HUE028629T2 - Anti-FLT3 antibodies and ways of their use - Google Patents

Anti-FLT3 antibodies and ways of their use Download PDF

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Publication number
HUE028629T2
HUE028629T2 HUE10798340A HUE10798340A HUE028629T2 HU E028629 T2 HUE028629 T2 HU E028629T2 HU E10798340 A HUE10798340 A HU E10798340A HU E10798340 A HUE10798340 A HU E10798340A HU E028629 T2 HUE028629 T2 HU E028629T2
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HU
Hungary
Prior art keywords
antibody
ser
antibodies
thr
val
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Application number
HUE10798340A
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English (en)
Hungarian (hu)
Inventor
Ludger Grosse-Hovest
Hans-Joerg Buehring
Martin Hofmann
Steffen Aulwurm
Grundram Jung
Original Assignee
Synimmune Gmbh
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Filing date
Publication date
Application filed by Synimmune Gmbh filed Critical Synimmune Gmbh
Publication of HUE028629T2 publication Critical patent/HUE028629T2/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/72Increased effector function due to an Fc-modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HUE10798340A 2009-12-23 2010-12-23 Anti-FLT3 antibodies and ways of their use HUE028629T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28952909P 2009-12-23 2009-12-23

Publications (1)

Publication Number Publication Date
HUE028629T2 true HUE028629T2 (en) 2016-12-28

Family

ID=43719470

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE10798340A HUE028629T2 (en) 2009-12-23 2010-12-23 Anti-FLT3 antibodies and ways of their use

Country Status (13)

Country Link
US (1) US9023996B2 (enExample)
EP (1) EP2516468B1 (enExample)
JP (1) JP5944831B2 (enExample)
CN (1) CN102770453B (enExample)
BR (1) BR112012015740B1 (enExample)
CA (1) CA2785178C (enExample)
DK (1) DK2516468T3 (enExample)
EA (1) EA027502B1 (enExample)
ES (1) ES2573642T3 (enExample)
HR (1) HRP20160422T1 (enExample)
HU (1) HUE028629T2 (enExample)
SI (1) SI2516468T1 (enExample)
WO (1) WO2011076922A1 (enExample)

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US20120328612A1 (en) 2012-12-27
CN102770453A (zh) 2012-11-07
HRP20160422T1 (hr) 2016-05-20
CN102770453B (zh) 2014-10-08
EP2516468B1 (en) 2016-03-02
CA2785178C (en) 2019-09-03
EA201290370A1 (ru) 2013-04-30
JP2013515472A (ja) 2013-05-09
EA027502B1 (ru) 2017-08-31
CA2785178A1 (en) 2011-06-30
ES2573642T3 (es) 2016-06-09
WO2011076922A1 (en) 2011-06-30
BR112012015740A2 (pt) 2017-04-25
SI2516468T1 (sl) 2016-06-30
EP2516468A1 (en) 2012-10-31
HK1172910A1 (zh) 2013-05-03
US9023996B2 (en) 2015-05-05
DK2516468T3 (en) 2016-05-23
BR112012015740B1 (pt) 2020-09-29
JP5944831B2 (ja) 2016-07-05

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