HUE026916T2 - Eljárás pitvarfibrilláció kezelésére - Google Patents

Eljárás pitvarfibrilláció kezelésére Download PDF

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Publication number
HUE026916T2
HUE026916T2 HUE10798436A HUE10798436A HUE026916T2 HU E026916 T2 HUE026916 T2 HU E026916T2 HU E10798436 A HUE10798436 A HU E10798436A HU E10798436 A HUE10798436 A HU E10798436A HU E026916 T2 HUE026916 T2 HU E026916T2
Authority
HU
Hungary
Prior art keywords
ranolazine
dronedarone
atrial
ventricular
heart
Prior art date
Application number
HUE10798436A
Other languages
English (en)
Inventor
Charles Antzelevitch
Luiz Belardinelli
Alexander Burashnikov
John Shryock
Dewan Zeng
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43736345&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE026916(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of HUE026916T2 publication Critical patent/HUE026916T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Claims (3)

  1. SZABABÂLMi 10£KYVON10X
    1. JMn fdtosaá&amp;sss. «yáafefcaa pi$YS?»bsU&amp;# « 0mMà^L·· Més&amp;ëvagy vmb&amp;ïp^wâm. mimk w» sdiöép va», ss *$M» mémmx émxáami vagy amuik ^ys«»raí«s?isg d&amp;pdha# : sé|s vdáptes hatfe* xmmp^mk:ét rtmzativ tst iVié*n hits?«» jss^yyiségsavk 3«ag*:Ssáí s pfcivSS sséssása. g, Rsadsms ässsäs ax ï, igd<>pôm ssensk, ahol s brácsán*« vagy ®mk φ< H.&amp; Aösissxk kiife ys# «gyRS, Ktwsí küÄi Ä- egység, m&amp; sdagsfe #sl &amp; kifesd t fess sps% 4$üßm<: agy tablé??*. R ss L^^oérnknii sW $ érmsémm ^ÿÂk^)s% « txmteik vagy örnkssevst* adages, 4. li&amp;noteis felàsssaâjàsîx ;*. i-x. igêæjpsaiok MtssstW® *s**ssw. »tó «s «dapsk ta^x;.* kàâm&amp; so«. - ïfymé* 3mm**m*> «b***·»« mä so »g · *Μ»>ο&amp;ΰ isoo Sïvô; napOSta. 5. kssßkxs'; RxhxssxáissrK scs 1-4. %έχν'ρί>ηί:Α Itàrxsdvskâ: tsstisy sroí öS saagoit dyoaasxv;.« vagy sM«sk rtma&amp;$èm Mkmm m m * MííusíM \m sû m- i; kêï$m® S3Ö mg mmâm Sê ι*~«ιβ#*»Μ» ®&amp;*»ρ®φ. i 8¾ 1-4· ^#3S^s#rlÉi.'ál#{ tó^agoR^a«^» vagy atmksód æîtsœyMp k;k?Rbd»s 30 sag - JsöíSIbsíül 3M mg nattas, épp adag# «molaxd met-aylsép; ksiniisssk! Jiíkssy feRdjdül 1O0R sagsspsíís, 7. :SRaa^Âà'f«lh«s.r^Msm * A iafevpcn! sa-iHst, add «s adagc-R dtasadsraa vsgy assay vis íasSpyiísssgs kRspiksM 3¾ ssg - IsbSIbssiS 20¾¾¾¾ s^ps&amp;äs" $, Isísslssík Iklkasxfíá'áSík p :l·?. %£hy$»öfc>k y.MípSfylk« :»P|..#i:l: sïys fessdsmáídrntoRIx % {Syàgÿsski'ssSkR Raassdlíáíl sssply íaRskssR '«*07 ·ψρ*&amp; ;;· âpéigÿs^^pôlis.g &amp;? «gy k#gys*«sésæi$«g Hl A R: igéssyp^í sasasíi gyégysasfOssdl RyssííMcid, f rscly: iaW^p:-'A^' <sMm ;WgygdbS vas : : &amp;nn«lálvs. I ;;; il. A 7, igéísy^ sspmss gyôiysæëfessd f<arj*alá«d. aid s ib??x»isd* íöbleüs »îïs&amp;ss vSgy kspsA-aiis fcraysfeiS vsü.
  2. 13, A I.I.. igdjYKJï» íbrmslácd, ahol s tsklcSS vagy fegskök isAsirrísx kóralícKd kl sag , kMSsÄ. S§ tst$ · s3, Á ll, vsgy |3:, sg^ByjxisR sstóai Rísmkiásly.·Φ$ί &amp; ísbRífe S?l *íg ÄäifedüÜ ÍÖOö ss^ «idaydiéblíMiisiül lOO j»g - MsrölfesRi! ?5ô:sig;rs«û4&amp;bsi. s4. A ÍL í#S>p:5sf :sxeH«£l «hiú n SmRí«SS vâgÿ ksgíH«^ safísimsx kŐ^HskdH^íföasg > ; kskülhdid ?S§ K}g ;*áÁ és 200 vagy «tax«k is. A ÿ«]4; jgi»yp*8?ok fes«Yidyik« axöistt fenasíssió, slvi s doscdavos soj» öüOatÄro« l|#okiöísd, :: :: lé. AIMS. s|>éxivpealûkbsmséiyikö XïMM feiuásdk ské s rsáok«« síMjíM MMvkkéaMS fömM&amp;svs.
  3. 17. .A IMS i$s£y$otâôk hém&amp;Xyik» s£«?'i«îi ibftxMsisS, sk;! é àïOÂS-rôR vsgy a&amp;M&amp; s^js asotenssh ffeWvÄsiS. vagy Kyïÿioü ftísxivéátea «;» foísnaiá'lw.
HUE10798436A 2009-12-21 2010-12-20 Eljárás pitvarfibrilláció kezelésére HUE026916T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28873909P 2009-12-21 2009-12-21

Publications (1)

Publication Number Publication Date
HUE026916T2 true HUE026916T2 (hu) 2016-08-29

Family

ID=43736345

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE10798436A HUE026916T2 (hu) 2009-12-21 2010-12-20 Eljárás pitvarfibrilláció kezelésére

Country Status (37)

Country Link
US (3) US8513254B2 (hu)
EP (2) EP2749282B1 (hu)
JP (2) JP5723889B2 (hu)
KR (2) KR20120107995A (hu)
CN (3) CN104147010A (hu)
AP (1) AP3536A (hu)
AR (1) AR079552A1 (hu)
AU (1) AU2010339753B2 (hu)
BR (1) BR112012015499A2 (hu)
CA (1) CA2784028C (hu)
CL (1) CL2012001597A1 (hu)
CR (1) CR20120353A (hu)
CY (1) CY1116511T1 (hu)
DK (1) DK2515900T3 (hu)
EA (2) EA025445B1 (hu)
EC (1) ECSP12012004A (hu)
ES (2) ES2646603T3 (hu)
HK (1) HK1170675A1 (hu)
HR (1) HRP20150644T1 (hu)
HU (1) HUE026916T2 (hu)
IL (1) IL220152A (hu)
ME (1) ME02179B (hu)
MX (2) MX344329B (hu)
NO (1) NO2749282T3 (hu)
NZ (2) NZ627181A (hu)
PE (1) PE20121520A1 (hu)
PL (2) PL2749282T3 (hu)
PT (2) PT2515900E (hu)
RS (1) RS54118B1 (hu)
SG (3) SG181541A1 (hu)
SI (2) SI2749282T1 (hu)
SM (1) SMT201500171B (hu)
TW (1) TWI508726B (hu)
UA (1) UA109887C2 (hu)
UY (1) UY33119A (hu)
WO (1) WO2011084733A1 (hu)
ZA (1) ZA201204608B (hu)

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AU2003248558B8 (en) 2002-05-21 2009-07-09 Gilead Sciences, Inc. Method of treating diabetes
AU2010276537B2 (en) * 2009-07-27 2015-04-16 Gilead Sciences, Inc. Fused heterocyclic compounds as ion channel modulators
WO2011014525A2 (en) 2009-07-29 2011-02-03 Icu Medical, Inc. Fluid transfer devices and methods of use
WO2011135582A2 (en) * 2010-04-28 2011-11-03 Cadila Healthcare Limited Pharmaceutical compositions of dronedarone
MX2012015096A (es) 2010-07-02 2013-05-28 Gilead Sciences Inc Compuestos heterociclicos fusionados como moduladores del canal ion.
EP2707361B1 (en) 2011-05-10 2017-08-23 Gilead Sciences, Inc. Fused heterocyclic compounds as sodium channel modulators
TWI622583B (zh) 2011-07-01 2018-05-01 基利科學股份有限公司 作為離子通道調節劑之稠合雜環化合物
NO3175985T3 (hu) 2011-07-01 2018-04-28
US20150045305A1 (en) * 2012-01-27 2015-02-12 Gilead Sciences, Inc. Combination therapies using late sodium ion channel blockers and potassium ion channel blockers
WO2014179764A1 (en) * 2013-05-03 2014-11-06 Gilead Sciences, Inc. Method of treating atrial fibrillation
CN105682642A (zh) * 2013-08-02 2016-06-15 吉利德科学公司 雷诺嗪和决奈达隆的药物组合物
EP3068440B1 (en) * 2013-11-15 2020-01-08 Northwestern University Inhibition of oxidative stress in atrial fibrillation
CA2934517C (en) 2013-12-19 2018-10-16 Gilead Sciences, Inc. Fused heterocyclic compounds as ion channel modulators
CN104951870B (zh) * 2015-06-01 2018-11-13 南通科瑞斯生物医药科技有限公司 药物临床前心脏风险评估方法
WO2017147328A1 (en) 2016-02-23 2017-08-31 Portola Pharmaceuticals, Inc. Compounds for binding proprotein convertase subtilisin/kexin type 9 (pcsk9)
WO2017152062A1 (en) 2016-03-04 2017-09-08 Gilead Sciences, Inc. Compositions and combinations of autotaxin inhibitors
US10575744B2 (en) 2017-02-24 2020-03-03 Medtronic Cryocath Lp Pericardial balloon mapping
EP3530182B1 (en) * 2018-02-27 2020-12-09 Nokia Technologies Oy Apparatus and method for determining a change in left ventricular twist of a subject's heart
JP2022518765A (ja) * 2019-01-24 2022-03-16 ノースウエスタン ユニバーシティ 心房細動の遺伝子療法による治療

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Also Published As

Publication number Publication date
TWI508726B (zh) 2015-11-21
UY33119A (es) 2011-07-29
US9056108B2 (en) 2015-06-16
US8754087B2 (en) 2014-06-17
EA201290451A1 (ru) 2013-01-30
CR20120353A (es) 2014-10-07
SG181541A1 (en) 2012-07-30
AR079552A1 (es) 2012-02-01
JP2013515007A (ja) 2013-05-02
EP2515900B1 (en) 2015-04-29
CN102665713B (zh) 2015-02-18
KR20160108611A (ko) 2016-09-19
AP2012006331A0 (en) 2012-06-30
CN104688739A (zh) 2015-06-10
UA109887C2 (uk) 2015-10-26
CA2784028A1 (en) 2011-07-14
MX2012007052A (es) 2012-07-30
TW201136586A (en) 2011-11-01
CY1116511T1 (el) 2017-03-15
ES2646603T3 (es) 2017-12-14
PL2749282T3 (pl) 2018-01-31
EP2515900A1 (en) 2012-10-31
EA025445B1 (ru) 2016-12-30
AP3536A (en) 2016-01-13
NZ627181A (en) 2016-02-26
DK2515900T3 (en) 2015-07-27
ME02179B (me) 2015-10-20
AU2010339753A1 (en) 2012-07-12
JP5723889B2 (ja) 2015-05-27
CL2012001597A1 (es) 2013-06-28
PL2515900T3 (pl) 2015-10-30
ECSP12012004A (es) 2012-08-31
BR112012015499A2 (pt) 2016-05-03
CA2784028C (en) 2016-08-23
EP2749282B1 (en) 2017-08-09
IL220152A (en) 2016-11-30
ZA201204608B (en) 2013-02-27
EA201691336A1 (ru) 2017-05-31
HRP20150644T1 (hr) 2015-07-31
US20130317038A1 (en) 2013-11-28
IL220152A0 (en) 2012-07-31
NO2749282T3 (hu) 2018-01-06
SI2749282T1 (sl) 2017-12-29
HK1170675A1 (en) 2013-03-08
CN104147010A (zh) 2014-11-19
US8513254B2 (en) 2013-08-20
US20140323493A1 (en) 2014-10-30
RS54118B1 (en) 2015-12-31
SMT201500171B (it) 2015-09-07
CN102665713A (zh) 2012-09-12
NZ600718A (en) 2014-08-29
JP2015057449A (ja) 2015-03-26
PE20121520A1 (es) 2012-11-26
SG10201408528RA (en) 2015-04-29
SG10201710751TA (en) 2018-02-27
PT2515900E (pt) 2015-07-30
AU2010339753B2 (en) 2015-01-22
MX344329B (es) 2016-12-13
ES2540093T3 (es) 2015-07-08
KR20120107995A (ko) 2012-10-04
US20110183990A1 (en) 2011-07-28
WO2011084733A1 (en) 2011-07-14
PT2749282T (pt) 2017-11-15
EP2749282A1 (en) 2014-07-02
SI2515900T1 (sl) 2015-07-31

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