HUE028055T2 - Myeloma multiplex feljavított kezelése - Google Patents

Myeloma multiplex feljavított kezelése Download PDF

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Publication number
HUE028055T2
HUE028055T2 HUE07757603A HUE07757603A HUE028055T2 HU E028055 T2 HUE028055 T2 HU E028055T2 HU E07757603 A HUE07757603 A HU E07757603A HU E07757603 A HUE07757603 A HU E07757603A HU E028055 T2 HUE028055 T2 HU E028055T2
Authority
HU
Hungary
Prior art keywords
aplidine
combination
cells
treatment
aplidin
Prior art date
Application number
HUE07757603A
Other languages
English (en)
Inventor
Glynn Thomas Faircloth
Marin Pablo Manuel Aviles
Doreen Lepage
Miguel Izquierdo Jesus San
Atanasio Pandiella
Original Assignee
Pharma Mar Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharma Mar Sa filed Critical Pharma Mar Sa
Publication of HUE028055T2 publication Critical patent/HUE028055T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15—Depsipeptides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
HUE07757603A 2006-02-28 2007-02-28 Myeloma multiplex feljavított kezelése HUE028055T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81360606P 2006-02-28 2006-02-28

Publications (1)

Publication Number Publication Date
HUE028055T2 true HUE028055T2 (hu) 2016-11-28

Family

ID=38459806

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE07757603A HUE028055T2 (hu) 2006-02-28 2007-02-28 Myeloma multiplex feljavított kezelése

Country Status (24)

Country Link
US (1) US8258098B2 (hu)
EP (1) EP2029155B1 (hu)
JP (2) JP5393159B2 (hu)
KR (2) KR20140101014A (hu)
CN (1) CN101389347B (hu)
AU (1) AU2007220050B2 (hu)
CA (1) CA2643238C (hu)
CY (1) CY1117722T1 (hu)
DK (1) DK2029155T3 (hu)
ES (1) ES2575518T3 (hu)
HK (1) HK1127294A1 (hu)
HR (1) HRP20160646T1 (hu)
HU (1) HUE028055T2 (hu)
IL (1) IL193094A (hu)
ME (1) ME02450B (hu)
MX (1) MX2008010999A (hu)
NO (1) NO342012B1 (hu)
NZ (1) NZ571043A (hu)
PL (1) PL2029155T3 (hu)
PT (1) PT2029155E (hu)
RS (1) RS54928B1 (hu)
RU (1) RU2481853C2 (hu)
SI (1) SI2029155T1 (hu)
WO (1) WO2007101235A2 (hu)

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JP2003514025A (ja) * 1999-11-15 2003-04-15 ファルマ・マール・ソシエダード・アノニマ ガンのアプリジン治療
DK2029155T3 (en) 2006-02-28 2016-08-01 Pharma Mar Sa IMPROVED treatment of multiple myeloma
WO2008135793A1 (en) * 2007-05-04 2008-11-13 Pharma Mar S.A. Combination of aplidine and carboplatin in anticancer treatments
JP2011500650A (ja) * 2007-10-19 2011-01-06 ファルマ・マール・ソシエダード・アノニマ 改良された抗腫瘍治療
WO2009109649A1 (en) * 2008-03-07 2009-09-11 Pharma Mar, S.A. Improved antitumoral treatments
JP2011513429A (ja) * 2008-03-07 2011-04-28 ファルマ・マール・ソシエダード・アノニマ 改善された抗癌治療法
CA2786266A1 (en) * 2010-01-05 2011-07-14 Celgene Corporation A combination of an immunomodulatory compound and an artemisinin or a derivative thereof for treating cancer
KR20170096065A (ko) * 2010-11-12 2017-08-23 파르마 마르 에스.에이. 항종양 알칼로이드를 이용한 병용요법
WO2012075211A2 (en) * 2010-12-01 2012-06-07 Niiki Pharma Inc. Combination therapy with a gallium complex
CN104039320B (zh) * 2011-11-09 2019-10-15 百时美施贵宝公司 血液恶性肿瘤用抗-cxcr4抗体的治疗
KR101369936B1 (ko) * 2011-12-28 2014-03-06 연세대학교 산학협력단 탈리도마이드를 포함하는 루프스 신염 치료용 약학 조성물
RU2547999C1 (ru) * 2013-10-28 2015-04-10 Государственное бюджетное учреждение здравоохранения Московской области "Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского" (ГБУЗ МО МОНИКИ им. М.Ф. Владимирского) Способ лечения аденогенного местно-распространенного рака нижнеампулярного отдела прямой кишки
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام
EP3895733A4 (en) * 2018-12-14 2022-03-02 Konica Minolta, Inc. METHOD OF PREDICTING THE ARRIVAL OF A DRUG WITHIN DISEASED TISSUE
CN113018415B (zh) * 2021-03-17 2022-07-01 遵义医科大学 一种药物组合及其应用

Family Cites Families (38)

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US4493796A (en) * 1980-09-12 1985-01-15 Board Of Trustees, Univ. Of Ill. Didemnins A, B, C, and derivatives thereof, as antiviral agents
IT1153974B (it) * 1982-09-23 1987-01-21 Erba Farmitalia Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento
EP0220453B1 (de) * 1985-09-20 1992-04-15 Cernitin S.A. Verwendung von Pflanzenpollenextrakten zur Herstellung von das Wachstum von Tumorzellen hemmenden pharmazeutischen Präparaten und Verfahren zu ihrer Herstellung
US4948791A (en) 1989-04-10 1990-08-14 The Board Of Trustees Of The University Of Illinois Novel Cytotoxic cyclic depsipeptides from the tunicate trididemnum solidum
US20030148933A1 (en) * 1990-10-01 2003-08-07 Pharma Mar S.A. Derivatives of dehydrodidemnin B
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DE4120327A1 (de) 1991-06-20 1992-12-24 Basf Ag Neue peptide, ihre herstellung und verwendung
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AU726146B2 (en) 1996-10-24 2000-11-02 Board Of Trustees Of The University Of Illinois, The Total synthesis of the amino hip analogue of didemnin A
ES2262175T3 (es) 1996-10-24 2006-11-16 The Board Of Trustees Of The University Of Illinois Estudios semisinteticos para dar analogos de didemnina.
US6034058A (en) * 1997-04-15 2000-03-07 Rinehart; Kenneth L. Semi-synthetic alanyl dilemnin analogs
CA2288639A1 (en) * 1997-05-07 1998-11-12 Pharma Mar, S.A. Aplidine as an l-type calcium channel enhancer
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US6635677B2 (en) * 1999-08-13 2003-10-21 Case Western Reserve University Methoxyamine combinations in the treatment of cancer
JP2003514025A (ja) * 1999-11-15 2003-04-15 ファルマ・マール・ソシエダード・アノニマ ガンのアプリジン治療
DK1276491T3 (da) 2000-04-07 2007-02-05 Univ Pennsylvania Tamandarin- og didemnin-analoger og fremgangsmåder til fremstilling og anvendelse af dem
US6509315B1 (en) * 2000-04-07 2003-01-21 The Trustees Of The University Of Pennsylvania Didemnin analogs and fragments and methods of making and using them
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DK2029155T3 (en) 2006-02-28 2016-08-01 Pharma Mar Sa IMPROVED treatment of multiple myeloma
DE102006061344A1 (de) * 2006-12-22 2008-06-26 Robert Bosch Gmbh Kupplungshydraulikkreis
WO2008080956A1 (en) 2006-12-29 2008-07-10 Pharma Mar, S.A. Prognostic molecular markers for the cancer therapy with aplidine
WO2008135793A1 (en) 2007-05-04 2008-11-13 Pharma Mar S.A. Combination of aplidine and carboplatin in anticancer treatments
JP2011500650A (ja) * 2007-10-19 2011-01-06 ファルマ・マール・ソシエダード・アノニマ 改良された抗腫瘍治療
WO2010029158A1 (en) 2008-09-12 2010-03-18 Pharma Mar, S.A. Aplidine in the treatment of chronic myeloproliferative disorders

Also Published As

Publication number Publication date
ME02450B (me) 2016-09-20
WO2007101235A3 (en) 2008-04-03
EP2029155A2 (en) 2009-03-04
KR20080105123A (ko) 2008-12-03
RU2481853C2 (ru) 2013-05-20
EP2029155B1 (en) 2016-04-13
CN101389347A (zh) 2009-03-18
MX2008010999A (es) 2008-09-08
NZ571043A (en) 2012-06-29
NO342012B1 (no) 2018-03-12
CN101389347B (zh) 2013-03-27
DK2029155T3 (en) 2016-08-01
PT2029155E (pt) 2016-06-17
PL2029155T3 (pl) 2016-09-30
NO20084047L (no) 2008-11-25
US8258098B2 (en) 2012-09-04
CY1117722T1 (el) 2017-05-17
JP5393159B2 (ja) 2014-01-22
JP2013199500A (ja) 2013-10-03
AU2007220050A1 (en) 2007-09-07
RS54928B1 (sr) 2016-10-31
US20090246168A1 (en) 2009-10-01
KR20140101014A (ko) 2014-08-18
EP2029155A4 (en) 2009-10-14
CA2643238A1 (en) 2007-09-07
HK1127294A1 (zh) 2009-09-25
JP2009528379A (ja) 2009-08-06
IL193094A (en) 2015-06-30
CA2643238C (en) 2016-05-03
SI2029155T1 (sl) 2016-06-30
RU2008138560A (ru) 2010-04-10
KR101512503B1 (ko) 2015-04-15
AU2007220050B2 (en) 2013-08-29
ES2575518T3 (es) 2016-06-29
WO2007101235A2 (en) 2007-09-07
HRP20160646T1 (hr) 2016-08-12
IL193094A0 (en) 2011-08-01

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