DK3446565T3 - Fremgangsmåder til behandling af antipsykotika-induceret vægtøgning - Google Patents

Fremgangsmåder til behandling af antipsykotika-induceret vægtøgning Download PDF

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Publication number
DK3446565T3
DK3446565T3 DK18198977.3T DK18198977T DK3446565T3 DK 3446565 T3 DK3446565 T3 DK 3446565T3 DK 18198977 T DK18198977 T DK 18198977T DK 3446565 T3 DK3446565 T3 DK 3446565T3
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Prior art keywords
antipsychotic
approaches
treatment
weight gain
induced weight
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DK18198977.3T
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English (en)
Inventor
Daniel Deaver
Mark Todtenkopf
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Alkermes Pharma Ireland Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/28Morphinans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK18198977.3T 2010-08-23 2011-08-23 Fremgangsmåder til behandling af antipsykotika-induceret vægtøgning DK3446565T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37612010P 2010-08-23 2010-08-23
EP11820517.8A EP2608670B1 (en) 2010-08-23 2011-08-23 Methods for treating antipsychotic-induced weight gain

Publications (1)

Publication Number Publication Date
DK3446565T3 true DK3446565T3 (da) 2024-01-22

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
DK18198977.3T DK3446565T3 (da) 2010-08-23 2011-08-23 Fremgangsmåder til behandling af antipsykotika-induceret vægtøgning
DK11820517.8T DK2608670T3 (da) 2010-08-23 2011-08-23 Fremgangsmåde til behandling af antipsykotikum-induceret vægtstigning

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK11820517.8T DK2608670T3 (da) 2010-08-23 2011-08-23 Fremgangsmåde til behandling af antipsykotikum-induceret vægtstigning

Country Status (19)

Country Link
US (10) US8778960B2 (da)
EP (3) EP3446565B1 (da)
JP (1) JP5684388B2 (da)
AU (4) AU2011293502B2 (da)
CA (1) CA2807965C (da)
CY (1) CY1121128T1 (da)
DK (2) DK3446565T3 (da)
ES (2) ES2705726T3 (da)
FI (1) FI3446565T3 (da)
HR (2) HRP20240109T1 (da)
HU (1) HUE041981T2 (da)
LT (2) LT3446565T (da)
NZ (1) NZ606730A (da)
PL (2) PL2608670T3 (da)
PT (2) PT3446565T (da)
RS (2) RS58312B1 (da)
SI (2) SI3446565T1 (da)
TR (1) TR201900097T4 (da)
WO (1) WO2012027359A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20171415T4 (hr) * 2009-06-25 2023-03-03 Alkermes Pharma Ireland Limited Heterociklični spojevi za liječenje neuroloških i psiholoških poremećaja
SI2506712T1 (sl) 2009-12-04 2019-06-28 Alkermes Pharma Ireland Limited, Derivati morfinana za zdravljenje prevelikega odmerka mamil
HUE041981T2 (hu) * 2010-08-23 2019-06-28 Alkermes Pharma Ireland Ltd Eljárások antipszichotikum által kiváltott súlygyarapodás kezelésére
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
US9656961B2 (en) 2013-05-24 2017-05-23 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
CA2911231C (en) 2013-05-24 2021-12-07 Alkermes Pharma Ireland Limited Morphan and morphinan analogues, and methods of use
WO2020006367A1 (en) * 2018-06-29 2020-01-02 Tufts Medical Center, Inc. Methods and compositions for preventing and treating metabolic syndrome induced by antipsychotic treatment and related diseases and conditions
WO2022101444A1 (en) * 2020-11-12 2022-05-19 Alkermes Pharma Ireland Limited Immediate release multilayer tablet
WO2023105103A1 (es) 2022-06-17 2023-06-15 Mesoestetic Pharma Group, S.L Composición cosmética sinérgica despigmentante de la piel

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US9656961B2 (en) 2013-05-24 2017-05-23 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
CA2911231C (en) 2013-05-24 2021-12-07 Alkermes Pharma Ireland Limited Morphan and morphinan analogues, and methods of use

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Publication number Publication date
US20210046065A1 (en) 2021-02-18
HUE041981T2 (hu) 2019-06-28
EP2608670B1 (en) 2018-10-31
US11241425B2 (en) 2022-02-08
AU2017200396B2 (en) 2018-04-19
PL3446565T3 (pl) 2024-04-02
US11185541B2 (en) 2021-11-30
US9126977B2 (en) 2015-09-08
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CA2807965A1 (en) 2012-03-01
US20190307742A1 (en) 2019-10-10
AU2011293502A1 (en) 2013-02-28
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US8778960B2 (en) 2014-07-15
US20210038594A1 (en) 2021-02-11
US20210015812A1 (en) 2021-01-21
AU2011293502B2 (en) 2015-03-19
PT3446565T (pt) 2024-01-29
LT3446565T (lt) 2024-01-10
US20120077800A1 (en) 2012-03-29
EP4306164A2 (en) 2024-01-17
US20180271855A1 (en) 2018-09-27
EP3446565B1 (en) 2023-11-01
US20160051538A1 (en) 2016-02-25
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AU2015201907B2 (en) 2016-12-22
ES2705726T3 (es) 2019-03-26
AU2015201907A1 (en) 2015-05-07
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ES2969625T3 (es) 2024-05-21
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HRP20190169T1 (hr) 2019-03-22
PT2608670T (pt) 2019-02-01
US11351166B2 (en) 2022-06-07
RS58312B1 (sr) 2019-03-29
PL2608670T3 (pl) 2019-05-31
EP2608670A4 (en) 2014-05-07
US9517235B2 (en) 2016-12-13
AU2017200396A1 (en) 2017-02-09
AU2018202410B2 (en) 2019-02-28
US20140349999A1 (en) 2014-11-27
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HRP20240109T1 (hr) 2024-03-29
US10300054B2 (en) 2019-05-28
US20220280502A1 (en) 2022-09-08
SI3446565T1 (sl) 2024-03-29
NZ606730A (en) 2015-05-29
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US10716785B2 (en) 2020-07-21
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