HUE032746T2 - Vas(III)-szukcinilkazein és eljárás elõállítására - Google Patents
Vas(III)-szukcinilkazein és eljárás elõállítására Download PDFInfo
- Publication number
- HUE032746T2 HUE032746T2 HUE10747311A HUE10747311A HUE032746T2 HU E032746 T2 HUE032746 T2 HU E032746T2 HU E10747311 A HUE10747311 A HU E10747311A HU E10747311 A HUE10747311 A HU E10747311A HU E032746 T2 HUE032746 T2 HU E032746T2
- Authority
- HU
- Hungary
- Prior art keywords
- iron
- casein
- iii
- weight
- caseinsuccinylate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4732—Casein
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Analytical Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Claims (7)
- SzíthbÉaitgi igés^pöííÉök :L ¥asplî)^a|eyfeÂ, ax&döeiienmzve, hogy vastánalom4,3tömegek ás ? Ässgp; Ιβ, oldhatdssie >>a nnntegy «àgybfeè». & ibMtÄiimgdn aránya 5 tömeg%-näl nagyobb, előnyösen nbntegy 5.5 ίδ- nieg^feßäi niägy<>bi?,:
- 2. Az L igénypont szeri*ä vas{iii>sz;ikciniikaz:ein, azzal jellemezve, bogy mlmegy IS iömegbá-nái kisebb, «i<toy8se&mÉiU.gy 10 sômegîke-'ftâl 'klsebtiîr^ôayKégbeit tartalmaz teNItjeszetnsyexddgök:
- 3. Ifiäräs az b . vagy 2- igénypont szerinti vgsilIIbiSÂëiSâlIâaaiîî zö lépesvkoi: a. kæ-ma és bnsostyáökésaymtthidrid magákat ása vízben, ezáltal szó kein iiezett kazein döáiiliá;.a, h, S23ákemltoift'.ks2tó«.:*®aiáitatósa vas(l Ul-klorülciah ezáltal vas(l 1O-W^ctmikazdn előállítása, c. azzoí jellemezve* hagy az. a) lépés: szeriril kezein tisztított kazein, amelynek feher}e«?e«n>ezŐdévi|ktái?8g: 1$. tbmeg%-»á$’ kisebb:, és/vsgy szervetienSzeníWeködésdiyiöikiö: i: tömeg%máí kisebb, és/vagy $tá* nya 3%~nái nagyobb.
- 4. Â 3. igégygönt : szerinti eijázás., azz&i jellemezve, hogy á :fehéneszénn}e?*Ws-tartato mintegy U? tö-meg%-nái kisebb, étvágy a szervedenszemsyezödésdsngiöfííminiegy 0,4 iöíiég%yíálkiáébfe;v
- 5. A 3, tgénypi. * ./vrntt v <t,t&,· tszztil fellerne'x »og<. <> tét r \ et me.mdes.k dia \ »tlta-0"* kaz.c intői, !>e|a>kísasíjpsseudökáppa^kázeiaíói eltérő :léisééjé|é:
- 6 A 3. .igénypont szerinti eljárás, azzal jetkmíezve, hogy a tiszittoít kazein ibsztorbtiitomm aránya mintegy S tSrneg%~nál nagyobb,
- 7. A 3λ igénypont szerltál éijsrss, szzsti j eiknt sxve, hogy a tisztított kezein vagy eftós kazéa ínböí: elésiiiksík 6. A 3. Igénypont szeri»» eprás. amely egy további lépést, a vas(lil)-szukeinfífotzetn vizes oldatának iSikröszitóét tailatetszza. 9, ídydgyászan készítmény,; amely-az !.. vagy 2. Igénypont szerinti vaspin-szitksínilktizeint és legalább egy bKtolbgíasan eitbiadi^stö segédanyagot tartalmaz. íi. A 9. igénypont szerinti készítmény, azzzd jelletnezve, hngy ioiyadék vagy szilire! tonnában, elonybaes folyadék formában va», îî, A 1Ö, igértypont szertsb késziönétty, azzal jellemezve, hogy a ibiyadék itbrnra rrkiat: vagy sznszpetrzlo, előnyösen vizes okim. II-. A 9. igénypont szennii készibnény. szzsi |etiém«zves hogy a : készítmény mintegy Eítitesgíi vasfiHA -SKtikeínilkítzeitá: íarfetlíMzé öklét,: «telpek viszkozitása kisebb, mini mintegy 4ÖÖ tnka-sse, .Äyytat kisebb, tsisí körülibe löt 30Ô mlhoseo: iö. A 942. igénypontök feártselyíke szerMi készítmény., amelybe» a v&síil^szuikfntikazein s MszliötéPy lépes tömegére vistatkoztatott:-:5: mmeg^iS ék IA jömeg% kb*biís. .Äbyösett 6 lőmsg% és 12 iömegék zözötti,: ekí" tiyÖSebfcétr ? tötnegiS és 9ttbma^^::kö^tiiifi^|SnyiS%beri van. 14, A 9-13; igéin-pontakbártttelyike szerinti készttrnétty, f»á8s.>'a^-p»renl^i^.eíiiy^«:í8ills aíkakttazasm, ti..A:9-14. igénypontok bánnsiyike szerími kês?Jtmiay-5msbiàJi><k«zel#èbe»IÂa§'a{feâmmàsmv, 16. A 15. ígényponi szeri mi késztbstéöy az öp steghmárözob alkalmazásm, vérszegénység, tcritességi vashiány, Mszivöd&si zavar szindróma, szoptatás ai®» vasinány ésssüvekedés sotáttiédépö vasiítány kezelésében
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IT2010/000287 WO2012001712A1 (en) | 2010-06-30 | 2010-06-30 | Iron (iii) caseinsuccinylate and method for the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE032746T2 true HUE032746T2 (hu) | 2017-10-30 |
Family
ID=43302532
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE10747311A HUE032746T2 (hu) | 2010-06-30 | 2010-06-30 | Vas(III)-szukcinilkazein és eljárás elõállítására |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20130102529A1 (hu) |
| EP (1) | EP2588488B1 (hu) |
| KR (1) | KR101701830B1 (hu) |
| CN (2) | CN107090011A (hu) |
| AR (1) | AR122394A2 (hu) |
| BR (1) | BR112012032364B1 (hu) |
| CY (1) | CY1119054T1 (hu) |
| DK (1) | DK2588488T3 (hu) |
| ES (1) | ES2628306T3 (hu) |
| HR (1) | HRP20170541T1 (hu) |
| HU (1) | HUE032746T2 (hu) |
| LT (1) | LT2588488T (hu) |
| MA (1) | MA34319B1 (hu) |
| MX (1) | MX346317B (hu) |
| PL (1) | PL2588488T3 (hu) |
| PT (1) | PT2588488T (hu) |
| RS (1) | RS55978B1 (hu) |
| RU (1) | RU2533826C2 (hu) |
| SI (1) | SI2588488T1 (hu) |
| WO (1) | WO2012001712A1 (hu) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102836419B (zh) * | 2012-09-25 | 2014-06-25 | 济川药业集团有限公司 | 一种蛋白琥珀酸铁口服溶液及其制备方法 |
| CN108498454B (zh) * | 2018-04-03 | 2020-11-06 | 济川药业集团有限公司 | 一种蛋白琥珀酸铁口服液及其制备方法 |
| CN111000977A (zh) * | 2019-03-22 | 2020-04-14 | 江苏中天药业有限公司 | 一种蛋白琥珀酸铁固体新剂型及其制备方法 |
| CN112063676B (zh) * | 2020-09-02 | 2021-11-12 | 杭州汉库医药科技有限公司 | 酪蛋白纯化方法和蛋白琥珀酸铁的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1150213B (it) * | 1982-03-02 | 1986-12-10 | Italfarmaco Spa | Derivati di ferro biodisponibile esenti da gastrolesivita',procentimento di preparazione e relative composizioni farmaceutiche |
| IT1222912B (it) | 1987-10-14 | 1990-09-12 | Italfarmaco Spa | Derivati polipeptidici a elevato tenore di ferro e altamente solubili atti alla terapia marziale procedimenti di preparazione e loro forme farmaceutiche |
| IT1297022B1 (it) * | 1997-12-24 | 1999-08-03 | Chemi Spa | Complesso di ferro-succinilcaseina, processo per la sua preparazione e composizioni farmaceutiche che lo contengono |
| ITMO20040200A1 (it) * | 2004-07-29 | 2004-10-29 | Biofer Spa | Processo per la produzione di complessi ferro succinilcaseina e ferro casein acetil aspartilato e loro utilizzato nelle relative composizioni farmaceutiche. |
| CN101321776A (zh) * | 2005-12-06 | 2008-12-10 | 维福（国际）股份公司 | 用于制备铁-琥珀酰酪蛋白的方法 |
| US20070281055A1 (en) * | 2006-06-02 | 2007-12-06 | Patel Gaurav C | Protein Ingredient with Improved Sensory Quality and Nutritionals with Improved Flavor Containing Same |
| TWI346666B (en) * | 2007-12-31 | 2011-08-11 | Animal Technology Inst Taiwan | Method for seperating casein from casein-contained solution |
-
2010
- 2010-06-30 LT LTEP10747311.8T patent/LT2588488T/lt unknown
- 2010-06-30 RU RU2013103799/04A patent/RU2533826C2/ru active
- 2010-06-30 CN CN201611051501.8A patent/CN107090011A/zh active Pending
- 2010-06-30 HU HUE10747311A patent/HUE032746T2/hu unknown
- 2010-06-30 SI SI201031456A patent/SI2588488T1/sl unknown
- 2010-06-30 PT PT107473118T patent/PT2588488T/pt unknown
- 2010-06-30 MA MA35466A patent/MA34319B1/fr unknown
- 2010-06-30 MX MX2012014199A patent/MX346317B/es active IP Right Grant
- 2010-06-30 BR BR112012032364-4A patent/BR112012032364B1/pt active IP Right Grant
- 2010-06-30 DK DK10747311.8T patent/DK2588488T3/en active
- 2010-06-30 WO PCT/IT2010/000287 patent/WO2012001712A1/en active Application Filing
- 2010-06-30 KR KR1020137000100A patent/KR101701830B1/ko active IP Right Grant
- 2010-06-30 EP EP10747311.8A patent/EP2588488B1/en active Active
- 2010-06-30 RS RS20170339A patent/RS55978B1/sr unknown
- 2010-06-30 ES ES10747311.8T patent/ES2628306T3/es active Active
- 2010-06-30 PL PL10747311T patent/PL2588488T3/pl unknown
- 2010-06-30 US US13/805,545 patent/US20130102529A1/en not_active Abandoned
- 2010-06-30 CN CN201080067086.XA patent/CN103025751B/zh active Active
-
2017
- 2017-04-03 HR HRP20170541TT patent/HRP20170541T1/hr unknown
- 2017-06-08 CY CY20171100609T patent/CY1119054T1/el unknown
-
2021
- 2021-03-15 AR ARP210100656A patent/AR122394A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI2588488T1 (sl) | 2017-07-31 |
| WO2012001712A1 (en) | 2012-01-05 |
| HRP20170541T1 (hr) | 2017-06-16 |
| CY1119054T1 (el) | 2018-01-10 |
| MX346317B (es) | 2017-03-15 |
| CN103025751B (zh) | 2016-12-21 |
| BR112012032364A2 (pt) | 2016-10-04 |
| RU2013103799A (ru) | 2014-08-10 |
| RS55978B1 (sr) | 2017-09-29 |
| KR20130136422A (ko) | 2013-12-12 |
| US20130102529A1 (en) | 2013-04-25 |
| BR112012032364B1 (pt) | 2021-08-31 |
| DK2588488T3 (en) | 2017-04-03 |
| AR122394A2 (es) | 2022-09-07 |
| CN103025751A (zh) | 2013-04-03 |
| MX2012014199A (es) | 2013-05-06 |
| KR101701830B1 (ko) | 2017-02-13 |
| EP2588488B1 (en) | 2017-03-15 |
| PL2588488T3 (pl) | 2017-09-29 |
| MA34319B1 (fr) | 2013-06-01 |
| RU2533826C2 (ru) | 2014-11-20 |
| CN107090011A (zh) | 2017-08-25 |
| ES2628306T3 (es) | 2017-08-02 |
| LT2588488T (lt) | 2017-05-10 |
| EP2588488A1 (en) | 2013-05-08 |
| PT2588488T (pt) | 2017-06-26 |
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