Active
- 2011-08-23 DK DK11820517.8T patent/DK2608670T3/en active
- 2011-08-23 DK DK18198977.3T patent/DK3446565T3/da active
- 2011-08-23 PT PT11820517T patent/PT2608670T/pt unknown
- 2011-08-23 WO PCT/US2011/048794 patent/WO2012027359A1/en active Application Filing
- 2011-08-23 PL PL11820517T patent/PL2608670T3/pl unknown
- 2011-08-23 PT PT181989773T patent/PT3446565T/pt unknown
- 2011-08-23 US US13/215,718 patent/US8778960B2/en active Active
- 2011-08-23 LT LTEP11820517.8T patent/LT2608670T/lt unknown
- 2011-08-23 RS RS20240080A patent/RS65091B1/sr unknown
- 2011-08-23 ES ES11820517T patent/ES2705726T3/es active Active
- 2011-08-23 EP EP18198977.3A patent/EP3446565B1/en active Active
- 2011-08-23 SI SI201131664T patent/SI2608670T1/sl unknown
- 2011-08-23 NZ NZ606730A patent/NZ606730A/en unknown
- 2011-08-23 CA CA2807965A patent/CA2807965C/en active Active
- 2011-08-23 RS RS20190080A patent/RS58312B1/sr unknown
- 2011-08-23 HU HUE11820517A patent/HUE041981T2/hu unknown
- 2011-08-23 JP JP2013526092A patent/JP5684388B2/ja active Active
- 2011-08-23 SI SI201132099T patent/SI3446565T1/sl unknown
- 2011-08-23 FI FIEP18198977.3T patent/FI3446565T3/fi active
- 2011-08-23 PL PL18198977.3T patent/PL3446565T3/pl unknown
- 2011-08-23 HR HRP20240109TT patent/HRP20240109T1/hr unknown
- 2011-08-23 EP EP23204861.1A patent/EP4306164A3/en active Pending
- 2011-08-23 EP EP11820517.8A patent/EP2608670B1/en active Active
- 2011-08-23 LT LTEP18198977.3T patent/LT3446565T/lt unknown
-
2014
- 2014-06-05 US US14/297,171 patent/US9126977B2/en active Active
-
2015
- 2015-04-15 AU AU2015201907A patent/AU2015201907B2/en active Active
- 2015-07-30 US US14/813,260 patent/US9517235B2/en active Active
-
2016
- 2016-11-03 US US15/342,263 patent/US9943514B2/en active Active
-
2017
- 2017-01-20 AU AU2017200396A patent/AU2017200396B2/en active Active
-
2018
- 2018-03-16 US US15/923,084 patent/US10300054B2/en active Active
- 2018-04-05 AU AU2018202410A patent/AU2018202410B2/en active Active
-
2019
- 2019-01-16 CY CY191100054T patent/CY1121128T1/el unknown
- 2019-01-25 HR HRP20190169TT patent/HRP20190169T1/hr unknown
- 2019-04-22 US US16/390,531 patent/US10716785B2/en active Active
-
2020
- 2020-06-12 US US16/899,708 patent/US11185541B2/en active Active
- 2020-10-15 US US17/071,166 patent/US11351166B2/en active Active
- 2020-10-15 US US17/071,236 patent/US11241425B2/en active Active
-
2021
- 2021-10-20 US US17/505,896 patent/US11793805B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20190169T1 (hr) | Postupci liječenja povećanja tjelesne težine inducirane antipsihoticima | |
| HRP20180882T1 (hr) | Sredstva za i postupci liječenja dlbcl | |
| EP2611496A4 (en) | Methods of Treatment | |
| EP2538988A4 (en) | METHOD FOR TISSUE-DECELULARIZATION | |
| EP2533783A4 (en) | COMPOUNDS AND METHODS | |
| EP2523664A4 (en) | COMPOUNDS AND METHODS | |
| EP2635286A4 (en) | METHOD FOR THE TREATMENT OF CANCER | |
| EP2523559A4 (en) | COMPOUNDS AND METHODS | |
| ZA201204641B (en) | Method for preparing and detoxifying | |
| EP2621497A4 (en) | ASSOCIATION TREATMENT FOR ROSE ACNE | |
| IL220594A0 (en) | Treatment method | |
| EP2523560A4 (en) | CONNECTIONS AND METHODS | |
| IL222479A (en) | Tissue Engineering Methods | |
| IL223436A (en) | Methods for preparing tetranor - pgdm and tetranor - pgjm | |
| EP2654793A4 (en) | METHODS AND COMPOSITIONS FOR THE TREATMENT OF LESIONS | |
| GB201020805D0 (en) | Radiotherapeutic apparatus | |
| GB201009479D0 (en) | Anti-malarial implants |